{"id":30929,"date":"2023-05-03T14:55:27","date_gmt":"2023-05-03T07:55:27","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=30929"},"modified":"2023-05-03T14:55:27","modified_gmt":"2023-05-03T07:55:27","slug":"tiep-can-hoi-chung-giam-hoat-giap","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/05\/03\/tiep-can-hoi-chung-giam-hoat-giap\/","title":{"rendered":"Ti\u1ebfp c\u1eadn h\u1ed9i ch\u1ee9ng gi\u1ea3m ho\u1ea1t gi\u00e1p"},"content":{"rendered":"<p><strong>H\u1ed9i ch\u1ee9ng gi\u1ea3m ho\u1ea1t gi\u00e1p l\u00e0 nh\u1eefng bi\u1ec3u hi\u1ec7n l\u00e2m s\u00e0ng v\u00e0 c\u1eadn l\u00e2m s\u00e0ng c\u1ee7a c\u00e1c c\u01a1 quan \u0111\u00edch c\u1ee7a c\u01a1 th\u1ec3 x\u1ea3y ra do gi\u1ea3m s\u1ea3n xu\u1ea5t v\u00e0\/ho\u1eb7c gi\u1ea3m t\u00e1c d\u1ee5ng hormon gi\u00e1p. N\u1ebfu kh\u00f4ng nh\u1eadn bi\u1ebft s\u1edbm v\u00e0 \u0111i\u1ec1u tr\u1ecb, suy gi\u00e1p c\u00f3 th\u1ec3 d\u1eabn t\u1edbi c\u00e1c bi\u1ebfn ch\u1ee9ng nghi\u00eam tr\u1ecdng.<\/strong><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone wp-image-30930 size-medium\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/20190831_110307_198495_hormon-thyroxin.max-800x800-1-300x212.jpg\" alt=\"hoi-chung-giam-ho\u1ea1t-giap\" width=\"300\" height=\"212\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/20190831_110307_198495_hormon-thyroxin.max-800x800-1-300x212.jpg 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/20190831_110307_198495_hormon-thyroxin.max-800x800-1-768x542.jpg 768w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/20190831_110307_198495_hormon-thyroxin.max-800x800-1.jpg 800w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/p>\n<h2><strong>1. Nguy\u00ean nh\u00e2n <\/strong>h\u1ed9i ch\u1ee9ng gi\u1ea3m ho\u1ea1t gi\u00e1p<\/h2>\n<p><strong>1.1. Ti\u00ean ph\u00e1t<\/strong><\/p>\n<p>95% tr\u01b0\u1eddng h\u1ee3p.<\/p>\n<p>&#8211; Vi\u00eam tuy\u1ebfn gi\u00e1p Hashimoto.<\/p>\n<p>&#8211; \u0110i\u1ec1u tr\u1ecb b\u1eb1ng ph\u1eabu thu\u1eadt, I<sup>131<\/sup> hay x\u1ea1 tr\u1ecb b\u1ec7nh tuy\u1ebfn gi\u00e1p<\/p>\n<p>&#8211; \u1ee8c ch\u1ebf t\u1ed5ng h\u1ee3p hormon gi\u00e1p : do th\u1eeba hay thi\u1ebfu iode; x\u1eef d\u1ee5ng thu\u1ed1c lithium, amiodarone.<\/p>\n<p>&#8211; B\u1ea5t th\u01b0\u1eddng sinh t\u1ed5ng h\u1ee3p hormon gi\u00e1p.<\/p>\n<p>&#8211; Hi\u1ebfm h\u01a1n: nhi\u1ec5m s\u1eafc t\u1ed1 s\u1eaft, sarcoidosis, amyloidosis.<\/p>\n<p><strong>1.2. Th\u1ee9 ph\u00e1t <\/strong><\/p>\n<p>&#8211; Suy tuy\u1ebfn y\u00ean do u tuy\u1ebfn y\u00ean, do ph\u1eabu thu\u1eadt.<\/p>\n<p>&#8211; X\u1ea1 tr\u1ecb v\u00f9ng \u0111\u1ea7u-c\u1ed5 trong u tuy\u1ebfn y\u00ean.<\/p>\n<p>&#8211; Nhi\u1ec5m s\u1eafc t\u1ed1 s\u1eaft, Sarcoidosis.<\/p>\n<p>&#8211; \u0110\u1ed9t bi\u1ebfn th\u1ee5 th\u1ec3 TRH.<\/p>\n<p>&#8211; R\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng v\u00f9ng d\u01b0\u1edbi \u0111\u1ed3i l\u00e0m gi\u1ea3m s\u1ea3n xu\u1ea5t v\u00e0\/ho\u1eb7c ph\u00f3ng th\u00edch TRH. Th\u01b0\u1eddng ph\u1ed1i h\u1ee3p v\u1edbi b\u1ec7nh l\u00fd tuy\u1ebfn y\u00ean.<\/p>\n<p><strong>1.3. Nguy\u00ean nh\u00e2n \u0111\u1eb7c bi\u1ec7t<\/strong><\/p>\n<p>&#8211; \u0110\u1ec1 kh\u00e1ng ngo\u1ea1i bi\u00ean v\u1edbi t\u00e1c d\u1ee5ng hormon gi\u00e1p.<\/p>\n<p>&#8211; B\u1ea5t th\u01b0\u1eddng th\u1ee5 th\u1ec3 T<sub>4<\/sub> \u1edf t\u1ebf b\u00e0o.<\/p>\n<h1>2. Tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng h\u1ed9i ch\u1ee9ng gi\u1ea3m ho\u1ea1t gi\u00e1p<\/h1>\n<p>Tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng \u0111a d\u1ea1ng do nhi\u1ec1u c\u01a1 quan \u0111\u00edch c\u1ee7a c\u01a1 th\u1ec3 b\u1ecb \u1ea3nh h\u01b0\u1edfng, li\u00ean quan b\u1ec7nh nguy\u00ean, tu\u1ed5i t\u00e1c v\u00e0 nh\u1ea5t l\u00e0 tu\u1ef3 thu\u1ed9c v\u00e0o th\u1eddi gian v\u00e0 m\u1ee9c \u0111\u1ed9 thi\u1ebfu h\u1ee5t hormone gi\u00e1p . C\u00e1c tri\u1ec7u ch\u1ee9ng th\u01b0\u1eddng g\u1eb7p nh\u01b0 sau .<\/p>\n<p><strong>2.1. T\u0103ng tr\u01b0\u1edfng v\u00e0 ph\u00e1t tri\u1ec3n c\u01a1 th\u1ec3<\/strong><\/p>\n<p>Bi\u1ec3u hi\u1ec7n r\u00f5 trong giai \u0111o\u1ea1n tr\u1ebb nh\u1ecf v\u00e0 th\u1eddi k\u1ef3 ni\u00ean thi\u1ebfu.<\/p>\n<p>S\u1ef1 ph\u00e1t tri\u1ec3n v\u00e0 bi\u1ec7t ho\u00e1 c\u1ee7a n\u00e3o x\u1ea3y ra ph\u1ea7n l\u1edbn (2\/3) trong v\u00f2ng 2 n\u0103m \u0111\u1ea7u ti\u00ean; v\u00ec v\u1eady vi\u1ec7c thay th\u1ebf s\u1edbm b\u1eb1ng hormon gi\u00e1p ngay sau sinh s\u1ebd l\u00e0m h\u1ea1n ch\u1ebf t\u1ed1i \u0111a th\u01b0\u01a1ng t\u1ed5n n\u00e3o v\u0129nh vi\u1ec5n. Thi\u1ebfu h\u1ee5t hormon gi\u00e1p sau 3 tu\u1ed5i kh\u00f4ng g\u00e2y ch\u1eadm ph\u00e1t tri\u1ec3n tinh th\u1ea7n, nh\u01b0ng l\u1ea1i g\u00e2y ch\u1eadm ph\u00e1t tri\u1ec3n c\u01a1 th\u1ec3, ch\u1eadm ph\u00e1t tri\u1ec3n x\u01b0\u01a1ng d\u00e0i c\u0169ng nh\u01b0 ch\u1eadm m\u1ecdc r\u0103ng v\u0129nh vi\u1ec5n.<\/p>\n<p><strong>2.2. Da-ni\u00eam m\u1ea1c<\/strong><\/p>\n<p>&#8211; M\u1eb7t tr\u00f2n nh\u01b0 m\u1eb7t tr\u0103ng, \u00edt bi\u1ec3u l\u1ed9 t\u00ecnh c\u1ea3m, tr\u00e1n nhi\u1ec1u n\u1ebfp nh\u0103n.<\/p>\n<p>&#8211; M\u00ed m\u1eaft ph\u00f9, nh\u1ea5t l\u00e0 mi d\u01b0\u1edbi.<\/p>\n<p>&#8211; G\u00f2 m\u00e1 t\u00edm, nhi\u1ec1u mao m\u1ea1ch b\u1ecb d\u00e3n; m\u00f4i d\u1ea7y v\u00e0 t\u00edm.<\/p>\n<p>&#8211; Da \u1edf v\u00f9ng m\u1eb7t v\u00e0 b\u00e0n tay c\u00f3 m\u00e0u v\u00e0ng b\u1ee7ng ( th\u00e2m nhi\u1ec3m caroten ) .<\/p>\n<p>&#8211; B\u00e0n tay, b\u00e0n ch\u00e2n d\u1ea7y, c\u00e1c ng\u00f3n to v\u00e0 d\u1ea7y, kh\u00f3 g\u1ea5p b\u00e0n tay, b\u00e0n ch\u00e2n.<\/p>\n<p>&#8211; Ni\u00eam m\u1ea1c l\u01b0\u1ee1i b\u1ecb x\u00e2m nhi\u1ec5m l\u00e0m cho l\u01b0\u1ee1i to ra; d\u00e2y thanh \u00e2m b\u1ecb th\u00e2m nhi\u1ec5m l\u00e0m gi\u1ecdng n\u00f3i kh\u00e0n; ni\u00eam m\u1ea1c v\u00f2i Eustache b\u1ecb x\u00e2m nhi\u1ec5m g\u00e2y \u00f9 tai, nghe k\u00e9m.<\/p>\n<p>&#8211; Da kh\u00f4 bong v\u1ea3y.<\/p>\n<p>&#8211; T\u00f3c kh\u00f4, d\u1ec5 r\u1ee5ng; ph\u00eda ngo\u00e0i ch\u00e2n m\u00e0y th\u01b0a ho\u1eb7c r\u1ee5ng h\u1ebft (d\u1ea5u hi\u1ec7u \u201c\u0111u\u00f4i ch\u00e2n m\u00e0y\u201d); l\u00f4ng n\u00e1ch, l\u00f4ng mu r\u1ee5ng.<\/p>\n<p><strong>2.3. Chuy\u1ec3n ho\u00e1<\/strong><\/p>\n<p>&#8211; S\u1ee3 l\u1ea1nh.<\/p>\n<p>&#8211; Ch\u1eadm h\u1ea5p thu glucose \u1edf ru\u1ed9t, gi\u1ea3m s\u1eed d\u1ee5ng glucose v\u00e0 \u0111\u1ec1 kh\u00e1ng insulin.<\/p>\n<p>&#8211; T\u0103ng c\u00e2n d\u00f9 \u0103n k\u00e9m. M\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n t\u0103ng c\u00e2n v\u1eeba ph\u1ea3i do \u1ee9 d\u1ecbch.<\/p>\n<p><strong>2.4. Th\u1ea7n kinh<\/strong><\/p>\n<p>\u0110au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t, r\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n, r\u1ed1i lo\u1ea1n nh\u1eadn th\u1ee9c, \u0111i\u1ebfc, \u00f9 tai, d\u1ecb c\u1ea3m.<\/p>\n<p><strong>2.5. Tim m\u1ea1ch<\/strong><\/p>\n<p>&#8211; Nh\u1ecbp ch\u1eadm, th\u1ec3 t\u00edch t\u1ed1ng m\u00e1u gi\u1ea3m, l\u01b0u l\u01b0\u1ee3ng tim gi\u1ea3m, tr\u00e0n d\u1ecbch m\u00e0ng tim.<\/p>\n<p><strong>2.6. C\u01a1 x\u01b0\u01a1ng kh\u1edbp<\/strong><\/p>\n<p>&#8211; M\u1ecfi, y\u1ebfu c\u01a1, co r\u00fat c\u01a1.<\/p>\n<p>&#8211; C\u00f3 th\u1ec3 \u0111au kh\u1edbp, tr\u00e0n d\u1ecbch kh\u1edbp ho\u1eb7c gi\u1ea3 b\u1ec7nh g\u00fat.<\/p>\n<p>&#8211; \u1ede tr\u1ebb em: ch\u1eadm ph\u00e1t tri\u1ec3n x\u01b0\u01a1ng d\u00e0i.<\/p>\n<p><strong>2.7. D\u1ea1 d\u00e0y-ru\u1ed9t<\/strong><\/p>\n<p>&#8211; T\u00e1o b\u00f3n, ch\u01b0\u1edbng b\u1ee5ng.<\/p>\n<p>&#8211; Gi\u1ea3m ti\u1ebft d\u1ecbch d\u1ea1 d\u00e0y do vi\u00eam teo th\u00e2n d\u1ea1 d\u00e0y teo trong vi\u00eam tuy\u1ebfn gi\u00e1p.<\/p>\n<p>&#8211; Kh\u00e1ng th\u1ec3 ch\u1ed1ng l\u1ea1i t\u1ebf b\u00e0o th\u00e0nh d\u1ea1 d\u00e0y v\u00e0 thi\u1ebfu m\u00e1u \u00e1c t\u00ednh th\u01b0\u1eddng g\u1eb7p \u1edf b\u1ec7nh l\u00fd gi\u00e1p t\u1ef1 mi\u1ec5n.<\/p>\n<p><strong>2.8. Sinh d\u1ee5c<\/strong><\/p>\n<ul>\n<li>\u1ede n\u1eef: r\u1ed1i lo\u1ea1n kinh nguy\u1ec7t, kh\u00f4ng r\u1ee5ng tr\u1ee9ng, v\u00f4 sinh.<\/li>\n<li>Gi\u1ea3m ho\u1ea1t gi\u00e1p khi c\u00f3 thai c\u00f3 th\u1ec3 g\u00e2y thai l\u01b0u, sinh non, t\u0103ng huy\u1ebft \u00e1p v\u00e0 xu\u1ea5t huy\u1ebft sau sinh.<\/li>\n<\/ul>\n<p>&#8211; \u1ede nam: b\u1ea5t th\u01b0\u1eddng ch\u1ee9c n\u0103ng sinh d\u1ee5c.<\/p>\n<p><strong>2.9. N\u1ed9i ti\u1ebft<\/strong><\/p>\n<p>C\u00f3 ho\u1eb7c kh\u00f4ng c\u00f3 b\u01b0\u1edbu gi\u00e1p: b\u01b0\u1edbu gi\u00e1p ch\u1ec9 c\u00f3 trong 1 s\u1ed1 nguy\u00ean nh\u00e2n \u0111\u1eb7c bi\u1ec7t ( vi\u00eam tuy\u1ebfn gi\u00e1p Hashimoto, do r\u1ed1i lo\u1ea1n chuy\u1ec3n ho\u00e1 iode &#8230;).<\/p>\n<p>&nbsp;<\/p>\n<p>T\u00f3m t\u1eaft t\u1ea7n su\u1ea5t th\u01b0\u1eddng g\u1eb7p c\u00e1c tri\u1ec7u ch\u1ee9ng \u1edf b\u1ec7nh nh\u00e2n suy gi\u00e1p:<\/p>\n<p>&nbsp;<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"357\">Tri\u1ec7u ch\u1ee9ng gi\u1ea3m chuy\u1ec3n ho\u00e1:<\/td>\n<td width=\"79\">%<\/td>\n<td width=\"317\"><\/td>\n<td width=\"82\">%<\/td>\n<\/tr>\n<tr>\n<td width=\"357\">+ M\u1ec7t m\u1ecfi<\/td>\n<td width=\"79\">99<\/td>\n<td width=\"317\">+ R\u1ee5ng t\u00f3c<\/td>\n<td width=\"82\">57<\/td>\n<\/tr>\n<tr>\n<td width=\"357\">+ S\u1ee3 r\u00e9t<\/td>\n<td width=\"79\">89<\/td>\n<td width=\"317\">+ Ph\u00f9 ngo\u1ea1i vi<\/td>\n<td width=\"82\">55<\/td>\n<\/tr>\n<tr>\n<td width=\"357\">+ T\u0103ng c\u00e2n<\/td>\n<td width=\"79\">59<\/td>\n<td width=\"317\">+ Gi\u1ecdng kh\u00e0n<\/td>\n<td width=\"82\">52<\/td>\n<\/tr>\n<tr>\n<td width=\"357\">Tri\u1ec7u ch\u1ee9ng tim m\u1ea1ch:<\/td>\n<td width=\"79\"><\/td>\n<td width=\"317\">+ \u0110i\u1ebfc<\/td>\n<td width=\"82\">32<\/td>\n<\/tr>\n<tr>\n<td width=\"357\">+ Nh\u1ecbp tim ch\u1eadm<\/td>\n<td width=\"79\">95<\/td>\n<td width=\"317\">Tri\u1ec7u ch\u1ee9ng ti\u00eau ho\u00e1:<\/td>\n<td width=\"82\"><\/td>\n<\/tr>\n<tr>\n<td width=\"357\">+ H\u1ed3i h\u1ed9p<\/td>\n<td width=\"79\">31<\/td>\n<td width=\"317\">+ T\u00e1o b\u00f3n dai d\u1eb3ng<\/td>\n<td width=\"82\">23<\/td>\n<\/tr>\n<tr>\n<td width=\"357\">+ \u0110au v\u00f9ng tr\u01b0\u1edbc tim<\/td>\n<td width=\"79\">25<\/td>\n<td width=\"317\">Tri\u1ec7u ch\u1ee9ng c\u01a1 b\u1eafp:<\/td>\n<td width=\"82\"><\/td>\n<\/tr>\n<tr>\n<td width=\"357\">Tri\u1ec7u ch\u1ee9ng da, ni\u00eam m\u1ea1c:<\/td>\n<td width=\"79\"><\/td>\n<td width=\"317\">+ Chu\u1ed9t r\u00fat<\/td>\n<td width=\"82\">70<\/td>\n<\/tr>\n<tr>\n<td width=\"357\">+ Da kh\u00f4<\/td>\n<td width=\"79\">97<\/td>\n<td width=\"317\">Tri\u1ec7u ch\u1ee9ng th\u1ea7n kinh:<\/td>\n<td width=\"82\"><\/td>\n<\/tr>\n<tr>\n<td width=\"357\">+ Gi\u1ea3m ti\u1ebft m\u1ed3 h\u00f4i<\/td>\n<td width=\"79\">89<\/td>\n<td width=\"317\">+ L\u1eeb \u0111\u1eeb<\/td>\n<td width=\"82\">91<\/td>\n<\/tr>\n<tr>\n<td width=\"357\">+ L\u01b0\u1ee1i l\u1edbn v\u00e0 d\u00e0y<\/td>\n<td width=\"79\">82<\/td>\n<td width=\"317\">+ N\u00f3i ch\u1eadm<\/td>\n<td width=\"82\">91<\/td>\n<\/tr>\n<tr>\n<td width=\"357\">+ R\u1ee5ng l\u00f4ng<\/td>\n<td width=\"79\">76<\/td>\n<td width=\"317\">+ Hay qu\u00ean<\/td>\n<td width=\"82\">66<\/td>\n<\/tr>\n<tr>\n<td width=\"357\">+ Xanh t\u00e1i<\/td>\n<td width=\"79\">67<\/td>\n<td width=\"317\">+ R\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n<\/td>\n<td width=\"82\">35<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<h2>3. C\u1eadn l\u00e2m s\u00e0ng<\/h2>\n<p><strong>3.1. X\u00e9t nghi\u1ec7m \u0111\u00e1nh g\u00eda ch\u1ee9c n\u0103ng tuy\u1ebfn gi\u00e1p<\/strong><\/p>\n<p><strong><em>3.1.1. Hormon gi\u00e1p <\/em><\/strong><\/p>\n<p>\u0110\u1ecbnh l\u01b0\u1ee3ng hormone gi\u00e1p l\u00e0 tri\u1ec7u ch\u1ee9ng quan tr\u1ecdng trong ch\u1ea9n \u0111o\u00e1n, trong \u0111\u00f3 n\u1ed3ng \u0111\u1ed9 d\u1ea1ng t\u1ef1 do FT<sub>4<\/sub> ( n\u1ed3ng \u0111\u1ed9 b\u00ecnh th\u01b0\u1eddng t\u1eeb 0,8 &#8211; 2,7 ng \/ dl ho\u1eb7c 10 &#8211; 35 pmol \/l)\u00a0 quan tr\u1ecdng h\u01a1n n\u1ed3ng \u0111\u1ed9 T<sub>4<\/sub> to\u00e0n ph\u1ea7n v\u00ec lo\u1ea1i tr\u1eeb tr\u01b0\u1eddng h\u1ee3p t\u0103ng n\u1ed3ng \u0111\u1ed9 c\u00e1c protein k\u1ebft h\u1ee3p. FT<sub>4<\/sub> quan tr\u1ecdng h\u01a1n FT<sub>3<\/sub> (gi\u1ea3m FT<sub>3<\/sub> g\u1eb7p \u1edf ng\u01b0\u1eddi gi\u00e0, s\u1eed d\u1ee5ng amiodarone, nhi\u1ec5m tr\u00f9ng n\u1eb7ng).<\/p>\n<p>\u0110\u1eb7c \u0111i\u1ec3m TSH,FT4 v\u00e0 T3\u00a0 qua c\u00e1c m\u1ee9c \u0111\u1ed9 gi\u1ea3m ho\u1ea1t gi\u00e1p:<\/p>\n<p>&nbsp;<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"374\">M\u1ee9c \u0111\u1ed9 gi\u1ea3m ho\u1ea1t gi\u00e1p<\/td>\n<td width=\"108\">TSH<\/td>\n<td width=\"216\">FT<sub>4<\/sub><\/td>\n<td width=\"216\">T<sub>3<\/sub><\/td>\n<\/tr>\n<tr>\n<td width=\"374\">Gi\u1ea3m ho\u1ea1t gi\u00e1p c\u1eadn l\u00e2m s\u00e0ng<\/td>\n<td width=\"108\">t\u0103ng<\/td>\n<td width=\"216\">b\u00ecnh th\u01b0\u1eddng<\/td>\n<td width=\"216\">b\u00ecnh th\u01b0\u1eddng<\/td>\n<\/tr>\n<tr>\n<td width=\"374\">Gi\u1ea3m ho\u1ea1t gi\u00e1p nh\u1eb9<\/td>\n<td width=\"108\">t\u0103ng<\/td>\n<td width=\"216\">b\u00ecnh th\u01b0\u1eddng\/gi\u1ea3m<\/td>\n<td width=\"216\">b\u00ecnh th\u01b0\u1eddng\/gi\u1ea3m<\/td>\n<\/tr>\n<tr>\n<td width=\"374\">Gi\u1ea3m ho\u1ea1t gi\u00e1p r\u00f5<\/td>\n<td width=\"108\">t\u0103ng<\/td>\n<td width=\"216\">gi\u1ea3m<\/td>\n<td width=\"216\">gi\u1ea3m<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Gi\u1ea3m ho\u1ea1t gi\u00e1p ti\u00ean ph\u00e1t l\u00e0 nguy\u00ean nh\u00e2n th\u01b0\u1eddng g\u1eb7p nh\u1ea5t c\u1ee7a t\u0103ng TSH. T<sub>4<\/sub> gi\u1ea3m s\u1edbm, trong khi T<sub>3<\/sub> v\u1eabn c\u00f2n b\u00ecnh th\u01b0\u1eddng cho \u0111\u1ebfn khi ch\u1ee9c n\u0103ng tuy\u1ebfn gi\u00e1p b\u1ecb \u1ea3nh h\u01b0\u1edfng n\u1eb7ng.<\/p>\n<p><strong><em>3.1.2. \u0110\u1ed9 t\u1eadp trung Iode ph\u00f3ng x\u1ea1 <\/em><\/strong><\/p>\n<p>\u0110\u00e1nh gi\u00e1 ch\u1ee9c n\u0103ng thu nh\u1eadn iode c\u1ee7a tuy\u1ebfn gi\u00e1p. C\u00f3 th\u1ec3 th\u1ea5p h\u01a1n b\u00ecnh th\u01b0\u1eddng trong ph\u1ea7n l\u1edbn tr\u01b0\u1eddng h\u1ee3p nh\u01b0ng \u0111\u1ed9 t\u1eadp trung c\u00f3 th\u1ec3 t\u0103ng trong ch\u1ee9ng thi\u1ebfu h\u1ee5t iode.<\/p>\n<p><strong>3.2. X\u00e9t nghi\u1ec7m ch\u1eabn \u0111o\u00e1n nguy\u00ean nh\u00e2n<\/strong><\/p>\n<p><strong><em>3.2.1. Mi\u1ec3n d\u1ecbch<\/em><\/strong><\/p>\n<p>\u0110\u1ecbnh l\u01b0\u1ee3ng kh\u00e1ng th\u1ec3 thyroglobulin ( AbTg) v\u00e0\/ho\u1eb7c thyroperoxidase(AbTPO ) , kh\u00e1ng th\u1ec3 th\u1ee5 th\u1ec3 TSH ( \u1ee9c ch\u1ebf ) ( TSH-R Ab <sub>block<\/sub>).<\/p>\n<p><strong><em>3.2.2. TSH <\/em><\/strong><\/p>\n<p>Thay \u0111\u1ed5i n\u1ed3ng \u0111\u1ed9 TSH gi\u00fap \u0111\u1ecbnh v\u1ecb tr\u00ed th\u01b0\u01a1ng t\u1ed5n ti\u00ean ph\u00e1t hay th\u1ee9 ph\u00e1t. TSH l\u00e0 x\u00e9t nghi\u1ec7m \u0111\u1ec3 g\u1ee3i \u00fd ch\u1ea9n \u0111o\u00e1n gi\u1ea3m ho\u1ea1t gi\u00e1p.\u00a0 \u0110\u1ecbnh l\u01b0\u1ee3ng TSH b\u1eb1ng k\u1ef9 thu\u1eadt mi\u1ec5n d\u1ecbch th\u1ebf h\u1ec7 th\u1ee9 3 cho ph\u00e9p \u0111\u1ecbnh l\u01b0\u1ee3ng TSH \u1edf n\u1ed3ng \u0111\u1ed9 d\u01b0\u1edbi 0,01 mU\/ ml. N\u1ed3ng \u0111\u1ed9 TSH b\u00ecnh th\u01b0\u1eddng 0,4- 4 mU\/ ml, c\u00f3 th\u1ec3 t\u0103ng \u0111\u1ebfn 5 -10mU\/ml trong gi\u1ea3m ho\u1ea1t\u00a0 gi\u00e1p giai \u0111o\u1ea1n ti\u1ec1n l\u00e2m s\u00e0ng, n\u1ebfu tr\u00ean 10 mU\/ml\u00a0 l\u00e0 ch\u1eafc ch\u1eafn . N\u1ed3ng \u0111\u1ed9 TSH t\u01b0\u01a1ng quan ngh\u1ecbch v\u1edbi n\u1ed3ng \u0111\u1ed9 FT<sub>4<\/sub> h\u01a1n l\u00e0 FT<sub>3<\/sub><\/p>\n<p><strong><em>3.2.3. Test TRH<\/em><\/strong><\/p>\n<p>Hi\u1ec7n nay d\u00f9ng \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n gi\u1ea3m ho\u1ea1t gi\u00e1p trung \u01b0\u01a1ng (tuy\u1ebfn y\u00ean, d\u01b0\u1edbi \u0111\u1ed3i) \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 FT<sub>4<\/sub> th\u1ea5p v\u00e0 TSH b\u00ecnh th\u01b0\u1eddng; ho\u1eb7c \u0111\u1ec3 ph\u00e2n bi\u1ec7t nguy\u00ean nh\u00e2n do tuy\u1ebfn y\u00ean hay do d\u01b0\u1edbi \u0111\u1ed3i.<\/p>\n<p><strong>3.3. X\u00e9t nghi\u1ec7m v\u1ec1 h\u00ecnh \u1ea3nh <\/strong><\/p>\n<p><strong><em>3.3.1. <a href=\"https:\/\/www.vinmec.com\/vi\/tin-tuc\/thong-tin-suc-khoe\/suc-khoe-tong-quat\/muc-dich-cua-sieu-am-tuyen-giap\/\">Si\u00eau \u00e2m gi\u00e1p<\/a><\/em><\/strong><\/p>\n<p>Gi\u00fap ph\u00e1t hi\u1ec7n h\u00ecnh \u1ea3nh \u0111\u1ea1i th\u1ec3 b\u1ec7nh l\u00fd tuy\u1ebfn gi\u00e1p li\u00ean quan .<\/p>\n<p><strong><em>3.3.2. Ch\u1ee5p nh\u1ea5p nh\u00e1y ph\u00f3ng x\u1ea1 b\u1eb1ng I131, I123 hay Tc99m <\/em><\/strong><\/p>\n<p>Bi\u1ec3u hi\u1ec7n ho\u1ea1t t\u00ednh ph\u00f3ng x\u1ea1 ph\u00e2n b\u1ed1 c\u1ee7a b\u1ec7nh tuy\u1ebfn gi\u00e1p li\u00ean quan .<\/p>\n<p><strong><em>3.3.3.H\u00ecnh \u1ea3nh c\u1ecdng h\u01b0\u1edfng t\u1eeb (IRM) tuy\u1ebfn y\u00ean <\/em><\/strong><\/p>\n<p>Ph\u00e1t hi\u1ec7n u tuy\u1ebfn y\u00ean. L\u01b0u \u00fd trong nguy\u00ean nh\u00e2n gi\u1ea3m ho\u1ea1t gi\u00e1p ti\u00ean ph\u00e1t k\u00e9o d\u00e0i \u1edf ng\u01b0\u1eddi tr\u1ebb, l\u00e0m tuy\u1ebfn y\u00ean l\u1edbn ra v\u00e0 th\u1eadm ch\u00ed \u0103n m\u00f2n h\u1ed1 y\u00ean nh\u01b0 1 tr\u01b0\u1eddng h\u1ee3p u tuy\u1ebfn y\u00ean th\u1eadt s\u1ef1.<\/p>\n<p><strong>3.4. C\u00e1c x\u00e9t nghi\u1ec7m gi\u00e1n ti\u1ebfp kh\u00e1c<\/strong><\/p>\n<p>&#8211; Huy\u1ebft h\u1ecdc: thi\u1ebfu m\u00e1u \u0111\u1eb3ng s\u1eafc, h\u1ed3ng c\u1ea7u nh\u1ecf do thi\u1ebfu s\u1eaft (do ch\u1ea3y m\u00e1u, thi\u1ebfu d\u1ecbch v\u1ecb), h\u1ed3ng c\u1ea7u to (do thi\u1ebfu folat v\u00e0 vitamin B12).<\/p>\n<p>&#8211; T\u0103ng cholesterol to\u00e0n ph\u1ea7n trong \u0111\u00f3 t\u0103ng IDL v\u00e0 LDL cholesterol<\/p>\n<p>T\u0103ng cholesterol m\u00e1u \u0111\u01a1n thu\u1ea7n (typ IIa) 56%; ph\u1ed1i h\u1ee3p t\u0103ng triglycerid (type IIb) 34%, t\u0103ng triglycerid \u0111\u01a1n thu\u1ea7n 1,5%.<\/p>\n<p>&#8211; Gi\u1ea3m natri m\u00e1u do ho\u00e0 lo\u00e3ng k\u00e8m th\u1ea3i natri c\u00f2n \u0111\u1ea3m b\u1ea3o.<\/p>\n<h2><strong>4. Ch\u1ea9n \u0111o\u00e1n h\u1ed9i ch\u1ee9ng gi\u1ea3m ho\u1ea1t gi\u00e1p<\/strong><\/h2>\n<p>Giai \u0111o\u1ea1n l\u00e2m s\u00e0ng \u0111i\u1ec3n h\u00ecnh th\u01b0\u1eddng l\u00e0 qu\u00e1 mu\u1ed9n v\u1edbi c\u00e1c d\u1ea5u ch\u1ee9ng v\u00e0 bi\u1ebfn ch\u1ee9ng c\u1ee7a thi\u1ebfu hormone gi\u00e1p n\u1eb7ng v\u00e0 k\u00e9o d\u00e0i .<\/p>\n<p><strong>4.1. L\u00e2m s\u00e0ng<\/strong><\/p>\n<p>Ch\u1ee7 y\u1ebfu d\u1ef1a v\u00e0o:<\/p>\n<p>&#8211; H\u1ed9i ch\u1ee9ng da, ni\u00eam m\u1ea1c<\/p>\n<p>&#8211; H\u1ed9i ch\u1ee9ng gi\u1ea3m chuy\u1ec3n h\u00f3a: m\u1ec7t m\u1ecfi, ng\u1ee7 li b\u00ec, s\u1ee3 l\u1ea1nh, r\u1ed1i lo\u1ea1n tr\u00ed nh\u1edb, t\u0103ng c\u00e2n, ch\u00e1n \u0103n<\/p>\n<p>+ Kh\u00f4ng s\u1edd \u0111\u01b0\u1ee3c tuy\u1ebfn gi\u00e1p (vi\u00eam teo tuy\u1ebfn gi\u00e1p m\u1ea1n t\u00ednh).<\/p>\n<p>+ Tuy\u1ebfn gi\u00e1p lan t\u1ecfa trong vi\u00eam tuy\u1ebfn gi\u00e1p sau sinh v\u00e0 Hashimoto.<\/p>\n<p>+ Lan t\u1ecfa \u0111\u00e0n h\u1ed3i trong gi\u1ea3m ho\u1ea1t tuy\u1ebfn gi\u00e1p do iode v\u00e0 r\u1ed1i lo\u1ea1n t\u1ed5ng h\u1ee3p hormon.<\/p>\n<p><strong>4.2. C\u1eadn l\u00e2m s\u00e0ng:<\/strong> FT4 gi\u1ea3m , FT3 gi\u1ea3m , TSH c\u1ef1c nh\u1ea1y t\u0103ng (nguy\u00ean ph\u00e1t ) ho\u1eb7c gi\u1ea3m ( th\u1ee9 ph\u00e1t ).<\/p>\n<ol start=\"5\">\n<li>Ch\u1ea9n \u0111o\u00e1n gi\u00e1n bi\u1ec7t<\/li>\n<\/ol>\n<p><strong>5.1. H\u1ed9i ch\u1ee9ng Down<\/strong><\/p>\n<p>M\u1eaft x\u1ebfch, kh\u00f4ng c\u00f3 b\u01b0\u1edbu l\u1edbn.<\/p>\n<p><strong>5.2. H\u1ed9i ch\u1ee9ng th\u1eadn h\u01b0 <\/strong><\/p>\n<p>Ph\u00f9 m\u1ec1m, tr\u1eafng, l\u00f5m; n\u01b0\u00f3c ti\u1ec3u c\u00f3 protein ni\u1ec7u cao &gt;3,5 g\/24 gi\u1edd, protein m\u00e1u gi\u1ea3m.<\/p>\n<p><strong>5.3. Suy tu\u1ea7n ho\u00e0n n\u00e3o \u1edf ng\u01b0\u1eddi gi\u00e0<\/strong><\/p>\n<p>Gi\u1ea3m tr\u00ed nh\u1edb, \u0111\u00f4i l\u00fac bu\u1ed3n r\u1ea7u, \u00edt n\u00f3i, \u00edt \u01b0a ti\u1ebfp x\u00fac, da b\u1ea1c, d\u1ec5 l\u1ea1nh. FT3, FT4 b\u00ecnh th\u01b0\u1eddng.<\/p>\n<p><strong>5.4. Suy th\u1eadn m\u1ea1n<\/strong><\/p>\n<p>Thi\u1ebfu m\u00e1u, ure m\u00e1u v\u00e0 creatinin m\u00e1u cao, t\u0103ng huy\u1ebft \u00e1p.<\/p>\n<p><strong>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/strong><\/p>\n<ol>\n<li><em> N\u1ed9i ti\u1ebft h\u1ecdc \u0111\u1ea1i c\u01b0\u01a1ng. Mai Th\u1ebf Tr\u1ea1ch, Nguy\u1ec5n Thy Khu\u00ea. NXB TP H\u1ed3 Ch\u00ed Minh. 1999.<\/em><\/li>\n<li><em> Williams Textbook of Endocrinology. 9<sup>th<\/sup> Edition. W.B. Saunders Company. 1998.<\/em><\/li>\n<li><em> Endocrinology. 4<sup>th<\/sup> Edition. W.B. Saunders Company. 2001.<\/em><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>H\u1ed9i ch\u1ee9ng gi\u1ea3m ho\u1ea1t gi\u00e1p l\u00e0 nh\u1eefng bi\u1ec3u hi\u1ec7n l\u00e2m s\u00e0ng v\u00e0 c\u1eadn l\u00e2m s\u00e0ng c\u1ee7a c\u00e1c c\u01a1 quan \u0111\u00edch c\u1ee7a c\u01a1 th\u1ec3 x\u1ea3y ra do gi\u1ea3m s\u1ea3n xu\u1ea5t v\u00e0\/ho\u1eb7c gi\u1ea3m t\u00e1c d\u1ee5ng hormon gi\u00e1p. N\u1ebfu kh\u00f4ng nh\u1eadn bi\u1ebft s\u1edbm v\u00e0 \u0111i\u1ec1u tr\u1ecb, suy gi\u00e1p c\u00f3 th\u1ec3 d\u1eabn t\u1edbi c\u00e1c bi\u1ebfn ch\u1ee9ng nghi\u00eam tr\u1ecdng. 1. [&hellip;]<\/p>\n","protected":false},"author":16,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[80,33],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Ti\u1ebfp c\u1eadn h\u1ed9i ch\u1ee9ng gi\u1ea3m ho\u1ea1t gi\u00e1p - Vinmec<\/title>\n<meta name=\"description\" content=\"H\u1ed9i ch\u1ee9ng gi\u1ea3m ho\u1ea1t gi\u00e1p l\u00e0 nh\u1eefng bi\u1ec3u hi\u1ec7n l\u00e2m s\u00e0ng v\u00e0 c\u1eadn l\u00e2m s\u00e0ng c\u1ee7a c\u00e1c c\u01a1 quan \u0111\u00edch c\u1ee7a c\u01a1 th\u1ec3 x\u00e3y ra do gi\u1ea3m s\u1ea3n xu\u1ea5t hormon gi\u00e1p.\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ti\u1ebfp c\u1eadn h\u1ed9i ch\u1ee9ng gi\u1ea3m ho\u1ea1t gi\u00e1p - Vinmec\" \/>\n<meta property=\"og:description\" content=\"H\u1ed9i ch\u1ee9ng gi\u1ea3m ho\u1ea1t gi\u00e1p l\u00e0 nh\u1eefng bi\u1ec3u hi\u1ec7n l\u00e2m s\u00e0ng v\u00e0 c\u1eadn l\u00e2m s\u00e0ng c\u1ee7a c\u00e1c c\u01a1 quan \u0111\u00edch c\u1ee7a c\u01a1 th\u1ec3 x\u00e3y ra do gi\u1ea3m s\u1ea3n xu\u1ea5t hormon gi\u00e1p.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/05\/03\/tiep-can-hoi-chung-giam-hoat-giap\/\" \/>\n<meta property=\"og:site_name\" content=\"Vinmec\" \/>\n<meta property=\"article:published_time\" content=\"2023-05-03T07:55:27+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/20190831_110307_198495_hormon-thyroxin.max-800x800-1-300x212.jpg\" \/>\n<meta name=\"author\" content=\"Dai Tran Van\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Dai Tran Van\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"8 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/05\/03\/tiep-can-hoi-chung-giam-hoat-giap\/\",\"url\":\"https:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/05\/03\/tiep-can-hoi-chung-giam-hoat-giap\/\",\"name\":\"Ti\u1ebfp c\u1eadn h\u1ed9i ch\u1ee9ng gi\u1ea3m ho\u1ea1t gi\u00e1p - 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