{"id":29445,"date":"2023-04-29T18:44:29","date_gmt":"2023-04-29T11:44:29","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=29445"},"modified":"2023-05-03T14:16:10","modified_gmt":"2023-05-03T07:16:10","slug":"dieu-tri-ung-thu-bieu-mo-buong-trung","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/29\/dieu-tri-ung-thu-bieu-mo-buong-trung\/","title":{"rendered":"\u0110i\u1ec1u tr\u1ecb ung th\u01b0 bi\u1ec3u m\u00f4 bu\u1ed3ng tr\u1ee9ng"},"content":{"rendered":"

Ung th\u01b0 bu\u1ed3ng tr\u1ee9ng (UTBT) l\u00e0 m\u1ed9t trong nh\u1eefng ung th\u01b0 ph\u1ee5 khoa hay g\u1eb7p nh\u1ea5t v\u00e0 c\u0169ng l\u00e0 m\u1ed9t trong nh\u1eefng nguy\u00ean nh\u00e2n g\u00e2y t\u1eed vong nhi\u1ec1u nh\u1ea5t cho n\u1eef gi\u1edbi. Theo GLOBOCAN 2018, tr\u00ean th\u1ebf gi\u1edbi, UTBT \u0111\u1ee9ng h\u00e0ng th\u1ee9 t\u00e1m \u1edf ph\u1ee5 n\u1eef v\u1edbi t\u1ef7 l\u1ec7 m\u1edbi m\u1eafc 6,6\/100.000 d\u00e2n. B\u00e0i vi\u1ebft d\u01b0\u1edbi \u0111\u00e2y s\u1ebd h\u01b0\u1edbng d\u1eabn \u0111i\u1ec1u tr\u1ecb ung th\u01b0 bu\u1ed3ng tr\u1ee9ng c\u1ee5 th\u1ec3 l\u00e0 ung th\u01b0 bi\u1ec3u m\u00f4 bu\u1ed3ng tr\u1ee9ng<\/strong><\/p>\n

1. Nguy\u00ean t\u1eafc chung<\/h2>\n

T\u00f9y theo th\u1ec3 m\u00f4 b\u1ec7nh h\u1ecdc, giai \u0111o\u1ea1n b\u1ec7nh, tu\u1ed5i, t\u00ecnh tr\u1ea1ng b\u1ec7nh nh\u00e2n\u2026 \u0111\u1ec3 \u00e1p d\u1ee5ng c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb th\u00edch h\u1ee3p. \u0110i\u1ec1u tr\u1ecb \u0111a m\u00f4 th\u1ee9c bao g\u1ed3m ph\u1eabu thu\u1eadt, x\u1ea1 tr\u1ecb, ho\u00e1 tr\u1ecb, \u0111i\u1ec1u tr\u1ecb \u0111\u00edch, \u0111i\u1ec1u tr\u1ecb mi\u1ec5n d\u1ecbch \u2026<\/p>\n

2. \u0110i\u1ec1u tr\u1ecb c\u1ee5 th\u1ec3 \u0111\u1ed1i v\u1edbi ung th\u01b0 bi\u1ec3u m\u00f4 bu\u1ed3ng tr\u1ee9ng <\/strong><\/h2>\n

2.1 \u0110i\u1ec1u tr\u1ecb ph\u1eabu thu\u1eadt <\/strong><\/p>\n

Ph\u1eabu thu\u1eadt c\u00f3 vai tr\u00f2 r\u1ea5t quan tr\u1ecdng trong \u0111i\u1ec1u tr\u1ecb ung th\u01b0 bi\u1ec3u m\u00f4 bu\u1ed3ng tr\u1ee9ng.<\/p>\n

    \n
  • Ph\u1eabu thu\u1eadt sinh thi\u1ebft t\u1ee9c th\u00ec l\u00e0m m\u00f4 b\u1ec7nh h\u1ecdc ch\u1ea9n \u0111o\u00e1n x\u00e1c \u0111\u1ecbnh UTBT;<\/li>\n
  • \u0110\u00e1nh gi\u00e1 ch\u00ednh x\u00e1c giai \u0111o\u1ea1n b\u1ec7nh;<\/li>\n
  • Ph\u1eabu thu\u1eadt tri\u1ec7t \u0111\u1ec3 bao g\u1ed3m c\u1eaft t\u1eed cung to\u00e0n b\u1ed9, ph\u1ea7n ph\u1ee5 hai b\u00ean, m\u1ea1c n\u1ed1i l\u1edbn. Trong t\u00ecnh hu\u1ed1ng b\u1ec7nh \u0111\u00e3 lan tr\u00e0n th\u00ec ph\u1eabu thu\u1eadt l\u1ea5y t\u1ed1i \u0111a c\u00e1c t\u1ed5n th\u01b0\u01a1ng sao cho c\u00e1c t\u1ed5n th\u01b0\u01a1ng c\u00f2n l\u1ea1i c\u00f3 k\u00edch th\u01b0\u1edbc nh\u1ecf nh\u1ea5t, Trong ph\u1eabu thu\u1eadt c\u1ea7n ki\u1ec3m tra v\u00f2m ho\u00e0nh, to\u00e0n b\u1ed9 b\u1ec1 m\u1eb7t ph\u00fac m\u1ea1c, b\u1ec1 m\u1eb7t c\u00e1c c\u01a1 quan, h\u1ea1ch ch\u1eadu, h\u1ea1ch ch\u1ee7 b\u1ee5ng v\u00e0 sinh thi\u1ebft c\u00e1c t\u1ed5n th\u01b0\u01a1ng nghi ng\u1edd. D\u1ecbch r\u1eeda \u1ed5 b\u1ee5ng c\u1ea7n \u0111\u01b0\u1ee3c l\u1ea5y l\u00e0m x\u00e9t nghi\u1ec7m t\u00ecm t\u1ebf b\u00e0o \u00e1c t\u00ednh.<\/li>\n
  • \u0110\u1ed1i v\u1edbi giai \u0111o\u1ea1n IA<\/sub>, IB<\/sub>, m\u00f4 b\u1ec7nh h\u1ecdc lo\u1ea1i bi\u1ec7t h\u00f3a t\u1ed1t ho\u1eb7c trung b\u00ecnh th\u00ec ph\u1eabu thu\u1eadt tri\u1ec7t \u0111\u1ec3 \u0111\u01b0\u1ee3c xem l\u00e0 \u0111\u1ee7. \u0110\u1ed1i v\u1edbi c\u00e1c b\u1ec7nh nh\u00e2n tr\u1ebb c\u00f3 nhu c\u1ea7u sinh con v\u00e0 b\u1ec7nh \u1edf giai \u0111o\u1ea1n c\u00f2n khu tr\u00fa (IA<\/sub>, IB<\/sub>), \u0111\u1ed9 m\u00f4 h\u1ecdc th\u1ea5p (\u0111\u1ed9 I), c\u00f3 th\u1ec3 xem x\u00e9t ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb b\u1ea3o t\u1ed3n v\u1edbi ph\u1eabu thu\u1eadt gi\u1edbi h\u1ea1n ch\u1ec9 c\u1eaft ph\u1ea7n ph\u1ee5 b\u00ean t\u1ed5n th\u01b0\u01a1ng.<\/li>\n<\/ul>\n
    \"Ung
    Ung th\u01b0 bu\u1ed3ng tr\u1ee9ng<\/figcaption><\/figure>\n

    2.2 \u0110i\u1ec1u tr\u1ecb ho\u00e1 ch\u1ea5t <\/strong><\/p>\n

    Ho\u00e1 ch\u1ea5t \u0111\u00f3ng vai tr\u00f2 ng\u00e0y c\u00e0ng quan tr\u1ecdng nh\u1ea5t l\u00e0 t\u1eeb khi c\u00f3 c\u00e1c t\u00e1c nh\u00e2n m\u1edbi g\u00f3p ph\u1ea7n l\u1edbn c\u1ea3i thi\u1ec7n ti\u00ean l\u01b0\u1ee3ng b\u1ec7nh. C\u00e1c h\u00f3a ch\u1ea5t m\u1edbi c\u00f3 hi\u1ec7u qu\u1ea3 trong \u0111i\u1ec1u tr\u1ecb UTBT bao g\u1ed3m: c\u00e1c taxane (Paclitaxel, docetaxel), gemcitabine, lipo-doxorubicin, topotecan. \u0110\u00e2y l\u00e0 nh\u1eefng t\u00e1c nh\u00e2n g\u00e2y \u0111\u1ed9c t\u1ebf b\u00e0o, \u0111\u1eb7c bi\u1ec7t g\u00e2y \u0111\u1ed9c t\u1ee7y x\u01b0\u01a1ng, khi ph\u1ed1i h\u1ee3p 2 thu\u1ed1c tr\u1edf l\u00ean, n\u00ean theo d\u00f5i ch\u1eb7t ch\u1ebd sau truy\u1ec1n, d\u00f9ng c\u00e1c thu\u1ed1c h\u1ed7 tr\u1ee3 v\u00e0 s\u1eed d\u1ee5ng c\u00e1c thu\u1ed1c d\u1ef1 ph\u00f2ng h\u1ea1 b\u1ea1ch c\u1ea7u. \u0110i\u1ec1u tr\u1ecb h\u00f3a ch\u1ea5t c\u00f3 th\u1ec3 l\u00e0 t\u00e2n b\u1ed5 tr\u1ee3, b\u1ed5 tr\u1ee3 ho\u1eb7c gi\u1ea3m nh\u1eb9 cho giai \u0111o\u1ea1n di c\u0103n xa.<\/p>\n

    * C\u00e1c ph\u00e1c \u0111\u1ed3 h\u00f3a tr\u1ecb t\u00e2n b\u1ed5 tr\u1ee3 hay d\u00f9ng:<\/strong><\/p>\n

    Ph\u00e1c \u0111\u1ed3 Carboplatin – paclitaxel<\/strong><\/p>\n

    Carboplatin AUC 5-6, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; Paclitaxel 175mg\/m2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; chu k\u1ef3 21 ng\u00e0y.<\/p>\n

    Ph\u00e1c \u0111\u1ed3 Carboplatin – docetaxel<\/strong><\/p>\n

    Carboplatin AUC 5, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; Docetaxel 75mg\/m2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; chu k\u1ef3 21 ng\u00e0y.<\/p>\n

    * C\u00e1c ph\u00e1c \u0111\u1ed3 h\u00f3a tr\u1ecb b\u1ed5 tr\u1ee3 hay d\u00f9ng:<\/p>\n

      \n
    • Paclitaxel 175mg\/m2<\/sup> truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; Carboplatin AUC 5-6 truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; chu k\u1ef3 21 ng\u00e0y, 3-6 chu k\u1ef3.<\/li>\n
    • Paclitaxel 80mg\/m2<\/sup> truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 8, v\u00e0 15; Carboplatin AUC 5-6 truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; chu k\u1ef3 21 ng\u00e0y, 6 chu k\u1ef3.<\/li>\n
    • Paclitaxel 60mg\/m2<\/sup> truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; Carboplatin AUC 2 truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; h\u00e0ng tu\u1ea7n trong 18 tu\u1ea7n.<\/li>\n
    • Docetaxel 60-75mg\/m2<\/sup> truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; Carboplatin AUC 5-6 truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; chu k\u1ef3 21 ng\u00e0y, 3-6 chu k\u1ef3.<\/li>\n
    • Carboplatin AUC 5 truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; Pegylated liposomal doxorubicin 30mg\/m2<\/sup>; chu k\u1ef3 28 ng\u00e0y, 6 chu k\u1ef3.<\/li>\n<\/ul>\n

      * C\u00e1c ph\u00e1c \u0111\u1ed3 h\u00f3a tr\u1ecb th\u01b0\u1eddng d\u00f9ng giai \u0111o\u1ea1n di c\u0103n:<\/p>\n

      Ph\u00e1c \u0111\u1ed3 Carboplatin – cyclophosphamide<\/strong><\/p>\n

      Carboplatin 300mg\/m2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1;<\/p>\n

      Cyclophosphamide 600mg\/m2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, Chu k\u1ef3 21 ng\u00e0y.<\/p>\n

      Ph\u00e1c \u0111\u1ed3 CP<\/strong><\/p>\n

      Cisplatin 75mg\/m2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1;<\/p>\n

      Cyclophomide 600mg\/m2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; chu k\u1ef3 21 ng\u00e0y.<\/p>\n

      Ph\u00e1c \u0111\u1ed3 PAC\u00a0<\/strong><\/p>\n

      Cisplatin 50mg\/m2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; Doxorubicin 50mg\/m2<\/sup> da truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; Cyclophosphamide 750mg\/m2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 21 ng\u00e0y.<\/p>\n

      Ph\u00e1c \u0111\u1ed3 Carboplatin – paclitaxel: nh\u01b0 t\u00e2n b\u1ed5 tr\u1ee3 Ph\u00e1c \u0111\u1ed3 Carboplatin – docetaxel: nh\u01b0 t\u00e2n b\u1ed5 tr\u1ee3 Ph\u00e1c \u0111\u1ed3 PT<\/strong><\/p>\n

      Cisplatin 75mg\/m2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; Paclitaxel 175mg\/m2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; chu k\u1ef3 21 ng\u00e0y.<\/p>\n

      Ph\u00e1c \u0111\u1ed3 Carboplatin – paclitaxel<\/strong><\/p>\n

      Carboplatin 300mg\/m2 <\/sup>da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; Paclitaxel 175mg\/m2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; chu k\u1ef3 21 ng\u00e0y.<\/p>\n

      Ph\u00e1c \u0111\u1ed3 gemcitabine – carboplatin\u00a0<\/strong><\/p>\n

      Gemcitabine 1.000mg\/m2<\/sup> ti\u00eam t\u0129nh m\u1ea1ch ng\u00e0y 1 v\u00e0 8<\/p>\n

      Carboplatin AUC4, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; chu k\u1ef3 21 ng\u00e0y.<\/p>\n

      Ph\u00e1c \u0111\u1ed3 paclitaxel \u0111\u01a1n thu\u1ea7n<\/strong><\/p>\n

      Paclitaxel 175mg\/m2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; chu k\u1ef3 21 ng\u00e0y.<\/p>\n

      Ph\u00e1c \u0111\u1ed3 paclitaxel h\u00e0ng tu\u1ea7n <\/strong><\/p>\n

      Paclitaxel 80mg\/m2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1.<\/p>\n

      Ph\u00e1c \u0111\u1ed3 docetaxel \u0111\u01a1n thu\u1ea7n <\/strong><\/p>\n

      Docetaxel 100mg\/m2 <\/sup>da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1; chu k\u1ef3 21 ng\u00e0y.<\/p>\n

      Ph\u00e1c \u0111\u1ed3 topotecan\u00a0 <\/strong><\/p>\n

      Topotecan 1,5mg\/m2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch 30 ph\u00fat ng\u00e0y 1-5; chu k\u1ef3 21 ng\u00e0y.<\/p>\n

      Ph\u00e1c \u0111\u1ed3 etoposide u\u1ed1ng <\/strong><\/p>\n

      Etoposide 50mg\/m2<\/sup>, u\u1ed1ng t\u1eeb ng\u00e0y 1-21, chu k\u1ef3 28 ng\u00e0y.<\/p>\n

      Ph\u00e1c \u0111\u1ed3 liposomal doxorubicin<\/strong><\/p>\n

      D\u00f9ng trong tr\u01b0\u1eddng h\u1ee3p b\u1ec7nh dai d\u1eb3ng v\u1edbi ph\u00e1c \u0111\u1ed3 c\u00f3 cisplatin, t\u1ef7 l\u1ec7 \u0111\u00e1p \u1ee9ng kho\u1ea3ng 26%.<\/p>\n

      Liposomal doxorubicin 50mg\/m2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 28 ng\u00e0y.<\/p>\n

      2.3 \u0110i\u1ec1u tr\u1ecb \u0111\u00edch (Targeted therapy) <\/strong><\/p>\n

      Hi\u1ec7n nay, c\u00f3 nhi\u1ec1u ti\u1ebfn b\u1ed9 trong \u0111i\u1ec1u tr\u1ecb ung th\u01b0 bu\u1ed3ng tr\u1ee9ng, \u0111\u1eb7c bi\u1ec7t l\u00e0 li\u1ec7u ph\u00e1p nh\u1eafm tr\u00fang \u0111\u00edch. S\u1ef1 ra \u0111\u1eddi c\u1ee7a kh\u00e1ng th\u1ec3 \u0111\u01a1n d\u00f2ng t\u00e1c \u0111\u1ed9ng l\u00ean c\u00e1c ph\u00e2n t\u1eed tr\u00ean b\u1ec1 m\u1eb7t t\u1ebf b\u00e0o v\u00e0 c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf ph\u00e2n t\u1eed nh\u1ecf t\u00e1c \u0111\u1ed9ng b\u00ean trong t\u1ebf b\u00e0o ung th\u01b0 l\u00e0 m\u1ed9t ti\u1ebfn b\u1ed9 l\u1edbn trong \u0111i\u1ec1u tr\u1ecb b\u1ec7nh ung th\u01b0 n\u00f3i chung v\u00e0 ung th\u01b0 bu\u1ed3ng tr\u1ee9ng n\u00f3i ri\u00eang.<\/p>\n

      (1) Thu\u1ed1c \u1ee9c ch\u1ebf y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng n\u1ed9i m\u00f4 m\u1ea1ch m\u00e1u: Bevacizumab<\/p>\n

      Bevacizumab l\u00e0 kh\u00e1ng th\u1ec3 \u0111\u01a1n d\u00f2ng \u1ee9c ch\u1ebf y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng n\u1ed9i m\u00f4 m\u1ea1ch m\u00e1u VEGF (Vascular Endothelial Growth Factor). Bevacizumab c\u1ea3i thi\u1ec7n c\u00f3 \u00fd ngh\u0129a r\u00f5 r\u1ec7t khi ph\u1ed1i h\u1ee3p v\u1edbi h\u00f3a ch\u1ea5t ph\u00e1c \u0111\u1ed3 PC (Paclitaxel – Carboplatin) trong \u0111i\u1ec1u tr\u1ecb UTBT giai \u0111o\u1ea1n III, IV v\u00e0 UTBT c\u00f3 y\u1ebfu t\u1ed1 ti\u00ean l\u01b0\u1ee3ng x\u1ea5u, k\u00edch th\u01b0\u1edbc t\u1ed5n th\u01b0\u01a1ng t\u1ed3n d\u01b0 sau ph\u1eabu thu\u1eadt >1cm. Bevacizumab \u0111\u00e3 ch\u00ednh th\u1ee9c \u0111\u01b0\u1ee3c FDA M\u1ef9 ch\u1ea5p thu\u1eadn \u0111i\u1ec1u tr\u1ecb ung th\u01b0 bu\u1ed3ng tr\u1ee9ng t\u00e1i ph\u00e1t kh\u00e1ng v\u1edbi ph\u00e1c \u0111\u1ed3 c\u00f3 platinum t\u1eeb th\u00e1ng 11.2014.<\/p>\n

      * M\u1ed9t s\u1ed1 ph\u00e1c \u0111\u1ed3 h\u00f3a ch\u1ea5t k\u1ebft h\u1ee3p v\u1edbi bevacizumab:<\/strong><\/p>\n

      Ph\u00e1c \u0111\u1ed3 paclitaxel – carboplatin – bevacizumab<\/strong><\/p>\n

      Paclitaxel 175mg\/m2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch trong 3 gi\u1edd, ng\u00e0y 1<\/p>\n

      Carboplatin AUC 5-6, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n

      Bevacizumab 15mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch 30-90 ph\u00fat, ng\u00e0y 1<\/p>\n

      Chu k\u1ef3 3 tu\u1ea7n, 6 chu k\u1ef3. Bevacizumab ti\u1ebfp t\u1ee5c \u0111\u1ebfn \u0111\u1ee7 12 chu k\u1ef3.<\/p>\n

      * Ph\u00e1c \u0111\u1ed3 cho b\u1ec7nh t\u00e1i ph\u00e1t nh\u1ea1y platin<\/p>\n

      Ph\u00e1c \u0111\u1ed3 bevacizumab – carboplatin – gemcitabine<\/strong><\/p>\n

      Bevacizumab 15mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1.<\/p>\n

      Gemcitabine 1.000mg\/m2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1 v\u00e0 ng\u00e0y 8.<\/p>\n

      Carboplatin AUC 4, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1.<\/p>\n

      Chu k\u1ef3 3 tu\u1ea7n\/ l\u1ea7n, trong 6 \u0111\u1ebfn 10 li\u1ec7u tr\u00ecnh.<\/p>\n

      Ti\u1ebfp t\u1ee5c bevacizumab \u0111\u01a1n \u0111\u1ed9c (15mg\/kg) m\u1ed7i 3 tu\u1ea7n cho \u0111\u1ebfn khi b\u1ec7nh ti\u1ebfn tri\u1ec3n ho\u1eb7c kh\u00f4ng ch\u1ecbu \u0111\u01b0\u1ee3c \u0111\u1ed9c t\u00ednh c\u1ee7a thu\u1ed1c.<\/p>\n

      * Ph\u00e1c \u0111\u1ed3 cho b\u1ec7nh t\u00e1i ph\u00e1t kh\u00e1ng platin<\/strong><\/p>\n

      Ph\u00e1c \u0111\u1ed3 paclitaxel h\u00e0ng tu\u1ea7n – bevacizumab<\/strong><\/p>\n

      Paclitaxel 80mg\/m2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch h\u00e0ng tu\u1ea7n<\/p>\n

      Bevacizumab 10mg\/kg c\u00e2n n\u1eb7ng, truy\u1ec1n t\u0129nh m\u1ea1ch m\u1ed7i 2 tu\u1ea7n.<\/p>\n

      Ph\u00e1c \u0111\u1ed3 lipodoxorubicin – bevacizumab<\/strong><\/p>\n

      Lipodoxorubicin 50mg\/m2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch trong 30 ph\u00fat, m\u1ed7i 3 tu\u1ea7n Bevacizumab 10mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch m\u1ed7i 2 tu\u1ea7n.<\/p>\n

      Ph\u00e1c \u0111\u1ed3 topotecan – bevacizumab<\/strong><\/p>\n

      Topotecan 1,25-1,5mg\/m2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1-5, m\u1ed7i 3 tu\u1ea7n Bevacizumab 15mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch m\u1ed7i 3 tu\u1ea7n.<\/p>\n

      Ph\u00e1c \u0111\u1ed3 topotecan h\u00e0ng tu\u1ea7n – bevacizumab <\/strong>Topotecan 1,75mg\/m2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch h\u00e0ng tu\u1ea7n<\/p>\n

      Bevacizumab 10mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch m\u1ed7i 2 tu\u1ea7n.<\/p>\n

      Ph\u00e1c \u0111\u1ed3 docetaxel <\/strong><\/p>\n

      Docetaxel 75mg\/m2<\/sup> truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 21 ng\u00e0y<\/p>\n

      Ph\u00e1c \u0111\u1ed3 gemcitabine<\/strong><\/p>\n

      Gemcitabine 1000mg\/m2<\/sup> truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, ng\u00e0y 8, chu k\u1ef3 21 ng\u00e0y.<\/p>\n

      (2) Thu\u1ed1c \u1ee9c ch\u1ebf PARP (Poly ADP ribose polymerase)<\/p>\n

        \n
      • Olaparib\u066d<\/strong> l\u00e0 thu\u1ed1c \u1ee9c ch\u1ebf PARP, l\u00e0m \u1ee9c ch\u1ebf qu\u00e1 tr\u00ecnh s\u1eeda ch\u1eefa DNA, t\u1eeb \u0111\u00f3 g\u00e2y ch\u1ebft t\u1ebf b\u00e0o ung th\u01b0. Thu\u1ed1c n\u00e0y c\u00f3 ch\u1ec9 \u0111\u1ecbnh:<\/li>\n<\/ul>\n

        – \u0110i\u1ec1u tr\u1ecb duy tr\u00ec ung th\u01b0 bi\u1ec3u m\u00f4 bu\u1ed3ng tr\u1ee9ng \u0111\u1ed9 m\u00f4 h\u1ecdc cao, ung th\u01b0 \u1ed1ng d\u1eabn tr\u1ee9ng ho\u1eb7c ung th\u01b0 ph\u00fac m\u1ea1c nguy\u00ean ph\u00e1t \u1edf giai \u0111o\u1ea1n ti\u1ebfn xa (FIGO giai \u0111o\u1ea1n III v\u00e0 IV) v\u00e0 c\u00f3 \u0111\u1ed9t bi\u1ebfn gen BRCA1\/2<\/em> {d\u1ea1ng di truy\u1ec1n (germline) v\u00e0\/ho\u1eb7c d\u1ea1ng m\u1eafc ph\u1ea3i (somatic)}, \u0111ang c\u00f3 \u0111\u00e1p \u1ee9ng (ho\u00e0n to\u00e0n ho\u1eb7c m\u1ed9t ph\u1ea7n) sau khi ho\u00e0n t\u1ea5t h\u00f3a tr\u1ecb li\u1ec7u b\u01b0\u1edbc 1 c\u00f3 ch\u1ee9a platinum.<\/p>\n

        – \u0110i\u1ec1u tr\u1ecb duy tr\u00ec ung th\u01b0 bi\u1ec3u m\u00f4 bu\u1ed3ng tr\u1ee9ng \u0111\u1ed9 m\u00f4 h\u1ecdc cao, ung th\u01b0 \u1ed1ng d\u1eabn tr\u1ee9ng ho\u1eb7c ung th\u01b0 ph\u00fac m\u1ea1c nguy\u00ean ph\u00e1t v\u00e0 t\u00e1i ph\u00e1t nh\u1ea1y v\u1edbi platinum (platinum sensitive relapsed), \u0111ang c\u00f3 \u0111\u00e1p \u1ee9ng (ho\u00e0n to\u00e0n ho\u1eb7c m\u1ed9t ph\u1ea7n) v\u1edbi h\u00f3a tr\u1ecb li\u1ec7u c\u00f3 ch\u1ee9a platinum.<\/p>\n

        Li\u1ec1u d\u00f9ng: Thu\u1ed1c \u0111\u01b0\u1ee3c dung n\u1ea1p t\u1ed1t, c\u00f3 d\u1ea1ng b\u00e0o ch\u1ebf vi\u00ean n\u00e9n 100mg v\u00e0 150mg.\u00a0 2 vi\u00ean 150mg x 2 l\u1ea7n m\u1ed7i ng\u00e0y, t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi t\u1ed5ng li\u1ec1u h\u00e0ng ng\u00e0y l\u00e0 600mg. \u0110i\u1ec1u tr\u1ecb t\u1edbi khi b\u1ec7nh ti\u1ebfn tri\u1ec3n ho\u1eb7c t\u00f9y theo \u0111\u00e1nh gi\u00e1 c\u1ee7a b\u00e1c s\u0129 t\u1ea1i t\u1ea1i th\u1eddi \u0111i\u1ec3m 2 n\u0103m (\u0111\u1ed1i v\u1edbi b\u01b0\u1edbc 1 ung th\u01b0 bu\u1ed3ng tr\u1ee9ng giai \u0111o\u1ea1n ti\u1ebfn xa c\u00f3 \u0111\u1ed9t bi\u1ebfn BRCA).<\/p>\n

          \n
        • C\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf PARP th\u1ebf h\u1ec7 sau bao g\u1ed3m rucaparib\u066d<\/strong> v\u00e0 niraparib\u066d<\/strong> \u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn \u0111i\u1ec1u tr\u1ecb ung th\u01b0 bu\u1ed3ng tr\u1ee9ng ti\u1ebfn tri\u1ec3n sau \u0111i\u1ec1u tr\u1ecb.<\/li>\n<\/ul>\n

          – Rucaparib\u066d<\/strong> ch\u1ec9 \u0111\u1ecbnh ung th\u01b0 bu\u1ed3ng tr\u1ee9ng t\u00e1i ph\u00e1t c\u00f3 \u0111\u1ed9t bi\u1ebfn BRCA, li\u1ec1u d\u00f9ng 600mg, u\u1ed1ng 2 l\u1ea7n\/ng\u00e0y.<\/p>\n

          – Niraparib\u066d \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb ung th\u01b0 bu\u1ed3ng tr\u1ee9ng (lo\u1ea1i nh\u1ea1y c\u1ea3m v\u1edbi platinum tr\u01b0\u1edbc \u0111\u00f3) sau th\u1ea5t b\u1ea1i v\u1edbi \u00edt nh\u1ea5t 2 b\u01b0\u1edbc \u0111i\u1ec1u tr\u1ecb ho\u00e1 ch\u1ea5t. Li\u1ec1u d\u00f9ng 300mg u\u1ed1ng h\u00e0ng ng\u00e0y.<\/p>\n

          2.4 Li\u1ec7u ph\u00e1p n\u1ed9i ti\u1ebft <\/strong><\/p>\n

          Li\u1ec7u ph\u00e1p n\u1ed9i ti\u1ebft t\u1ed1 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c xem x\u00e9t cho nh\u1eefng b\u1ec7nh nh\u00e2n t\u00e1i ph\u00e1t kh\u00f4ng c\u00f3 tri\u1ec7u ch\u1ee9ng ho\u1eb7c b\u1ec7nh nh\u00e2n c\u1ea7n ngh\u1ec9 h\u00f3a tr\u1ecb li\u1ec7u.<\/p>\n

          Tamoxifen 20mg hai l\u1ea7n\/ng\u00e0y, u\u1ed1ng h\u00e0ng ng\u00e0y<\/p>\n

          Letrozole 2,5mg u\u1ed1ng h\u00e0ng ng\u00e0y<\/p>\n

          2.5 \u0110i\u1ec1u tr\u1ecb mi\u1ec5n d\u1ecbch\u00a0 <\/strong><\/p>\n

          \u0110i\u1ec1u tr\u1ecb mi\u1ec5n d\u1ecbch \u0111ang n\u1edf r\u1ed9 mang l\u1ea1i nhi\u1ec1u h\u1ee9a h\u1eb9n cho b\u1ec7nh nh\u00e2n ung th\u01b0 n\u00f3i chung, trong \u0111\u00f3 c\u00f3 ung th\u01b0 bu\u1ed3ng tr\u1ee9ng. C\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng v\u1edbi pembrolizumab, atezolizumab \u0111ang \u0111\u01b0\u1ee3c ti\u1ebfn h\u00e0nh mang l\u1ea1i nh\u1eefng k\u1ebft qu\u1ea3 kh\u1ea3 quan ban \u0111\u1ea7u.<\/p>\n

          2.6 \u0110i\u1ec1u tr\u1ecb mi\u1ec5n d\u1ecbch ph\u00f3ng x\u1ea1 (Radioimmunotherapy – RIT) <\/strong><\/p>\n

          Hi\u1ec7n c\u00e1c kh\u00e1ng th\u1ec3 \u0111\u01a1n d\u00f2ng g\u1eafn \u0111\u1ed3ng v\u1ecb ph\u00f3ng x\u1ea1 \u0111ang \u0111\u01b0\u1ee3c th\u1eed nghi\u1ec7m v\u1edbi hy v\u1ecdng m\u1edf ra m\u1ed9t k\u1ef7 nguy\u00ean m\u1edbi cho b\u1ec7nh nh\u00e2n ung th\u01b0 bu\u1ed3ng tr\u1ee9ng giai \u0111o\u1ea1n mu\u1ed9n, ph\u1ea3i k\u1ec3 \u0111\u1ebfn HMFG (human milk fat globule) g\u1eafn 90<\/sup>Y, Hu2PLAP (Placental-like alkaline phosphatase) g\u1eafn 111<\/sup>In, 123<\/sup>I, Trastuzumab (kh\u00e1ng th\u1ec3 kh\u00e1ng HER2) g\u1eafn 90<\/sup>Y, Pertuzumab (kh\u00e1ng th\u1ec3 kh\u00e1ng m\u1ed9t domain c\u1ee7a Her-2\/neu) g\u1eafn 177<\/sup>Lu, OC125 (kh\u00e1ng th\u1ec3 kh\u00e1ng kh\u00e1ng nguy\u00ean CA 125 trong ung th\u01b0 bu\u1ed3ng tr\u1ee9ng) g\u1eafn 90<\/sup>Y. g. X\u1ea1 tr\u1ecb <\/em><\/p>\n

          \u00cdt \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng trong ung th\u01b0 bu\u1ed3ng tr\u1ee9ng, bao g\u1ed3m x\u1ea1 tr\u1ecb h\u1eadu ph\u1eabu c\u00e1c b\u1ec7nh nh\u00e2n giai \u0111o\u1ea1n I, x\u1ea1 tr\u1ecb cho nh\u1eefng b\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u00e1p \u1ee9ng v\u1edbi ho\u00e1 ch\u1ea5t, ho\u1eb7c \u0111i\u1ec1u tr\u1ecb v\u1edbt v\u00e1t.<\/p>\n

          C\u00f3 th\u1ec3 \u00e1p d\u1ee5ng x\u1ea1 tr\u1ecb gi\u1ea3m nh\u1eb9 to\u00e0n \u1ed5 b\u1ee5ng trong UTBT giai \u0111o\u1ea1n mu\u1ed9n, UTBT t\u00e1i ph\u00e1t lan tr\u00e0n \u1ed5 b\u1ee5ng. C\u00f3 th\u1ec3 x\u1ea1 tr\u1ecb b\u1eb1ng m\u00e1y Cobalt – 60, m\u00e1y x\u1ea1 tr\u1ecb gia t\u1ed1c, m\u00e1y x\u1ea1 tr\u1ecb proton. Li\u1ec1u x\u1ea1 44Gy.<\/p>\n

          X\u1ea1 tr\u1ecb to\u00e0n n\u00e3o trong UTBT di c\u0103n n\u00e3o \u0111a \u1ed5 (>3 \u1ed5), li\u1ec1u x\u1ea1 40-45Gy, 2Gy\/ng\u00e0y ho\u1eb7c 30Gy, 3Gy\/ng\u00e0y c\u00f3 th\u1ec3 ph\u1ed1i h\u1ee3p v\u1edbi dao gamma.<\/p>\n

          2.7 X\u1ea1 ph\u1eabu b\u1eb1ng dao gamma, dao gamma quay <\/strong><\/p>\n

          R\u1ea5t c\u00f3 x\u1ea1 gi\u00e1 tr\u1ecb trong vi\u1ec7c ki\u1ec3m so\u00e1t UTBT di c\u0103n n\u00e3o t\u1eeb 1-3 \u1ed5, k\u00edch th\u01b0\u1edbc d\u01b0\u1edbi 3cm. T\u1ef7 l\u1ec7 ki\u1ec3m so\u00e1t t\u1ea1i n\u00e3o \u0111\u1ea1t 90%. Li\u1ec1u x\u1ea1 ph\u1eabu 18-26Gy.<\/p>\n","protected":false},"excerpt":{"rendered":"

          Ung th\u01b0 bu\u1ed3ng tr\u1ee9ng (UTBT) l\u00e0 m\u1ed9t trong nh\u1eefng ung th\u01b0 ph\u1ee5 khoa hay g\u1eb7p nh\u1ea5t v\u00e0 c\u0169ng l\u00e0 m\u1ed9t trong nh\u1eefng nguy\u00ean nh\u00e2n g\u00e2y t\u1eed vong nhi\u1ec1u nh\u1ea5t cho n\u1eef gi\u1edbi. Theo GLOBOCAN 2018, tr\u00ean th\u1ebf gi\u1edbi, UTBT \u0111\u1ee9ng h\u00e0ng th\u1ee9 t\u00e1m \u1edf ph\u1ee5 n\u1eef v\u1edbi t\u1ef7 l\u1ec7 m\u1edbi m\u1eafc 6,6\/100.000 d\u00e2n. B\u00e0i vi\u1ebft […]<\/p>\n","protected":false},"author":49,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[13,33],"tags":[],"yoast_head":"\n\u0110i\u1ec1u tr\u1ecb ung th\u01b0 bi\u1ec3u m\u00f4 bu\u1ed3ng tr\u1ee9ng - Vinmec<\/title>\n<meta name=\"description\" content=\"\u0110i\u1ec1u tr\u1ecb ung th\u01b0 bu\u1ed3ng tr\u1ee9ng bao g\u1ed3m c\u00e1c ph\u01b0\u01a1ng ph\u00e1p sau: \u0111i\u1ec1u tr\u1ecb ph\u1eabu thu\u1eadt, ho\u00e1 ch\u1ea5t, \u0111i\u1ec1u tr\u1ecb \u0111\u00edch, b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u0110i\u1ec1u tr\u1ecb ung th\u01b0 bi\u1ec3u m\u00f4 bu\u1ed3ng tr\u1ee9ng - Vinmec\" \/>\n<meta property=\"og:description\" content=\"\u0110i\u1ec1u tr\u1ecb ung th\u01b0 bu\u1ed3ng tr\u1ee9ng bao g\u1ed3m c\u00e1c ph\u01b0\u01a1ng ph\u00e1p sau: \u0111i\u1ec1u tr\u1ecb ph\u1eabu thu\u1eadt, ho\u00e1 ch\u1ea5t, \u0111i\u1ec1u tr\u1ecb \u0111\u00edch, b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch\" \/>\n<meta property=\"og:url\" content=\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/29\/dieu-tri-ung-thu-bieu-mo-buong-trung\/\" \/>\n<meta property=\"og:site_name\" content=\"Vinmec\" \/>\n<meta property=\"article:published_time\" content=\"2023-04-29T11:44:29+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-05-03T07:16:10+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Thiet-ke-chua-co-ten-18-300x300.png\" \/>\n<meta name=\"author\" content=\"Yen Cao Thi\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Yen Cao Thi\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"10 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/29\/dieu-tri-ung-thu-bieu-mo-buong-trung\/\",\"url\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/29\/dieu-tri-ung-thu-bieu-mo-buong-trung\/\",\"name\":\"\u0110i\u1ec1u tr\u1ecb ung th\u01b0 bi\u1ec3u m\u00f4 bu\u1ed3ng tr\u1ee9ng - Vinmec\",\"isPartOf\":{\"@id\":\"https:\/\/noithathoaphat.in\/ctv\/#website\"},\"datePublished\":\"2023-04-29T11:44:29+00:00\",\"dateModified\":\"2023-05-03T07:16:10+00:00\",\"author\":{\"@id\":\"https:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/23b59e05279f2010cef262423cbff684\"},\"description\":\"\u0110i\u1ec1u tr\u1ecb ung th\u01b0 bu\u1ed3ng tr\u1ee9ng bao g\u1ed3m c\u00e1c ph\u01b0\u01a1ng ph\u00e1p sau: \u0111i\u1ec1u tr\u1ecb ph\u1eabu thu\u1eadt, ho\u00e1 ch\u1ea5t, \u0111i\u1ec1u tr\u1ecb \u0111\u00edch, b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch\",\"breadcrumb\":{\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/29\/dieu-tri-ung-thu-bieu-mo-buong-trung\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/29\/dieu-tri-ung-thu-bieu-mo-buong-trung\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/29\/dieu-tri-ung-thu-bieu-mo-buong-trung\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/noithathoaphat.in\/ctv\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"\u0110i\u1ec1u tr\u1ecb ung th\u01b0 bi\u1ec3u m\u00f4 bu\u1ed3ng tr\u1ee9ng\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/noithathoaphat.in\/ctv\/#website\",\"url\":\"https:\/\/noithathoaphat.in\/ctv\/\",\"name\":\"Vinmec\",\"description\":\"H\u1ec7 th\u1ed1ng Y t\u1ebf Vinmec\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/noithathoaphat.in\/ctv\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/23b59e05279f2010cef262423cbff684\",\"name\":\"Yen Cao Thi\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/image\/\",\"url\":\"http:\/\/0.gravatar.com\/avatar\/062c89c69b65ec7b29ef712b8d1bcd62?s=96&d=mm&r=g\",\"contentUrl\":\"http:\/\/0.gravatar.com\/avatar\/062c89c69b65ec7b29ef712b8d1bcd62?s=96&d=mm&r=g\",\"caption\":\"Yen Cao Thi\"},\"url\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/author\/caothiyen-workinggmail-com\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"\u0110i\u1ec1u tr\u1ecb ung th\u01b0 bi\u1ec3u m\u00f4 bu\u1ed3ng tr\u1ee9ng - Vinmec","description":"\u0110i\u1ec1u tr\u1ecb ung th\u01b0 bu\u1ed3ng tr\u1ee9ng bao g\u1ed3m c\u00e1c ph\u01b0\u01a1ng ph\u00e1p sau: \u0111i\u1ec1u tr\u1ecb ph\u1eabu thu\u1eadt, ho\u00e1 ch\u1ea5t, \u0111i\u1ec1u tr\u1ecb \u0111\u00edch, b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch","robots":{"index":"noindex","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"og_locale":"en_US","og_type":"article","og_title":"\u0110i\u1ec1u tr\u1ecb ung th\u01b0 bi\u1ec3u m\u00f4 bu\u1ed3ng tr\u1ee9ng - Vinmec","og_description":"\u0110i\u1ec1u tr\u1ecb ung th\u01b0 bu\u1ed3ng tr\u1ee9ng bao g\u1ed3m c\u00e1c ph\u01b0\u01a1ng ph\u00e1p sau: \u0111i\u1ec1u tr\u1ecb ph\u1eabu thu\u1eadt, ho\u00e1 ch\u1ea5t, \u0111i\u1ec1u tr\u1ecb \u0111\u00edch, b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch","og_url":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/29\/dieu-tri-ung-thu-bieu-mo-buong-trung\/","og_site_name":"Vinmec","article_published_time":"2023-04-29T11:44:29+00:00","article_modified_time":"2023-05-03T07:16:10+00:00","og_image":[{"url":"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Thiet-ke-chua-co-ten-18-300x300.png"}],"author":"Yen Cao Thi","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Yen Cao Thi","Est. reading time":"10 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/29\/dieu-tri-ung-thu-bieu-mo-buong-trung\/","url":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/29\/dieu-tri-ung-thu-bieu-mo-buong-trung\/","name":"\u0110i\u1ec1u tr\u1ecb ung th\u01b0 bi\u1ec3u m\u00f4 bu\u1ed3ng tr\u1ee9ng - Vinmec","isPartOf":{"@id":"https:\/\/noithathoaphat.in\/ctv\/#website"},"datePublished":"2023-04-29T11:44:29+00:00","dateModified":"2023-05-03T07:16:10+00:00","author":{"@id":"https:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/23b59e05279f2010cef262423cbff684"},"description":"\u0110i\u1ec1u tr\u1ecb ung th\u01b0 bu\u1ed3ng tr\u1ee9ng bao g\u1ed3m c\u00e1c ph\u01b0\u01a1ng ph\u00e1p sau: \u0111i\u1ec1u tr\u1ecb ph\u1eabu thu\u1eadt, ho\u00e1 ch\u1ea5t, \u0111i\u1ec1u tr\u1ecb \u0111\u00edch, b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch","breadcrumb":{"@id":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/29\/dieu-tri-ung-thu-bieu-mo-buong-trung\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/29\/dieu-tri-ung-thu-bieu-mo-buong-trung\/"]}]},{"@type":"BreadcrumbList","@id":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/29\/dieu-tri-ung-thu-bieu-mo-buong-trung\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/noithathoaphat.in\/ctv\/"},{"@type":"ListItem","position":2,"name":"\u0110i\u1ec1u tr\u1ecb ung th\u01b0 bi\u1ec3u m\u00f4 bu\u1ed3ng tr\u1ee9ng"}]},{"@type":"WebSite","@id":"https:\/\/noithathoaphat.in\/ctv\/#website","url":"https:\/\/noithathoaphat.in\/ctv\/","name":"Vinmec","description":"H\u1ec7 th\u1ed1ng Y t\u1ebf Vinmec","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/noithathoaphat.in\/ctv\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/23b59e05279f2010cef262423cbff684","name":"Yen Cao Thi","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/image\/","url":"http:\/\/0.gravatar.com\/avatar\/062c89c69b65ec7b29ef712b8d1bcd62?s=96&d=mm&r=g","contentUrl":"http:\/\/0.gravatar.com\/avatar\/062c89c69b65ec7b29ef712b8d1bcd62?s=96&d=mm&r=g","caption":"Yen Cao Thi"},"url":"http:\/\/noithathoaphat.in\/ctv\/index.php\/author\/caothiyen-workinggmail-com\/"}]}},"_links":{"self":[{"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/posts\/29445"}],"collection":[{"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/users\/49"}],"replies":[{"embeddable":true,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/comments?post=29445"}],"version-history":[{"count":6,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/posts\/29445\/revisions"}],"predecessor-version":[{"id":31050,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/posts\/29445\/revisions\/31050"}],"wp:attachment":[{"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/media?parent=29445"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/categories?post=29445"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/tags?post=29445"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}