{"id":3485,"date":"2023-04-10T12:58:05","date_gmt":"2023-04-10T05:58:05","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=3485"},"modified":"2023-04-13T18:20:50","modified_gmt":"2023-04-13T11:20:50","slug":"cac-xet-nghiem-chan-doan-giang-mai","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/10\/cac-xet-nghiem-chan-doan-giang-mai\/","title":{"rendered":"T\u1ed5ng quan c\u00e1c x\u00e9t nghi\u1ec7m ch\u1ea9n \u0111o\u00e1n Giang mai"},"content":{"rendered":"

R\u1ea5t nhi\u1ec1u k\u1ef9 thu\u1eadt x\u00e9t nghi\u1ec7m ch\u1ea9n \u0111o\u00e1n giang mai \u0111\u00e3 \u0111\u01b0\u1ee3c tri\u1ec3n khai. C\u00f3 th\u1ec3 x\u1ebfp ch\u00fang th\u00e0nh b\u1ed1n lo\u1ea1i: (1) soi tr\u1ef1c ti\u1ebfp d\u01b0\u1edbi k\u00ednh hi\u1ec3n vi khi c\u00f3 sang th\u01b0\u01a1ng hi\u1ec7n di\u1ec7n, (2) ph\u1ea3n \u1ee9ng huy\u1ebft thanh kh\u00f4ng chuy\u00ean bi\u1ec7t d\u00f9ng \u0111\u1ec3 t\u1ea7m so\u00e1t b\u1ec7nh, (3) ph\u1ea3n \u1ee9ng huy\u1ebft thanh chuy\u00ean bi\u1ec7t d\u00f9ng \u0111\u1ec3 kh\u1eb3ng \u0111\u1ecbnh b\u1ec7nh, v\u00e0 (4) ph\u00e1t hi\u1ec7n kh\u00e1ng nguy\u00ean tr\u1ef1c ti\u1ebfp d\u00f9ng trong nghi\u00ean c\u1ee9u v\u00e0 d\u00f9ng l\u00e0m ti\u00eau chu\u1ea9n v\u00e0ng \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 x\u00e9t nghi\u1ec7m.<\/strong><\/p>\n

1. <\/strong>Ch\u1ea9n \u0111o\u00e1n Giang mai b\u1eb1ng k\u1ef9 thu\u1eadt hi\u1ec3n vi tr\u1ef1c ti\u1ebfp:<\/strong><\/h2>\n

V\u1edbi s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a t\u1ed5n th\u01b0\u01a1ng, vi\u1ec7c ph\u00e1t hi\u1ec7n xo\u1eafn khu\u1ea9n tr\u1ef1c ti\u1ebfp l\u00e0 c\u00e1ch ch\u1ea9n \u0111o\u00e1n giang mai d\u1ec5 d\u00e0ng v\u00e0 \u0111\u1eb7c hi\u1ec7u nh\u1ea5t n\u1ebfu ta c\u00f3 th\u1ec3 lo\u1ea1i tr\u1eeb t\u00ecnh tr\u1ea1ng nhi\u1ec5m\u00a0 Treponema kh\u00e1c. Tuy nhi\u00ean, k\u1ebft qu\u1ea3 \u00e2m t\u00ednh ch\u01b0a th\u1ec3 lo\u1ea1i tr\u1eeb b\u1ec7nh giang mai.<\/p>\n

1.1. <\/strong>K\u00ednh hi\u1ec3n vi n\u1ec1n \u0111en:<\/h3>\n

B\u1ec7nh ph\u1ea9m l\u00e0 thanh d\u1ecbch kh\u00f4ng c\u00f3 h\u1ed3ng c\u1ea7u v\u00e0 m\u1ea3nh v\u1ee5n m\u00f4, l\u1ea5y \u1edf t\u1ed5n th\u01b0\u01a1ng s\u0103ng, u l\u1ed3i giang mai, m\u1ea3ng nh\u00e0y, ho\u1eb7c c\u1ed5 t\u1eed cung v\u00e0 \u00e2m \u0111\u1ea1o ch\u1ee9a r\u1ea5t nhi\u1ec1u vi khu\u1ea9n T. pallidum<\/em>. C\u0169ng c\u00f3 th\u1ec3 l\u1ea5y ch\u1ea5t d\u1ecbch h\u00fat t\u1eeb h\u1ea1ch lymph\u00f4 s\u01b0ng g\u1ea7n t\u1ed5n th\u01b0\u01a1ng. Quan s\u00e1t b\u1ec7nh ph\u1ea9m t\u1ee9c th\u00ec sau khi l\u1ea5y. D\u01b0\u1edbi k\u00ednh hi\u1ec3n vi n\u1ec1n \u0111en T. pallidum <\/em>l\u00e0 nh\u1eefng xo\u1eafn khu\u1ea9n m\u1ea3nh, v\u00f2ng xo\u1eafn l\u01b0\u1ee3n kh\u00edt, ch\u1eafc v\u00e0 \u0111\u1ed3ng d\u1ea1ng, n\u00f3 di chuy\u1ec3n gi\u1ed1ng nh\u01b0 m\u0169i khoan b\u1eb1ng c\u00e1ch xoay quanh tr\u1ee5c d\u1ecdc.<\/p>\n

D\u00f9ng k\u00ednh hi\u1ec3n vi n\u1ec1n \u0111en c\u00f3 th\u1ec3 ch\u1ea9n \u0111o\u00e1n \u0111\u01b0\u1ee3c giang mai s\u01a1 k\u1ef3, k\u1ef3 II, giai \u0111o\u1ea1n t\u00e1i ph\u00e1t v\u00e0 giang mai b\u1ea9m sinh.<\/p>\n

\"minh-hoa-xet-nghiem-giang-mai\"
Vi khu\u1ea9n giang mai<\/figcaption><\/figure>\n

1.2. <\/strong>K\u1ef9 thu\u1eadt kh\u00e1ng th\u1ec3 hu\u1ef3nh quang tr\u1ef1c ti\u1ebfp:<\/h3>\n

D\u00f9ng kh\u00e1ng th\u1ec3 \u0111\u1eb7c hi\u1ec7u c\u1ed9ng h\u1ee3p hu\u1ef3nh quang ph\u00e1t hi\u1ec7n T. pallidum <\/em>trong ch\u1ea5t b\u00e0i ti\u1ebft, ch\u1ea5t ti\u1ebft t\u1eeb t\u1ed5n th\u01b0\u01a1ng, trong m\u00f4 v\u00e0 d\u1ecbch c\u01a1 th\u1ec3, trong v\u1ebft lo\u00e9t \u1edf mi\u1ec7ng v\u00e0 ru\u1ed9t. K\u1ef9 thu\u1eadt n\u00e0y \u0111\u01b0\u1ee3c d\u00f9ng ch\u1ea9n \u0111o\u00e1n giang mai k\u1ef3 II, giang mai mu\u1ed9n, giang mai b\u1ea9m sinh.<\/p>\n

2. Huy\u1ebft thanh h\u1ecdc<\/strong> ch\u1ea9n \u0111o\u00e1n giang mai: <\/strong><\/h2>\n

L\u00e0 ph\u1ea3n \u1ee9ng \u0111\u01b0\u1ee3c d\u00f9ng ch\u1ee7 y\u1ebfu v\u1edbi huy\u1ebft thanh b\u1ec7nh nh\u00e2n, d\u00f9 v\u1eady m\u1ed9t \u00edt s\u1ea3n ph\u1ea9m th\u01b0\u01a1ng m\u1ea1i c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng huy\u1ebft t\u01b0\u01a1ng.<\/p>\n

2.1. <\/strong>Ph\u1ea3n \u1ee9ng kh\u00f4ng chuy\u00ean bi\u1ec7t:<\/h3>\n

Ph\u00e1t hi\u1ec7n kh\u00e1ng th\u1ec3 IgM v\u00e0 IgG b\u1eb1ng kh\u00e1ng nguy\u00ean c\u00f3 th\u1ec3 l\u00e0 ch\u1ea5t li\u1ec7u lipoid t\u1eeb t\u1ebf b\u00e0o b\u1ecb t\u1ed5n th\u01b0\u01a1ng c\u1ee7a k\u00fd ch\u1ee7 ho\u1eb7c ch\u1ea5t li\u1ec7u lipoprotein ho\u1eb7c cardiolipin c\u1ee7a Treponema hay cardiolipin tr\u00edch t\u1eeb tim b\u00f2. Kh\u00e1ng th\u1ec3 xu\u1ea5t hi\u1ec7n kho\u1ea3ng m\u1ed9t tu\u1ea7n sau s\u0103ng giang mai nh\u01b0ng kh\u00f4ng \u0111\u1eb7c hi\u1ec7u v\u00ec c\u00f2n c\u00f3 \u1edf m\u1ed9t s\u1ed1 b\u1ec7nh kh\u00e1c nh\u01b0 lupus, phong, s\u1edfi,\u2026 Nh\u1eefng k\u1ef9 thu\u1eadt th\u00f4ng d\u1ee5ng x\u00e9t nghi\u1ec7m b\u1ec7nh l\u00e0 ph\u1ea3n \u1ee9ng l\u00ean b\u00f4ng VDRL (Venereal Disease Research Laboratory), ph\u1ea3n \u1ee9ng ng\u01b0ng k\u1ebft latex RPR (Rapid Plasma Reagin). K\u1ef9 thu\u1eadt mi\u1ec5n d\u1ecbch g\u1eafn men ELISA (Enzyme-Linked ImmunoSorbent Assay) kh\u00f4ng \u0111\u1eb7c hi\u1ec7u c\u0169ng \u0111\u01b0\u1ee3c tri\u1ec3n khai d\u1ef1a tr\u00ean c\u0103n b\u1ea3n VDRL g\u1eafn men.<\/p>\n

Ba v\u1ea5n \u0111\u1ec1 ch\u1ee7 y\u1ebfu c\u1ee7a ph\u1ea3n \u1ee9ng kh\u00f4ng chuy\u00ean bi\u1ec7t l\u00e0 hi\u1ec7n t\u01b0\u1ee3ng ti\u1ec1n v\u00f9ng, ph\u1ea3n \u1ee9ng d\u01b0\u01a1ng gi\u1ea3 v\u00e0 b\u00ecnh gi\u1ea3i k\u1ebft qu\u1ea3. Hi\u1ec7n t\u01b0\u1ee3ng ti\u1ec1n v\u00f9ng x\u1ea3y ra \u1edf ch\u1eebng 2% b\u1ec7nh nh\u00e2n giang mai II. \u0110\u00f3 l\u00e0 do kh\u00f4ng c\u00f3 kinh nghi\u1ec7m v\u1edbi huy\u1ebft thanh c\u00f3 h\u1ea1t n\u00ean k\u1ef9 thu\u1eadt vi\u00ean \u0111\u1ecdc sai k\u1ebft qu\u1ea3 ho\u1eb7c l\u00fac th\u1ef1c hi\u1ec7n ph\u1ea3n \u1ee9ng l\u1ea1i nh\u1ecf kh\u00e1ng nguy\u00ean v\u00e0o huy\u1ebft thanh tr\u01b0\u1edbc khi tr\u1ea3i huy\u1ebft thanh v\u00e0o \u00f4. Ngo\u00e0i ra k\u1ebft qu\u1ea3 \u00e2m gi\u1ea3 c\u0169ng x\u1ea3y ra \u1edf giang mai giai \u0111o\u1ea1n s\u1edbm, giang mai mu\u1ed9n v\u00e0 giang mai ti\u1ec1m \u1ea9n.<\/p>\n

Ph\u1ea3n \u1ee9ng d\u01b0\u01a1ng gi\u1ea3 ph\u1ee5 thu\u1ed9c v\u00e0o th\u1eed nghi\u1ec7m v\u00e0 qu\u1ea7n th\u1ec3 kh\u1ea3o s\u00e1t. Kho\u1ea3ng 10% ng\u01b0\u1eddi ch\u00edch ma t\u00fay cho ph\u1ea3n \u1ee9ng giang mai d\u01b0\u01a1ng gi\u1ea3. Ph\u1ea3n \u1ee9ng d\u01b0\u01a1ng gi\u1ea3 t\u1ed3n t\u1ea1i d\u01b0\u1edbi 6 th\u00e1ng li\u00ean h\u1ec7 v\u1edbi vi\u00eam gan, b\u1ec7nh b\u1ea1ch c\u1ea7u \u0111\u01a1n nh\u00e2n nhi\u1ec5m tr\u00f9ng, vi\u00eam ph\u1ed5i do virus, th\u1ee7y \u0111\u1eadu, s\u1edfi, nhi\u1ec5m virus kh\u00e1c, s\u1ed1t r\u00e9t, ch\u1ee7ng ng\u1eeba, c\u00f3 thai, ho\u1eb7c do l\u1ed7i k\u1ef9 thu\u1eadt. Ph\u1ea3n \u1ee9ng d\u01b0\u01a1ng gi\u1ea3 m\u1ea1n t\u00ednh li\u00ean quan c\u00e1c b\u1ec7nh m\u00f4 li\u00ean k\u1ebft hay b\u1ec7nh immunoglobulin b\u1ea5t th\u01b0\u1eddng.<\/p>\n

B\u00ecnh gi\u1ea3i k\u1ebft qu\u1ea3 test kh\u00f4ng chuy\u00ean bi\u1ec7t ph\u1ee5 thu\u1ed9c v\u00e0o qu\u1ea7n th\u1ec3 kh\u1ea3o s\u00e1t v\u00e0 giai \u0111o\u1ea1n b\u1ec7nh. Ph\u1ea3n \u1ee9ng d\u01b0\u01a1ng hay d\u01b0\u01a1ng y\u1ebfu c\u00f3 th\u1ec3 x\u1ea3y ra trong m\u1ecdi th\u1eddi k\u1ef3 b\u1ec7nh. Tuy nhi\u00ean k\u1ebft qu\u1ea3 \u00e2m t\u00ednh c\u00f3 th\u1ec3 x\u1ea3y ra trong th\u1eddi gian \u1ee7 b\u1ec7nh. Khi x\u00e9t nghi\u1ec7m t\u1ea7m so\u00e1t b\u1ec7nh trong qu\u1ea7n th\u1ec3 nguy c\u01a1 th\u1ea5p cho k\u1ebft qu\u1ea3 d\u01b0\u01a1ng t\u00ednh th\u00ec ph\u1ea3i \u0111\u01b0\u1ee3c kh\u1eb3ng \u0111\u1ecbnh b\u1eb1ng th\u1eed nghi\u1ec7m chuy\u00ean bi\u1ec7t.<\/p>\n

M\u1ed9t c\u0103n nguy\u00ean ch\u00ednh g\u00e2y l\u1ea7m l\u1eabn khi s\u1eed d\u1ee5ng th\u1eed nghi\u1ec7m kh\u00f4ng chuy\u00ean bi\u1ec7t l\u00e0 nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng x\u00e9t nghi\u1ec7m qu\u00e1 n\u00f3ng (> 29oC) hay qu\u00e1 l\u1ea1nh (< 23oC). Ngo\u00e0i ra c\u00f2n do b\u1ea3n ch\u1ea5t s\u1ea3n ph\u1ea9m, th\u1eddi gian v\u00e0 v\u1eadn t\u1ed1c ly t\u00e2m.<\/p>\n

B\u1ea3ng so s\u00e1nh \u0111\u1ed9 nh\u1ea1y v\u00e0 \u0111\u1ed9 \u0111\u1eb7c hi\u1ec7u c\u1ee7a nh\u1eefng th\u1eed nghi\u1ec7m kh\u00f4ng chuy\u00ean bi\u1ec7t<\/h4>\n

(kh\u00e1ng nguy\u00ean kh\u00f4ng ph\u1ea3i l\u00e0 T. pallidum<\/em>)<\/p>\n\n\n\n\n\n\n\n
\u0110\u1ed9 nh\u1ea1y (%)<\/td>\n<\/td>\n% \u0111\u1eb7c hi\u1ec7u<\/td>\n<\/tr>\n
Th\u1eed nghi\u1ec7m<\/td>\nK\u1ef3 I<\/td>\nK\u1ef3 II<\/td>\nTi\u1ec1m \u1ea9n<\/td>\nMu\u1ed9n<\/td>\n<\/td>\n<\/tr>\n
VDRL<\/td>\n74-87<\/td>\n100<\/td>\n88-100<\/td>\n37-94<\/td>\n96-99<\/td>\n<\/tr>\n
RPR<\/td>\n77-100<\/td>\n100<\/td>\n95-100<\/td>\n73<\/td>\n93-99<\/td>\n<\/tr>\n
ELISA<\/td>\n90<\/td>\n100<\/td>\n100<\/td>\n<\/td>\n97<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

<\/h3>\n

2.2. <\/strong>Ph\u1ea3n \u1ee9ng huy\u1ebft thanh chuy\u00ean bi\u1ec7t<\/h3>\n

V\u1ec1 m\u1eb7t k\u1ef9 thu\u1eadt th\u00ec ph\u1ee9c t\u1ea1p h\u01a1n v\u00e0 \u0111\u1eaft ti\u1ec1n h\u01a1n ph\u1ea3n \u1ee9ng kh\u00f4ng chuy\u00ean bi\u1ec7t n\u00ean kh\u00f4ng d\u00f9ng \u0111\u1ec3 s\u00e0ng l\u1ecdc giang mai. Ph\u1ea3n \u1ee9ng chuy\u00ean bi\u1ec7t d\u00f9ng kh\u1eb3ng \u0111\u1ecbnh d\u01b0\u01a1ng t\u00ednh c\u1ee7a ph\u1ea3n \u1ee9ng kh\u00f4ng chuy\u00ean bi\u1ec7t, ho\u1eb7c \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng m\u00e0 k\u1ebft qu\u1ea3 test kh\u00f4ng chuy\u00ean bi\u1ec7t \u00e2m t\u00ednh. Kho\u1ea3ng 1% d\u00e2n s\u1ed1 cho k\u1ebft qu\u1ea3 d\u01b0\u01a1ng t\u00ednh gi\u1ea3 v\u1edbi ph\u1ea3n \u1ee9ng chuy\u00ean bi\u1ec7t. Ph\u1ea3n \u1ee9ng chuy\u00ean bi\u1ec7t kh\u00f4ng th\u1ec3 d\u00f9ng theo d\u00f5i tr\u1ecb li\u1ec7u giang mai.<\/p>\n

Ph\u1ea3n \u1ee9ng huy\u1ebft thanh chuy\u00ean bi\u1ec7t s\u1eed d\u1ee5ng nh\u1eefng s\u1ea3n ph\u1ea9m d\u00f9ng T. pallidum <\/em>hay th\u00e0nh ph\u1ea7n c\u1ee7a n\u00f3 l\u00e0m kh\u00e1ng nguy\u00ean, g\u1ed3m ph\u1ea3n \u1ee9ng TPI, FTA-ABS, TPHA, k\u1ef9 thu\u1eadt mi\u1ec5n d\u1ecbch th\u1ea5m (immunoblotting).<\/p>\n

TPI d\u00f9ng d\u00f2ng Nichols c\u1ea5y tr\u00ean d\u1ecbch ho\u00e0n th\u1ecf l\u00e0m kh\u00e1ng nguy\u00ean, s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a b\u1ed5 th\u1ec3 v\u00e0 kh\u00e1ng th\u1ec3 \u0111\u1eb7c hi\u1ec7u trong huy\u1ebft thanh b\u1ec7nh nh\u00e2n s\u1ebd l\u00e0m b\u1ea5t \u0111\u1ed9ng c\u00e1c xo\u1eafn khu\u1ea9n s\u1ed1ng. Hi\u1ec7n t\u01b0\u1ee3ng n\u00e0y nh\u00ecn th\u1ea5y \u0111\u01b0\u1ee3c d\u01b0\u1edbi k\u00ednh hi\u1ec3n vi n\u1ec1n \u0111en. Nh\u01b0\u1ee3c \u0111i\u1ec3m th\u1eed nghi\u1ec7m TPI l\u00e0 ph\u1ea3n \u1ee9ng kh\u00e1 ph\u1ee9c t\u1ea1p v\u1ec1 k\u1ef9 thu\u1eadt, t\u1ed1n th\u1eddi gian v\u00e0 \u0111\u1eaft ti\u1ec1n.<\/p>\n

FTA-ABS l\u00e0 k\u1ef9 thu\u1eadt kh\u00e1ng th\u1ec3 h\u00f9ynh quang gi\u00e1n ti\u1ebfp s\u1eed d\u1ee5ng d\u00f2ng Nichols l\u00e0m kh\u00e1ng nguy\u00ean. Huy\u1ebft thanh b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf kh\u00e1ng th\u1ec3 kh\u00f4ng \u0111\u1eb7c hi\u1ec7u r\u1ed3i ph\u1ee7 l\u00ean kh\u00e1ng nguy\u00ean. Kh\u00e1ng th\u1ec3 \u0111\u1eb7c hi\u1ec7u s\u1ebd bao l\u1ea5y xo\u1eafn khu\u1ea9n. C\u1ed9ng h\u1ee3p (conjugate) g\u1ed3m kh\u00e1ng th\u1ec3 anti-Immunoglobulin ng\u01b0\u1eddi \u0111\u00e3 \u0111\u00e1nh d\u1ea5u hu\u1ef3nh quang \u0111\u01b0\u1ee3c th\u00eam v\u00e0o, g\u1eafn v\u1edbi ph\u1ee9c h\u1ee3p kh\u00e1ng th\u1ec3 b\u1ec7nh nh\u00e2n v\u00e0 xo\u1eafn khu\u1ea9n. K\u1ebft qu\u1ea3 l\u00e0 xo\u1eafn khu\u1ea9n ph\u00e1t s\u00e1ng d\u01b0\u1edbi k\u00ednh hi\u1ec3n vi hu\u1ef3nh quang. K\u1ef9 thu\u1eadt n\u00e0y c\u00f3 nh\u01b0\u1ee3c \u0111i\u1ec3m l\u00e0 nhi\u1ec1u th\u00e0nh ph\u1ea7n ph\u1ea3n \u1ee9ng, \u0111\u00f2i h\u1ecfi ki\u1ec3m tra ch\u1ee9ng nhi\u1ec1u m\u1ee9c \u0111\u1ed9, c\u1ed9ng h\u1ee3p ph\u1ea3i \u0111\u01b0\u1ee3c chu\u1ea9n \u0111\u1ed9 v\u00e0 k\u00ednh hi\u1ec3n vi ph\u1ea3i d\u00f9ng m\u00e0ng l\u1ecdc th\u00edch h\u1ee3p.<\/p>\n

Th\u1eed nghi\u1ec7m ng\u01b0ng k\u1ebft h\u1ed3ng c\u1ea7u (TPHA) d\u00f9ng kh\u00e1ng nguy\u00ean l\u00e0 xo\u1eafn khu\u1ea9n d\u00f2ng Nichols g\u1eafn l\u00ean h\u1ed3ng c\u1ea7u c\u1eebu. Kh\u00e1ng th\u1ec3 \u0111\u1eb7c hi\u1ec7u trong huy\u1ebft thanh b\u1ec7nh nh\u00e2n cho v\u00e0o s\u1ebd l\u00e0m ng\u01b0ng k\u1ebft h\u1ed3ng c\u1ea7u. Ph\u1ea3n \u1ee9ng n\u00e0y \u0111\u01a1n gi\u1ea3n, r\u1ebb ti\u1ec1n h\u01a1n v\u00e0 \u00edt ph\u1ea3n \u1ee9ng d\u01b0\u01a1ng gi\u1ea3 h\u01a1n FTA-ABS.\u00a0 Ng\u00e0y nay \u0111\u00e3 c\u00f3 ph\u1ea3n \u1ee9ng TPHA t\u1ef1 \u0111\u1ed9ng, \u0111\u01b0\u1ee3c nh\u1eadn \u0111\u1ecbnh l\u00e0 \u0111\u1eb7c hi\u1ec7u \u00edt nh\u1ea5t g\u1ea5p \u0111\u00f4i test RPR.<\/p>\n

Ngo\u00e0i ra, k\u1ef9 thu\u1eadt ELISA c\u0169ng \u0111\u01b0\u1ee3c v\u1eadn d\u1ee5ng v\u1edbi kh\u00e1ng nguy\u00ean \u0111\u1eb7c hi\u1ec7u l\u00e0 nh\u1eefng protein m\u00e0ng c\u1ee7a T. pallidum<\/em>. Ho\u1eb7c trong k\u1ef9 thu\u1eadt th\u1ea5m mi\u1ec5n d\u1ecbch, protein kh\u00e1ng nguy\u00ean t\u1eeb xo\u1eafn khu\u1ea9n \u0111\u01b0\u1ee3c \u0111i\u1ec7n di ly tr\u00edch v\u00e0 chuy\u1ec3n sang m\u00e0ng nitrocellulose \u0111\u1ec3 t\u1ea1o n\u00ean b\u1ea3n th\u1ea5m kh\u00e1ng nguy\u00ean \u0111\u1eb7c hi\u1ec7u.<\/p>\n

Ph\u1ea3n \u1ee9ng huy\u1ebft thanh chuy\u00ean bi\u1ec7t c\u00f3 th\u1ec3 cho k\u1ebft qu\u1ea3 d\u01b0\u01a1ng gi\u1ea3 (< 1%) v\u1edbi nh\u1eefng tr\u1ea1ng th\u00e1i nh\u01b0 lupus ban \u0111\u1ecf h\u1ec7 th\u1ed1ng, lupus do thu\u1ed1c, b\u1ec7nh phong, tu\u1ed5i gi\u00e0, ng\u01b0\u1eddi nghi\u1ec7n. Ngo\u00e0i ra, kho\u1ea3ng 85% ng\u01b0\u1eddi b\u1ec7nh giang mai \u0111\u00e3 \u0111i\u1ec1u tr\u1ecb th\u00e0nh c\u00f4ng c\u00f2n cho k\u1ebft qu\u1ea3 d\u01b0\u01a1ng t\u00ednh v\u1edbi c\u00e1c ph\u1ea3n \u1ee9ng chuy\u00ean bi\u1ec7t nhi\u1ec1u n\u0103m v\u1ec1 sau.<\/p>\n

3. C\u00e1c k\u1ef9 thu\u1eadt ch\u1ea9n \u0111o\u00e1n Giang mai kh\u00e1c: <\/strong><\/h2>\n

Ti\u00eam b\u1ec7nh ph\u1ea9m v\u00e0o \u0111\u1ed9ng v\u1eadt th\u1ef1c nghi\u1ec7m, d\u00f9ng \u0111o\u1ea1n d\u00f2 DNA, s\u1eed d\u1ee5ng k\u1ef9 thu\u1eadt PCR,\u2026<\/p>\n

Ngu\u1ed3n: PGS.TS V\u00f5 Th\u1ecb Chi Mai<\/p>\n

B\u1ec7nh vi\u1ec7n \u0110a khoa Qu\u1ed1c t\u1ebf Vinmec<\/b><\/a>\u00a0c\u00f3 cung c\u1ea5p G\u00f3i Kh\u00e1m, S\u00e0ng l\u1ecdc c\u00e1c b\u1ec7nh x\u00e3 h\u1ed9i gi\u00fap cho kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 ph\u00e1t hi\u1ec7n s\u1edbm c\u00e1c b\u1ec7nh l\u00fd v\u00e0 c\u00f3 h\u01b0\u1edbng \u0111i\u1ec1u tr\u1ecb hi\u1ec7u qu\u1ea3, ng\u0103n ng\u1eeba bi\u1ebfn ch\u1ee9ng nguy hi\u1ec3m.\u00a0G\u00f3i kh\u00e1m s\u00e0ng l\u1ecdc c\u00e1c b\u1ec7nh x\u00e3 h\u1ed9i<\/b><\/a>\u00a0t\u1ea1i Vinmec d\u00e0nh cho m\u1ecdi l\u1ee9a tu\u1ed5i, c\u1ea3 nam gi\u1edbi v\u00e0 n\u1eef gi\u1edbi.<\/p>\n","protected":false},"excerpt":{"rendered":"

R\u1ea5t nhi\u1ec1u k\u1ef9 thu\u1eadt x\u00e9t nghi\u1ec7m ch\u1ea9n \u0111o\u00e1n giang mai \u0111\u00e3 \u0111\u01b0\u1ee3c tri\u1ec3n khai. C\u00f3 th\u1ec3 x\u1ebfp ch\u00fang th\u00e0nh b\u1ed1n lo\u1ea1i: (1) soi tr\u1ef1c ti\u1ebfp d\u01b0\u1edbi k\u00ednh hi\u1ec3n vi khi c\u00f3 sang th\u01b0\u01a1ng hi\u1ec7n di\u1ec7n, (2) ph\u1ea3n \u1ee9ng huy\u1ebft thanh kh\u00f4ng chuy\u00ean bi\u1ec7t d\u00f9ng \u0111\u1ec3 t\u1ea7m so\u00e1t b\u1ec7nh, (3) ph\u1ea3n \u1ee9ng huy\u1ebft thanh chuy\u00ean bi\u1ec7t […]<\/p>\n","protected":false},"author":16,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[27,33],"tags":[3],"yoast_head":"\nT\u1ed5ng quan c\u00e1c x\u00e9t nghi\u1ec7m ch\u1ea9n \u0111o\u00e1n Giang mai - Vinmec<\/title>\n<meta name=\"description\" content=\"X\u00e9t nghi\u1ec7m ch\u1ea9n \u0111o\u00e1n giang mai l\u00e0 gi\u1ea3i ph\u00e1p gi\u00fap ch\u1ea9n \u0111o\u00e1n s\u1edbm b\u1ec7nh, t\u1eeb \u0111\u00f3 k\u1ecbp th\u1eddi \u0111i\u1ec1u tr\u1ecb v\u00e0 ng\u0103n ng\u1eeba l\u00e2y lan b\u1ec7nh ra ngo\u00e0i c\u1ed9ng \u0111\u1ed3ng.\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"T\u1ed5ng quan c\u00e1c x\u00e9t nghi\u1ec7m ch\u1ea9n \u0111o\u00e1n Giang mai - 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