2. C\u00e1c b\u01b0\u1edbc th\u1ef1c hi\u1ec7n x\u00e9t nghi\u1ec7m karyotype<\/strong><\/h3>\nQu\u00e1 tr\u00ecnh x\u00e9t nghi\u1ec7m karyotype bao g\u1ed3m 8 b\u01b0\u1edbc sau:<\/span><\/p>\n\n- B\u01b0\u1edbc 1: L\u1ea5y m\u1eabu<\/strong><\/li>\n<\/ul>\n
B\u01b0\u1edbc \u0111\u1ea7u ti\u00ean trong vi\u1ec7c th\u1ef1c hi\u1ec7n m\u1ed9t karyotype l\u00e0 thu th\u1eadp m\u1eabu. \u1ede tr\u1ebb s\u01a1 sinh, m\u1eabu m\u00e1u ch\u1ee9a h\u1ed3ng c\u1ea7u, b\u1ea1ch c\u1ea7u v\u00e0 huy\u1ebft thanh s\u1ebd \u0111\u01b0\u1ee3c thu th\u1eadp. M\u1ed9t karyotype s\u1ebd \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n tr\u00ean c\u00e1c t\u1ebf b\u00e0o b\u1ea1ch c\u1ea7u \u0111ang ph\u00e2n chia t\u00edch c\u1ef1c (tr\u1ea1ng th\u00e1i \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 nguy\u00ean ph\u00e2n). Khi mang thai, m\u1eabu c\u00f3 th\u1ec3 l\u00e0 n\u01b0\u1edbc \u1ed1i \u0111\u01b0\u1ee3c l\u1ea5y trong qu\u00e1 tr\u00ecnh ch\u1ecdc \u1ed1i ho\u1eb7c m\u1ed9t m\u1ea9u nhau thai \u0111\u01b0\u1ee3c l\u1ea5y trong x\u00e9t nghi\u1ec7m sinh thi\u1ebft tua nhau thai. N\u01b0\u1edbc \u1ed1i ch\u1ee9a c\u00e1c t\u1ebf b\u00e0o da c\u1ee7a thai nhi c\u0169ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 t\u1ea1o ra karyotype.<\/span><\/p>\n\n- B\u01b0\u1edbc 2: V\u1eadn chuy\u1ec3n \u0111\u1ebfn ph\u00f2ng th\u00ed nghi\u1ec7m<\/strong><\/li>\n<\/ul>\n
Karyotypes s\u1ebd \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n trong m\u1ed9t ph\u00f2ng th\u00ed nghi\u1ec7m c\u1ee5 th\u1ec3, th\u01b0\u1eddng l\u00e0 ph\u00f2ng th\u00ed nghi\u1ec7m t\u1ebf b\u00e0o h\u1ecdc hay m\u1ed9t ph\u00f2ng th\u00ed nghi\u1ec7m nghi\u00ean c\u1ee9u nhi\u1ec5m s\u1eafc th\u1ec3. Kh\u00f4ng ph\u1ea3i t\u1ea5t c\u1ea3 c\u00e1c b\u1ec7nh vi\u1ec7n \u0111\u1ec1u c\u00f3 ph\u00f2ng th\u00ed nghi\u1ec7m t\u1ebf b\u00e0o h\u1ecdc. N\u1ebfu b\u1ec7nh vi\u1ec7n ho\u1eb7c c\u01a1 s\u1edf y t\u1ebf c\u1ee7a b\u1ea1n kh\u00f4ng c\u00f3 ph\u00f2ng th\u00ed nghi\u1ec7m t\u1ebf b\u00e0o h\u1ecdc ri\u00eang, m\u1eabu x\u00e9t nghi\u1ec7m s\u1ebd \u0111\u01b0\u1ee3c g\u1eedi \u0111\u1ebfn ph\u00f2ng th\u00ed nghi\u1ec7m chuy\u00ean ph\u00e2n t\u00edch karyotype. M\u1eabu \u0111\u01b0\u1ee3c ph\u00e2n t\u00edch b\u1edfi c\u00e1c nh\u00e0 c\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o h\u1ecdc \u0111\u01b0\u1ee3c \u0111\u00e0o t\u1ea1o \u0111\u1eb7c bi\u1ec7t ho\u1eb7c c\u00e1c b\u00e1c s\u0129 di truy\u1ec1n y h\u1ecdc.<\/span><\/p>\n\n- B\u01b0\u1edbc 3: T\u00e1ch t\u1ebf b\u00e0o<\/strong><\/li>\n<\/ul>\n
\u0110\u1ec3 ph\u00e2n t\u00edch nhi\u1ec5m s\u1eafc th\u1ec3, m\u1eabu ph\u1ea3i ch\u1ee9a c\u00e1c t\u1ebf b\u00e0o \u0111ang ph\u00e2n chia t\u00edch c\u1ef1c. Trong m\u00e1u c\u00f3 ch\u1ee9a c\u00e1c t\u1ebf b\u00e0o b\u1ea1ch c\u1ea7u t\u00edch c\u1ef1c ph\u00e2n chia. H\u1ea7u h\u1ebft c\u00e1c t\u1ebf b\u00e0o c\u1ee7a thai nhi c\u0169ng t\u00edch c\u1ef1c ph\u00e2n chia. Sau khi m\u1eabu \u0111\u01b0\u1ee3c v\u1eadn chuy\u1ec3n \u0111\u1ebfn ph\u00f2ng th\u00ed nghi\u1ec7m t\u1ebf b\u00e0o h\u1ecdc, c\u00e1c t\u1ebf b\u00e0o kh\u00f4ng ph\u00e2n chia s\u1ebd \u0111\u01b0\u1ee3c t\u00e1ch ra kh\u1ecfi c\u00e1c t\u1ebf b\u00e0o \u0111ang ph\u00e2n chia b\u1eb1ng c\u00e1c h\u00f3a ch\u1ea5t \u0111\u1eb7c bi\u1ec7t.<\/span><\/p>\n\n- B\u01b0\u1edbc 4: Nu\u00f4i c\u1ea5y t\u1ebf b\u00e0o<\/strong><\/li>\n<\/ul>\n
\u0110\u1ec3 c\u00f3 \u0111\u1ee7 t\u1ebf b\u00e0o d\u00f9ng cho ph\u00e2n t\u00edch, c\u00e1c t\u1ebf b\u00e0o \u0111ang ph\u00e2n chia \u0111\u01b0\u1ee3c nu\u00f4i c\u1ea5y trong m\u00f4i tr\u01b0\u1eddng \u0111\u1eb7c bi\u1ec7t. M\u00f4i tr\u01b0\u1eddng n\u00e0y ch\u1ee9a c\u00e1c h\u00f3a ch\u1ea5t v\u00e0 k\u00edch th\u00edch t\u1ed1 cho ph\u00e9p c\u00e1c t\u1ebf b\u00e0o ph\u00e2n chia v\u00e0 nh\u00e2n l\u00ean. Qu\u00e1 tr\u00ecnh nu\u00f4i c\u1ea5y n\u00e0y c\u00f3 th\u1ec3 m\u1ea5t t\u1eeb 3 \u0111\u1ebfn 4 ng\u00e0y \u0111\u1ed1i v\u1edbi t\u1ebf b\u00e0o m\u00e1u v\u00e0 t\u1ed1i \u0111a 1 tu\u1ea7n \u0111\u1ed1i v\u1edbi t\u1ebf b\u00e0o thai nhi.<\/span><\/p>\n\n- B\u01b0\u1edbc 5: \u0110\u1ed3ng b\u1ed9 h\u00f3a t\u1ebf b\u00e0o<\/strong><\/li>\n<\/ul>\n
Nhi\u1ec5m s\u1eafc th\u1ec3 l\u00e0 m\u1ed9t chu\u1ed7i d\u00e0i DNA c\u1ee7a con ng\u01b0\u1eddi. \u0110\u1ec3 nh\u00ecn th\u1ea5y nhi\u1ec5m s\u1eafc th\u1ec3 d\u01b0\u1edbi k\u00ednh hi\u1ec3n vi, nhi\u1ec5m s\u1eafc th\u1ec3 ph\u1ea3i \u1edf d\u1ea1ng nh\u1ecf g\u1ecdn nh\u1ea5t trong giai \u0111o\u1ea1n ph\u00e2n chia t\u1ebf b\u00e0o (nguy\u00ean ph\u00e2n) \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 k\u1ef3 gi\u1eefa. \u0110\u1ec3 \u0111\u01b0a t\u1ea5t c\u1ea3 c\u00e1c t\u1ebf b\u00e0o \u0111\u1ebfn giai \u0111o\u1ea1n ph\u00e2n chia t\u1ebf b\u00e0o c\u1ee5 th\u1ec3 n\u00e0y, c\u00e1c t\u1ebf b\u00e0o \u0111\u01b0\u1ee3c x\u1eed l\u00fd b\u1eb1ng colchicine \u0111\u1ec3 d\u1eebng qu\u00e1 tr\u00ecnh ph\u00e2n chia t\u1ebf b\u00e0o t\u1ea1i th\u1eddi \u0111i\u1ec3m m\u00e0 c\u00e1c nhi\u1ec5m s\u1eafc th\u1ec3 co xo\u1eafn c\u1ef1c \u0111\u1ea1i.<\/p>\n
\n- B\u01b0\u1edbc 6: Gi\u1ea3i ph\u00f3ng c\u00e1c nhi\u1ec5m s\u1eafc th\u1ec3 ra kh\u1ecfi t\u1ebf b\u00e0o<\/strong><\/li>\n<\/ul>\n
\u0110\u1ec3 nh\u00ecn th\u1ea5y nh\u1eefng nhi\u1ec5m s\u1eafc th\u1ec3 nh\u1ecf g\u1ecdn n\u00e0y d\u01b0\u1edbi k\u00ednh hi\u1ec3n vi, c\u00e1c nhi\u1ec5m s\u1eafc th\u1ec3 ph\u1ea3i n\u1eb1m ngo\u00e0i t\u1ebf b\u00e0o. \u0110i\u1ec1u n\u00e0y \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1eb1ng c\u00e1ch x\u1eed l\u00fd c\u00e1c t\u1ebf b\u00e0o v\u1edbi m\u1ed9t dung d\u1ecbch \u0111\u1eb7c bi\u1ec7t khi\u1ebfn ch\u00fang v\u1ee1 ra, qu\u00e1 tr\u00ecnh n\u00e0y \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n tr\u00ean lam k\u00ednh. C\u00e1c m\u1ea3nh v\u1ee5n c\u00f2n s\u00f3t l\u1ea1i t\u1eeb c\u00e1c t\u1ebf b\u00e0o b\u1ea1ch c\u1ea7u b\u1ecb cu\u1ed1n tr\u00f4i, \u0111\u1ec3 l\u1ea1i c\u00e1c nhi\u1ec5m s\u1eafc th\u1ec3 d\u00ednh v\u00e0o lam k\u00ednh.<\/span><\/p>\n\n- B\u01b0\u1edbc 7: Nhu\u1ed9m nhi\u1ec5m s\u1eafc th\u1ec3<\/strong><\/li>\n<\/ul>\n
Nhi\u1ec5m s\u1eafc th\u1ec3 t\u1ef1 nhi\u00ean kh\u00f4ng c\u00f3 m\u00e0u. \u0110\u1ec3 ph\u00e2n bi\u1ec7t nhi\u1ec5m s\u1eafc th\u1ec3 n\u00e0y v\u1edbi nhi\u1ec5m s\u1eafc th\u1ec3 kh\u00e1c, m\u1ed9t lo\u1ea1i thu\u1ed1c nhu\u1ed9m \u0111\u1eb7c bi\u1ec7t g\u1ecdi l\u00e0 thu\u1ed1c nhu\u1ed9m Giemsa \u0111\u01b0\u1ee3c b\u00f4i l\u00ean lam k\u00ednh. Thu\u1ed1c nhu\u1ed9m Giemsa nhu\u1ed9m c\u00e1c v\u00f9ng nhi\u1ec5m s\u1eafc th\u1ec3 gi\u00e0u baz\u01a1 adenine (A) v\u00e0 thymine (T). Khi \u0111\u01b0\u1ee3c nhu\u1ed9m, c\u00e1c nhi\u1ec5m s\u1eafc th\u1ec3 tr\u00f4ng gi\u1ed1ng nh\u01b0 nh\u1eefng s\u1ee3i d\u00e2y v\u1edbi c\u00e1c d\u1ea3i s\u00e1ng v\u00e0 t\u1ed1i. M\u1ed7i nhi\u1ec5m s\u1eafc th\u1ec3 c\u00f3 m\u1ed9t ki\u1ec3u d\u1ea3i s\u00e1ng v\u00e0 t\u1ed1i c\u1ee5 th\u1ec3 cho ph\u00e9p c\u00e1c nh\u00e0 t\u1ebf b\u00e0o h\u1ecdc ph\u00e2n bi\u1ec7t nhi\u1ec5m s\u1eafc th\u1ec3 n\u00e0y v\u1edbi nhi\u1ec5m s\u1eafc th\u1ec3 kh\u00e1c. M\u1ed7i d\u1ea3i t\u1ed1i ho\u1eb7c s\u00e1ng bao g\u1ed3m h\u00e0ng tr\u0103m gen kh\u00e1c nhau.<\/span><\/p>\n\n- B\u01b0\u1edbc 8: Ph\u00e2n t\u00edch karyotype<\/strong><\/li>\n<\/ul>\n
Sau khi nhi\u1ec5m s\u1eafc th\u1ec3 \u0111\u01b0\u1ee3c nhu\u1ed9m, lam k\u00ednh \u0111\u01b0\u1ee3c \u0111\u1eb7t d\u01b0\u1edbi k\u00ednh hi\u1ec3n vi \u0111\u1ec3 ph\u00e2n t\u00edch. M\u1ed9t b\u1ee9c \u1ea3nh v\u1ec1 c\u00e1c nhi\u1ec5m s\u1eafc th\u1ec3 sau \u0111\u00f3 s\u1ebd \u0111\u01b0\u1ee3c ch\u1ee5p. Khi k\u1ebft th\u00fac qu\u00e1 tr\u00ecnh ph\u00e2n t\u00edch, t\u1ed5ng s\u1ed1 nhi\u1ec5m s\u1eafc th\u1ec3 s\u1ebd \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh v\u00e0 c\u00e1c nhi\u1ec5m s\u1eafc th\u1ec3 s\u1ebd \u0111\u01b0\u1ee3c s\u1eafp x\u1ebfp theo k\u00edch th\u01b0\u1edbc.<\/span><\/p>\n– \u0110\u1ebfm nhi\u1ec5m s\u1eafc th\u1ec3:<\/strong><\/h5>\nB\u01b0\u1edbc \u0111\u1ea7u ti\u00ean c\u1ee7a ph\u00e2n t\u00edch l\u00e0 \u0111\u1ebfm c\u00e1c nhi\u1ec5m s\u1eafc th\u1ec3. H\u1ea7u h\u1ebft m\u1ecdi ng\u01b0\u1eddi c\u00f3 46 nhi\u1ec5m s\u1eafc th\u1ec3. C\u00e1c th\u1ec3 l\u1ec7ch b\u1ed9i s\u1ebd l\u00e0m thay \u0111\u1ed5i s\u1ed1 l\u01b0\u1ee3ng nhi\u1ec5m s\u1eafc th\u1ec3 tr\u00ean karyotype, ch\u1eb3ng h\u1ea1n nh\u01b0 nh\u1eefng ng\u01b0\u1eddi m\u1eafc b\u1ec7nh Down c\u00f3 47 nhi\u1ec5m s\u1eafc th\u1ec3. Do \u0111\u00f3, b\u1eb1ng c\u00e1ch ch\u1ec9 nh\u00ecn v\u00e0o s\u1ed1 l\u01b0\u1ee3ng nhi\u1ec5m s\u1eafc th\u1ec3 tr\u00ean karyotype c\u00f3 th\u1ec3 ch\u1ea9n \u0111o\u00e1n \u0111\u01b0\u1ee3c c\u00e1c t\u00ecnh tr\u1ea1ng \u0111\u1ed9t bi\u1ebfn l\u1ec7ch b\u1ed9i kh\u00e1c nhau.\u00a0<\/span><\/p>\n– S\u1eafp x\u1ebfp nhi\u1ec5m s\u1eafc th\u1ec3<\/strong><\/h5>\nSau khi x\u00e1c \u0111\u1ecbnh s\u1ed1 l\u01b0\u1ee3ng nhi\u1ec5m s\u1eafc th\u1ec3, c\u00e1c nh\u00e0 t\u1ebf b\u00e0o h\u1ecdc s\u1ebd b\u1eaft \u0111\u1ea7u s\u1eafp x\u1ebfp c\u00e1c nhi\u1ec5m s\u1eafc th\u1ec3. \u0110\u1ec3 s\u1eafp x\u1ebfp c\u00e1c nhi\u1ec5m s\u1eafc th\u1ec3, nh\u00e0 nghi\u00ean c\u1ee9u t\u1ebf b\u00e0o h\u1ecdc s\u1ebd so s\u00e1nh chi\u1ec1u d\u00e0i nhi\u1ec5m s\u1eafc th\u1ec3, v\u1ecb tr\u00ed c\u1ee7a t\u00e2m \u0111\u1ed9ng (khu v\u1ef1c m\u00e0 hai nhi\u1ec5m s\u1eafc th\u1ec3 n\u1ed1i v\u1edbi nhau) c\u0169ng nh\u01b0 v\u1ecb tr\u00ed v\u00e0 k\u00edch th\u01b0\u1edbc c\u1ee7a c\u00e1c d\u1ea3i G. C\u00e1c c\u1eb7p nhi\u1ec5m s\u1eafc th\u1ec3 \u0111\u01b0\u1ee3c \u0111\u00e1nh s\u1ed1 t\u1eeb l\u1edbn nh\u1ea5t (s\u1ed1 1) \u0111\u1ebfn nh\u1ecf nh\u1ea5t (s\u1ed1 22). C\u00f3 22 c\u1eb7p nhi\u1ec5m s\u1eafc th\u1ec3, \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 nhi\u1ec5m s\u1eafc th\u1ec3 th\u01b0\u1eddng, kh\u1edbp ch\u00ednh x\u00e1c v\u1edbi nhau. Ngo\u00e0i ra c\u00f2n c\u00f3 c\u00e1c nhi\u1ec5m s\u1eafc th\u1ec3 gi\u1edbi t\u00ednh, n\u1eef c\u00f3 hai nhi\u1ec5m s\u1eafc th\u1ec3 X trong khi nam c\u00f3 X v\u00e0 Y.<\/span><\/p>\n– Ph\u00e2n t\u00edch c\u1ea5u tr\u00fac<\/strong><\/h5>\nNgo\u00e0i vi\u1ec7c xem x\u00e9t t\u1ed5ng s\u1ed1 nhi\u1ec5m s\u1eafc th\u1ec3 th\u01b0\u1eddng v\u00e0 nhi\u1ec5m s\u1eafc th\u1ec3 gi\u1edbi t\u00ednh, nh\u00e0 di truy\u1ec1n t\u1ebf b\u00e0o h\u1ecdc c\u0169ng s\u1ebd xem x\u00e9t c\u1ea5u tr\u00fac c\u1ee7a c\u00e1c nhi\u1ec5m s\u1eafc th\u1ec3 c\u1ee5 th\u1ec3 \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o r\u1eb1ng kh\u00f4ng c\u00f3 v\u1eadt li\u1ec7u di truy\u1ec1n b\u1ecb thi\u1ebfu ho\u1eb7c b\u1ed5 sung c\u0169ng nh\u01b0 c\u00e1c b\u1ea5t th\u01b0\u1eddng v\u1ec1 c\u1ea5u tr\u00fac nh\u01b0 chuy\u1ec3n \u0111o\u1ea1n. S\u1ef1 chuy\u1ec3n \u0111o\u1ea1n x\u1ea3y ra khi m\u1ed9t ph\u1ea7n c\u1ee7a m\u1ed9t nhi\u1ec5m s\u1eafc th\u1ec3 \u0111\u01b0\u1ee3c g\u1eafn v\u00e0o m\u1ed9t nhi\u1ec5m s\u1eafc th\u1ec3 kh\u00e1c. Trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p, hai \u0111o\u1ea1n nhi\u1ec5m s\u1eafc th\u1ec3 \u0111\u01b0\u1ee3c ho\u00e1n \u0111\u1ed5i cho nhau (chuy\u1ec3n v\u1ecb c\u00e2n b\u1eb1ng) v\u00e0 nh\u1eefng l\u1ea7n kh\u00e1c, m\u1ed9t \u0111o\u1ea1n th\u1eeba \u0111\u01b0\u1ee3c th\u00eam v\u00e0o ho\u1eb7c m\u1ea5t \u0111i m\u1ed9t \u0111o\u1ea1n cho nhi\u1ec5m s\u1eafc th\u1ec3 kh\u00e1c.\u00a0<\/span><\/p>\n– K\u1ebft lu\u1eadn k\u1ebft qu\u1ea3 cu\u1ed1i c\u00f9ng<\/strong><\/h5>\nCu\u1ed1i c\u00f9ng, k\u1ebft lu\u1eadn t\u1ed5ng s\u1ed1 nhi\u1ec5m s\u1eafc th\u1ec3 v\u00e0 b\u1ea5t k\u1ef3 b\u1ea5t th\u01b0\u1eddng c\u1ea5u tr\u00fac n\u00e0o v\u1edbi t\u1eebng c\u1eb7p nhi\u1ec5m s\u1eafc th\u1ec3. M\u1ed9t h\u00ecnh \u1ea3nh k\u1ef9 thu\u1eadt s\u1ed1 c\u1ee7a c\u00e1c nhi\u1ec5m s\u1eafc th\u1ec3 \u0111\u01b0\u1ee3c t\u1ea1o ra v\u1edbi t\u1ea5t c\u1ea3 c\u00e1c nhi\u1ec5m s\u1eafc th\u1ec3 \u0111\u01b0\u1ee3c s\u1eafp x\u1ebfp theo s\u1ed1. T\u1eeb \u0111\u00f3 gi\u00fap ng\u01b0\u1eddi \u0111\u1ecdc \u0111\u01b0a ra ch\u1ea9n \u0111o\u00e1n cu\u1ed1i c\u00f9ng cho karyotype c\u1ee7a b\u1ec7nh nh\u00e2n.\u00a0<\/span><\/p>\nT\u00f3m l\u1ea1i, x\u00e9t nghi\u1ec7m karyotype l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p th\u00ed nghi\u1ec7m nh\u1eb1m ph\u00e2n t\u00edch v\u00e0 \u0111\u00e1nh gi\u00e1 b\u1ed9 nhi\u1ec5m s\u1eafc th\u1ec3 c\u1ee7a m\u1ed9t c\u00e1 nh\u00e2n v\u1edbi t\u00ednh \u1ee9ng d\u1ee5ng cao trong y h\u1ecdc gi\u00fap ch\u1ea9n \u0111o\u00e1n r\u1ea5t nhi\u1ec1u b\u1ec7nh l\u00fd do b\u1ea5t th\u01b0\u1eddng s\u1ed1 l\u01b0\u1ee3ng nhi\u1ec5m s\u1eafc th\u1ec3.<\/p>\n","protected":false},"excerpt":{"rendered":"
X\u00e9t nghi\u1ec7m karyotype l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p th\u00ed nghi\u1ec7m d\u00f9ng \u0111\u1ec3 ph\u00e2n t\u00edch v\u00e0 \u0111\u00e1nh gi\u00e1 b\u1ed9 nhi\u1ec5m s\u1eafc th\u1ec3 c\u1ee7a m\u1ed9t c\u00e1 nh\u00e2n v\u1edbi t\u00ednh \u1ee9ng d\u1ee5ng cao trong ch\u1ea9n \u0111o\u00e1n c\u00e1c b\u1ec7nh li\u00ean quan \u0111\u1ebfn \u0111\u1ed9t bi\u1ebfn nhi\u1ec5m s\u1eafc th\u1ec3. B\u00e0i vi\u1ebft s\u1ebd gi\u1edbi thi\u1ec7u t\u1ed5ng quan v\u1ec1 nguy\u00ean l\u00fd, \u1ee9ng d\u1ee5ng v\u00e0 […]<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[33,14],"tags":[3],"yoast_head":"\n
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