{"id":31746,"date":"2023-06-22T15:05:21","date_gmt":"2023-06-22T08:05:21","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=31746"},"modified":"2023-06-22T15:05:21","modified_gmt":"2023-06-22T08:05:21","slug":"tac-dung-ngan-ngua-tai-phat-nhiem-trung-c-difficile-cua-vowst","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/06\/22\/tac-dung-ngan-ngua-tai-phat-nhiem-trung-c-difficile-cua-vowst\/","title":{"rendered":"T\u00e1c d\u1ee5ng ng\u0103n ng\u1eeba t\u00e1i ph\u00e1t nhi\u1ec5m tr\u00f9ng C. difficile c\u1ee7a Vowst"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y, ch\u00fang ta s\u1ebd t\u00ecm hi\u1ec3u v\u1ec1 s\u1ea3n ph\u1ea9m Vowst v\u00e0 t\u00e1c d\u1ee5ng m\u1edbi trong vi\u1ec7c ng\u0103n ng\u1eeba t\u00e1i ph\u00e1t nhi\u1ec5m tr\u00f9ng Clostridium difficile (C. difficile) (vi\u1ebft sapo nh\u01b0 n\u00e0y \u1ed5n ko Nhi, t\u1ea1i b\u1eeda nghe c n\u00f3i sapo c\u00f3 t\u1ed5ng quan n\u1ed9i dung m\u00e0 m\u00ecnh n\u00f3i…)<\/strong><\/p>\n

1.Gi\u1edbi thi\u1ec7u v\u1ec1 Clostridium difficile v\u00e0 v\u1ea5n \u0111\u1ec1 t\u00e1i ph\u00e1t nhi\u1ec5m tr\u00f9ng<\/strong><\/h2>\n

1.1 T\u1ed5ng quan v\u1ec1 Clostridium difficile v\u00e0 t\u00e1c h\u1ea1i \u0111\u1ed1i v\u1edbi s\u1ee9c kh\u1ecfe con ng\u01b0\u1eddi\u00a0<\/span><\/h3>\n

Clostridium difficile (c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 C.diff ho\u1eb7c C.difficile) thu\u1ed9c h\u1ecd Clostridiaceae l\u00e0 m\u1ed9t lo\u1ea1i vi khu\u1ea9n k\u1ef5 kh\u00ed v\u00e0 sinh b\u00e0o t\u1eed. Vi khu\u1ea9n l\u00e0 m\u1ed9t lo\u1ea1i t\u1ebf b\u00e0o sinh d\u01b0\u1ee1ng h\u00ecnh que, \u0111a h\u00ecnh, x\u1ebfp th\u00e0nh t\u1eebng c\u1eb7p ho\u1eb7c chu\u1ed7i ng\u1eafn v\u00e0 c\u00f3 ch\u1ee9a 2 lo\u1ea1i \u0111\u1ed9c t\u1ed1 Enterotoxin A v\u00e0 Cytotoxin B g\u00e2y \u0111\u1ed9c tr\u00ean c\u01a1 th\u1ec3 v\u1eadt ch\u1ee7 b\u1eb1ng c\u00e1ch l\u00e0m gi\u00e1n \u0111o\u1ea1n qu\u00e1 tr\u00ecnh truy\u1ec1n t\u00edn hi\u1ec7u gi\u1eefa c\u00e1c t\u1ebf b\u00e0o. C.difficile l\u00e0 nguy\u00ean nh\u00e2n ch\u00ednh g\u00e2y ti\u00eau ch\u1ea3y v\u00e0 vi\u00eam \u0111\u1ea1i tr\u00e0ng (vi\u00eam ru\u1ed9t k\u1ebft) do kh\u00e1ng sinh b\u1ec7nh vi\u1ec7n. \u01af\u1edbc t\u00ednh lo\u00e0i vi khu\u1ea9n n\u00e0y g\u00e2y ra g\u1ea7n n\u1eeda tri\u1ec7u ca nhi\u1ec5m tr\u00f9ng \u1edf Hoa K\u1ef3 m\u1ed7i n\u0103m. Kho\u1ea3ng 1 trong 6 b\u1ec7nh nh\u00e2n nhi\u1ec5m C. difficile s\u1ebd nhi\u1ec5m l\u1ea1i trong 2-8 tu\u1ea7n ti\u1ebfp theo. C\u1ee5 th\u1ec3, c\u1ee9 11 ng\u01b0\u1eddi tr\u00ean 65 tu\u1ed5i th\u00ec c\u00f3 m\u1ed9t ng\u01b0\u1eddi \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n nhi\u1ec5m C. difficile li\u00ean quan \u0111\u1ebfn tr\u01b0\u1eddng h\u1ee3p n\u1eb7ng s\u1ebd t\u1eed vong trong v\u00f2ng 1 th\u00e1ng.<\/span><\/p>\n

C\u00e1c y\u1ebfu t\u1ed1 r\u1ee7i ro l\u00e0m t\u0103ng nguy c\u01a1 nhi\u1ec5m C.difficile \u1edf c\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng: (1) tr\u00ean 65 tu\u1ed5i, (2) n\u1eb1m b\u1ec7nh vi\u1ec7n ho\u1eb7c vi\u1ec7n d\u01b0\u1ee1ng l\u00e3o trong th\u1eddi gian g\u1ea7n \u0111\u00e2y, (3) h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch suy y\u1ebfu (ng\u01b0\u1eddi nhi\u1ec5m HIV \/ AIDS, ung th\u01b0, b\u1ec7nh nh\u00e2n c\u1ea5y gh\u00e9p n\u1ed9i t\u1ea1ng d\u00f9ng thu\u1ed1c \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch), (4) b\u1ecb nhi\u1ec5m C.difficile tr\u01b0\u1edbc \u0111\u00f3 ho\u1eb7c \u0111\u00e3 ti\u1ebfp x\u00fac v\u1edbi vi khu\u1ea9n<\/span><\/p>\n

C\u00e1c tri\u1ec7u ch\u1ee9ng ph\u1ed5 bi\u1ebfn c\u1ee7a nhi\u1ec5m tr\u00f9ng C. difficile ti\u1ebfn tri\u1ec3n trong v\u00f2ng v\u00e0i ng\u00e0y sau khi b\u1eaft \u0111\u1ea7u d\u00f9ng thu\u1ed1c kh\u00e1ng sinh: ti\u00eau ch\u1ea3y, s\u1ed1t, \u0111au b\u1ee5ng ho\u1eb7c \u0111au, m\u1ea5t c\u1ea3m gi\u00e1c \u0103n ngon, bu\u1ed3n n\u00f4n\u00a0<\/span><\/p>\n

C\u00e1c b\u1ec7nh nh\u00e2n b\u1ecb nhi\u1ec5m C.difficile c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb t\u1ea1i nh\u00e0 ho\u1eb7c c\u1ea7n nh\u1eadp vi\u1ec7n trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb. Nhi\u1ec5m tr\u00f9ng C. difficile<\/a> \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng c\u00e1ch ng\u1eebng s\u1eed d\u1ee5ng c\u00e1c lo\u1ea1i kh\u00e1ng sinh ho\u1eb7c d\u00f9ng m\u1ed9t \u0111\u1ee3t \u0111i\u1ec1u tr\u1ecb lo\u1ea1i kh\u00e1ng sinh kh\u00e1c trong 10 ng\u00e0y. C\u00e1c tri\u1ec7u ch\u1ee9ng s\u1ebd c\u1ea3i thi\u1ec7n v\u00e0i ng\u00e0y sau khi b\u1eaft \u0111\u1ea7u \u0111\u1ee3t kh\u00e1ng sinh m\u1edbi. Nh\u01b0ng c\u00f3 th\u1ec3 m\u1ea5t t\u1eeb \u200b\u200b1 \u0111\u1ebfn 2 tu\u1ea7n tr\u01b0\u1edbc khi h\u1ebft nhi\u1ec5m tr\u00f9ng ho\u00e0n to\u00e0n. N\u1ebfu c\u00e1c tri\u1ec7u ch\u1ee9ng tr\u1edf l\u1ea1i, c\u1ea7n ph\u1ea3i ti\u1ebfn h\u00e0nh \u0111i\u1ec1u tr\u1ecb l\u1ea1i.\u00a0 N\u1ebfu nhi\u1ec5m tr\u00f9ng C.difficile t\u00e1i ph\u00e1t 2 l\u1ea7n tr\u1edf l\u00ean, b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111\u1ec1 ngh\u1ecb c\u1ea5y gh\u00e9p h\u1ec7 vi sinh v\u1eadt trong ph\u00e2n, vi khu\u1ea9n t\u1eeb ph\u00e2n c\u1ee7a ng\u01b0\u1eddi kh\u1ecfe m\u1ea1nh \u0111\u01b0\u1ee3c \u0111\u01b0a v\u00e0o ru\u1ed9t \u0111\u1ec3 gi\u00fap ng\u0103n ch\u1eb7n nhi\u1ec5m tr\u00f9ng\u00a0<\/span><\/p>\n

1.2 Nguy\u00ean nh\u00e2n d\u1eabn \u0111\u1ebfn t\u00e1i ph\u00e1t nhi\u1ec5m tr\u00f9ng C.difficile\u00a0<\/span><\/h3>\n
\"T\u00e1i
T\u00e1i ph\u00e1t nhi\u1ec5m tr\u00f9ng Clostridium difficile<\/figcaption><\/figure>\n

T\u00e1i ph\u00e1t nhi\u1ec5m tr\u00f9ng C. difficile x\u1ea3y ra khi b\u1ec7nh nh\u00e2n \u0111\u00e3 h\u1ed3i ph\u1ee5c v\u00e0 xu\u1ea5t vi\u1ec7n nh\u01b0ng sau \u0111\u00f3 c\u00e1c tri\u1ec7u ch\u1ee9ng l\u1ea1i xu\u1ea5t hi\u1ec7n l\u1ea7n n\u1eefa. C\u00e1c nguy\u00ean nh\u00e2n d\u1eabn \u0111\u1ebfn t\u00e1i ph\u00e1t nhi\u1ec5m tr\u00f9ng C. difficile bao g\u1ed3m:<\/span><\/p>\n

    \n
  • Kh\u00f4ng ti\u00eau di\u1ec7t h\u1ebft vi khu\u1ea9n: Khi s\u1eed d\u1ee5ng kh\u00e1ng sinh, m\u1ed9t s\u1ed1 vi khu\u1ea9n C. difficile c\u00f3 th\u1ec3 s\u1ed1ng s\u00f3t v\u00e0 ph\u00e1t tri\u1ec3n tr\u1edf l\u1ea1i sau khi kh\u00e1ng sinh \u0111\u01b0\u1ee3c ng\u1eebng s\u1eed d\u1ee5ng. \u0110i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 x\u1ea3y ra khi li\u1ec1u kh\u00e1ng sinh kh\u00f4ng \u0111\u1ee7 ho\u1eb7c th\u1eddi gian s\u1eed d\u1ee5ng kh\u00f4ng \u0111\u1ee7 \u0111\u1ec3 ti\u00eau di\u1ec7t h\u1ebft vi khu\u1ea9n.<\/span><\/li>\n
  • S\u1eed d\u1ee5ng kh\u00e1ng sinh li\u00ean t\u1ee5c: S\u1eed d\u1ee5ng kh\u00e1ng sinh li\u00ean t\u1ee5c trong m\u1ed9t kho\u1ea3ng th\u1eddi gian d\u00e0i c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m s\u1ef1 \u0111a d\u1ea1ng c\u1ee7a h\u1ec7 vi sinh v\u1eadt \u0111\u01b0\u1eddng ru\u1ed9t v\u00e0 t\u1ea1o \u0111i\u1ec1u ki\u1ec7n thu\u1eadn l\u1ee3i cho s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a C. difficile.<\/span><\/li>\n
  • S\u1eed d\u1ee5ng c\u00e1c lo\u1ea1i kh\u00e1ng sinh \u0111\u1eb7c bi\u1ec7t: M\u1ed9t s\u1ed1 lo\u1ea1i kh\u00e1ng sinh \u0111\u1eb7c bi\u1ec7t nh\u01b0 Clindamycin, Ceftriaxone v\u00e0 Fluoroquinolones c\u00f3 th\u1ec3 g\u00e2y ra t\u00e1c d\u1ee5ng ph\u1ee5 v\u00e0 l\u00e0m t\u0103ng nguy c\u01a1 nhi\u1ec5m tr\u00f9ng C. difficile.<\/span><\/li>\n
  • S\u1eed d\u1ee5ng thu\u1ed1c kh\u00e1ng acid d\u1ea1 d\u00e0y: M\u1ed9t s\u1ed1 lo\u1ea1i thu\u1ed1c kh\u00e1ng acid d\u1ea1 d\u00e0y nh\u01b0 Omeprazole, Lansoprazole v\u00e0 Esomeprazole c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m s\u1ef1 \u0111a d\u1ea1ng c\u1ee7a h\u1ec7 vi sinh v\u1eadt \u0111\u01b0\u1eddng ru\u1ed9t v\u00e0 t\u1ea1o \u0111i\u1ec1u ki\u1ec7n thu\u1eadn l\u1ee3i cho s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a C. difficile.<\/span><\/li>\n
  • B\u1ec7nh nh\u00e2n c\u00f3 y\u1ebfu t\u1ed1 nguy c\u01a1: C\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng b\u1ec7nh nh\u00e2n c\u00f3 y\u1ebfu t\u1ed1 nguy c\u01a1 nh\u01b0 tu\u1ed5i cao, b\u1ec7nh gan, b\u1ec7nh th\u1eadn, b\u1ec7nh l\u00fd ti\u00eau h\u00f3a, v\u00e0 h\u1ec7 mi\u1ec5n d\u1ecbch y\u1ebfu c\u00f3 nguy c\u01a1 cao h\u01a1n b\u1ecb t\u00e1i ph\u00e1t nhi\u1ec5m tr\u00f9ng C. difficile.<\/span><\/li>\n
  • M\u00f4i tr\u01b0\u1eddng y t\u1ebf: M\u00f4i tr\u01b0\u1eddng y t\u1ebf nh\u01b0 b\u1ec7nh vi\u1ec7n, nh\u00e0 d\u01b0\u1ee1ng l\u00e3o v\u00e0 tr\u1ea1i t\u00f9 c\u00f3 nguy c\u01a1 cao h\u01a1n cho t\u00e1i ph\u00e1t nhi\u1ec5m tr\u00f9ng C. difficile do s\u1ef1 l\u00e2y lan c\u1ee7a vi khu\u1ea9n trong m\u00f4i tr\u01b0\u1eddng n\u00e0y.<\/span><\/li>\n<\/ul>\n

    2.Th\u00f4ng tin v\u1ec1 thu\u1ed1c Vowst\u00a0<\/strong><\/h2>\n

    2.1 Qu\u00e1 tr\u00ecnh ph\u00ea duy\u1ec7t thu\u1ed1c Vowst<\/span><\/h3>\n

    V\u00e0o th\u00e1ng 4 n\u0103m 2023, C\u1ee5c Qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m Hoa K\u1ef3 (FDA) \u0111\u00e3 ph\u00ea duy\u1ec7t Vowst, s\u1ea3n ph\u1ea9m vi sinh v\u1eadt trong ph\u00e2n \u0111\u1ea7u ti\u00ean \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng \u0111\u1ec3 ng\u0103n ng\u1eeba t\u00e1i ph\u00e1t nhi\u1ec5m tr\u00f9ng Clostridioides difficile (C. difficile) (CDI) \u1edf nh\u1eefng ng\u01b0\u1eddi t\u1eeb 18 tu\u1ed5i tr\u1edf l\u00ean, sau khi \u0111i\u1ec1u tr\u1ecb b\u1eb1ng kh\u00e1ng sinh cho CDI t\u00e1i ph\u00e1t. S\u1ef1 an to\u00e0n c\u1ee7a Vowst \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 trong m\u1ed9t nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng ng\u1eabu nhi\u00ean, m\u00f9 \u0111\u00f4i, ki\u1ec3m so\u00e1t gi\u1ea3 d\u01b0\u1ee3c v\u00e0 m\u1ed9t nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng nh\u00e3n m\u1edf \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n \u1edf Hoa K\u1ef3 v\u00e0 Canada. Nh\u1eefng ng\u01b0\u1eddi tham gia b\u1ecb CDI t\u00e1i ph\u00e1t, \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb sau kh\u00e1ng sinh t\u1eeb 48 \u0111\u1ebfn 96 gi\u1edd v\u00e0 c\u00e1c tri\u1ec7u ch\u1ee9ng \u0111\u00e3 \u0111\u01b0\u1ee3c ki\u1ec3m so\u00e1t. H\u01a1n n\u1eefa, hi\u1ec7u qu\u1ea3 c\u1ee7a Vowst \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 trong nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng ng\u1eabu nhi\u00ean, c\u00f3 \u0111\u1ed1i ch\u1ee9ng v\u1edbi gi\u1ea3 d\u01b0\u1ee3c, trong \u0111\u00f3 89 ng\u01b0\u1eddi tham gia d\u00f9ng Vowst v\u00e0 93 ng\u01b0\u1eddi tham gia d\u00f9ng gi\u1ea3 d\u01b0\u1ee3c. K\u1ebft qu\u1ea3 sau 8 tu\u1ea7n sau khi \u0111i\u1ec1u tr\u1ecb, t\u00e1i ph\u00e1t CDI \u1edf nh\u1eefng ng\u01b0\u1eddi tham gia \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Vowst th\u1ea5p h\u01a1n so v\u1edbi nh\u1eefng ng\u01b0\u1eddi tham gia \u0111i\u1ec1u tr\u1ecb b\u1eb1ng gi\u1ea3 d\u01b0\u1ee3c (12,4% so v\u1edbi 39,8%)<\/span><\/p>\n

    \"Vowst\"
    Vowst<\/figcaption><\/figure>\n

    2.2 C\u1eadp nh\u1eadt th\u00f4ng tin v\u1ec1 thu\u1ed1c Vowst<\/span><\/h3>\n

    Vowst l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb b\u1eb1ng h\u1ec7 vi sinh v\u1eadt \u0111\u01b0\u1eddng u\u1ed1ng bao g\u1ed3m m\u1ed9t t\u1eadp h\u1ee3p c\u00e1c b\u00e0o t\u1eed Firmicutes c\u00f3 \u0111\u1ed9 tinh khi\u1ebft cao, th\u01b0\u1eddng s\u1ed1ng trong m\u1ed9t h\u1ec7 vi sinh v\u1eadt kh\u1ecfe m\u1ea1nh. Vowst ch\u1ee9a vi khu\u1ea9n s\u1ed1ng v\u00e0 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t t\u1eeb \u200b\u200bph\u00e2n ng\u01b0\u1eddi \u0111\u1ea1t \u0111\u1ee7 \u0111i\u1ec1u ki\u1ec7n. Vowst \u0111\u01b0\u1ee3c cho l\u00e0 c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m gi\u1ea3m s\u1ef1 t\u00e1i ph\u00e1t c\u1ee7a CDI b\u1eb1ng c\u00e1ch \u0111i\u1ec1u ch\u1ec9nh h\u1ec7 vi sinh v\u1eadt b\u1ecb ph\u00e1 v\u1ee1 sang tr\u1ea1ng th\u00e1i ch\u1ed1ng l\u1ea1i s\u1ef1 x\u00e2m nh\u1eadp v\u00e0 ph\u00e1t tri\u1ec3n c\u1ee7a C. difficile<\/span><\/p>\n

    D\u1ea1ng b\u00e0o ch\u1ebf c\u1ee7a thu\u1ed1c vi\u00ean nang v\u00e0 \u0111\u01b0\u1ee3c u\u1ed1ng m\u1ed9t l\u1ea7n m\u1ed7i ng\u00e0y khi b\u1ee5ng \u0111\u00f3i trong th\u1eddi gian 3 ng\u00e0y li\u00ean ti\u1ebfp. \u0110i\u1ec1u tr\u1ecb b\u1eb1ng kh\u00e1ng sinh \u0111\u1ed1i v\u1edbi CDI t\u00e1i ph\u00e1t n\u00ean \u0111\u01b0\u1ee3c ho\u00e0n th\u00e0nh t\u1eeb 2 \u0111\u1ebfn 4 ng\u00e0y tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Vowst<\/span><\/p>\n

    C\u00e1c ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i th\u01b0\u1eddng g\u1eb7p khi s\u1eed d\u1ee5ng thu\u1ed1c bao g\u1ed3m \u0111\u1ea7y b\u1ee5ng, m\u1ec7t m\u1ecfi, t\u00e1o b\u00f3n, \u1edbn l\u1ea1nh v\u00e0 ti\u00eau ch\u1ea3y<\/span><\/p>\n

    C\u00e1c c\u1ea3nh b\u00e1o v\u00e0 bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba li\u00ean quan \u0111\u1ebfn Vowst bao g\u1ed3m: nguy c\u01a1 truy\u1ec1n c\u00e1c t\u00e1c nh\u00e2n truy\u1ec1n nhi\u1ec5m v\u00e0 kh\u1ea3 n\u0103ng g\u00e2y d\u1ecb \u1ee9ng th\u1ef1c ph\u1ea9m<\/span><\/p>\n

    Vowst kh\u00f4ng n\u00ean u\u1ed1ng c\u00f9ng l\u00fac v\u1edbi kh\u00e1ng sinh v\u00ec c\u00f3 th\u1ec3 c\u1ea3n tr\u1edf vi khu\u1ea9n s\u1ed1ng c\u00f3 trong thu\u1ed1c<\/p>\n

    3.K\u1ebft lu\u1eadn\u00a0<\/strong><\/h2>\n

    T\u00f3m l\u1ea1i, nhi\u1ec5m tr\u00f9ng C. difficile l\u00e0 m\u1ed9t v\u1ea5n \u0111\u1ec1 s\u1ee9c kh\u1ecfe nghi\u00eam tr\u1ecdng v\u00e0 c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c bi\u1ebfn ch\u1ee9ng nguy hi\u1ec3m cho b\u1ec7nh nh\u00e2n. Trong nh\u1eefng n\u0103m g\u1ea7n \u0111\u00e2y, nhi\u1ec1u nghi\u00ean c\u1ee9u \u0111\u00e3 t\u00ecm c\u00e1ch gi\u1ea3i quy\u1ebft v\u1ea5n \u0111\u1ec1 n\u00e0y v\u00e0 m\u1ed9t trong nh\u1eefng ph\u01b0\u01a1ng ph\u00e1p ti\u1ec1m n\u0103ng l\u00e0 s\u1eed d\u1ee5ng s\u1ea3n ph\u1ea9m Vowst. V\u00e0 cho \u0111\u1ebfn nay, Vowst \u0111\u01b0\u1ee3c ch\u1ea5p thu\u1eadn d\u1ef1a tr\u00ean c\u00e1c b\u1eb1ng ch\u1ee9ng \u0111\u1ec3 ch\u1ee9ng minh l\u00e0 an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 trong c\u00e1c nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng v\u00e0 c\u00f3 th\u1ec3 l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p m\u1edbi \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb v\u00e0 ph\u00f2ng ng\u1eeba nhi\u1ec5m tr\u00f9ng C. difficile.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

    Trong b\u00e0i vi\u1ebft n\u00e0y, ch\u00fang ta s\u1ebd t\u00ecm hi\u1ec3u v\u1ec1 s\u1ea3n ph\u1ea9m Vowst v\u00e0 t\u00e1c d\u1ee5ng m\u1edbi trong vi\u1ec7c ng\u0103n ng\u1eeba t\u00e1i ph\u00e1t nhi\u1ec5m tr\u00f9ng Clostridium difficile (C. difficile) (vi\u1ebft sapo nh\u01b0 n\u00e0y \u1ed5n ko Nhi, t\u1ea1i b\u1eeda nghe c n\u00f3i sapo c\u00f3 t\u1ed5ng quan n\u1ed9i dung m\u00e0 m\u00ecnh n\u00f3i…) 1.Gi\u1edbi thi\u1ec7u v\u1ec1 Clostridium difficile […]<\/p>\n","protected":false},"author":54,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[12],"tags":[],"yoast_head":"\nT\u00e1c d\u1ee5ng ng\u0103n ng\u1eeba t\u00e1i ph\u00e1t nhi\u1ec5m tr\u00f9ng C. difficile c\u1ee7a Vowst<\/title>\n<meta name=\"description\" content=\"Vowst l\u00e0 lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u1edf ng\u01b0\u1eddi l\u1edbn \u0111\u1ec3 ng\u0103n ng\u1eeba nhi\u1ec5m tr\u00f9ng CDI 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