{"id":31780,"date":"2023-05-04T17:30:16","date_gmt":"2023-05-04T10:30:16","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=31780"},"modified":"2023-05-08T14:25:20","modified_gmt":"2023-05-08T07:25:20","slug":"vai-tro-gen-brca1-va-brca2-trong-ung-thu-vu","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/05\/04\/vai-tro-gen-brca1-va-brca2-trong-ung-thu-vu\/","title":{"rendered":"Vai tr\u00f2 gen BRCA1 v\u00e0 BRCA2 trong ung th\u01b0 v\u00fa"},"content":{"rendered":"

Gen BRCA1 v\u00e0 BRCA2 \u0111\u00f3ng vai tr\u00f2 quan tr\u1ecdng trong qu\u00e1 tr\u00ecnh ki\u1ec3m so\u00e1t, s\u1eeda ch\u1eefa DNA. Khi c\u00f3 \u0111\u1ed9t bi\u1ebfn tr\u00ean hai gen n\u00e0y x\u1ea3y ra, qu\u00e1 tr\u00ecnh ki\u1ec3m so\u00e1t b\u1ecb \u1ea3nh h\u01b0\u1edfng d\u1eabn \u0111\u1ebfn t\u00edch t\u1ee5 c\u00e1c l\u1ed7i tr\u00ean DNA v\u00e0 g\u00e2y ra c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 t\u0103ng tr\u01b0\u1edfng v\u00e0 ph\u00e1t tri\u1ec3n c\u1ee7a c\u00e1c t\u1ebf b\u00e0o \u1edf tuy\u1ebfn v\u00fa.<\/strong><\/p>\n

1. Gi\u1edbi thi\u1ec7u<\/h2>\n

Ung th\u01b0 v\u00fa l\u00e0 m\u1ed9t lo\u1ea1i ung th\u01b0 ph\u00e1t tri\u1ec3n t\u1eeb t\u1ebf b\u00e0o trong tuy\u1ebfn v\u00fa. \u0110\u00e2y l\u00e0 lo\u1ea1i ung th\u01b0 ph\u1ed5 bi\u1ebfn nh\u1ea5t \u1edf ph\u1ee5 n\u1eef v\u00e0 c\u00f3 th\u1ec3 x\u1ea3y ra \u1edf c\u1ea3 nam v\u00e0 n\u1eef.<\/p>\n

Gen BRCA1 n\u1eb1m tr\u00ean c\u00e1nh d\u00e0i c\u1ee7a nhi\u1ec5m s\u1eafc th\u1ec3 s\u1ed1 17 v\u00e0 m\u00e3 h\u00f3a m\u1ed9t protein v\u1edbi nhi\u1ec1u ch\u1ee9c n\u0103ng kh\u00e1c nhau, bao g\u1ed3m s\u1eeda ch\u1eefa DNA, \u0111i\u1ec1u khi\u1ec3n s\u1ef1 ph\u00e2n chia t\u1ebf b\u00e0o v\u00e0 gi\u00fap duy tr\u00ec c\u1ea5u tr\u00fac c\u1ee7a t\u1ebf b\u00e0o. Khi gen BRCA1 b\u1ecb \u0111\u1ed9t bi\u1ebfn, s\u1ef1 ph\u00e2n b\u00e0o v\u00e0 s\u1eeda ch\u1eefa DNA c\u00f3 th\u1ec3 b\u1ecb \u1ea3nh h\u01b0\u1edfng, d\u1eabn \u0111\u1ebfn t\u0103ng nguy c\u01a1 ph\u00e1t tri\u1ec3n ung th\u01b0 v\u00fa v\u00e0 ung th\u01b0 bu\u1ed3ng tr\u1ee9ng.<\/p>\n

Gen BRCA2 n\u1eb1m tr\u00ean c\u00e1nh d\u00e0i c\u1ee7a nhi\u1ec5m s\u1eafc th\u1ec3 s\u1ed1 13 v\u00e0 m\u00e3 h\u00f3a m\u1ed9t protein c\u00f3 ch\u1ee9c n\u0103ng s\u1eeda ch\u1eefa DNA. Khi gen BRCA2 b\u1ecb \u0111\u1ed9t bi\u1ebfn, s\u1ef1 ph\u00e2n b\u00e0o v\u00e0 s\u1eeda ch\u1eefa DNA c\u00f3 th\u1ec3 b\u1ecb \u1ea3nh h\u01b0\u1edfng, d\u1eabn \u0111\u1ebfn t\u0103ng nguy c\u01a1 ph\u00e1t tri\u1ec3n ung th\u01b0 v\u00fa v\u00e0 ung th\u01b0 bu\u1ed3ng tr\u1ee9ng.<\/p>\n

\"hinh-anh-minh-hoa-benh-nhan-ung-thu-vu\"
H\u00ecnh \u1ea3nh minh h\u1ecda b\u1ec7nh nh\u00e2n ung th\u01b0 v\u00fa<\/figcaption><\/figure>\n

2. Vai tr\u00f2 c\u1ee7a gen BRCA1 v\u00e0 BRCA2 trong s\u1ef1 ph\u00e1t tri\u1ec3n ung th\u01b0 v\u00fa<\/h2>\n

Gen BRCA1 m\u00e3 h\u00f3a m\u1ed9t protein c\u00f3 nhi\u1ec1u ch\u1ee9c n\u0103ng kh\u00e1c nhau. Protein BRCA1 \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn v\u1edbi vai tr\u00f2 quan tr\u1ecdng trong s\u1eeda ch\u1eefa DNA. N\u00f3 c\u00f3 th\u1ec3 li\u00ean k\u1ebft v\u1edbi c\u00e1c protein kh\u00e1c t\u1ea1o th\u00e0nh c\u00e1c c\u1ea5u tr\u00fac ph\u1ee9c t\u1ea1p \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 foci DNA, gi\u00fap t\u1eadp trung c\u00e1c protein s\u1eeda ch\u1eefa DNA v\u00e0o nh\u1eefng n\u01a1i c\u1ea7n thi\u1ebft tr\u00ean DNA. Protein BRCA1 c\u0169ng c\u00f3 kh\u1ea3 n\u0103ng \u0111i\u1ec1u khi\u1ec3n s\u1ef1 ph\u00e2n chia t\u1ebf b\u00e0o v\u00e0 duy tr\u00ec c\u1ea5u tr\u00fac c\u1ee7a t\u1ebf b\u00e0o.<\/p>\n

Gen BRCA2 c\u0169ng m\u00e3 h\u00f3a m\u1ed9t protein c\u00f3 ch\u1ee9c n\u0103ng s\u1eeda ch\u1eefa DNA. Protein BRCA2 l\u00e0m vi\u1ec7c nh\u01b0 m\u1ed9t ch\u1ea5t d\u1eabn xu\u1ea5t c\u1ee7a enzyme Rad51, gi\u00fap n\u00f3 k\u1ebft h\u1ee3p v\u1edbi DNA v\u00e0 h\u1ed7 tr\u1ee3 qu\u00e1 tr\u00ecnh s\u1eeda ch\u1eefa DNA. Protein BRCA2 c\u0169ng c\u00f3 kh\u1ea3 n\u0103ng t\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c protein kh\u00e1c \u0111\u1ec3 t\u1ea1o th\u00e0nh c\u00e1c c\u1ea5u tr\u00fac ph\u1ee9c t\u1ea1p, gi\u00fap t\u1eadp trung c\u00e1c protein s\u1eeda ch\u1eefa DNA v\u00e0o nh\u1eefng n\u01a1i c\u1ea7n thi\u1ebft tr\u00ean DNA.<\/p>\n

S\u1ef1 ph\u00e2n b\u00e0o v\u00e0 s\u1eeda ch\u1eefa DNA l\u00e0 qu\u00e1 tr\u00ecnh quan tr\u1ecdng trong duy tr\u00ec t\u00ednh to\u00e0n v\u1eb9n c\u1ee7a DNA v\u00e0 gi\u00fap ng\u0103n ng\u1eeba s\u1ef1 ph\u00e1t tri\u1ec3n c\u00e1c b\u1ec7nh ung th\u01b0.<\/p>\n

\u0110\u1ed9t bi\u1ebfn gen BRCA1 v\u00e0 BRCA2 \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn qu\u00e1 tr\u00ecnh ph\u00e2n b\u00e0o v\u00e0 s\u1eeda ch\u1eefa DNA. Hai gen n\u00e0y \u0111\u00f3ng vai tr\u00f2 quan tr\u1ecdng trong vi\u1ec7c ki\u1ec3m so\u00e1t qu\u00e1 tr\u00ecnh s\u1eeda ch\u1eefa DNA b\u1eb1ng c\u00e1ch gi\u00fap ph\u00e1t hi\u1ec7n v\u00e0 kh\u1eafc ph\u1ee5c nh\u1eefng t\u1ed5n th\u01b0\u01a1ng tr\u00ean DNA.<\/p>\n

Khi c\u00e1c \u0111\u1ed9t bi\u1ebfn x\u1ea3y ra tr\u00ean gen BRCA1 ho\u1eb7c BRCA2, qu\u00e1 tr\u00ecnh s\u1eeda ch\u1eefa DNA c\u00f3 th\u1ec3 b\u1ecb \u1ea3nh h\u01b0\u1edfng. \u0110i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn s\u1ef1 t\u00edch t\u1ee5 c\u1ee7a c\u00e1c l\u1ed7i tr\u00ean DNA, g\u00e2y ra nh\u1eefng h\u1eadu qu\u1ea3 nghi\u00eam tr\u1ecdng nh\u01b0 ung th\u01b0. Ngo\u00e0i ra, c\u00e1c \u0111\u1ed9t bi\u1ebfn n\u00e0y c\u00f2n c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m kh\u1ea3 n\u0103ng ph\u00e2n b\u00e0o c\u1ee7a t\u1ebf b\u00e0o, g\u00e2y ra c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 t\u0103ng tr\u01b0\u1edfng v\u00e0 ph\u00e1t tri\u1ec3n c\u1ee7a c\u00e1c t\u1ebf b\u00e0o.<\/p>\n

Nghi\u00ean c\u1ee9u \u0111\u00e3 ch\u1ec9 ra r\u1eb1ng vi\u1ec7c ph\u00e1t hi\u1ec7n s\u1edbm c\u00e1c \u0111\u1ed9t bi\u1ebfn tr\u00ean gen BRCA1 v\u00e0 BRCA2 c\u00f3 th\u1ec3 gi\u00fap trong vi\u1ec7c ph\u00f2ng ng\u1eeba v\u00e0 \u0111i\u1ec1u tr\u1ecb ung th\u01b0. Tuy nhi\u00ean, hi\u1ec3u r\u00f5 h\u01a1n v\u1ec1 c\u00e1ch \u0111\u1ed9t bi\u1ebfn n\u00e0y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn qu\u00e1 tr\u00ecnh ph\u00e2n b\u00e0o v\u00e0 s\u1eeda ch\u1eefa DNA v\u1eabn \u0111ang l\u00e0 ch\u1ee7 \u0111\u1ec1 nghi\u00ean c\u1ee9u \u0111\u1ea7y th\u00fa v\u1ecb c\u1ee7a c\u00e1c nh\u00e0 khoa h\u1ecdc.<\/p>\n

3. Li\u00ean quan gi\u1eefa \u0111\u1ed9t bi\u1ebfn gen BRCA1 v\u00e0 BRCA2 v\u00e0 ung th\u01b0 v\u00fa<\/h2>\n

\u0110\u1ed9t bi\u1ebfn gen BRCA1 v\u00e0 BRCA2 \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn l\u00e0 nh\u1eefng y\u1ebfu t\u1ed1 t\u0103ng nguy c\u01a1 m\u1eafc ung th\u01b0 v\u00fa. Nh\u1eefng ng\u01b0\u1eddi c\u00f3 \u0111\u1ed9t bi\u1ebfn tr\u00ean hai gen n\u00e0y c\u00f3 nguy c\u01a1 m\u1eafc ung th\u01b0 v\u00fa cao h\u01a1n g\u1ea5p nhi\u1ec1u l\u1ea7n so v\u1edbi ng\u01b0\u1eddi b\u00ecnh th\u01b0\u1eddng.<\/p>\n

BRCA1 v\u00e0 BRCA2 l\u00e0 hai gen ch\u1ecbu tr\u00e1ch nhi\u1ec7m trong vi\u1ec7c ki\u1ec3m so\u00e1t qu\u00e1 tr\u00ecnh s\u1eeda ch\u1eefa DNA. Khi c\u00e1c \u0111\u1ed9t bi\u1ebfn x\u1ea3y ra tr\u00ean hai gen n\u00e0y, qu\u00e1 tr\u00ecnh ki\u1ec3m so\u00e1t n\u00e0y b\u1ecb \u1ea3nh h\u01b0\u1edfng, d\u1eabn \u0111\u1ebfn t\u00edch t\u1ee5 c\u00e1c l\u1ed7i tr\u00ean DNA. Nh\u1eefng l\u1ed7i n\u00e0y c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a c\u00e1c kh\u1ed1i u \u00e1c t\u00ednh tr\u00ean v\u00fa.<\/p>\n

Ngo\u00e0i ra, c\u00e1c \u0111\u1ed9t bi\u1ebfn tr\u00ean BRCA1 v\u00e0 BRCA2 c\u0169ng c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 ho\u1ea1t \u0111\u1ed9ng c\u1ee7a c\u00e1c protein c\u00f3 li\u00ean quan \u0111\u1ebfn qu\u00e1 tr\u00ecnh s\u1eeda ch\u1eefa DNA v\u00e0 qu\u00e1 tr\u00ecnh ch\u1ed1ng oxy h\u00f3a, d\u1eabn \u0111\u1ebfn s\u1ef1 t\u00edch t\u1ee5 c\u00e1c l\u1ed7i tr\u00ean DNA v\u00e0 \u0111\u1ed9t bi\u1ebfn gen.<\/p>\n

Hi\u1ec3u r\u00f5 v\u1ec1 s\u1ef1 li\u00ean quan gi\u1eefa \u0111\u1ed9t bi\u1ebfn gen BRCA1 v\u00e0 BRCA2 v\u00e0 ung th\u01b0 v\u00fa \u0111\u00e3 gi\u00fap c\u00e1c nh\u00e0 khoa h\u1ecdc ph\u00e1t tri\u1ec3n c\u00e1c ph\u01b0\u01a1ng ph\u00e1p ph\u00f2ng ng\u1eeba v\u00e0 ch\u1ea9n \u0111o\u00e1n s\u1edbm ung th\u01b0 v\u00fa.<\/p>\n

4. C\u00e1c bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba v\u00e0 \u0111i\u1ec1u tr\u1ecb ung th\u01b0 v\u00fa li\u00ean quan \u0111\u1ebfn gen BRCA1 v\u00e0 BRCA2<\/h2>\n

C\u00e1c bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba v\u00e0 \u0111i\u1ec1u tr\u1ecb ung th\u01b0 v\u00fa li\u00ean quan \u0111\u1ebfn gen BRCA1 v\u00e0 BRCA2 \u0111ang \u0111\u01b0\u1ee3c quan t\u00e2m v\u00e0 nghi\u00ean c\u1ee9u r\u1ed9ng r\u00e3i trong c\u1ed9ng \u0111\u1ed3ng y t\u1ebf. \u0110\u1ed1i v\u1edbi nh\u1eefng ng\u01b0\u1eddi c\u00f3 \u0111\u1ed9t bi\u1ebfn tr\u00ean hai gen n\u00e0y, c\u00e1c bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba v\u00e0 \u0111i\u1ec1u tr\u1ecb c\u1ea7n \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng \u0111\u00fang c\u00e1ch v\u00e0 hi\u1ec7u qu\u1ea3 \u0111\u1ec3 gi\u1ea3m thi\u1ec3u nguy c\u01a1 m\u1eafc b\u1ec7nh.<\/p>\n

Ph\u01b0\u01a1ng ph\u00e1p ph\u00f2ng ng\u1eeba ung th\u01b0 v\u00fa li\u00ean quan \u0111\u1ebfn gen BRCA1 v\u00e0 BRCA2 bao g\u1ed3m vi\u1ec7c ti\u00ean \u0111o\u00e1n nguy c\u01a1 b\u1ec7nh v\u00e0 ph\u1eabu thu\u1eadt ph\u00f2ng ng\u1eeba. \u0110\u1ea7u ti\u00ean, c\u00e1c b\u00e1c s\u0129 c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng c\u00e1c x\u00e9t nghi\u1ec7m di truy\u1ec1n<\/a> \u0111\u1ec3 ph\u00e1t hi\u1ec7n c\u00e1c \u0111\u1ed9t bi\u1ebfn tr\u00ean hai gen n\u00e0y. N\u1ebfu nguy c\u01a1 m\u1eafc ung th\u01b0 v\u00fa cao, ph\u1eabu thu\u1eadt ph\u00f2ng ng\u1eeba c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n \u0111\u1ec3 lo\u1ea1i b\u1ecf tuy\u1ebfn v\u00fa ho\u1eb7c bu\u1ed3ng tr\u1ee9ng.<\/p>\n

\u0110\u1ed1i v\u1edbi nh\u1eefng ng\u01b0\u1eddi c\u00f3 k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m di truy\u1ec1n cho th\u1ea5y h\u1ecd c\u00f3 \u0111\u1ed9t bi\u1ebfn tr\u00ean hai gen BRCA1 v\u00e0 BRCA2, vi\u1ec7c theo d\u00f5i s\u1ee9c kh\u1ecfe \u0111\u1ecbnh k\u1ef3 v\u00e0 th\u1ef1c hi\u1ec7n c\u00e1c k\u1ef9 thu\u1eadt ch\u1ea9n \u0111o\u00e1n s\u1edbm ung th\u01b0 v\u00fa l\u00e0 r\u1ea5t quan tr\u1ecdng. C\u00e1c b\u00e1c s\u0129 c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng c\u00e1c k\u1ef9 thu\u1eadt ch\u1ee5p c\u1ed9ng h\u01b0\u1edfng t\u1eeb (MRI) v\u00e0 si\u00eau \u00e2m \u0111\u1ec3 theo d\u00f5i s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a kh\u1ed1i u tr\u00ean v\u00fa.<\/p>\n

Ngo\u00e0i ra, c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ung th\u01b0 v\u00fa li\u00ean quan \u0111\u1ebfn gen BRCA1 v\u00e0 BRCA2 bao g\u1ed3m ph\u1eabu thu\u1eadt, \u0111i\u1ec1u tr\u1ecb b\u1eb1ng tia X v\u00e0 h\u00f3a tr\u1ecb. \u0110\u1ed1i v\u1edbi nh\u1eefng ng\u01b0\u1eddi c\u00f3 \u0111\u1ed9t bi\u1ebfn tr\u00ean hai gen n\u00e0y v\u00e0 m\u1eafc ung th\u01b0 v\u00fa, vi\u1ec7c ti\u1ebfn h\u00e0nh ph\u1eabu thu\u1eadt lo\u1ea1i b\u1ecf kh\u1ed1i u v\u00e0 c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 l\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb hi\u1ec7u qu\u1ea3. \u0110i\u1ec1u tr\u1ecb b\u1eb1ng tia X v\u00e0 h\u00f3a tr\u1ecb c\u0169ng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 gi\u1ea3m thi\u1ec3u nguy c\u01a1 t\u00e1i ph\u00e1t v\u00e0 ng\u0103n ng\u1eeba s\u1ef1 lan r\u1ed9ng c\u1ee7a kh\u1ed1i u.<\/p>\n

5. K\u1ebft lu\u1eadn<\/h2>\n

S\u1ef1 ph\u00e1t tri\u1ec3n ung th\u01b0 v\u00fa li\u00ean quan \u0111\u1ebfn gen BRCA1 v\u00e0 BRCA2 \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh r\u00f5 r\u00e0ng trong nhi\u1ec1u nghi\u00ean c\u1ee9u khoa h\u1ecdc. Nh\u1eefng ng\u01b0\u1eddi c\u00f3 \u0111\u1ed9t bi\u1ebfn tr\u00ean hai gen n\u00e0y c\u00f3 nguy c\u01a1 m\u1eafc ung th\u01b0 v\u00fa cao h\u01a1n g\u1ea5p nhi\u1ec1u l\u1ea7n so v\u1edbi ng\u01b0\u1eddi b\u00ecnh th\u01b0\u1eddng. Ngo\u00e0i ra, nh\u1eefng ng\u01b0\u1eddi n\u00e0y c\u0169ng c\u00f3 nguy c\u01a1 m\u1eafc ung th\u01b0 v\u00fa \u1edf \u0111\u1ed9 tu\u1ed5i tr\u1ebb h\u01a1n so v\u1edbi nh\u1eefng ng\u01b0\u1eddi kh\u00f4ng c\u00f3 \u0111\u1ed9t bi\u1ebfn tr\u00ean hai gen n\u00e0y. Vi\u1ec7c ti\u00ean \u0111o\u00e1n nguy c\u01a1 m\u1eafc ung th\u01b0 v\u00fa v\u00e0 ph\u1eabu thu\u1eadt ph\u00f2ng ng\u1eeba c\u00f3 th\u1ec3 gi\u00fap gi\u1ea3m thi\u1ec3u nguy c\u01a1 m\u1eafc b\u1ec7nh v\u00e0 t\u0103ng c\u01a1 h\u1ed9i \u0111i\u1ec1u tr\u1ecb t\u1ed1t h\u01a1n cho b\u1ec7nh nh\u00e2n.<\/p>\n","protected":false},"excerpt":{"rendered":"

Gen BRCA1 v\u00e0 BRCA2 \u0111\u00f3ng vai tr\u00f2 quan tr\u1ecdng trong qu\u00e1 tr\u00ecnh ki\u1ec3m so\u00e1t, s\u1eeda ch\u1eefa DNA. Khi c\u00f3 \u0111\u1ed9t bi\u1ebfn tr\u00ean hai gen n\u00e0y x\u1ea3y ra, qu\u00e1 tr\u00ecnh ki\u1ec3m so\u00e1t b\u1ecb \u1ea3nh h\u01b0\u1edfng d\u1eabn \u0111\u1ebfn t\u00edch t\u1ee5 c\u00e1c l\u1ed7i tr\u00ean DNA v\u00e0 g\u00e2y ra c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 t\u0103ng tr\u01b0\u1edfng v\u00e0 ph\u00e1t tri\u1ec3n c\u1ee7a […]<\/p>\n","protected":false},"author":70,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[6,33],"tags":[],"yoast_head":"\nVai tr\u00f2 gen BRCA1 v\u00e0 BRCA2 trong ung th\u01b0 v\u00fa - Vinmec<\/title>\n<meta name=\"description\" content=\"\u0110\u1ed9t bi\u1ebfn gen BRCA1 v\u00e0 BRCA2 \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn qu\u00e1 tr\u00ecnh ph\u00e2n b\u00e0o v\u00e0 s\u1eeda ch\u1eefa DNA\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Vai tr\u00f2 gen BRCA1 v\u00e0 BRCA2 trong ung th\u01b0 v\u00fa - 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