{"id":32830,"date":"2023-05-09T10:16:29","date_gmt":"2023-05-09T03:16:29","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=32830"},"modified":"2023-05-09T10:16:38","modified_gmt":"2023-05-09T03:16:38","slug":"ung-dung-xet-nghiem-dau-an-sinh-hoc-trong-ung-thu","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/05\/09\/ung-dung-xet-nghiem-dau-an-sinh-hoc-trong-ung-thu\/","title":{"rendered":"\u1ee8ng d\u1ee5ng x\u00e9t nghi\u1ec7m d\u1ea5u \u1ea5n sinh h\u1ecdc trong ung th\u01b0"},"content":{"rendered":"

X\u00e9t nghi\u1ec7m d\u1ea5u \u1ea5n sinh h\u1ecdc l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p quan tr\u1ecdng trong ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb ung th\u01b0. \u0110\u00e2y l\u00e0 nh\u1eefng ch\u1ec9 s\u1ed1 sinh h\u1ecdc, k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m c\u00f3 th\u1ec3 cho th\u1ea5y s\u1ef1 b\u1ea5t th\u01b0\u1eddng trong c\u01a1 th\u1ec3, gi\u00fap trong vi\u1ec7c ph\u00e1t hi\u1ec7n, \u0111\u00e1nh gi\u00e1 v\u00e0 theo d\u00f5i s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a ung th\u01b0.<\/strong><\/p>\n

1. Gi\u1edbi thi\u1ec7u v\u1ec1 c\u00e1c d\u1ea5u \u1ea5n sinh h\u1ecdc trong ung th\u01b0<\/h2>\n

D\u1ea5u \u1ea5n sinh h\u1ecdc (biomarker) l\u00e0 b\u1ea5t k\u1ef3 ch\u1ec9 s\u1ed1 sinh h\u1ecdc, d\u1ea5u hi\u1ec7u ho\u1eb7c bi\u1ec3u hi\u1ec7n b\u1ec7nh l\u00fd n\u00e0o trong c\u01a1 th\u1ec3 ho\u1eb7c m\u00f4 b\u1ec7nh ph\u1ea9m c\u1ee7a b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 cho th\u1ea5y s\u1ef1 b\u1ea5t th\u01b0\u1eddng trong ch\u1ee9c n\u0103ng sinh l\u00fd, t\u00ecnh tr\u1ea1ng b\u1ec7nh l\u00fd, ho\u1eb7c \u0111\u00e1p \u1ee9ng c\u1ee7a c\u01a1 th\u1ec3 \u0111\u1ed1i v\u1edbi c\u00e1c t\u00e1c nh\u00e2n b\u00ean ngo\u00e0i.<\/p>\n

C\u00e1c ph\u01b0\u01a1ng ph\u00e1p x\u00e9t nghi\u1ec7m d\u1ea5u \u1ea5n sinh h\u1ecdc bao g\u1ed3m x\u00e9t nghi\u1ec7m m\u00e1u, x\u00e9t nghi\u1ec7m t\u1ebf b\u00e0o. C\u00e1c ch\u1ec9 s\u1ed1 sinh h\u1ecdc n\u00e0y c\u00f3 th\u1ec3 bao g\u1ed3m \u0111o l\u01b0\u1eddng n\u1ed3ng \u0111\u1ed9 c\u00e1c ch\u1ea5t h\u00f3a h\u1ecdc, protein, enzyme, DNA ho\u1eb7c RNA trong m\u00e1u, n\u01b0\u1edbc ti\u1ec3u ho\u1eb7c m\u00f4 b\u1ec7nh ph\u1ea9m.<\/p>\n

Vi\u1ec7c s\u1eed d\u1ee5ng d\u1ea5u \u1ea5n sinh h\u1ecdc trong ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p quan tr\u1ecdng v\u00e0 h\u1eefu \u00edch. N\u00f3 c\u00f3 th\u1ec3 gi\u00fap ph\u00e1t hi\u1ec7n s\u1edbm c\u00e1c b\u1ec7nh l\u00fd \u0111\u1eb7c bi\u1ec7t b\u1ec7nh ung th\u01b0, cung c\u1ea5p th\u00f4ng tin quan tr\u1ecdng \u0111\u1ec3 \u0111\u01b0a ra quy\u1ebft \u0111\u1ecbnh ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb ch\u00ednh x\u00e1c h\u01a1n, \u0111\u00e1nh gi\u00e1 hi\u1ec7u qu\u1ea3 c\u1ee7a ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb, v\u00e0 \u0111\u00e1nh gi\u00e1 nguy c\u01a1 t\u00e1i ph\u00e1t c\u1ee7a b\u1ec7nh.<\/p>\n

Tuy nhi\u00ean, vi\u1ec7c ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb ung th\u01b0 l\u00e0 m\u1ed9t qu\u00e1 tr\u00ecnh ph\u1ee9c t\u1ea1p v\u00e0 c\u1ea7n \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1edfi c\u00e1c chuy\u00ean gia y t\u1ebf c\u00f3 kinh nghi\u1ec7m v\u00e0 \u0111\u01b0\u1ee3c h\u1ed7 tr\u1ee3 b\u1edfi c\u00e1c ph\u01b0\u01a1ng ti\u1ec7n ch\u1ea9n \u0111o\u00e1n hi\u1ec7n \u0111\u1ea1i. Vi\u1ec7c s\u1eed d\u1ee5ng x\u00e9t nghi\u1ec7m n\u00e0y c\u1ea7n \u0111\u01b0\u1ee3c k\u1ebft h\u1ee3p v\u1edbi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p kh\u00e1c \u0111\u1ec3 \u0111\u01b0a ra k\u1ebft lu\u1eadn ch\u1ea9n \u0111o\u00e1n ch\u00ednh x\u00e1c v\u00e0 \u0111\u1ea3m b\u1ea3o s\u1ef1 an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 c\u1ee7a \u0111i\u1ec1u tr\u1ecb.<\/p>\n

2. \u1ee8ng d\u1ee5ng x\u00e9t nghi\u1ec7m d\u1ea5u \u1ea5n sinh h\u1ecdc cho c\u00e1c lo\u1ea1i ung th\u01b0 th\u01b0\u1eddng g\u1eb7p<\/h2>\n

C\u00e1c lo\u1ea1i ung th\u01b0 th\u01b0\u1eddng g\u1eb7p bao g\u1ed3m ung th\u01b0 ph\u1ed5i, ung th\u01b0 v\u00fa, ung th\u01b0 bu\u1ed3ng tr\u1ee9ng, ung th\u01b0 c\u1ed5 t\u1eed cung, ung th\u01b0 d\u1ea1 d\u00e0y, ung th\u01b0 \u0111\u1ea1i tr\u1ef1c tr\u00e0ng, ung th\u01b0 t\u1ee5y, ung th\u01b0 gan, ung th\u01b0 ti\u1ec1n li\u1ec7t tuy\u1ebfn, ung th\u01b0 tuy\u1ebfn gi\u00e1p,\u2026 M\u1ed7i lo\u1ea1i ung th\u01b0 c\u00f3 nh\u1eefng d\u1ea5u \u1ea5n sinh h\u1ecdc \u0111\u1eb7c tr\u01b0ng v\u00e0 c\u00e1c ph\u01b0\u01a1ng ph\u00e1p x\u00e9t nghi\u1ec7m kh\u00e1c nhau. C\u00e1c x\u00e9t nghi\u1ec7m th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong c\u00e1c b\u1ec7nh ung th\u01b0 n\u00e0y bao g\u1ed3m:<\/p>\n

Ung th\u01b0 ph\u1ed5i<\/a>: CEA (carcinoembryonic antigen, protein \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi t\u1ebf b\u00e0o ung th\u01b0 v\u00e0 t\u1ebf b\u00e0o b\u00ecnh th\u01b0\u1eddng trong \u0111\u01b0\u1eddng ti\u00eau h\u00f3a v\u00e0 m\u1ed9t s\u1ed1 c\u01a1 quan kh\u00e1c), CYFRA21-1 (protein \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi t\u1ebf b\u00e0o ung th\u01b0 ph\u1ed5i), NSE (neuron-specific enolase, enzyme \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi c\u00e1c t\u1ebf b\u00e0o th\u1ea7n kinh v\u00e0 t\u1ebf b\u00e0o ung th\u01b0), ProGRP (pro-gastrin-releasing peptide, peptide \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi c\u00e1c t\u1ebf b\u00e0o ung th\u01b0), SCC (squamous cell carcinoma antigen, \u00a0protein \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 bi\u1ec3u m\u00f4 v\u00e0 t\u1ebf b\u00e0o b\u00ecnh th\u01b0\u1eddng)<\/p>\n

Ung th\u01b0 v\u00fa: CEA, CA15-5 (cancer antigen 15-5), Anti-p53 (p53 l\u00e0 m\u1ed9t protein b\u1ea3o v\u1ec7 DNA \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi t\u1ebf b\u00e0o b\u00ecnh th\u01b0\u1eddng v\u00e0 c\u00f3 t\u00e1c d\u1ee5ng ng\u0103n ng\u1eeba s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a t\u1ebf b\u00e0o ung th\u01b0)<\/p>\n

Ung th\u01b0 bu\u1ed3ng tr\u1ee9ng: HE4 (human epididymis protein 4, \u0111\u1eb7c hi\u1ec7u cho ung th\u01b0 bu\u1ed3ng tr\u1ee9ng)\u00a0, CA125 (cancer antigen 125), CA72-4 (cancer antigen 72-4), CEA<\/p>\n

Ung th\u01b0 c\u1ed5 t\u1eed cung: CEA, SCC<\/p>\n

Ung th\u01b0 d\u1ea1 d\u00e0y: CA72-4 (cancer antigen 72-4)\u00a0, CEA<\/p>\n

Ung th\u01b0 \u0111\u1ea1i tr\u1ef1c tr\u00e0ng: CEA, CA19-9 (cancer antigen 19-9)\u00a0, Ca72-4, Anti-pt3<\/p>\n

Ung th\u01b0 t\u1ee5y: CA19-9<\/p>\n

Ung th\u01b0 gan: AFP (alpha-fetoprotein)\u00a0, PIVKA II (protein induced by vitamin K absence or antagonist II, protein \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi c\u00e1c t\u1ebf b\u00e0o gan trong tr\u01b0\u1eddng h\u1ee3p thi\u1ebfu vitamin K ho\u1eb7c c\u00f3 s\u1ef1 \u1ee9c ch\u1ebf vitamin K)<\/p>\n

Ung th\u01b0 ti\u1ec1n li\u1ec7t tuy\u1ebfn: PSA\u00a0(prostate-specific antigen, protein \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi tuy\u1ebfn ti\u1ec1n li\u1ec7t), fPSA<\/p>\n

Ung th\u01b0 tuy\u1ebfn gi\u00e1p: CEA, Calcitonin, Tg, Anti T\u03b1 (T\u03b1 subunit of human chorionic gonadotropin)<\/p>\n

Vi\u1ec7c k\u1ebft h\u1ee3p nhi\u1ec1u lo\u1ea1i d\u1ea5u \u1ea5n c\u00f3 th\u1ec3 l\u00e0m t\u0103ng \u0111\u00e1ng k\u1ec3 hi\u1ec7u qu\u1ea3 ch\u1ea9n \u0111o\u00e1n ung th\u01b0 so v\u1edbi t\u1eebng lo\u1ea1i d\u1ea5u \u1ea5n ri\u00eang r\u1ebd.<\/p>\n

\"mot-so-dau-an-sinh-hoc-trong-ung-thu\"
M\u1ed9t s\u1ed1 d\u1ea5u \u1ea5n sinh h\u1ecdc trong ung th\u01b0<\/figcaption><\/figure>\n

3. L\u1ee3i \u00edch c\u1ee7a x\u00e9t nghi\u1ec7m d\u1ea5u \u1ea5n sinh h\u1ecdc<\/h2>\n

M\u1ed9t trong nh\u1eefng l\u1ee3i \u00edch quan tr\u1ecdng c\u1ee7a d\u1ea5u \u1ea5n sinh h\u1ecdc trong ch\u1ea9n \u0111o\u00e1n ung th\u01b0 l\u00e0 gi\u00fap ph\u00e1t hi\u1ec7n s\u1edbm, gi\u00fap t\u0103ng kh\u1ea3 n\u0103ng \u0111i\u1ec1u tr\u1ecb th\u00e0nh c\u00f4ng v\u00e0 c\u1ea3i thi\u1ec7n d\u1ef1 \u0111o\u00e1n t\u00ecnh tr\u1ea1ng b\u1ec7nh. \u0110\u1eb7c bi\u1ec7t, vi\u1ec7c s\u1eed d\u1ee5ng c\u00e1c d\u1ea5u \u1ea5n n\u00e0y trong s\u00e0ng l\u1ecdc c\u00f3 th\u1ec3 ph\u00e1t hi\u1ec7n s\u1edbm ung th\u01b0 khi ch\u00fang \u0111ang \u1edf giai \u0111o\u1ea1n r\u1ea5t s\u1edbm, tr\u01b0\u1edbc khi b\u1ec7nh nh\u00e2n bi\u1ec3u hi\u1ec7n tri\u1ec7u ch\u1ee9ng. \u0110i\u1ec1u n\u00e0y r\u1ea5t quan tr\u1ecdng trong vi\u1ec7c \u00a0gi\u00fap b\u1ec7nh nh\u00e2n \u0111i\u1ec1u tr\u1ecb k\u1ecbp th\u1eddi v\u00e0 t\u0103ng c\u01a1 h\u1ed9i ph\u1ee5c h\u1ed3i ho\u00e0n to\u00e0n.<\/p>\n

Ngo\u00e0i ra, s\u1eed d\u1ee5ng d\u1ea5u \u1ea5n sinh h\u1ecdc trong ch\u1ea9n \u0111o\u00e1n ung th\u01b0 c\u0169ng gi\u00fap \u0111\u00e1nh gi\u00e1 hi\u1ec7u qu\u1ea3 c\u1ee7a c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb. Khi b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb, s\u1ef1 thay \u0111\u1ed5i ch\u1ec9 s\u1ed1 c\u1ee7a c\u00e1c d\u1ea5u \u1ea5n sinh h\u1ecdc c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 theo d\u00f5i s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a ung th\u01b0 v\u00e0 \u0111\u00e1nh gi\u00e1 hi\u1ec7u qu\u1ea3 c\u1ee7a \u0111i\u1ec1u tr\u1ecb. \u0110i\u1ec1u n\u00e0y gi\u00fap cho b\u00e1c s\u0129 k\u1ecbp th\u1eddi \u0111i\u1ec1u ch\u1ec9nh ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u1ebfu c\u1ea7n thi\u1ebft, \u0111\u1ed3ng th\u1eddi t\u0103ng kh\u1ea3 n\u0103ng th\u00e0nh c\u00f4ng c\u1ee7a \u0111i\u1ec1u tr\u1ecb v\u00e0 gi\u1ea3m nguy c\u01a1 t\u00e1i ph\u00e1t.<\/p>\n

4. K\u1ebft lu\u1eadn<\/h2>\n

K\u1ebft qu\u1ea3 c\u1ee7a c\u00e1c nghi\u00ean c\u1ee9u v\u00e0 th\u1ef1c ti\u1ec5n l\u00e2m s\u00e0ng \u0111\u00e3 ch\u1ec9 ra r\u1eb1ng x\u00e9t nghi\u1ec7m d\u1ea5u \u1ea5n sinh h\u1ecdc l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p quan tr\u1ecdng v\u00e0 h\u1eefu \u00edch trong ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb ung th\u01b0. Vi\u1ec7c s\u1eed d\u1ee5ng x\u00e9t nghi\u1ec7m d\u1ea5u \u1ea5n sinh h\u1ecdc ph\u00f9 h\u1ee3p v\u00e0 li\u00ean t\u1ee5c c\u00f3 th\u1ec3 gi\u00fap ph\u00e1t hi\u1ec7n s\u1edbm v\u00e0 \u0111i\u1ec1u tr\u1ecb th\u00e0nh c\u00f4ng c\u00e1c lo\u1ea1i ung th\u01b0 th\u01b0\u1eddng g\u1eb7p. N\u00f3 cung c\u1ea5p th\u00f4ng tin quan tr\u1ecdng v\u1ec1 t\u00ecnh tr\u1ea1ng b\u1ec7nh c\u1ee7a b\u1ec7nh nh\u00e2n v\u00e0 gi\u00fap \u0111\u01b0a ra quy\u1ebft \u0111\u1ecbnh ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb ch\u00ednh x\u00e1c h\u01a1n. Tuy nhi\u00ean, vi\u1ec7c s\u1eed d\u1ee5ng x\u00e9t nghi\u1ec7m d\u1ea5u \u1ea5n sinh h\u1ecdc c\u1ea7n \u0111\u01b0\u1ee3c k\u1ebft h\u1ee3p v\u1edbi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p kh\u00e1c v\u00e0 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1edfi c\u00e1c chuy\u00ean gia y t\u1ebf c\u00f3 kinh nghi\u1ec7m \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o s\u1ef1 an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 c\u1ee7a \u0111i\u1ec1u tr\u1ecb.<\/p>\n","protected":false},"excerpt":{"rendered":"

X\u00e9t nghi\u1ec7m d\u1ea5u \u1ea5n sinh h\u1ecdc l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p quan tr\u1ecdng trong ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb ung th\u01b0. \u0110\u00e2y l\u00e0 nh\u1eefng ch\u1ec9 s\u1ed1 sinh h\u1ecdc, k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m c\u00f3 th\u1ec3 cho th\u1ea5y s\u1ef1 b\u1ea5t th\u01b0\u1eddng trong c\u01a1 th\u1ec3, gi\u00fap trong vi\u1ec7c ph\u00e1t hi\u1ec7n, \u0111\u00e1nh gi\u00e1 v\u00e0 theo d\u00f5i s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a […]<\/p>\n","protected":false},"author":70,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[6,33],"tags":[],"yoast_head":"\n\u1ee8ng d\u1ee5ng x\u00e9t nghi\u1ec7m d\u1ea5u \u1ea5n sinh h\u1ecdc trong ung th\u01b0 - Vinmec<\/title>\n<meta name=\"description\" content=\"X\u00e9t nghi\u1ec7m d\u1ea5u \u1ea5n sinh h\u1ecdc l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p quan tr\u1ecdng trong ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh ung th\u01b0 th\u01b0\u1eddng g\u1eb7p\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u1ee8ng d\u1ee5ng x\u00e9t nghi\u1ec7m d\u1ea5u \u1ea5n sinh h\u1ecdc trong ung th\u01b0 - 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