{"id":29326,"date":"2023-04-29T17:04:51","date_gmt":"2023-04-29T10:04:51","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=29326"},"modified":"2023-04-29T17:04:51","modified_gmt":"2023-04-29T10:04:51","slug":"dieu-tri-ung-thu-vu-giai-doan-muon-tai-phat-di-can","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/29\/dieu-tri-ung-thu-vu-giai-doan-muon-tai-phat-di-can\/","title":{"rendered":"\u0110i\u1ec1u tr\u1ecb ung th\u01b0 v\u00fa giai \u0111o\u1ea1n mu\u1ed9n, t\u00e1i ph\u00e1t, di c\u0103n"},"content":{"rendered":"<p><strong>Ung th\u01b0 v\u00fa (UTV) l\u00e0 lo\u1ea1i ung th\u01b0 th\u01b0\u1eddng g\u1eb7p v\u00e0 l\u00e0 nguy\u00ean nh\u00e2n g\u00e2y t\u1eed vong h\u00e0ng \u0111\u1ea7u do ung th\u01b0 \u1edf ph\u1ee5 n\u1eef tr\u00ean to\u00e0n th\u1ebf gi\u1edbi. M\u1ed7i n\u0103m n\u01b0\u1edbc ta c\u00f3 kho\u1ea3ng h\u01a1n 15.230 ph\u1ee5 n\u1eef m\u1edbi m\u1eafc v\u00e0 h\u01a1n 6.100 ng\u01b0\u1eddi t\u1eed vong do UTV. Ung th\u01b0 v\u00fa nam chi\u1ebfm kho\u1ea3ng 1% c\u00e1c tr\u01b0\u1eddng h\u1ee3p UTV. Vi\u1ec7c s\u1eed d\u1ee5ng m\u1ed9t hay nhi\u1ec1u ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u00eau tr\u00ean c\u0103n c\u1ee9 v\u00e0o giai \u0111o\u1ea1n v\u00e0 c\u00e1c y\u1ebfu t\u1ed1 b\u1ec7nh h\u1ecdc tr\u00ean t\u1eebng b\u1ec7nh nh\u00e2n c\u1ee5 th\u1ec3. B\u00e0i vi\u1ebft d\u01b0\u1edbi d\u00e2y s\u1ebd h<\/strong><strong>\u01b0\u1edbng d\u1eabn \u0111i\u1ec1u tr\u1ecb <a href=\"https:\/\/www.vinmec.com\/vi\/ung-buou-xa-tri\/thong-tin-suc-khoe\/nhung-thong-tin-can-biet-truoc-khi-quyet-dinh-dieu-tri-ung-thu\/\">ung th\u01b0 v\u00fa<\/a> giai \u0111o\u1ea1n mu\u1ed9n, t\u00e1i ph\u00e1t, di c\u0103n<\/strong><\/p>\n<h2><strong>1. \u0110i\u1ec1u tr\u1ecb n\u1ed9i ti\u1ebft v\u00e0 \u0111i\u1ec1u tr\u1ecb \u0111\u00edch ung th\u01b0 v\u00fa giai \u0111o\u1ea1n mu\u1ed9n, t\u00e1i ph\u00e1t, di c\u0103n <\/strong><\/h2>\n<p>&nbsp;<\/p>\n<figure id=\"attachment_28348\" aria-describedby=\"caption-attachment-28348\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-28348\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/ty-le-chua-khoi-ung-thu-vu-bao-nhieu-phan-tram-1-300x200.png\" alt=\"Ung th\u01b0 v\u00fa\" width=\"300\" height=\"200\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/ty-le-chua-khoi-ung-thu-vu-bao-nhieu-phan-tram-1-300x200.png 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/ty-le-chua-khoi-ung-thu-vu-bao-nhieu-phan-tram-1-768x512.png 768w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/ty-le-chua-khoi-ung-thu-vu-bao-nhieu-phan-tram-1.png 800w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-28348\" class=\"wp-caption-text\">Ung th\u01b0 v\u00fa<\/figcaption><\/figure>\n<h2>1.1 Th\u1ee5 th\u1ec3 n\u1ed9i ti\u1ebft d\u01b0\u01a1ng t\u00ednh, HER2 \u00e2m t\u00ednh trong ung th\u01b0 v\u00fa<\/h2>\n<p><strong><em>a. Ph\u1ee5 n\u1eef ch\u01b0a m\u00e3n kinh <\/em><\/strong><\/p>\n<ul>\n<li>Tr\u01b0\u1eddng h\u1ee3p \u0111ang d\u00f9ng ho\u1eb7c \u0111\u00e3 ng\u1eebng thu\u1ed1c n\u1ed9i ti\u1ebft d\u01b0\u1edbi 1 n\u0103m: C\u1eaft bu\u1ed3ng tr\u1ee9ng ho\u1eb7c \u1ee9c ch\u1ebf bu\u1ed3ng tr\u1ee9ng b\u1eb1ng ch\u1ea5t \u0111\u1ed3ng v\u1eadn GnRH + thu\u1ed1c n\u1ed9i ti\u1ebft (\u00b1 \u1ee9c ch\u1ebf CDK4\/6 (ribociclib) ho\u1eb7c \u1ee9c ch\u1ebf mTOR (Everolimus) nh\u01b0 \u0111i\u1ec1u tr\u1ecb ph\u1ee5 n\u1eef \u0111\u00e3 m\u00e3n kinh.<\/li>\n<li>Tr\u01a3\u1eddng h\u1ee3p kh\u00f4ng d\u00f9ng thu\u1ed1c n\u1ed9i ti\u1ebft h\u01a1n 1 n\u0103m: C\u1eaft bu\u1ed3ng tr\u1ee9ng ho\u1eb7c \u1ee9c ch\u1ebf bu\u1ed3ng tr\u1ee9ng b\u1eb1ng ch\u1ea5t \u0111\u1ed3ng v\u1eadn GnRH + thu\u1ed1c n\u1ed9i ti\u1ebft (\u00b1 \u1ee9c ch\u1ebf CDK4\/6 (ribociclib) ho\u1eb7c \u1ee9c ch\u1ebf mTOR) nh\u01a3 \u0111i\u1ec1u tr\u1ecb ph\u1ee5 n\u1eef \u0111\u00e3 m\u00e3n kinh, ho\u1eb7c d\u00f9ng thu\u1ed1c \u0111i\u1ec1u h\u00f2a th\u1ee5 th\u1ec3 ER ch\u1ecdn l\u1ecdc (SERM) nh\u01b0 tamoxifen.<\/li>\n<li>Li\u1ec1u d\u00f9ng: Ribociclib 600mg\/ng\u00e0y x 3 tu\u1ea7n, ngh\u1ec9 1 tu\u1ea7n cho \u0111\u1ebfn khi b\u1ec7nh ti\u1ebfn tri\u1ec3n.<\/li>\n<\/ul>\n<p><strong>b. <em>Ph\u1ee5 n\u1eef \u0111\u00e3 m\u00e3n kinh <\/em><\/strong><\/p>\n<h4>C\u00e1c ph\u00e1c \u0111\u1ed3 \u01b0u ti\u00ean<\/h4>\n<ul>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf aromatase + \u1ee9c ch\u1ebf CDK 4\/6 (ribociclib)<\/li>\n<\/ul>\n<p>Li\u1ec1u d\u00f9ng: Ribociclib 600mg\/ng\u00e0y x 3 tu\u1ea7n, ngh\u1ec9 1 tu\u1ea7n cho \u0111\u1ebfn khi b\u1ec7nh ti\u1ebfn tri\u1ec3n.<\/p>\n<ul>\n<li>Fulvestrant + \u1ee9c ch\u1ebf CDK 4\/6 (ribociclib)<\/li>\n<li>Fulvestrant + \u1ee9c ch\u1ebf PI3K v\u1edbi c\u00e1c tr\u01a3\u1eddng h\u1ee3p \u0111\u1ed9t bi\u1ebfn PIK3CA (alpelisib)<\/li>\n<li>Thu\u1ed1c gi\u00e1ng h\u00f3a ER ch\u1ecdn l\u1ecdc (fulvestrant)<\/li>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf aromatase kh\u00f4ng steroid (anastrozole, letrozole)<\/li>\n<li>Thu\u1ed1c \u0111i\u1ec1u bi\u1ebfn ER ch\u1ecdn l\u1ecdc (tamoxifen)<\/li>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf aromatase steroid (exemestane)<\/li>\n<li>Exemestane + everolimus<\/li>\n<li>Fulvestrant + everolimus<\/li>\n<li>Fulvestrant + anastrozole -Tamoxifen + everolimus<\/li>\n<\/ul>\n<h4>C\u00e1c ph\u00e1c \u0111\u1ed3 kh\u00e1c<\/h4>\n<ul>\n<li>Ethinyl estradiol<\/li>\n<\/ul>\n<h2>1.2 Th\u1ee5 th\u1ec3 n\u1ed9i ti\u1ebft d\u01b0\u01a1ng t\u00ednh, HER2 d\u01b0\u01a1ng t\u00ednh<\/h2>\n<ul>\n<li>\u0110i\u1ec1u tr\u1ecb n\u1ed9i ti\u1ebft + kh\u00e1ng HER2 (\u1ee8c ch\u1ebf aromatase + trastuzumab, \u1ee9c ch\u1ebf aromatase + lapatinib, \u1ee9c ch\u1ebf aromatase + trastuzumab \u00b1 lapatinib, fulvestrant + trastuzumab, tamoxifen + trastuzumab .v.v.)<\/li>\n<li>Ho\u1eb7c \u0111i\u1ec1u tr\u1ecb n\u1ed9i ti\u1ebft \u0111\u01a1n thu\u1ea7n (kh\u00f4ng k\u1ebft h\u1ee3p thu\u1ed1c \u0111\u00edch).<\/li>\n<\/ul>\n<p>C\u00f3 th\u1ec3 s\u1eed d\u1ee5ng c\u00e1c ph\u00e1c \u0111\u1ed3 nh\u01b0 trong m\u1ee5c \u0111i<strong><em>\u00a0Th\u1ee5 th\u1ec3 n\u1ed9i ti\u1ebft d\u01b0\u01a1ng t\u00ednh, HER2 \u00e2m t\u00ednh <\/em><\/strong>\u1edf b\u1ec7nh nh\u00e2n HER2 d\u01b0\u01a1ng t\u00ednh nh\u01b0ng kh\u00f4ng c\u00f3 \u0111i\u1ec1u ki\u1ec7n ho\u1eb7c ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng c\u00e1c thu\u1ed1c kh\u00e1ng HER2.<\/p>\n<h2><strong>2. H\u00f3a tr\u1ecb v\u00e0 \u0111i\u1ec1u tr\u1ecb \u0111\u00edch ung th\u01b0 v\u00fa giai \u0111o\u1ea1n mu\u1ed9n, t\u00e1i ph\u00e1t, di c\u0103n <\/strong><\/h2>\n<p><strong>2.1. HER2 \u00e2m t\u00ednh<\/strong><\/p>\n<p><strong>2.1.1 Ph\u00e1c \u0111\u1ed3 \u0111\u01a1n ch\u1ea5t<\/strong><\/p>\n<h4>C\u00e1c ph\u00e1c \u0111\u1ed3 \u01b0u ti\u00ean<\/h4>\n<p>&#8211; Anthracyclines: doxorubicin, liposomal doxorubicin<\/p>\n<p>+ Doxorubicin 60-75 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1. Chu k\u1ef3 21 ng\u00e0y<\/p>\n<p>+ Doxorubicin 20 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 7 ng\u00e0y<\/p>\n<p>liposomal doxorubicin 50 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 28 ng\u00e0y. &#8211; Taxane: paclitaxel<\/p>\n<p>+ Paclitaxel 175 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 21 ng\u00e0y.<\/p>\n<p>+ Paclitaxel 80 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 7 ng\u00e0y. &#8211; Nh\u00f3m thu\u1ed1c ch\u1ed1ng chuy\u1ec3n h\u00f3a: capecitabine, gemcitabine<\/p>\n<p>+ Capecitabine 1000-1250 mg\/m<sup>2<\/sup>, u\u1ed1ng ng\u00e0y 2 l\u1ea7n, t\u1eeb ng\u00e0y 1-14. Chu k\u1ef3 21 ng\u00e0y<\/p>\n<p>Gemcitabine 800-1200 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 8, 15. Chu k\u1ef3 28 ng\u00e0y<\/p>\n<ul>\n<li>Nh\u00f3m thu\u1ed1c \u1ee9c ch\u1ebf ti\u1ec3u vi qu\u1ea3n: vinorelbine, eribulin<\/li>\n<\/ul>\n<p>+ Vinorelbine 25 mg\/ m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, h\u00e0ng tu\u1ea7n.<\/p>\n<p>+ Vinorelbine 80mg\/m<sup>2<\/sup> (3 tu\u1ea7n \u0111\u1ea7u li\u1ec1u: 60mg\/m<sup>2<\/sup>), u\u1ed1ng, ng\u00e0y 1 h\u00e0ng tu\u1ea7n<\/p>\n<p>+ Vinorelbine 80mg\/m<sup>2<\/sup> (chu k\u1ef3 \u0111\u1ea7u li\u1ec1u: 60mg\/m<sup>2<\/sup>), u\u1ed1ng, ng\u00e0y 1, 8 m\u1ed7i 3 tu\u1ea7n<\/p>\n<p>+ H\u00f3a tr\u1ecb metronomic \u00e1p d\u1ee5ng cho c\u00e1c b\u1ec7nh nh\u00e2n kh\u00f4ng ph\u00f9 h\u1ee3p v\u1edbi h\u00f3a tr\u1ecb chu\u1ea9n: Vinorelbine 30mg-50mg\/ng\u00e0y, u\u1ed1ng, ng\u00e0y 1, 3, 5 h\u00e0ng tu\u1ea7n<\/p>\n<p>+ Eribulin 1,4 mg\/m<sup>2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 8. Chu k\u1ef3 21 ng\u00e0y<\/p>\n<ul>\n<li>\u1ee8c ch\u1ebf PARP (Olaparib, talazoparib): trong tr\u01a3\u1eddng h\u1ee3p HER2 (-), \u0111\u1ed9t bi\u1ebfn BRCA1\/2 d\u00f2ng m\u1ea7m (germline, di truy\u1ec1n).<\/li>\n<\/ul>\n<p>+ Olaparib 300mg u\u1ed1ng ng\u00e0y 2 l\u1ea7n (t\u1ed5ng li\u1ec1u 600mg\/ng\u00e0y) Ho\u1eb7c<\/p>\n<p>+ Talazoparib 1mg u\u1ed1ng h\u00e0ng ng\u00e0y.<\/p>\n<ul>\n<li>Platin: carboplatin, cisplatin (\u01a3u ti\u00ean cho b\u1ed9 ba \u00e2m t\u00ednh, \u0111\u1ed9t bi\u1ebfn BRCA1\/2 d\u00f2ng m\u1ea7m).<\/li>\n<\/ul>\n<p>+ Carboplatin AUC 6, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 21-28 ng\u00e0y<\/p>\n<p>+ Cisplatin 75 mg\/m2 da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 21 ng\u00e0y<\/p>\n<h4>C\u00e1c ph\u00e1c \u0111\u1ed3 kh\u00e1c<\/h4>\n<ul>\n<li>Cyclophosphamide<\/li>\n<\/ul>\n<p>+ Cyclophosphamide 50 mg, u\u1ed1ng h\u1eb1ng ng\u00e0y t\u1eeb ng\u00e0y 1-21, chu k\u1ef3 28 ng\u00e0y. &#8211; Docetaxel<\/p>\n<p>+ Docetaxel 60-100 mg\/m<sup>2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 21 ng\u00e0y. + Docetaxel 35 mg\/m<sup>2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch h\u00e0ng tu\u1ea7n trong 6 tu\u1ea7n \u0111\u1ea7u, chu k\u1ef3 8 tu\u1ea7n.<\/p>\n<ul>\n<li>Epirubicin<\/li>\n<\/ul>\n<p>+ Epirubicin 60-90 mg\/m<sup>2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 21 ng\u00e0y.<\/p>\n<ul>\n<li>Etoposide d\u1ea1ng u\u1ed1ng<\/li>\n<\/ul>\n<p>+ Etoposide 50 mg, u\u1ed1ng ng\u00e0y 1 l\u1ea7n, t\u1eeb ng\u00e0y 1-21, chu k\u1ef3 28 ng\u00e0y<\/p>\n<ul>\n<li>Mitoxantron<\/li>\n<\/ul>\n<p><strong>2.1.2 Ph\u00e1c \u0111\u1ed3 k\u1ebft h\u1ee3p<\/strong><\/p>\n<ul>\n<li>TA (paclitaxel\/doxorubicin).<\/li>\n<\/ul>\n<p>+ Doxorubicin 50 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p>+ Paclitaxel 150 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p>Chu k\u1ef3 21 ng\u00e0y. Ho\u1eb7c:<\/p>\n<p>+ Doxorubicin 60 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 21 ng\u00e0y, t\u1ed1i \u0111a 8 chu k\u1ef3<\/p>\n<p>+ Paclitaxel 175 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 21 ng\u00e0y \u0111\u1ebfn khi b\u1ec7nh ti\u1ebfn tri\u1ec3n<\/p>\n<ul>\n<li>AT (doxorubicin\/docetaxel).<\/li>\n<\/ul>\n<p>+ Doxorubicin 50 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p>+ Docetaxel 75 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p><strong>Chu k\u1ef3 21 ng\u00e0y, t\u1ed1i \u0111a 8 chu k\u1ef3<\/strong><\/p>\n<ul>\n<li>AC (doxorubicin\/cyclophosphamide)<\/li>\n<\/ul>\n<p>+ Doxorubicin 60mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p>+ Cyclophosphamide 600mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p><strong>Chu k\u1ef3 21 ng\u00e0y.<\/strong><\/p>\n<ul>\n<li>EC (epirubicin\/cyclophosphamide)<\/li>\n<\/ul>\n<p>+ Epirubicin 75mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p>+ Cyclophosphamide 600mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p><strong>Chu k\u1ef3 21 ng\u00e0y.<\/strong><\/p>\n<ul>\n<li>CAF (cyclophosphamide\/doxorubicin\/5FU)<\/li>\n<\/ul>\n<p>+ Cyclophosphamide 600mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p>+ Doxorubicin 60mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch, ng\u00e0y 1<\/p>\n<p>+ Fluorouracil 600mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p><strong>Chu k\u1ef3 21 ng\u00e0y<\/strong><\/p>\n<ul>\n<li>CEF (cyclophosphamide\/epirubicin\/5FU)<\/li>\n<\/ul>\n<p>+ Fluorouracil 500mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 8<\/p>\n<p>+ Epirubicin 60mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 8<\/p>\n<p>+ Cyclophosphamide 75mg\/m<sup>2<\/sup>, u\u1ed1ng ng\u00e0y 1-14<\/p>\n<p><strong>Chu k\u1ef3 28 ng\u00e0y<\/strong><\/p>\n<ul>\n<li>FAC (5FU\/ doxorubicin\/cyclophosphamide)<\/li>\n<\/ul>\n<p>+ Fluorouracil 500 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 4 ho\u1eb7c ng\u00e0y 1, 8<\/p>\n<p>+ Doxorubicin 50 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p>+ Cyclophosphamide 500 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p><strong>Chu k\u1ef3 21 ng\u00e0y<\/strong><\/p>\n<ul>\n<li>FEC (5FU\/epirubicin\/cyclophosphamide)<\/li>\n<\/ul>\n<p>+ Fluorouracil 600mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p>+ Epirubicin 90mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p>+ Cyclophosphamide 600mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<ul>\n<li>CMF (cyclophosphamide\/methotrexate\/fluorouracil)<\/li>\n<\/ul>\n<p><strong>\u00a0\u00a0\u00a0\u00a0 D\u01b0\u1edbi 60 tu\u1ed5i.<\/strong><\/p>\n<p>+ Cyclophosphamide 100mg\/m<sup>2<\/sup>, u\u1ed1ng, ng\u00e0y 1-14<\/p>\n<p>+ Methotrexate 40mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch, ng\u00e0y 1, 8<\/p>\n<p>+ 5-fluorouracil 600mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch, ng\u00e0y 1, 8<\/p>\n<p><strong>\u00a0\u00a0 Chu k\u1ef3 28 ng\u00e0y.<\/strong><\/p>\n<p><strong>\u00a0 \u00a0Tr\u00ean 60 tu\u1ed5i.<\/strong><\/p>\n<p>+ Cyclophosphamide 100mg\/m<sup>2<\/sup>, u\u1ed1ng, ng\u00e0y 1-14<\/p>\n<p>+ Methotrexate 30mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch, ng\u00e0y 1, 8<\/p>\n<p>+ 5-fluorouracil 400mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch, ng\u00e0y 1, 8<\/p>\n<p><strong>Chu k\u1ef3 28 ng\u00e0y.<\/strong><\/p>\n<ul>\n<li>Gemcitabine\/carboplatin<\/li>\n<\/ul>\n<p>+ Gemcitabine 1000 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 8<\/p>\n<p>+ Carboplatin AUC 2, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 8<\/p>\n<p><strong>Chu k\u1ef3 21 ng\u00e0y<\/strong><\/p>\n<ul>\n<li>Paclitaxel\/bevacizumab<\/li>\n<\/ul>\n<p>+ Paclitaxel 90 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 8, 15<\/p>\n<p>+ Bevacizumab 10 mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1,15<\/p>\n<p><strong>Chu k\u1ef3 28 ng\u00e0y<\/strong><\/p>\n<ul>\n<li>TAC (docetaxel\/doxorubicin\/cyclophosphamide)<\/li>\n<\/ul>\n<p>+ Docetaxel 75mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p>+ Doxorubicin 50mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p>+ Cyclophosphamide 500mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p><strong>Chu k\u1ef3 21 ng\u00e0y.<\/strong><\/p>\n<ul>\n<li>PE (paclitaxel\/epirubicin)<\/li>\n<\/ul>\n<p>+ Epirubicin 90 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p>+ Paclitaxel 175 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p><strong>Chu k\u1ef3 21 ng\u00e0y<\/strong><\/p>\n<ul>\n<li>Paclitaxel\/carboplatin<\/li>\n<\/ul>\n<p>+ Paclitaxel 175 mg\/ m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p>+ Carboplatin AUC 6, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1 Chu k\u1ef3 21 ng\u00e0y. Ho\u1eb7c:<\/p>\n<p>+ Paclitaxel 100 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 8, 15<\/p>\n<p>+ Carboplatin AUC 2, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 8, 15<\/p>\n<p><strong>Chu k\u1ef3 28 ng\u00e0y.<\/strong><\/p>\n<ul>\n<li>Docetaxel\/carboplatin<\/li>\n<\/ul>\n<p>+ Docetaxel 75 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p>+ Carboplatin AUC 6, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p><strong>Chu k\u1ef3 21 ng\u00e0y.<\/strong><\/p>\n<ul>\n<li>Capecitabine\/docetaxel<\/li>\n<\/ul>\n<p>+ Capecitabine 1000-1250 mg\/m<sup>2<\/sup>, u\u1ed1ng h\u1eb1ng ng\u00e0y, ng\u00e0y 2 l\u1ea7n, ng\u00e0y 1-14,<\/p>\n<p>+ Docetaxel 75 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p><strong>Chu k\u1ef3 21 ng\u00e0y<\/strong><\/p>\n<ul>\n<li>Capecitabine\/vinorelbine<\/li>\n<\/ul>\n<p>+ Vinorelbine 80mg\/m<sup>2<\/sup> (chu k\u1ef3 \u0111\u1ea7u li\u1ec1u: 60mg\/m<sup>2<\/sup>), u\u1ed1ng, ng\u00e0y 1, 8<\/p>\n<p>+ Capecitabine 2.000mg\/m<sup>2<\/sup>, u\u1ed1ng, ng\u00e0y 1-14,<\/p>\n<p><strong>Chu k\u1ef3 21 ng\u00e0y<\/strong><\/p>\n<p>H\u00f3a tr\u1ecb metronomic \u00e1p d\u1ee5ng cho c\u00e1c b\u1ec7nh nh\u00e2n kh\u00f4ng ph\u00f9 h\u1ee3p v\u1edbi h\u00f3a tr\u1ecb chu\u1ea9n:<\/p>\n<p>+ Vinorelbine 40mg\/ng\u00e0y, u\u1ed1ng, ng\u00e0y 1, 3, 5 h\u00e0ng tu\u1ea7n<\/p>\n<p>+ Capecitabine 500mg\/l\u1ea7n x 3 l\u1ea7n\/ng\u00e0y, u\u1ed1ng, li\u00ean t\u1ee5c h\u00e0ng ng\u00e0y &#8211; Gemcitabine\/paclitaxel<\/p>\n<p>+ Gemcitabine 1250 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 8 + Paclitaxel 175 mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1.<\/p>\n<p><strong>Chu k\u1ef3 21 ng\u00e0y<\/strong><\/p>\n<ul>\n<li>Atezolizumab + Nab-paclitaxel (\u00e1p d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb ung th\u01a3 v\u00fa b\u1ed9 ba \u00e2m t\u00ednh di c\u0103n ho\u1eb7c ti\u1ebfn xa t\u1ea1i ch\u1ed7 kh\u00f4ng th\u1ec3 ph\u1eabu thu\u1eadt c\u00f3 PD L-1 \u2265 1% v\u00e0 ch\u01a3a \u0111\u01a3\u1ee3c h\u00f3a tr\u1ecb tr\u01a3\u1edbc \u0111\u00f3 v\u1edbi giai \u0111o\u1ea1n di c\u0103n)<\/li>\n<\/ul>\n<p>+ Atezolizumab 840 mg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 15<\/p>\n<p>+ Nab-paclitaxel 100mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 8, 15<\/p>\n<p><strong>Chu k\u1ef3 28 ng\u00e0y<\/strong><\/p>\n<p><strong>2.1.3 M\u1ed9t s\u1ed1 ph\u00e1c \u0111\u1ed3 kh\u00e1c: <\/strong><\/p>\n<ul>\n<li>Gemcitabine\/docetaxel<\/li>\n<li>Paclitaxel\/cisplatin<\/li>\n<li>Docetaxel\/epirubicine<\/li>\n<li>Vinorelbine\/epirubicine<\/li>\n<li>Vinorelbine\/doxorubicin<\/li>\n<\/ul>\n<p><strong>2.2\u00a0 HER2 d\u01b0\u01a1ng t\u00ednh<\/strong><\/p>\n<ul>\n<li>Pertuzumab\/trastuzumab\/docetaxel<\/li>\n<\/ul>\n<p>+ Pertuzumab 840mg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 420mg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1.<\/p>\n<p>+ Trastuzumab 8mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1 theo sau 6mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1.<\/p>\n<p>+ Docetaxel 75-100mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1.<\/p>\n<p>Chu k\u1ef3 21 ng\u00e0y.<\/p>\n<ul>\n<li>Pertuzumab\/trastuzumab\/paclitaxel<\/li>\n<\/ul>\n<p>+ Pertuzumab 840mg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 420mg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 21 ng\u00e0y.<\/p>\n<p>+ Trastuzumab 8mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 6mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1 chu k\u1ef3 21 ng\u00e0y ho\u1eb7c trastuzumab 4mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 2mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1 chu k\u1ef3 m\u1ed7i tu\u1ea7n. + Paclitaxel 175mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 21 ng\u00e0y ho\u1eb7c<\/p>\n<p>+ Paclitaxel 80mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 m\u1ed7i tu\u1ea7n.<\/p>\n<ul>\n<li>Trastuzumab\/docetaxel<\/li>\n<\/ul>\n<p>+ Docetaxel 80-100mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1 chu k\u1ef3 21 ng\u00e0y ho\u1eb7c 35mg\/m2, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 8, 15, chu k\u1ef3 m\u1ed7i tu\u1ea7n.<\/p>\n<p>+ Trastuzumab 8mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 6mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch, chu k\u1ef3 21 ng\u00e0y ho\u1eb7c<\/p>\n<p>+ Trastuzumab 4mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 2mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch, chu k\u1ef3 m\u1ed7i tu\u1ea7n.<\/p>\n<ul>\n<li>Trastuzumab\/vinorelbine<\/li>\n<\/ul>\n<p>+ Vinorelbine: 25mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, m\u1ed7i tu\u1ea7n ho\u1eb7c 30-35mg\/m2, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 8, chu k\u1ef3 21 ng\u00e0y.<\/p>\n<p>+ Trastuzumab 8mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 6mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch, chu k\u1ef3 21 ng\u00e0y ho\u1eb7c<\/p>\n<p>+ Trastuzumab 4mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 2mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch, chu k\u1ef3 m\u1ed7i tu\u1ea7n.<\/p>\n<ul>\n<li>Trastuzumab\/paclitaxel<\/li>\n<\/ul>\n<p>+ Paclitaxel 175mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 21 ng\u00e0y ho\u1eb7c 8090mg\/m2, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1 chu k\u1ef3 m\u1ed7i tu\u1ea7n.<\/p>\n<p>+ Trastuzumab 8mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 6mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch, chu k\u1ef3 21 ng\u00e0y ho\u1eb7c<\/p>\n<p>+ Trastuzumab 4mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 2mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch, chu k\u1ef3 m\u1ed7i tu\u1ea7n.<\/p>\n<ul>\n<li>Trastuzumab\/paclitaxel\/carboplatin<\/li>\n<\/ul>\n<p>+ Carboplatin AUC 6, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1.<\/p>\n<p>+ Paclitaxel 175mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, chu k\u1ef3 21 ng\u00e0y.<\/p>\n<p>+ Trastuzumab 8mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 6mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch chu k\u1ef3 21 ng\u00e0y ho\u1eb7c<\/p>\n<p>+ Trastuzumab 4mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 2mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch chu k\u1ef3 m\u1ed7i tu\u1ea7n.<\/p>\n<p>Ho\u1eb7c:<\/p>\n<p>+ Carboplatin AUC 2, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 8, 15, chu k\u1ef3 28 ng\u00e0y. + Paclitaxel 80mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, 8, 15, chu k\u1ef3 28 ng\u00e0y.<\/p>\n<p>+ Trastuzumab 8mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 6mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch, chu k\u1ef3 21 ng\u00e0y ho\u1eb7c<\/p>\n<p>+ Trastuzumab 4mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 2mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch, chu k\u1ef3 m\u1ed7i tu\u1ea7n.<\/p>\n<ul>\n<li>Trastuzumab\/capecitabine<\/li>\n<\/ul>\n<p>+ Capecitabine 1.000-1.250mg\/m<sup>2<\/sup> u\u1ed1ng 2 l\u1ea7n m\u1ed7i ng\u00e0y, ng\u00e0y 1-14. Chu k\u1ef3 21 ng\u00e0y<\/p>\n<p>+ Trastuzumab 8mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 6mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch, chu k\u1ef3 21 ng\u00e0y ho\u1eb7c<\/p>\n<p>+ Trastuzumab 4mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 2mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch, chu k\u1ef3 m\u1ed7i tu\u1ea7n.<\/p>\n<ul>\n<li>Trastuzumab\/gemcitabine<\/li>\n<\/ul>\n<p>+ Gemcitabine 1200 mg\/m<sup>2<\/sup> da, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1,8<\/p>\n<p>+ Trastuzumab 4mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 2mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch, h\u00e0ng tu\u1ea7n. Chu k\u1ef3 21 ng\u00e0y<\/p>\n<ul>\n<li>TCH (docetaxel\/carboplatin\/trastuzumab). K\u00e8m theo G-CSF d\u1ef1 ph\u00f2ng nguy\u00ean ph\u00e1t.<\/li>\n<\/ul>\n<p>+ Doxetaxel 75mg\/m<sup>2<\/sup>, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p>+ Carboplatin AUC 6, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1<\/p>\n<p>Chu k\u1ef3 21 ng\u00e0y. K\u1ebft h\u1ee3p v\u1edbi Trastuzumab<\/p>\n<p>+ Trastuzumab 8mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 6mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch, chu k\u1ef3 21 ng\u00e0y\u00a0 Ho\u1eb7c<\/p>\n<p>+ Trastuzumab 4mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 2mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch, chu k\u1ef3 m\u1ed7i tu\u1ea7n.<\/p>\n<p>C\u00e1c b\u01b0\u1edbc sau:<\/p>\n<ul>\n<li>Ado-trastuzumab emtansine (T-DM1) :<\/li>\n<\/ul>\n<p>+ T-DM1 : 3,6 mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1. Chu k\u1ef3 21 ng\u00e0y &#8211; Lapatinib + capecitabine<\/p>\n<p>+ Lapatinib 1.250mg u\u1ed1ng m\u1ed7i ng\u00e0y, ng\u00e0y 1-21.<\/p>\n<p>+ Capecitabine 1.000-1.250mg\/m<sup>2<\/sup> u\u1ed1ng 2 l\u1ea7n m\u1ed7i ng\u00e0y, ng\u00e0y 1-14. Chu k\u1ef3 21 ng\u00e0y.<\/p>\n<ul>\n<li>Trastuzumab\/lapatinib (kh\u00f4ng k\u00e8m h\u00f3a ch\u1ea5t \u0111\u1ed9c t\u1ebf b\u00e0o) + Lapatinib 1.000mg u\u1ed1ng m\u1ed7i ng\u00e0y.<\/li>\n<\/ul>\n<p>+ Trastuzumab 8mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 6mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch, chu k\u1ef3 21 ng\u00e0y ho\u1eb7c<\/p>\n<p>+ Trastuzumab 4mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 1, theo sau 2mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch, chu k\u1ef3 m\u1ed7i tu\u1ea7n.<\/p>\n<ul>\n<li>Trastuzumab + c\u00e1c thu\u1ed1c kh\u00e1c<\/li>\n<\/ul>\n<p>N\u1ebfu kh\u00f4ng c\u00f3 \u0111i\u1ec1u ki\u1ec7n s\u1eed d\u1ee5ng thu\u1ed1c kh\u00e1ng HER2, \u0111i\u1ec1u tr\u1ecb theo c\u00e1c ph\u00e1c \u0111\u1ed3 nh\u01b0 v\u1edbi HER2 \u00e2m t\u00ednh.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ung th\u01b0 v\u00fa (UTV) l\u00e0 lo\u1ea1i ung th\u01b0 th\u01b0\u1eddng g\u1eb7p v\u00e0 l\u00e0 nguy\u00ean nh\u00e2n g\u00e2y t\u1eed vong h\u00e0ng \u0111\u1ea7u do ung th\u01b0 \u1edf ph\u1ee5 n\u1eef tr\u00ean to\u00e0n th\u1ebf gi\u1edbi. M\u1ed7i n\u0103m n\u01b0\u1edbc ta c\u00f3 kho\u1ea3ng h\u01a1n 15.230 ph\u1ee5 n\u1eef m\u1edbi m\u1eafc v\u00e0 h\u01a1n 6.100 ng\u01b0\u1eddi t\u1eed vong do UTV. Ung th\u01b0 v\u00fa nam chi\u1ebfm kho\u1ea3ng [&hellip;]<\/p>\n","protected":false},"author":49,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[13,33],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u0110i\u1ec1u tr\u1ecb ung th\u01b0 v\u00fa giai \u0111o\u1ea1n mu\u1ed9n, t\u00e1i ph\u00e1t, di c\u0103n - Vinmec<\/title>\n<meta name=\"description\" content=\"\u0110i\u1ec1u tr\u1ecb n\u1ed9i ti\u1ebft v\u00e0 \u0111i\u1ec1u tr\u1ecb \u0111\u00edch ung th\u01b0 v\u00fa giai \u0111o\u1ea1n mu\u1ed9n, t\u00e1i ph\u00e1t, di c\u0103n bao g\u1ed3m Th\u1ee5 th\u1ec3 n\u1ed9i ti\u1ebft d\u01b0\u01a1ng t\u00ednh, HER2 \u00e2m t\u00ednh HER2 \u00e2m t\u00ednh\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u0110i\u1ec1u tr\u1ecb ung th\u01b0 v\u00fa giai \u0111o\u1ea1n mu\u1ed9n, t\u00e1i ph\u00e1t, di c\u0103n - 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