{"id":32616,"date":"2023-05-08T04:53:18","date_gmt":"2023-05-07T21:53:18","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=32616"},"modified":"2023-05-08T16:20:43","modified_gmt":"2023-05-08T09:20:43","slug":"hoi-chung-papillon-lefevre-pls-va-implant-nha-khoa","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/05\/08\/hoi-chung-papillon-lefevre-pls-va-implant-nha-khoa\/","title":{"rendered":"H\u1ed9i ch\u1ee9ng Papillon-Lef\u00e8vre (PLS) v\u00e0 Implant nha khoa."},"content":{"rendered":"

H\u1ed9i ch\u1ee9ng Papillon-Lef\u00e8vre (PLS) l\u00e0 m\u1ed9t b\u1ec7nh l\u00fd nghi\u00eam tr\u1ecdng, \u0111\u1eb7c tr\u01b0ng b\u1edfi s\u1ef1 ph\u00e1 h\u1ee7y nhanh ch\u00f3ng ph\u1ee9c h\u1ee3p x\u01b0\u01a1ng \u1ed5 r\u0103ng, \u1ea3nh h\u01b0\u1edfng l\u00ean c\u1ea3 r\u0103ng s\u1eefa l\u1eabn r\u0103ng v\u0129nh vi\u1ec5n. Nh\u1ed5 s\u1edbm c\u00e1c r\u0103ng v\u0129nh vi\u1ec5n v\u00e0 ph\u1ee5c h\u1ed3i b\u1eb1ng ph\u1ee5c h\u00ecnh \u0111\u01b0\u1ee3c xem l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p gi\u1ea3i quy\u1ebft trong t\u00ecnh hu\u1ed1ng n\u00e0y. Kh\u00f4ng c\u00f3 nhi\u1ec1u b\u00e1o c\u00e1o ca m\u00f4 t\u1ea3 v\u1ec1 vi\u1ec7c \u0111\u1eb7t v\u00e0 ph\u1ee5c h\u00ecnh b\u1eb1ng implant \u1edf b\u1ec7nh nh\u00e2n PLS. Implant c\u00f3 th\u1ec3 gi\u1ed1ng nh\u01b0 m\u1ed9t r\u0103ng b\u1ecb c\u1ee9ng kh\u1edbp n\u1ebfu \u0111\u01b0\u1ee3c \u0111\u1eb7t tr\u01b0\u1edbc khi m\u1ecfm x\u01b0\u01a1ng \u1ed5 ng\u1eebng t\u0103ng tr\u01b0\u1edfng, v\u00e0 do \u0111\u00f3 n\u00f3 b\u1ecb ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf tr\u1ebb nh\u1ecf. \u0110i\u1ec1u tr\u1ecb ph\u1ee5c h\u00ecnh tr\u1edf n\u00ean kh\u00f3 kh\u0103n h\u01a1n \u1edf b\u1ec7nh nh\u00e2n b\u1ecb teo x\u01b0\u01a1ng h\u00e0m d\u01b0\u1edbi v\u00e0 x\u01b0\u01a1ng h\u00e0m tr\u00ean. C\u00f9ng t\u00ecm hi\u1ec3u t\u1ed5ng quan h\u1ed9i ch\u1ee9ng n\u00e0y v\u00e0 nh\u1eefng \u0111\u00e1p \u1ee9ng \u0111i\u1ec1u tr\u1ecb, ki\u1ec3m so\u00e1t tr\u00ean \u0111\u1ed1i t\u01b0\u1ee3ng b\u1ec7nh nh\u00e2n.\u00a0<\/strong><\/p>\n

\"Hoi-chung-Papillon-Lefevre\"<\/p>\n

1. T\u1ed5ng quan v\u1ec1 H\u1ed9i ch\u1ee9ng Papillon-Lef\u00e8vre (PLS) v\u00e0 qu\u00e1 tr\u00ecnh Implant tr\u00ean b\u1ec7nh nh\u00e2n<\/h2>\n

H\u1ed9i ch\u1ee9ng Papillon-Lef\u00e8vre (PLS) l\u00e0 m\u1ed9t b\u1ec7nh l\u00fd nghi\u00eam tr\u1ecdng, \u0111\u1eb7c tr\u01b0ng b\u1edfi s\u1ef1 ph\u00e1 h\u1ee7y nhanh ch\u00f3ng ph\u1ee9c h\u1ee3p x\u01b0\u01a1ng \u1ed5 r\u0103ng, \u1ea3nh h\u01b0\u1edfng l\u00ean c\u1ea3 r\u0103ng s\u1eefa l\u1eabn r\u0103ng v\u0129nh vi\u1ec5n. Nh\u1ed5 s\u1edbm c\u00e1c r\u0103ng v\u0129nh vi\u1ec5n v\u00e0 ph\u1ee5c h\u1ed3i b\u1eb1ng ph\u1ee5c h\u00ecnh \u0111\u01b0\u1ee3c xem l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p gi\u1ea3i quy\u1ebft trong t\u00ecnh hu\u1ed1ng n\u00e0y. M\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n c\u00f3 ti\u00ean l\u01b0\u1ee3ng r\u0103ng k\u00e9m do h\u1ea7u h\u1ebft c\u00e1c r\u0103ng \u0111\u1ec1u lung lay \u0111\u1ed9 III. Nha s\u0129 \u0111\u00f4i khi s\u1eed d\u1ee5ng c\u00e1c r\u0103ng c\u1ed1i l\u1edbn th\u1ee9 hai \u0111\u01b0\u1ee3c gi\u1eef l\u1ea1i \u0111\u1ec3 l\u00e0m r\u0103ng tr\u1ee5 \u0111\u1ed3ng th\u1eddi \u0111\u1ec3 duy tr\u00ec k\u00edch th\u01b0\u1edbc d\u1ecdc c\u1eafn kh\u1edbp.<\/p>\n

Kh\u00f4ng c\u00f3 nhi\u1ec1u b\u00e1o c\u00e1o ca m\u00f4 t\u1ea3 v\u1ec1 vi\u1ec7c \u0111\u1eb7t v\u00e0 ph\u1ee5c h\u00ecnh b\u1eb1ng implant \u1edf b\u1ec7nh nh\u00e2n PLS. Implant c\u00f3 th\u1ec3 gi\u1ed1ng nh\u01b0 m\u1ed9t r\u0103ng b\u1ecb c\u1ee9ng kh\u1edbp n\u1ebfu \u0111\u01b0\u1ee3c \u0111\u1eb7t tr\u01b0\u1edbc khi m\u1ecfm x\u01b0\u01a1ng \u1ed5 ng\u1eebng t\u0103ng tr\u01b0\u1edfng, v\u00e0 do \u0111\u00f3 n\u00f3 b\u1ecb ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf tr\u1ebb nh\u1ecf. \u0110i\u1ec1u tr\u1ecb ph\u1ee5c h\u00ecnh tr\u1edf n\u00ean kh\u00f3 kh\u0103n h\u01a1n \u1edf b\u1ec7nh nh\u00e2n b\u1ecb teo x\u01b0\u01a1ng h\u00e0m d\u01b0\u1edbi v\u00e0 x\u01b0\u01a1ng h\u00e0m tr\u00ean. T\u00ecnh tr\u1ea1ng n\u00e0y c\u00f3 th\u1ec3 c\u1ea7n th\u00eam c\u00e1c ph\u1eabu thu\u1eadt h\u1ed7 tr\u1ee3 kh\u00e1c, ch\u1eb3ng h\u1ea1n nh\u01b0 ph\u1eabu thu\u1eadt k\u00e9o gi\u00e3n x\u01b0\u01a1ng, ph\u1eabu thu\u1eadt gh\u00e9p x\u01b0\u01a1ng, v\u00e0 ph\u1eabu thu\u1eadt d\u1eddi d\u00e2y th\u1ea7n kinh, \u0111\u1ec3 c\u00f3 \u0111\u1ee7 x\u01b0\u01a1ng \u1edf x\u01b0\u01a1ng h\u00e0m b\u1ecb teo tr\u01b0\u1edbc khi \u0111\u1eb7t implant. M\u1ed9t v\u00e0i nghi\u00ean c\u1ee9u \u0111\u00e3 b\u00e1o c\u00e1o v\u1ec1 vi\u1ec7c \u0111\u1eb7t implant ng\u1eafn \u1edf x\u01b0\u01a1ng h\u00e0m d\u01b0\u1edbi b\u1ecb teo nghi\u00eam tr\u1ecdng b\u1edfi v\u00ec qu\u00e1 tr\u00ecnh ph\u1eabu thu\u1eadt c\u00f3 th\u1ec3 g\u00e2y g\u00e3y x\u01b0\u01a1ng. S\u1ef1 l\u00e0nh th\u01b0\u01a1ng b\u00ecnh th\u01b0\u1eddng \u0111\u00e3 \u0111\u01b0\u1ee3c ghi nh\u1eadn sau ph\u1eabu thu\u1eadt. Sau 1 n\u0103m theo d\u00f5i, t\u00ecnh tr\u1ea1ng l\u00e2m s\u00e0ng v\u00e0 X-quang c\u1ee7a c\u00e1c implant \u0111\u00e3 t\u00edch h\u1ee3p x\u01b0\u01a1ng c\u00f9ng v\u1edbi h\u00e0m gi\u1ea3 \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1, v\u00e0 kh\u00f4ng ghi nh\u1eadn \u0111\u01b0\u1ee3c d\u1ea5u hi\u1ec7u nhi\u1ec5m tr\u00f9ng ho\u1eb7c ti\u00eau x\u01b0\u01a1ng kh\u00f4ng mong mu\u1ed1n quanh implant.<\/p>\n

2. B\u1ec7nh nh\u00e2n m\u1eafc PLS c\u00f3 \u0111\u00e1p \u1ee9ng v\u1edbi \u0111i\u1ec1u tr\u1ecb nha chu th\u00f4ng th\u01b0\u1eddng kh\u00f4ng?<\/h2>\n

H\u1ed9i ch\u1ee9ng Papillon-Lef\u00e8vre (PLS) l\u00e0 m\u1ed9t b\u1ec7nh di truy\u1ec1n hi\u1ebfm g\u1eb7p, c\u00f3 t\u1ef7 l\u1ec7 1-4 ph\u1ea7n tri\u1ec7u. B\u1ec7nh n\u00e0y \u0111\u1eb7c tr\u01b0ng b\u1edfi t\u00ecnh tr\u1ea1ng t\u0103ng s\u1eebng h\u00f3a gan b\u00e0n tay-b\u00e0n ch\u00e2n v\u00e0 ph\u00e1 h\u1ee7y m\u00f4 nha chu nghi\u00eam tr\u1ecdng \u1ea3nh h\u01b0\u1edfng l\u00ean r\u0103ng s\u1eefa l\u1eabn r\u0103ng v\u0129nh vi\u1ec5n. PLS l\u00e0 do \u0111\u1ed9t bi\u1ebfn gen cathepsin C c\u00f3 ch\u1ee9c n\u0103ng ph\u00e2n h\u1ee7y protein v\u00e0 k\u00edch ho\u1ea1t ti\u1ec1n enzyme. C\u00e1c nghi\u00ean c\u1ee9u vi sinh v\u1ec1 m\u1eabu m\u1ea3ng b\u00e1m \u1edf b\u1ec7nh nh\u00e2n PLS cho th\u1ea5y c\u00f3 s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a c\u00e1c vi khu\u1ea9n k\u1ef5 kh\u00ed Gram \u00e2m, th\u01b0\u1eddng c\u00f3 Aggragatibacter actinomycetemcomitans.<\/p>\n

\u0110i\u1ec1u tr\u1ecb nha chu th\u00f4ng th\u01b0\u1eddng g\u1ea7n nh\u01b0 b\u1ecb th\u1ea5t b\u1ea1i \u1edf b\u1ec7nh nh\u00e2n PLS. \u0110i\u1ec1u tr\u1ecb th\u00f4ng th\u01b0\u1eddng s\u1ebd mang l\u1ea1i k\u1ebft qu\u1ea3 kh\u00f4ng th\u00e0nh c\u00f4ng, v\u00e0 cu\u1ed1i c\u00f9ng s\u1ebd d\u1eabn \u0111\u1ebfn m\u1ea5t r\u0103ng. M\u1ed9t ph\u01b0\u01a1ng ph\u00e1p kh\u00e1c \u0111\u01b0\u1ee3c \u0111\u1ec1 ngh\u1ecb l\u00e0 nh\u1ed5 t\u1ea5t c\u1ea3 c\u00e1c r\u0103ng \u0111\u00e3 m\u1ecdc \u1edf giai \u0111o\u1ea1n s\u1edbm v\u00e0 \u0111\u1ec3 tr\u1ed1ng r\u0103ng \u0111\u1ec3 ph\u00f2ng ng\u1eeba nhi\u1ec5m tr\u00f9ng cho c\u00e1c r\u0103ng ch\u01b0a m\u1ecdc. Ph\u01b0\u01a1ng ph\u00e1p n\u00e0y c\u00f3 th\u1ec3 \u0111em l\u1ea1i k\u1ebft qu\u1ea3 th\u00e0nh c\u00f4ng, nh\u01b0ng l\u1ea1i l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb qu\u00e1 m\u1ea1nh, nh\u1ea5t l\u00e0 \u1edf tr\u1ebb em ho\u1eb7c ng\u01b0\u1eddi tr\u1ebb, t\u1eeb \u0111\u00f3 g\u00e2y ra c\u00e1c h\u1eadu qu\u1ea3 l\u00ean r\u0103ng mi\u1ec7ng, g\u01b0\u01a1ng m\u1eb7t, v\u00e0 t\u00e2m l\u00fd. N\u00f3i chung, n\u00ean ch\u1edd \u0111\u1ebfn khi ho\u00e0n t\u1ea5t t\u0103ng tr\u01b0\u1edfng x\u01b0\u01a1ng.<\/p>\n

3. Ki\u1ec3m so\u00e1t b\u1ec7nh nh\u00e2n m\u1eafc PLS nh\u01b0 th\u1ebf n\u00e0o?<\/h2>\n

C\u00f3 m\u1ed9t v\u00e0i b\u1eb1ng ch\u1ee9ng cho th\u1ea5y, \u1edf m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n PLS, b\u1ec7nh nha chu c\u00f3 th\u1ec3 ng\u01b0ng ti\u1ebfn tri\u1ec3n b\u1eb1ng c\u00e1ch \u0111i\u1ec1u tr\u1ecb nha chu c\u01a1 h\u1ecdc k\u1ebft h\u1ee3p kh\u00e1ng sinh, nh\u1ed5 c\u00e1c r\u0103ng b\u1ecb b\u1ec7nh nha chu n\u1eb7ng, h\u01b0\u1edbng d\u1eabn v\u1ec7 sinh r\u0103ng mi\u1ec7ng, \u0111i\u1ec1u tr\u1ecb duy tr\u00ec c\u01b0\u1eddng \u0111\u1ed9 cao, theo d\u00f5i vi sinh v\u00e0 \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m A. actinomycetemcomitans.<\/p>\n

C\u00e1c ph\u01b0\u01a1ng ph\u00e1p ki\u1ec3m so\u00e1t b\u1ec7nh nh\u00e2n s\u1edbm:<\/p>\n

    \n
  • Ch\u1ea9n \u0111o\u00e1n s\u1edbm v\u00e0 \u0111i\u1ec1u tr\u1ecb ch\u1ed1ng nhi\u1ec5m khu\u1ea9n (c\u1ea1o v\u00f4i v\u00e0 x\u1eed l\u00fd m\u1eb7t ch\u00e2n r\u0103ng, k\u1ebft h\u1ee3p amoxicillin v\u00e0 metronidazole to\u00e0n th\u00e2n, c\u00f9ng v\u1edbi nh\u1ed5 c\u00e1c r\u0103ng b\u1ecb b\u1ec7nh nha chu n\u1eb7ng).<\/li>\n
  • \u1ee8c ch\u1ebf A. actinomycetemcomitans d\u01b0\u1edbi ng\u01b0\u1ee1ng ph\u00e1t hi\u1ec7n.<\/li>\n
  • \u0110i\u1ec1u tr\u1ecb duy tr\u00ec c\u01b0\u1eddng \u0111\u1ed9 cao.<\/li>\n<\/ul>\n

    C\u1ea5y gh\u00e9p nha khoa \u1edf b\u1ec7nh nh\u00e2n PLS l\u00e0 m\u1ed9t ph\u01b0\u01a1ng \u00e1n \u0111i\u1ec1u tr\u1ecb, nh\u01b0ng c\u1ea7n nh\u1edb r\u1eb1ng nh\u1eefng b\u1ec7nh nh\u00e2n n\u00e0y c\u00f3 nguy c\u01a1 vi\u00eam quanh implant v\u00e0 th\u1ea5t b\u1ea1i implant cao n\u1ebfu h\u1ecd kh\u00f4ng tu\u00e2n th\u1ee7 ph\u00e1c \u0111\u1ed9 ch\u0103m s\u00f3c duy tr\u00ec. N\u00f3i chung, nha s\u0129 v\u00e0 b\u1ec7nh nh\u00e2n PLS c\u1ea7n nh\u1edb r\u1eb1ng \u0111i\u1ec1u tr\u1ecb cho b\u1ec7nh nh\u00e2n PLS lu\u00f4n \u0111\u01b0\u1ee3c xem l\u00e0 c\u00f3 nguy c\u01a1 cao. C\u00f3 r\u1ea5t \u00edt tr\u01b0\u1eddng h\u1ee3p \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o, v\u00e0 do \u0111\u00f3, r\u1ea5t kh\u00f3 \u0111\u1ec3 ti\u00ean l\u01b0\u1ee3ng s\u1ef1 th\u00e0nh c\u00f4ng l\u00e2u d\u00e0i c\u1ee7a nh\u1eefng t\u00ecnh hu\u1ed1ng n\u00e0y.<\/p>\n

    Ngu\u1ed3n t\u00e0i li\u1ec7u: Clinical Cases in Implant Dentistry, First Edition – Published 2017 by John Wiley & Sons, Inc.<\/em><\/p>\n

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    2. Woo I, Brunner DP, Yamashita DD, Le BT. Dental implants in a young patient with Papillon-Lef\u00e8vre syndrome: a case report. Implant Dent 2003;12:140-144.<\/p>\n

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    4. Etoz OA, Ulu M, Kesim B. Treatment of patient with Papillon-Lef\u00e8vre syndrome with short dental implants: a case report. Implant Dent 2010;19:394-399.<\/p>\n

    5. Gorlin RJ, Sedano H, Anderson VE. The syndrome of palmar-plantar hyperkeratosis and premature periodontal destruction of the teeth. A clinical and genetic analysis of the Papillon-Lef\u00e8vre syndrome. J Pediatr 1964;65:895-906.<\/p>\n

    6. Hart TC, Hart PS, Bowden DW, et al. Mutations of the cathepsin C gene are responsible for Papillon-Lef\u00e8vre syndrome. J Med Genet 1999;36:881-887<\/p>\n

    7. Rao NV, Rao GV, Hoidal JR. Human dipeptidyl-peptidase 1. Gene characterization, localization, and expression. J Biol Chem 1997;272:10260-10265.<\/p>\n

    8. Albandar JM, Khattab R, Monem F, et al. The subgingival microbiota of Papillon-Lef\u00e8vre syndrome. J Periodontol 2012;83:902-908.<\/p>\n

    9. De Vree H, Steenackers K, de Boever JA. Periodontal treatment of rapid progressive periodontitis in 2 siblings with Papillon-Lef\u00e8vre syndrome: 15-years follow-up. J Clin Periodontol 2000;27:354-360.<\/p>\n

    10. Ishikawa I, Umeda M, Laosrisin N. Clinical, bacteriological, and immunological examination and the treatment process of two Papillon-Lef\u00e8vre syndrome patients. J Periodontol 1994;65:364-371.<\/p>\n

    11. Nickles K, Schacher B, Schuster G, et al. Evaluation of two siblings with Papillon-Lef\u00e8vre syndrome 5 years after treatment of periodontitis in primary and mixed dentition. J Periodontol 2011;82:1536-1547.<\/p>\n

    12. Nickles K, Schacher B, Ratka-Kruger P, et al. Long-term results after treatment of periodontitis in patients with Papillon-Lef\u00e8vre syndrome: success and failure. J Clin Periodontol 2013;40:789-798.<\/p>\n","protected":false},"excerpt":{"rendered":"

    H\u1ed9i ch\u1ee9ng Papillon-Lef\u00e8vre (PLS) l\u00e0 m\u1ed9t b\u1ec7nh l\u00fd nghi\u00eam tr\u1ecdng, \u0111\u1eb7c tr\u01b0ng b\u1edfi s\u1ef1 ph\u00e1 h\u1ee7y nhanh ch\u00f3ng ph\u1ee9c h\u1ee3p x\u01b0\u01a1ng \u1ed5 r\u0103ng, \u1ea3nh h\u01b0\u1edfng l\u00ean c\u1ea3 r\u0103ng s\u1eefa l\u1eabn r\u0103ng v\u0129nh vi\u1ec5n. Nh\u1ed5 s\u1edbm c\u00e1c r\u0103ng v\u0129nh vi\u1ec5n v\u00e0 ph\u1ee5c h\u1ed3i b\u1eb1ng ph\u1ee5c h\u00ecnh \u0111\u01b0\u1ee3c xem l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p gi\u1ea3i quy\u1ebft trong t\u00ecnh […]<\/p>\n","protected":false},"author":21,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[28,33],"tags":[],"yoast_head":"\nH\u1ed9i ch\u1ee9ng Papillon-Lef\u00e8vre (PLS) v\u00e0 Implant nha khoa. - Vinmec<\/title>\n<meta name=\"description\" content=\"C\u00f9ng t\u00ecm hi\u1ec3u t\u1ed5ng quan H\u1ed9i ch\u1ee9ng Papillon-Lef\u00e8vre n\u00e0y v\u00e0 nh\u1eefng \u0111\u00e1p \u1ee9ng \u0111i\u1ec1u tr\u1ecb, ki\u1ec3m so\u00e1t tr\u00ean \u0111\u1ed1i t\u01b0\u1ee3ng b\u1ec7nh nh\u00e2n.\u00a0\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"H\u1ed9i ch\u1ee9ng Papillon-Lef\u00e8vre (PLS) v\u00e0 Implant nha khoa. - 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