{"id":29993,"date":"2023-06-22T15:07:19","date_gmt":"2023-06-22T08:07:19","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=29993"},"modified":"2023-06-22T15:07:19","modified_gmt":"2023-06-22T08:07:19","slug":"thuc-pham-chua-vitamin-k-anh-huong-den-warfarin-nhu-the-nao","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/06\/22\/thuc-pham-chua-vitamin-k-anh-huong-den-warfarin-nhu-the-nao\/","title":{"rendered":"Th\u1ef1c ph\u1ea9m ch\u1ee9a vitamin K \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn Warfarin nh\u01b0 th\u1ebf n\u00e0o?"},"content":{"rendered":"<p><strong>Warfarin l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 ng\u0103n ng\u1eeba v\u00e0 \u0111i\u1ec1u tr\u1ecb \u0111\u00f4ng m\u00e1u trong c\u00e1c b\u1ec7nh nh\u00e2n m\u1eafc c\u00e1c b\u1ec7nh tim m\u1ea1ch ho\u1eb7c \u0111\u1ed9t qu\u1ef5. Tuy nhi\u00ean, khi s\u1eed d\u1ee5ng Warfarin, c\u1ea7n ph\u1ea3i h\u1ea1n ch\u1ebf m\u1ed9t s\u1ed1 lo\u1ea1i th\u1ef1c ph\u1ea9m ch\u1ee9a vitamin K, b\u1edfi v\u00ec vitamin K l\u00e0 ch\u1ea5t gi\u00fap \u0111\u00f4ng m\u00e1u v\u00e0 c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a Warfarin. Do \u0111\u00f3, vi\u1ec7c hi\u1ec3u r\u00f5 v\u1ec1 nh\u1eefng th\u1ef1c ph\u1ea9m ch\u1ee9a vitamin K s\u1ebd gi\u00fap cho b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng Warfarin c\u00f3 th\u1ec3 \u0111i\u1ec1u ch\u1ec9nh ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng v\u00e0 \u0111\u1ea3m b\u1ea3o hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb c\u1ee7a thu\u1ed1c<\/strong><\/p>\n<h2><strong>1.T\u00ecm hi\u1ec3u chung\u00a0<\/strong><\/h2>\n<h3><span style=\"font-weight: 400;\">1.1 S\u01a1 l\u01b0\u1ee3c v\u1ec1 vitamin K<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">\u201cVitamin K\u201d t\u00ean chung c\u1ee7a m\u1ed9t h\u1ecd c\u00e1c h\u1ee3p ch\u1ea5t c\u00f3 c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc ph\u1ed5 bi\u1ebfn l\u00e0 2-metyl-1,4-naphthoquinone v\u00e0 l\u00e0 m\u1ed9t lo\u1ea1i vitamin tan trong ch\u1ea5t b\u00e9o c\u00f3 t\u1ef1 nhi\u00ean trong m\u1ed9t s\u1ed1 lo\u1ea1i th\u1ef1c ph\u1ea9m v\u00e0 c\u00f3 s\u1eb5n d\u01b0\u1edbi d\u1ea1ng th\u1ef1c ph\u1ea9m b\u1ed5 sung. Nh\u1eefng h\u1ee3p ch\u1ea5t n\u00e0y bao g\u1ed3m phylloquinone (vitamin K1) v\u00e0 menaquinone (vitamin K2). Phylloquinone hi\u1ec7n di\u1ec7n ch\u1ee7 y\u1ebfu trong c\u00e1c lo\u1ea1i rau l\u00e1 xanh v\u00e0 l\u00e0 d\u1ea1ng vitamin K ch\u00ednh trong ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng, Menaquinones, ch\u1ee7 y\u1ebfu c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb vi khu\u1ea9n v\u00e0 ch\u1ec9 v\u1edbi s\u1ed1 l\u01b0\u1ee3ng \u00edt trong c\u00e1c lo\u1ea1i th\u1ef1c ph\u1ea9m l\u00ean men v\u00e0 c\u00f3 ngu\u1ed3n g\u1ed1c \u0111\u1ed9ng v\u1eadt kh\u00e1c nhau<\/span><\/p>\n<figure id=\"attachment_30250\" aria-describedby=\"caption-attachment-30250\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-30250\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/Vitamin-K-300x250.png\" alt=\"Vitamin K\" width=\"300\" height=\"250\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/Vitamin-K-300x250.png 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/Vitamin-K.png 368w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-30250\" class=\"wp-caption-text\">Vitamin K<\/figcaption><\/figure>\n<p><span style=\"font-weight: 400;\">Vitamin K c\u00f3 ch\u1ee9c n\u0103ng nh\u01b0 m\u1ed9t coenzyme cho carboxylase, m\u1ed9t lo\u1ea1i enzyme c\u1ea7n thi\u1ebft cho qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p protein li\u00ean quan \u0111\u1ebfn qu\u00e1 tr\u00ecnh c\u1ea7m m\u00e1u (\u0111\u00f4ng m\u00e1u) v\u00e0 chuy\u1ec3n h\u00f3a x\u01b0\u01a1ng. Trong \u0111\u00f3, Prothrombin (y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u II) l\u00e0 m\u1ed9t protein ph\u1ee5 thu\u1ed9c v\u00e0o vitamin K trong huy\u1ebft t\u01b0\u01a1ng c\u00f3 li\u00ean quan tr\u1ef1c ti\u1ebfp \u0111\u1ebfn qu\u00e1 tr\u00ecnh \u0111\u00f4ng m\u00e1u<\/span><\/p>\n<p><span style=\"font-weight: 400;\">C\u00e1c khuy\u1ebfn ngh\u1ecb v\u1ec1 l\u01b0\u1ee3ng vitamin K v\u00e0 c\u00e1c ch\u1ea5t dinh d\u01b0\u1ee1ng kh\u00e1c \u0111\u01b0\u1ee3c cung c\u1ea5p trong kh\u1ea9u ph\u1ea7n tham kh\u1ea3o c\u1ee7a ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng (DRIs) \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n b\u1edfi Ban Th\u1ef1c ph\u1ea9m v\u00e0 Dinh d\u01b0\u1ee1ng (FNB) t\u1ea1i Vi\u1ec7n Y h\u1ecdc c\u1ee7a H\u1ecdc vi\u1ec7n Qu\u1ed1c gia. Trong \u0111\u00f3, l\u01b0\u1ee3ng h\u1ea5p th\u1ee5 \u0111\u1ea7y \u0111\u1ee7 (AI) \u0111\u1ed1i v\u1edbi vitamin K \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o nh\u01b0 sau\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tr\u1ebb s\u01a1 sinh &lt; 6 th\u00e1ng: 2mcg cho c\u1ea3 nam v\u00e0 n\u1eef\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">7 \u2013 12 th\u00e1ng: 2,5 mcg cho c\u1ea3 nam v\u00e0 n\u1eef\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">1 \u2013 3 tu\u1ed5i: 30mcg cho c\u1ea3 nam v\u00e0 n\u1eef\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">4 \u2013 8 tu\u1ed5i: 55mcg cho c\u1ea3 nam v\u00e0 n\u1eef<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">9 \u2013 13 tu\u1ed5i: 60mcg cho c\u1ea3 nam v\u00e0 n\u1eef\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">14 \u2013 18 tu\u1ed5i: 75mcg cho c\u1ea3 nam v\u00e0 n\u1eef\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">19 tu\u1ed5i tr\u1edf l\u00ean: 120mcg cho nam v\u00e0 90mcg cho n\u1eef\u00a0<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">1.2 T\u1ed5ng quan v\u1ec1 thu\u1ed1c Warfarin<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Ch\u1ec9 \u0111\u1ecbnh: <a href=\"https:\/\/www.vinmec.com\/vi\/thuoc\/warfarin-145\/\">Warfarin<\/a> l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c n\u1eb1m trong nh\u00f3m thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u v\u00e0 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong d\u1ef1 ph\u00f2ng v\u00e0 \u0111i\u1ec1u tr\u1ecb huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch v\u00e0 c\u00e1c bi\u1ebfn c\u1ed1 thuy\u00ean t\u1eafc huy\u1ebft kh\u1ed1i. Warfarin s\u1eed d\u1ee5ng l\u00e2m s\u00e0ng \u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p: (1) D\u1ef1 ph\u00f2ng v\u00e0 \u0111i\u1ec1u tr\u1ecb huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch v\u00e0 thuy\u00ean t\u1eafc ph\u1ed5i ph\u00e1t sinh, (2) D\u1ef1 ph\u00f2ng v\u00e0 \u0111i\u1ec1u tr\u1ecb bi\u1ebfn ch\u1ee9ng thuy\u00ean t\u1eafc huy\u1ebft kh\u1ed1i do rung nh\u0129 ho\u1eb7c thay van tim, (3) Gi\u1ea3m nguy c\u01a1 t\u1eed vong, nh\u1ed3i m\u00e1u c\u01a1 tim t\u00e1i ph\u00e1t v\u00e0 c\u00e1c bi\u1ebfn c\u1ed1 thuy\u00ean t\u1eafc huy\u1ebft kh\u1ed1i (\u0111\u1ed9t qu\u1ef5) sau nh\u1ed3i m\u00e1u c\u01a1 tim<\/span><\/p>\n<figure id=\"attachment_30251\" aria-describedby=\"caption-attachment-30251\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-30251\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/Warfarin-300x300.png\" alt=\"Warfarin\" width=\"300\" height=\"300\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/Warfarin-300x300.png 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/Warfarin-150x150.png 150w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/Warfarin.png 463w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-30251\" class=\"wp-caption-text\">Warfarin<\/figcaption><\/figure>\n<p><span style=\"font-weight: 400;\">C\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng: Warfarin \u1ee9c ch\u1ebf c\u1ea1nh tranh ph\u1ee9c h\u1ee3p vitamin K epoxide reductase 1 (VKORC1), m\u1ed9t lo\u1ea1i enzyme thi\u1ebft y\u1ebfu \u0111\u1ec3 k\u00edch ho\u1ea1t vitamin K c\u00f3 s\u1eb5n trong c\u01a1 th\u1ec3. T\u1eeb \u0111\u00f3, Warfarin l\u00e0m gi\u1ea3m qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p c\u00e1c y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u II, VII, IX v\u00e0 X \u1edf gan c\u0169ng nh\u01b0 c\u00e1c y\u1ebfu t\u1ed1 \u0111i\u1ec1u h\u00f2a \u0111\u00f4ng m\u00e1u protein C v\u00e0 protein S<\/span><\/p>\n<p><span style=\"font-weight: 400;\">D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a thu\u1ed1c: Warfarin \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng d\u01b0\u1edbi d\u1ea1ng \u0111\u01b0\u1eddng u\u1ed1ng<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">H\u1ea5p thu: Warfarin h\u1ea5p thu nhanh v\u00e0 ho\u00e0n to\u00e0n\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ph\u00e2n b\u1ed1: Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 nh\u1ecf (Vd = 0,14L\/kg) v\u00e0 thu\u1ed1c li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 99%<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Chuy\u1ec3n h\u00f3a: Warfarin chuy\u1ec3n h\u00f3a \u1edf gan ch\u1ee7 y\u1ebfu th\u00f4ng qua enzyme CYP2C9 v\u00e0 m\u1ed9t ph\u1ea7n chuy\u1ec3n h\u00f3a qua c\u00e1c enzyme CYP2C8, CYP2C19, CYP1A2, CYP3A4<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Th\u1ea3i tr\u1eeb: Warfarin \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu d\u01b0\u1edbi d\u1ea1ng c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a b\u1eb1ng c\u00e1ch l\u1ecdc qua c\u1ea7u th\u1eadn v\u1edbi th\u1eddi gian b\u00e1n h\u1ee7y t\u1eeb 20 \u2013 60 gi\u1edd\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">T\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng c\u1ee7a Warfarin bao g\u1ed3m ch\u1ea3y m\u00e1u v\u00e0 xu\u1ea5t huy\u1ebft nghi\u00eam tr\u1ecdng (xu\u1ea5t huy\u1ebft n\u1ed9i s\u1ecd, xu\u1ea5t huy\u1ebft ti\u00eau h\u00f3a, n\u00f4n ra m\u00e1u, xu\u1ea5t huy\u1ebft kh\u1edbp,&#8230;) c\u00f3 th\u1ec3 x\u1ea3y ra \u1edf h\u1ea7u h\u1ebft m\u1ecdi v\u1ecb tr\u00ed tr\u00ean c\u01a1 th\u1ec3. C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 ph\u1ed5 bi\u1ebfn kh\u00e1c bao g\u1ed3m bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au b\u1ee5ng, ch\u01b0\u1edbng b\u1ee5ng, \u0111\u1ea7y h\u01a1i v\u00e0 thay \u0111\u1ed5i v\u1ecb gi\u00e1c. C\u00e1c tr\u01b0\u1eddng h\u1ee3p hi\u1ebfm g\u1eb7p: h\u1ed9i ch\u1ee9ng ng\u00f3n ch\u00e2n t\u00edm, ho\u1ea1i t\u1eed da<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Warfarin c\u00f3 m\u1ed9t s\u1ed1 ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh v\u00e0 c\u00e2n nh\u1eafc l\u00e2m s\u00e0ng khi s\u1eed d\u1ee5ng \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n: qu\u00e1 m\u1eabn, c\u01a1 th\u1ec3 d\u1ec5 xu\u1ea5t huy\u1ebft, d\u1ecda s\u1ea3y thai, s\u1ea3n gi\u1eadt ho\u1eb7c ti\u1ec1n s\u1ea3n gi\u1eadt, mang thai, t\u0103ng huy\u1ebft \u00e1p \u00e1c t\u00ednh, g\u00e2y t\u00ea v\u00f9ng kh\u1ed1i th\u1eaft l\u01b0ng, ch\u1ecdc d\u00f2 t\u1ee7y s\u1ed1ng<\/span><\/p>\n<h2><strong>2.Th\u1ef1c ph\u1ea9m ch\u1ee9a vitamin K \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn Warfarin<\/strong><\/h2>\n<h3><span style=\"font-weight: 400;\">2.1 C\u00e1c <a href=\"https:\/\/www.vinmec.com\/vi\/tin-tuc\/thong-tin-suc-khoe\/nhung-thuc-pham-giau-vitamin-k\/\">th\u1ef1c ph\u1ea9m ch\u1ee9a vitamin K<\/a><\/span><\/h3>\n<figure id=\"attachment_30249\" aria-describedby=\"caption-attachment-30249\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-30249\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/Thuc-pham-chua-vitamin-K-300x264.jpg\" alt=\"Th\u1ef1c ph\u1ea9m ch\u1ee9a vitamin K\" width=\"300\" height=\"264\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/Thuc-pham-chua-vitamin-K-300x264.jpg 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/Thuc-pham-chua-vitamin-K-768x676.jpg 768w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/Thuc-pham-chua-vitamin-K.jpg 1000w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-30249\" class=\"wp-caption-text\">Th\u1ef1c ph\u1ea9m ch\u1ee9a vitamin K<\/figcaption><\/figure>\n<table>\n<tbody>\n<tr>\n<td><b>Vitamin K r\u1ea5t cao\u00a0<\/b><\/p>\n<p><b>(&gt; 100mcg\/kh\u1ea9u ph\u1ea7n)<\/b><\/td>\n<td><b>Vitamin K cao\u00a0<\/b><\/p>\n<p><b>(25 \u2013 100mcg\/kh\u1ea9u ph\u1ea7n)<\/b><\/td>\n<td><b>Vitamin K th\u1ea5p\u00a0<\/b><\/p>\n<p><b>(&lt; 25mcg\/kh\u1ea9u ph\u1ea7n)<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">C\u1ea3i xo\u0103n s\u1ed1ng \/ n\u1ea5u ch\u00edn<\/span><\/td>\n<td><span style=\"font-weight: 400;\">B\u1eafp c\u1ea3i s\u1ed1ng<\/span><\/td>\n<td><span style=\"font-weight: 400;\">C\u00e0 r\u1ed1t<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Rau bina s\u1ed1ng \/ n\u1ea5u ch\u00edn<\/span><\/td>\n<td><span style=\"font-weight: 400;\">H\u00fang qu\u1ebf kh\u00f4\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Chu\u1ed1i<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">B\u00f4ng c\u1ea3i xanh n\u1ea5u ch\u00edn\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Rau di\u1ebfp kh\u00f4<\/span><\/td>\n<td><span style=\"font-weight: 400;\">H\u1ea1t \u0111i\u1ec1u\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">C\u1ee7 c\u1ea3i xanh n\u1ea5u ch\u00edn\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Qu\u1ea3 kiwi<\/span><\/td>\n<td><span style=\"font-weight: 400;\">N\u1ea5m tr\u1eafng\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">C\u1ea3i Brussels n\u1ea5u ch\u00edn\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">\u0110\u1eadu xanh n\u1ea5u ch\u00edn\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">D\u01b0a chu\u1ed9t\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Rau m\u00f9i t\u00e2y t\u01b0\u01a1i<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Mayonnaise<\/span><\/td>\n<td><span style=\"font-weight: 400;\">\u1edat chu\u00f4ng s\u1ed1ng<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">B\u01a1 th\u1ef1c v\u1eadt<\/span><\/td>\n<td><span style=\"font-weight: 400;\">C\u00e1 ng\u1eeb<\/span><\/td>\n<td><span style=\"font-weight: 400;\">C\u1ea7n t\u00e2y<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">X\u00e0 l\u00e1ch tr\u1ed9n\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">M\u0103ng t\u00e2y\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">B\u00ed ng\u00f2i\u00a0<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400;\">2.2 Th\u1ef1c ph\u1ea9m v\u00e0 \u0111\u1ed3 u\u1ed1ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn Warfarin<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">R\u01b0\u1ee3u bia: R\u01b0\u1ee3u c\u00f3 th\u1ec3 thay \u0111\u1ed5i c\u00e1ch ho\u1ea1t \u0111\u1ed9ng c\u1ee7a Warfarin trong c\u01a1 th\u1ec3 n\u00ean c\u1ea7n gi\u1ea3m ho\u1eb7c tr\u00e1nh s\u1eed d\u1ee5ng r\u01b0\u1ee3u khi \u0111ang d\u00f9ng Warfarin. Khi say r\u01b0\u1ee3u c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Warfarin v\u00e0 l\u00e0m t\u0103ng ch\u1ec9 s\u1ed1 INR, t\u1eeb \u0111\u00f3 l\u00e0m nguy c\u01a1 b\u1ecb ch\u1ea3y m\u00e1u cao h\u01a1n<\/span><\/p>\n<p><span style=\"font-weight: 400;\">N\u01b0\u1edbc \u00e9p nam vi\u1ec7t qu\u1ea5t: M\u1eb7c d\u00f9 n\u01b0\u1edbc \u00e9p nam vi\u1ec7t qu\u1ea5t ch\u1ee9a \u00edt vitamin K nh\u01b0ng v\u1eabn c\u00f3 th\u1ec3 t\u01b0\u01a1ng t\u00e1c v\u1edbi Warfarin. M\u1ed9t s\u1ed1 b\u00e1o c\u00e1o tr\u01b0\u1eddng h\u1ee3p cho th\u1ea5y u\u1ed1ng m\u1ed9t l\u01b0\u1ee3ng l\u1edbn n\u01b0\u1edbc \u00e9p nam vi\u1ec7t qu\u1ea5t l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u khi d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi Warfarin<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Tr\u00e0 xanh: Trong b\u00e1o c\u00e1o \u0111\u00e3 \u0111\u1ec1 c\u1eadp r\u1eb1ng s\u1ef1 t\u01b0\u01a1ng t\u00e1c gi\u1eefa Warfarin v\u00e0 tr\u00e0 xanh l\u00e0 do l\u01b0\u1ee3ng vitamin K trong m\u1ed9t l\u01b0\u1ee3ng l\u1edbn tr\u00e0 xanh<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Xo\u00e0i: Xo\u00e0i ch\u1ee9a m\u1ed9t th\u00e0nh ph\u1ea7n c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Warfarin trong c\u01a1 th\u1ec3 v\u00e0 t\u0103ng ch\u1ec9 s\u1ed1 INR<\/span><\/p>\n<h2><strong>3.V\u00ec sao ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ho\u1ea1t \u0111\u1ed9ng v\u00e0 li\u1ec1u l\u01b0\u1ee3ng s\u1eed d\u1ee5ng c\u1ee7a Warfarin<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">Ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn l\u01b0\u1ee3ng Warfarin. Nguy\u00ean nh\u00e2n do li\u1ec1u Warfarin d\u1ef1a tr\u00ean ch\u1ec9 s\u1ed1 x\u00e9t nghi\u1ec7m \u0111o t\u1ed1c \u0111\u1ed9 c\u1ee5c m\u00e1u \u0111\u00f4ng (INR). Khi s\u1eed d\u1ee5ng thu\u1ed1c Warfarin, b\u1ec7nh nh\u00e2n c\u1ea7n th\u01b0\u1eddng xuy\u00ean ki\u1ec3m tra m\u1ee9c INR. Nh\u1eefng thay \u0111\u1ed5i trong ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng c\u00f3 th\u1ec3 thay \u0111\u1ed5i INR ngay c\u1ea3 khi l\u01b0\u1ee3ng Warfarin kh\u00f4ng \u0111\u1ed5i. C\u1ee5 th\u1ec3 n\u1ebfu b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng nhi\u1ec1u vitamin K c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m INR<\/span><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Warfarin l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 ng\u0103n ng\u1eeba v\u00e0 \u0111i\u1ec1u tr\u1ecb \u0111\u00f4ng m\u00e1u trong c\u00e1c b\u1ec7nh nh\u00e2n m\u1eafc c\u00e1c b\u1ec7nh tim m\u1ea1ch ho\u1eb7c \u0111\u1ed9t qu\u1ef5. Tuy nhi\u00ean, khi s\u1eed d\u1ee5ng Warfarin, c\u1ea7n ph\u1ea3i h\u1ea1n ch\u1ebf m\u1ed9t s\u1ed1 lo\u1ea1i th\u1ef1c ph\u1ea9m ch\u1ee9a vitamin K, b\u1edfi v\u00ec vitamin K l\u00e0 ch\u1ea5t gi\u00fap \u0111\u00f4ng m\u00e1u [&hellip;]<\/p>\n","protected":false},"author":54,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[12],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Th\u1ef1c ph\u1ea9m ch\u1ee9a vitamin K \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn Warfarin nh\u01b0 th\u1ebf n\u00e0o?<\/title>\n<meta name=\"description\" content=\"Warfarin l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u hi\u1ec7u qu\u1ea3 trong \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh tim m\u1ea1ch v\u00e0 \u0111\u1ed9t qu\u1ef5, nh\u01b0ng th\u1ef1c ph\u1ea9m ch\u1ee9a vitamin K l\u00e0m gi\u1ea3m\" 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