{"id":31530,"date":"2023-05-04T06:40:05","date_gmt":"2023-05-03T23:40:05","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=31530"},"modified":"2023-05-04T21:18:16","modified_gmt":"2023-05-04T14:18:16","slug":"yeu-to-tang-truong-tong-quan-linh-vuc-implant-nha-khoa","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/05\/04\/yeu-to-tang-truong-tong-quan-linh-vuc-implant-nha-khoa\/","title":{"rendered":"Y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng – T\u1ed5ng quan l\u0129nh v\u1ef1c Implant nha khoa."},"content":{"rendered":"

C\u00f4ng ngh\u1ec7 m\u00f4 l\u00e0 m\u1ed9t l\u0129nh v\u1ef1c \u0111i\u1ec1u tr\u1ecb thu\u1ed9c y h\u1ecdc t\u00e1i t\u1ea1o, s\u1eed d\u1ee5ng sinh h\u1ecdc v\u00e0 c\u00f4ng ngh\u1ec7 \u0111\u1ec3 ph\u1ee5c h\u1ed3i v\u00e0\/ ho\u1eb7c t\u0103ng c\u01b0\u1eddng ch\u1ee9c n\u0103ng m\u00f4. Khi \u00e1p d\u1ee5ng trong nha khoa c\u1ea5y gh\u00e9p v\u00e0 nha chu l\u00e2m s\u00e0ng, c\u00f4ng ngh\u1ec7 m\u00f4 gi\u00fap t\u1ea1o thu\u1eadn l\u1ee3i cho s\u1ef1 l\u00e0nh th\u01b0\u01a1ng v\u00e0 th\u00fac \u0111\u1ea9y t\u00e1i t\u1ea1o m\u00f4 \u0111\u00fang, v\u1edbi ti\u00ean l\u01b0\u1ee3ng t\u1ed1t h\u01a1n v\u00e0 \u00edt x\u00e2m l\u1ea5n h\u01a1n. \u0110\u1ed3ng th\u1eddi v\u1edbi \u0111\u00f3, c\u00e1c y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng l\u00e0 c\u00e1c ch\u1ea5t \u0111i\u1ec1u h\u00f2a quan tr\u1ecdng \u0111\u1ed1i v\u1edbi ch\u1ee9c n\u0103ng t\u1ebf b\u00e0o. B\u00e0i vi\u1ebft n\u00e0y t\u1eadp trung v\u1ec1 l\u0129nh v\u1ef1c c\u00f4ng ngh\u1ec7 m\u00f4 v\u00e0 c\u00e1c y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng \u0111\u1ed1i v\u1edbi s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a m\u00f4 trong Nha khoa. C\u00f9ng t\u00ecm hi\u1ec3u.<\/strong><\/p>\n

1. T\u1ed5ng quan v\u1ec1 c\u00f4ng ngh\u1ec7 m\u00f4 trong Nha khoa<\/h2>\n

C\u00f4ng ngh\u1ec7 m\u00f4 l\u00e0 m\u1ed9t l\u0129nh v\u1ef1c \u0111i\u1ec1u tr\u1ecb thu\u1ed9c y h\u1ecdc t\u00e1i t\u1ea1o, s\u1eed d\u1ee5ng sinh h\u1ecdc v\u00e0 c\u00f4ng ngh\u1ec7 \u0111\u1ec3 ph\u1ee5c h\u1ed3i v\u00e0\/ ho\u1eb7c t\u0103ng c\u01b0\u1eddng ch\u1ee9c n\u0103ng m\u00f4. Khi \u00e1p d\u1ee5ng trong nha khoa c\u1ea5y gh\u00e9p v\u00e0 nha chu l\u00e2m s\u00e0ng, c\u00f4ng ngh\u1ec7 m\u00f4 gi\u00fap t\u1ea1o thu\u1eadn l\u1ee3i cho s\u1ef1 l\u00e0nh th\u01b0\u01a1ng v\u00e0 th\u00fac \u0111\u1ea9y t\u00e1i t\u1ea1o m\u00f4 \u0111\u00fang, v\u1edbi ti\u00ean l\u01b0\u1ee3ng t\u1ed1t h\u01a1n v\u00e0 \u00edt x\u00e2m l\u1ea5n h\u01a1n.<\/p>\n

C\u00f4ng ngh\u1ec7 m\u00f4 g\u1ed3m c\u00f3 3 y\u1ebfu t\u1ed1: gi\u00e1 th\u1ec3, t\u1ebf b\u00e0o, v\u00e0 c\u00e1c y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng. Gi\u00e1 th\u1ec3 l\u00e0 nh\u1eefng khu\u00f4n c\u00f3 t\u00e1c d\u1ee5ng nh\u01b0 khung s\u01b0\u1eddn, cho ph\u00e9p t\u1ebf b\u00e0o t\u1eeb m\u00f4 xung quanh di c\u01b0 v\u00e0o v\u00f9ng thi\u1ebfu h\u1ed3ng, ch\u1eb3ng h\u1ea1n nh\u01b0 v\u1ecb tr\u00ed gh\u00e9p x\u01b0\u01a1ng. Gi\u00e1 th\u1ec3 c\u00f2n c\u00f3 t\u00e1c d\u1ee5ng l\u00e0 h\u1ec7 th\u1ed1ng v\u1eadn chuy\u1ec3n \u0111\u1ec3 chuy\u1ec3n c\u00e1c y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng ho\u1eb7c t\u1ebf b\u00e0o ngo\u1ea1i sinh \u0111\u1ebfn c\u00e1c v\u1ecb tr\u00ed thi\u1ebfu h\u1ed3ng. H\u01a1n n\u1eefa, \u0111\u00f4i khi, gi\u00e1 th\u1ec3 c\u00f2n t\u1ea1o ra s\u1ef1 to\u00e0n v\u1eb9n c\u1ea5u tr\u00fac c\u1ea7n thi\u1ebft cho vi\u1ec7c duy tr\u00ec kho\u1ea3ng t\u1ea1i v\u00f9ng gh\u00e9p. Nh\u1eefng t\u1ebf b\u00e0o c\u1ea7n thi\u1ebft cho c\u00e1c ho\u1ea1t \u0111\u1ed9ng sinh h\u1ecdc, bao g\u1ed3m c\u1ea3 t\u00e1i t\u1ea1o m\u00f4, c\u00f3 th\u1ec3 l\u00e0 t\u1ebf b\u00e0o t\u1ef1 th\u00e2n (t\u1eeb c\u01a1 th\u1ec3 ch\u1ee7) ho\u1eb7c \u0111\u1ed3ng lo\u1ea1i (t\u1eeb m\u1ed9t c\u00e1 th\u1ec3 kh\u00e1c c\u00f9ng lo\u00e0i). Nh\u1eefng v\u00ed d\u1ee5 v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng t\u1ebf b\u00e0o \u0111\u1ed3ng lo\u1ea1i trong nha chu l\u00e2m s\u00e0ng, bao g\u1ed3m c\u1ea3 li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o s\u1ed1ng, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong gh\u00e9p m\u00f4 m\u1ec1m v\u00e0 c\u00e1c ph\u1eabu thu\u1eadt t\u00e1i t\u1ea1o nha chu. C\u1ea3 hai lo\u1ea1i t\u1ebf b\u00e0o bi\u1ec7t h\u00f3a (v\u00ed d\u1ee5, nguy\u00ean b\u00e0o x\u01b0\u01a1ng, nguy\u00ean b\u00e0o s\u1ee3i) v\u00e0 ch\u01b0a bi\u1ec7t h\u00f3a (v\u00ed d\u1ee5, t\u1ebf b\u00e0o ti\u1ec1n th\u00e2n c\u1ee7a nguy\u00ean b\u00e0o x\u01b0\u01a1ng) \u0111\u1ec1u c\u1ea7n thi\u1ebft cho s\u1ef1 t\u00e1i t\u1ea1o m\u00f4. C\u00e1c y\u1ebfu t\u1ed1 n\u00e0y l\u00e0 c\u00e1c ch\u1ea5t \u0111i\u1ec1u h\u00f2a quan tr\u1ecdng \u0111\u1ed1i v\u1edbi ch\u1ee9c n\u0103ng t\u1ebf b\u00e0o. Khi c\u00f3 m\u1eb7t c\u1ea3 3 y\u1ebfu t\u1ed1, c\u00f9ng v\u1edbi m\u00f4i tr\u01b0\u1eddng v\u00e0 th\u1eddi gian l\u00e0nh th\u01b0\u01a1ng th\u00edch h\u1ee3p, th\u00ec s\u1ef1 t\u00e1i t\u1ea1o m\u00f4 c\u00f3 th\u1ec3 x\u1ea3y ra.<\/p>\n

2. \u0110\u1eb7c \u0111i\u1ec3m c\u00e1c y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng \u0111\u1ed1i v\u1edbi s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a m\u00f4<\/h2>\n

C\u00e1c y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng l\u00e0 nh\u1eefng ph\u00e2n t\u1eed t\u1ef1 nhi\u00ean \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi c\u01a1 th\u1ec3 nh\u1eb1m k\u00edch th\u00edch v\u00e0 \u0111i\u1ec1u khi\u1ec3n c\u00e1c ho\u1ea1t \u0111\u1ed9ng t\u1ebf b\u00e0o. C\u1ee5 th\u1ec3, c\u00e1c y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng c\u00f3 th\u1ec3 ho\u1ea1t \u0111\u1ed9ng nh\u01b0 nh\u1eefng t\u00e1c nh\u00e2n h\u00f3a h\u01b0\u1edbng b\u1eb1ng c\u00e1ch huy \u0111\u1ed9ng t\u1ebf b\u00e0o, th\u1ef1c hi\u1ec7n nguy\u00ean ph\u00e2n b\u1eb1ng c\u00e1ch g\u00e2y t\u0103ng sinh t\u1ebf b\u00e0o, v\u00e0 t\u1ea1o h\u00ecnh th\u00e1i b\u1eb1ng c\u00e1ch k\u00edch th\u00edch s\u1ef1 bi\u1ec7t h\u00f3a t\u1ebf b\u00e0o. Nh\u01b0 v\u1eady, c\u00e1c y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng c\u00f3 t\u00ednh c\u1ea3m \u1ee9ng x\u01b0\u01a1ng (c\u1ea3m \u1ee9ng x\u01b0\u01a1ng l\u00e0 m\u1ed9t qu\u00e1 tr\u00ecnh m\u00e0 trong \u0111\u00f3 nh\u1eefng ph\u00e2n t\u1eed, ch\u1eb3ng h\u1ea1n nh\u01b0 c\u00e1c y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng trong v\u1eadt li\u1ec7u x\u01b0\u01a1ng gh\u00e9p, chuy\u1ec3n c\u00e1c t\u1ebf b\u00e0o l\u00e2n c\u1eadn trong c\u01a1 th\u1ec3 ch\u1ee7 th\u00e0nh nguy\u00ean b\u00e0o t\u1ea1o x\u01b0\u01a1ng, t\u1eeb \u0111\u00f3 h\u00ecnh th\u00e0nh x\u01b0\u01a1ng m\u1edbi).<\/p>\n

Y h\u1ecdc t\u00e1i t\u1ea1o \u0111\u00e3 s\u1eed d\u1ee5ng c\u00f4ng ngh\u1ec7 c\u1ee7a li\u1ec7u ph\u00e1p protein t\u00e1i t\u1ed5 h\u1ee3p trong ph\u00f2ng th\u00ed nghi\u1ec7m \u0111\u1ec3 t\u1ed5ng h\u1ee3p c\u00e1c y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng c\u00f3 th\u1ec3 th\u1ef1c hi\u1ec7n nh\u1eefng ch\u1ee9c n\u0103ng sinh h\u1ecdc c\u1ee7a y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng t\u1ef1 nhi\u00ean. Cho \u0111\u1ebfn nay, c\u00f3 hai y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng t\u00e1i t\u1ed5 h\u1ee3p c\u1ee7a ng\u01b0\u1eddi \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong nha khoa l\u00e0 thPDGF-BB v\u00e0 rhBMP-2. Ch\u1ec9 c\u00f3 rhBMP-2 l\u00e0 \u0111\u01b0\u1ee3c c\u00f4ng nh\u1eadn \u0111\u1ec3 ph\u00e1t tri\u1ec3n v\u1ecb tr\u00ed c\u1ea5y gh\u00e9p t\u1ea1i th\u1eddi \u0111i\u1ec3m n\u00e0y. Hi\u1ec7n nay, nh\u1eefng y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng kh\u00e1c \u0111ang \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n \u0111\u1ec3 s\u1eed d\u1ee5ng trong nha khoa, ch\u1eb3ng h\u1ea1n nh\u01b0 protein t\u1ea1o h\u00ecnh th\u00e1i x\u01b0\u01a1ng-7, y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng nguy\u00ean b\u00e0o s\u1ee3i c\u01a1 b\u1ea3n, y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng n\u1ed9i m\u00f4 m\u1ea1ch m\u00e1u (VEGF), y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng\/bi\u1ec7t h\u00f3a-5, v\u00e0 y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng gi\u1ea3 insulin.<\/p>\n

rhPDGF-BB l\u00e0 m\u1ed9t ph\u00e2n t\u1eed protein t\u1ed5ng h\u1ee3p m\u00f4 ph\u1ecfng y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng c\u00f3 ngu\u1ed3n g\u1ed1c ti\u1ec3u c\u1ea7u t\u1ef1 nhi\u00ean (PDGF)-BB. PDGF ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t, l\u01b0u tr\u1eef, v\u00e0 ph\u00f3ng th\u00edch b\u1edfi ti\u1ec3u c\u1ea7u t\u1ea1i v\u1ecb tr\u00ed t\u1ed5n th\u01b0\u01a1ng, v\u00e0 \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 tham gia v\u00e0o qu\u00e1 tr\u00ecnh l\u00e0nh th\u01b0\u01a1ng m\u00f4 m\u1ec1m c\u0169ng nh\u01b0 t\u00e1i t\u1ea1o c\u1ea5u tr\u00fac x\u01b0\u01a1ng. PDGF huy \u0111\u1ed9ng nguy\u00ean b\u00e0o s\u1ee3i n\u01b0\u1edbu (h\u00f3a h\u01b0\u1edbng) v\u00e0 k\u00edch th\u00edch ch\u00fang t\u0103ng sinh (nguy\u00ean ph\u00e2n), l\u00e0 nh\u1eefng s\u1ef1 ki\u1ec7n c\u1ea7n thi\u1ebft cho s\u1ef1 l\u00e0nh th\u01b0\u01a1ng c\u1ee7a m\u00f4 li\u00ean k\u1ebft. PDGF c\u00f2n k\u00edch t\u1ea1o m\u1ea1ch l\u00e0 qu\u00e1 tr\u00ecnh h\u00ecnh th\u00e0nh m\u1ea1ch m\u00e1u m\u1edbi \u0111\u1ec3 cung c\u1ea5p ch\u1ea5t dinh d\u01b0\u1ee1ng cho v\u00f9ng gh\u00e9p. V\u00e0o n\u0103m 2005, FDA \u0111\u00e3 c\u00f4ng nh\u1eadn rhPDGF -BB, v\u00e0 n\u00f3 \u0111\u01b0\u1ee3c \u0111\u01b0a ra th\u1ecb tr\u01b0\u1eddng d\u01b0\u1edbi d\u1ea1ng khu\u00f4n t\u0103ng c\u01b0\u1eddng y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng Gem 21S (Osteohealth), \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong thi\u1ebfu h\u1ed3ng nha chu trong x\u01b0\u01a1ng, khi\u1ebfm khuy\u1ebft nha chu v\u00f9ng ch\u1ebd, v\u00e0 t\u1ee5t n\u01b0\u1edbu do thi\u1ebfu h\u1ed3ng nha chu. rhPDGF-BB c\u0169ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i ngo\u00e0i h\u01b0\u1edbng d\u1eabn ch\u1ec9 \u0111\u1ecbnh b\u1edfi nhi\u1ec1u b\u00e1c s\u0129 l\u00e2m s\u00e0ng trong c\u00e1c ph\u1eabu thu\u1eadt gh\u00e9p x\u01b0\u01a1ng trong mi\u1ec7ng kh\u00e1c, ch\u1eb3ng h\u1ea1n nh\u01b0 gh\u00e9p \u1ed5 r\u0103ng v\u00e0 gh\u00e9p s\u1ed1ng h\u00e0m.<\/p>\n

rhBMP-2 l\u00e0 m\u1ed9t ph\u00e2n t\u1eed protein t\u1ed5ng h\u1ee3p th\u1ef1c hi\u1ec7n nh\u1eefng ch\u1ee9c n\u0103ng sinh h\u1ecdc gi\u1ed1ng nh\u01b0 protein t\u1ea1o h\u00ecnh th\u00e1i x\u01b0\u01a1ng t\u1ef1 nhi\u00ean (BMP)-2. BMP-2 l\u00e0 m\u1ed9t ch\u1ea5t t\u1ea1o h\u00ecnh th\u00e1i c\u00f3 kh\u1ea3 n\u0103ng k\u00edch t\u1ea1o x\u01b0\u01a1ng m\u1edbi b\u1eb1ng c\u00e1ch k\u00edch th\u00edch t\u1ebf b\u00e0o trung m\u00f4 bi\u1ec7t h\u00f3a th\u00e0nh nguy\u00ean b\u00e0o x\u01b0\u01a1ng. BMPs hi\u1ec7n di\u1ec7n trong m\u1ed9t l\u01b0\u1ee3ng x\u01b0\u01a1ng v\u1ecf r\u1ea5t nh\u1ecf \u1edf ng\u01b0\u1eddi, \u01b0\u1edbc t\u00ednh kho\u1ea3ng 1-2 ug\/kg. FDA Hoa K\u1ef3 \u0111\u00e3 c\u00f4ng nh\u1eadn rhBMP-2, v\u00e0 n\u00f3 \u0111\u01b0\u1ee3c \u0111\u01b0a ra th\u1ecb tr\u01b0\u1eddng d\u01b0\u1edbi d\u1ea1ng x\u01b0\u01a1ng gh\u00e9p INFUSE\u00ae (BioHorizon), \u0111\u01b0\u1ee3c \u1ee9ng d\u1ee5ng trong nha khoa \u0111\u1ec3 gh\u00e9p s\u1ed1ng h\u00e0m t\u1ea1i \u1ed5 nh\u1ed5 r\u0103ng v\u00e0 ph\u1eabu thu\u1eadt n\u00e2ng xoang gh\u00e9p x\u01b0\u01a1ng. Gi\u1ed1ng nh\u01b0 rhPDGF-BB, vi\u1ec7c s\u1eed d\u1ee5ng rhBMP-2 ngo\u00e0i h\u01b0\u1edbng d\u1eabn ch\u1ec9 \u0111\u1ecbnh c\u0169ng \u0111ang ph\u1ed5 bi\u1ebfn v\u1edbi c\u00e1c b\u00e1c s\u0129 l\u00e2m s\u00e0ng trong ph\u1eabu thu\u1eadt gh\u00e9p s\u1ed1ng h\u00e0m.<\/p>\n

\"yeu-to-tang-truong\"
rhBMP-2<\/figcaption><\/figure>\n

Ngu\u1ed3n t\u00e0i li\u1ec7u: Clinical Cases in Implant Dentistry, First Edition – Published 2017 by John Wiley & Sons, Inc.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

C\u00f4ng ngh\u1ec7 m\u00f4 l\u00e0 m\u1ed9t l\u0129nh v\u1ef1c \u0111i\u1ec1u tr\u1ecb thu\u1ed9c y h\u1ecdc t\u00e1i t\u1ea1o, s\u1eed d\u1ee5ng sinh h\u1ecdc v\u00e0 c\u00f4ng ngh\u1ec7 \u0111\u1ec3 ph\u1ee5c h\u1ed3i v\u00e0\/ ho\u1eb7c t\u0103ng c\u01b0\u1eddng ch\u1ee9c n\u0103ng m\u00f4. Khi \u00e1p d\u1ee5ng trong nha khoa c\u1ea5y gh\u00e9p v\u00e0 nha chu l\u00e2m s\u00e0ng, c\u00f4ng ngh\u1ec7 m\u00f4 gi\u00fap t\u1ea1o thu\u1eadn l\u1ee3i cho s\u1ef1 l\u00e0nh th\u01b0\u01a1ng […]<\/p>\n","protected":false},"author":21,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[28,33],"tags":[],"yoast_head":"\nY\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng - T\u1ed5ng quan l\u0129nh v\u1ef1c Implant nha khoa.<\/title>\n<meta name=\"description\" content=\"B\u00e0i vi\u1ebft n\u00e0y t\u1eadp trung v\u1ec1 l\u0129nh v\u1ef1c c\u00f4ng ngh\u1ec7 m\u00f4 v\u00e0 c\u00e1c y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng \u0111\u1ed1i v\u1edbi s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a m\u00f4 trong Nha khoa. 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