{"id":29202,"date":"2023-05-06T15:09:07","date_gmt":"2023-05-06T08:09:07","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=29202"},"modified":"2023-05-06T15:09:07","modified_gmt":"2023-05-06T08:09:07","slug":"tuong-tac-thuoc-giua-digoxin-va-spironolactone","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/05\/06\/tuong-tac-thuoc-giua-digoxin-va-spironolactone\/","title":{"rendered":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Spironolactone"},"content":{"rendered":"<p><b>Digoxin v\u00e0 Spironolactone l\u00e0 hai lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb nhi\u1ec1u b\u1ec7nh l\u00fd kh\u00e1c nhau. Digoxin l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c ch\u1eefa c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 tim, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n nh\u1ecbp tim v\u00e0 suy tim. Trong khi \u0111\u00f3, Spironolactone l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c ch\u1eb9n receptor Aldosterone v\u00e0 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p, suy tim v\u00e0 c\u00e1c b\u1ec7nh l\u00fd li\u00ean quan \u0111\u1ebfn t\u0103ng n\u1ed3ng \u0111\u1ed9 Kali m\u00e1u. Tuy nhi\u00ean, vi\u1ec7c s\u1eed d\u1ee5ng Digoxin v\u00e0 Spironolactone c\u00f9ng nhau c\u00f3 th\u1ec3 g\u00e2y ra t\u01b0\u01a1ng t\u00e1c thu\u1ed1c v\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5 kh\u00f4ng mong mu\u1ed1n. Vi\u1ec7c t\u00ecm hi\u1ec3u v\u1ec1 t\u01b0\u01a1ng t\u00e1c thu\u1ed1c n\u00e0y l\u00e0 r\u1ea5t quan tr\u1ecdng \u0111\u1ec3 tr\u00e1nh c\u00e1c v\u1ea5n \u0111\u1ec1 s\u1ee9c kh\u1ecfe ti\u1ec1m t\u00e0ng v\u00e0 \u0111\u1ea3m b\u1ea3o hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb c\u1ee7a b\u1ec7nh nh\u00e2n.<\/b><\/p>\n<h2><b>1. Th\u00f4ng tin chung v\u1ec1 thu\u1ed1c Digoxin<\/b><\/h2>\n<h3><b>1.1 C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Digoxin l\u00e0 m\u1ed9t glycosid tr\u1ee3 tim thu t\u1eeb l\u00e1 <\/span><i><span style=\"font-weight: 400;\">Digitalis lanata<\/span><\/i><span style=\"font-weight: 400;\">. Thu\u1ed1c n\u00e0y hi\u1ec7n nay th\u01b0\u1eddng \u0111\u01b0\u1ee3c d\u00f9ng h\u01a1n Digitoxin. C\u1ea3 hai thu\u1ed1c n\u00e0y \u0111\u1ec1u c\u00f3 t\u00e1c d\u1ee5ng d\u01b0\u1ee3c l\u00fd gi\u1ed1ng nhau, nh\u01b0ng kh\u00e1c nhau v\u1ec1 \u0111\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">T\u0103ng t\u00ednh co b\u00f3p c\u01a1 tim l\u00e0 do Digoxin \u1ee9c ch\u1ebf b\u01a1m Na+\/K+ ATPase \u01a1\u0309 m\u00e0ng c\u01a1 tim l\u00e0m cho s\u1ef1 trao \u0111\u00f4\u0309i Natri trong t\u1ebf b\u00e0o v\u1edbi Kali ngo\u00e0i t\u1ebf b\u00e0o nh\u1eb1m c\u00e2n b\u1eb1ng ion b\u1ecb \u1ee9c ch\u1ebf. H\u1eadu qu\u1ea3 l\u00e0 t\u0103ng Calci n\u1ed9i b\u00e0o \u0111i v\u00e0o t\u1ebf b\u00e0o qua k\u00eanh Calci ch\u1eadm v\u00e0 gi\u1ea3m ho\u1ea1t \u0111\u1ed9ng c\u1ee7a b\u01a1m trao \u0111\u00f4\u0309i Natri \u2013 Calci ra ngo\u00e0i t\u1ebf b\u00e0o. Vi\u1ec7c gi\u1eef Calci n\u1ed9i b\u00e0o t\u0103ng l\u00ean s\u1ebd s\u1eed d\u1ee5ng nhi\u1ec1u h\u01a1n cho b\u1ed9 m\u00e1y co c\u01a1, l\u00e0m t\u0103ng co c\u01a1. Digoxin l\u00e0m gi\u1ea3m t\u00ednh d\u1eabn truy\u1ec1n c\u1ee7a tim, \u0111\u1eb7c bi\u1ec7t l\u00e0 d\u1eabn truy\u1ec1n qua n\u00fat nh\u0129 th\u1ea5t. Digoxin c\u0169ng c\u00f3 t\u00e1c d\u1ee5ng tr\u1ef1c ti\u1ebfp l\u00ean c\u01a1 tr\u01a1n m\u1ea1ch m\u00e1u v\u00e0 c\u00f3 t\u00e1c d\u1ee5ng gi\u00e1n ti\u1ebfp tr\u00ean h\u1ec7 th\u1ea7n kinh t\u1ef1 ch\u1ee7, v\u00e0 \u0111\u1eb7c bi\u1ec7t g\u00e2y t\u0103ng ho\u1ea1t t\u00ednh th\u1ea7n kinh \u0111\u1ed1i giao c\u1ea3m, gi\u1ea3m ho\u1ea1t t\u00ednh th\u1ea7n kinh giao c\u1ea3m. T\u0103ng t\u00ednh k\u00edch th\u00edch s\u1ee3i c\u01a1 tim \u01a1\u0309 li\u1ec1u cao tr\u00ean li\u1ec1u \u0111i\u1ec1u tr\u1ecb do r\u00fat ng\u1eafn th\u1eddi gian tr\u01a1, t\u0103ng t\u00ednh t\u1ef1 \u0111\u1ed9ng t\u1ebf b\u00e0o.<\/span><\/p>\n<figure id=\"attachment_23757\" aria-describedby=\"caption-attachment-23757\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-23757\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/20200612_081033_166044_digoxin-richter-50v.max-1800x1800-2-300x200.jpg\" alt=\"Digoxin\" width=\"300\" height=\"200\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/20200612_081033_166044_digoxin-richter-50v.max-1800x1800-2-300x200.jpg 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/20200612_081033_166044_digoxin-richter-50v.max-1800x1800-2.jpg 700w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-23757\" class=\"wp-caption-text\">Digoxin<\/figcaption><\/figure>\n<h3><b>1.2 Ch\u1ec9 \u0111\u1ecbnh<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Suy tim.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lo\u1ea1n nh\u1ecbp nhanh tr\u00ean th\u1ea5t (cu\u1ed3ng nh\u0129, rung nh\u0129, nh\u1ecbp nhanh tr\u00ean th\u1ea5t).<\/span><\/p>\n<h3><b>1.3 T\u00e1c d\u1ee5ng ph\u1ee5<\/b><\/h3>\n<p><b><i>Th\u01b0\u1eddng g\u1eb7p: <\/i><\/b><span style=\"font-weight: 400;\">Ch\u00e1n \u0103n, bu\u1ed3n n\u00f4n, n\u00f4n.<\/span><\/p>\n<p><b><i>\u00cdt g\u1eb7p:<\/i><\/b><span style=\"font-weight: 400;\"> Block nh\u0129 \u2013 th\u1ea5t, block xoang nh\u0129,\u00a0 lo\u1ea1n nh\u1ecbp th\u1ea5t, nh\u1ecbp \u0111\u00f4i, nh\u1ecbp ba, nh\u1ecbp nhanh nh\u0129 v\u1edbi block nh\u0129 \u2013 th\u1ea5t, ng\u1ee7 l\u01a1 m\u01a1, nh\u1ee9c \u0111\u1ea7u, m\u1ec7t m\u1ecfi, ng\u1ee7 l\u1ecbm, ch\u00f3ng m\u1eb7t, m\u1ea5t ph\u01b0\u01a1ng h\u01b0\u1edbng, t\u0103ng Kali huy\u1ebft v\u1edbi ng\u1ed9 \u0111\u1ed9c c\u1ea5p, kh\u00f4ng dung n\u1ea1p th\u1ee9c \u0103n, \u0111au b\u1ee5ng, ti\u00eau ch\u1ea3y, \u0111au d\u00e2y th\u1ea7n kinh, nh\u00ecn m\u1edd, nh\u00ecn v\u00e0ng ho\u1eb7c xanh l\u00e1 c\u00e2y,&#8230;<\/span><\/p>\n<h2><b>2. Th\u00f4ng tin chung v\u1ec1 thu\u1ed1c Spironolactone<\/b><\/h2>\n<h3><b>2.1 C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Spironolactone l\u00e0 m\u1ed9t steroid c\u00f3 c\u1ea5u tr\u00fac gi\u1ed1ng Aldosteron (hormon tuy\u1ebfn th\u01b0\u1ee3ng th\u1eadn). Thu\u1ed1c l\u00e0 ch\u1ea5t \u0111\u1ed1i kh\u00e1ng th\u1ee5 th\u1ec3 mineralocorticoid kh\u00f4ng ch\u1ecdn l\u1ecdc (Aldosteron) v\u00e0 c\u0169ng l\u00e0 m\u1ed9t ch\u1ea5t \u0111\u1ed1i kh\u00e1ng th\u1ee5 th\u1ec3 Androgen v\u00e0 Progesteron. Spironolactone c\u00f3 t\u00e1c d\u1ee5ng gi\u1eef Magnesi v\u00e0 Kali, Natri-ni\u1ec7u, l\u1ee3i ti\u1ec3u v\u00e0 l\u00e0m h\u1ea1 huy\u1ebft \u00e1p do \u1ee9c ch\u1ebf c\u1ea1nh tranh t\u00e1c d\u1ee5ng sinh l\u00fd c\u1ee7a Aldosteron tr\u00ean \u1ed1ng l\u01b0\u1ee3n xa, c\u01a1 tim v\u00e0 h\u1ec7 m\u1ea1ch.<\/span><\/p>\n<figure id=\"attachment_31831\" aria-describedby=\"caption-attachment-31831\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-31831\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/Spironolactone-300x200.jpg\" alt=\"Spironolactone\" width=\"300\" height=\"200\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/Spironolactone-300x200.jpg 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/05\/Spironolactone.jpg 630w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-31831\" class=\"wp-caption-text\">Spironolactone<\/figcaption><\/figure>\n<h3><b>2.2 Ch\u1ec9 \u0111\u1ecbnh<\/b><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ph\u00f9 do t\u0103ng qu\u00e1 m\u1ee9c Aldosteron (nh\u01b0 ph\u00f9 v\u00f4 c\u0103n, ph\u00f9 do x\u01a1 gan, h\u1ed9i ch\u1ee9ng th\u1eadn h\u01b0, suy tim sung huy\u1ebft). Th\u01b0\u1eddng ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c l\u1ee3i ti\u1ec3u kh\u00e1c.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">T\u0103ng huy\u1ebft \u00e1p: Th\u01b0\u1eddng ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c l\u1ee3i ti\u1ec3u kh\u00e1c ho\u1eb7c thu\u1ed1c ch\u1ed1ng t\u0103ng huy\u1ebft \u00e1p. T\u00e1c d\u1ee5ng k\u00e9m n\u1ebfu d\u00f9ng \u0111\u01a1n \u0111\u1ed9c.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><a href=\"https:\/\/www.vinmec.com\/en\/tim-mach\/thong-tin-suc-khoe\/tim-hieu-ve-benh-suy-tim-sung-huyet\/\">Suy tim sung huy\u1ebft<\/a>: D\u00f9ng li\u1ec1u th\u1ea5p, ph\u1ed1i h\u1ee3p v\u1edbi m\u1ed9t thu\u1ed1c \u1ee9c ch\u1ebf enzym chuy\u1ec3n \u0111\u1ed5i angiotensin.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">T\u0103ng Aldosteron ti\u00ean ph\u00e1t: \u0110i\u1ec1u tr\u1ecb ng\u1eafn tr\u01b0\u1edbc ph\u1eabu thu\u1eadt t\u0103ng aldosteron ti\u00ean ph\u00e1t ho\u1eb7c \u0111i\u1ec1u tr\u1ecb duy tr\u00ec l\u00e2u d\u00e0i ng\u01b0\u1eddi b\u1ecb adenoma tuy\u1ebfn th\u01b0\u1ee3ng th\u1eadn ti\u1ebft aldosteron \u00edt nh\u01b0ng kh\u00f4ng ph\u1eabu thu\u1eadt ho\u1eb7c t\u0103ng Aldosteron v\u00f4 c\u0103n (t\u0103ng s\u1ea3n tuy\u1ebfn th\u01b0\u1ee3ng th\u1eadn).<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">D\u1eady th\u00ec s\u1edbm: Ph\u1ed1i h\u1ee3p v\u1edbi Testolacton trong \u0111i\u1ec1u tr\u1ecb m\u1ed9t s\u1ed1 th\u1ec3 d\u1eady th\u00ec s\u1edbm kh\u00f4ng ph\u1ee5 thu\u1ed9c GnRH (d\u1eady th\u00ec s\u1edbm c\u00f3 t\u00ednh di truy\u1ec1n \u1edf nam).<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ch\u1ec9 \u0111\u1ecbnh kh\u00e1c: Ch\u1ee9ng r\u1eadm l\u00f4ng \u1edf ph\u1ee5 n\u1eef b\u1ecb h\u1ed9i ch\u1ee9ng \u0111a u nang ho\u1eb7c r\u1eadm l\u00f4ng v\u00f4 c\u0103n.<\/span><\/li>\n<\/ul>\n<h3><b>2.3 T\u00e1c d\u1ee5ng ph\u1ee5<\/b><\/h3>\n<p><b><i>Th\u01b0\u1eddng g\u1eb7p:<\/i><\/b><span style=\"font-weight: 400;\"> M\u1ec7t m\u1ecfi, nh\u1ee9c \u0111\u1ea7u, ng\u1ee7 g\u00e0, l\u00fa l\u1eabn. T\u0103ng Prolactin, to v\u00fa \u0111\u00e0n \u00f4ng, ch\u1ea3y s\u1eefa nhi\u1ec1u, r\u1ed1i lo\u1ea1n kinh nguy\u1ec7t, m\u1ea5t kinh, ch\u1ea3y m\u00e1u sau m\u00e3n kinh, li\u1ec7t d\u01b0\u01a1ng, r\u1eadm l\u00f4ng. Ti\u00eau ch\u1ea3y, bu\u1ed3n n\u00f4n, ch\u00e1n \u0103n, \u0111au qu\u1eb7n b\u1ee5ng.<\/span><\/p>\n<p><b><i>\u00cdt g\u1eb7p:<\/i><\/b><span style=\"font-weight: 400;\"> Ban \u0111\u1ecf, ngo\u1ea1i ban, m\u00e0y \u0111ay, h\u1ed9i ch\u1ee9ng Stevens-Johnson. T\u0103ng Kali huy\u1ebft, gi\u1ea3m Natri huy\u1ebft, t\u0103ng acid uric huy\u1ebft. Chu\u1ed9t r\u00fat\/co th\u1eaft c\u01a1, d\u1ecb c\u1ea3m, m\u1ea5t \u0111i\u1ec1u h\u00f2a v\u1eadn \u0111\u1ed9ng. T\u0103ng Creatinin huy\u1ebft thanh, suy th\u1eadn c\u1ea5p, t\u0103ng Nit\u01a1 Ur\u00ea huy\u1ebft (BUN), \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n c\u00f3 suy th\u1eadn t\u1eeb tr\u01b0\u1edbc.<\/span><\/p>\n<p><b><i>Hi\u1ebfm g\u1eb7p:<\/i><\/b><span style=\"font-weight: 400;\"> M\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t, gi\u1ea3m ti\u1ec3u c\u1ea7u.<\/span><\/p>\n<h2><b>3. T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Spironolactone<\/b><\/h2>\n<h3><b>3.1 C\u01a1 ch\u1ebf<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Spironolactone v\u00e0 Digoxin \u0111\u1ec1u l\u00e0m gi\u1ea3m thanh th\u1ea3i th\u1eadn.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Spironolactone l\u00e0m t\u0103ng m\u1ee9c \u0111\u1ed9 Digoxin v\u1edbi c\u01a1 ch\u1ebf ch\u01b0a r\u00f5 r\u00e0ng\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Spironolactone v\u00e0 Digoxin \u0111\u1ec1u l\u00e0m t\u0103ng Kali huy\u1ebft thanh.\u00a0<\/span><\/p>\n<h3><b>3.2 T\u00e1c d\u1ee5ng ph\u1ee5 c\u00f3 th\u1ec3 x\u1ea3y ra khi s\u1eed d\u1ee5ng Digoxin v\u00e0 Spironolactone c\u00f9ng nhau<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Vi\u1ec7c s\u1eed d\u1ee5ng Digoxin v\u00e0 Spironolactone c\u00f9ng nhau c\u00f3 th\u1ec3 g\u00e2y ra m\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 kh\u00e1c nhau, bao g\u1ed3m:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">T\u0103ng Kali m\u00e1u: d\u1eabn \u0111\u1ebfn c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 bu\u1ed3n n\u00f4n, \u0111au \u0111\u1ea7u, m\u1ec7t m\u1ecfi v\u00e0 r\u1ed1i lo\u1ea1n nh\u1ecbp tim.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">C\u1ea3 Digoxin v\u00e0 Spironolactone \u0111\u1ec1u \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a v\u00e0 b\u00e0i ti\u1ebft qua th\u1eadn. Khi s\u1eed d\u1ee5ng chung, ch\u00fang c\u00f3 th\u1ec3 g\u00e2y ra t\u00e1c d\u1ee5ng ph\u1ee5 cho c\u00e1c b\u1ec7nh nh\u00e2n v\u1edbi ch\u1ee9c n\u0103ng th\u1eadn k\u00e9m ho\u1eb7c suy th\u1eadn.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">T\u00e1c d\u1ee5ng kh\u00e1c: Ngo\u00e0i nh\u1eefng t\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean, s\u1eed d\u1ee5ng chung Digoxin v\u00e0 Spironolactone c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 kh\u00e1c nh\u01b0 \u0111au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t, bu\u1ed3n n\u00f4n, ti\u00eau ch\u1ea3y v\u00e0 t\u0103ng huy\u1ebft \u00e1p.<\/span><\/li>\n<\/ul>\n<h3><b>3.3 Bi\u1ec7n ph\u00e1p x\u1eed l\u00fd t\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Spironolactone<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Vi\u1ec7c x\u1eed l\u00fd t\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Spironolactone c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1eb1ng c\u00e1ch th\u1ef1c hi\u1ec7n c\u00e1c bi\u1ec7n ph\u00e1p sau:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u0110i\u1ec1u ch\u1ec9nh li\u1ec1u l\u01b0\u1ee3ng: C\u00f3 th\u1ec3 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u l\u01b0\u1ee3ng c\u1ee7a Digoxin v\u00e0 Spironolactone \u0111\u1ec3 tr\u00e1nh t\u00ecnh tr\u1ea1ng t\u0103ng kali m\u00e1u.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gi\u00e1m s\u00e1t ch\u1ee9c n\u0103ng th\u1eadn: C\u1ea7n \u0111\u01b0\u1ee3c gi\u00e1m s\u00e1t ch\u1ee9c n\u0103ng th\u1eadn th\u01b0\u1eddng xuy\u00ean. N\u1ebfu b\u1ec7nh nh\u00e2n c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn k\u00e9m ho\u1eb7c suy th\u1eadn, b\u00e1c s\u0129 c\u00f3 th\u1ec3 gi\u1ea3m li\u1ec1u l\u01b0\u1ee3ng thu\u1ed1c ho\u1eb7c \u0111i\u1ec1u ch\u1ec9nh th\u1eddi gian s\u1eed d\u1ee5ng.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ki\u1ec3m tra \u0111i\u1ec7n gi\u1ea3i v\u00e0 nh\u1ecbp tim: B\u00e1c s\u0129 c\u00f3 th\u1ec3 ki\u1ec3m tra \u0111i\u1ec7n gi\u1ea3i v\u00e0 nh\u1ecbp tim c\u1ee7a b\u1ec7nh nh\u00e2n th\u01b0\u1eddng xuy\u00ean \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 t\u00ecnh tr\u1ea1ng r\u1ed1i lo\u1ea1n \u0111i\u1ec7n gi\u1ea3i v\u00e0 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u l\u01b0\u1ee3ng thu\u1ed1c.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Thay \u0111\u1ed5i thu\u1ed1c: N\u1ebfu t\u01b0\u01a1ng t\u00e1c thu\u1ed1c g\u00e2y ra t\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng ho\u1eb7c kh\u00f4ng th\u1ec3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c, b\u00e1c s\u0129 c\u00f3 th\u1ec3 thay \u0111\u1ed5i thu\u1ed1c ho\u1eb7c ch\u1ecdn c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb kh\u00e1c.<\/span><\/li>\n<\/ul>\n<h3><b>3.4 M\u1ee9c \u0111\u1ed9 t\u01b0\u01a1ng t\u00e1c thu\u1ed1c t\u1eeb nhi\u1ec1u ngu\u1ed3n kh\u00e1c nhau<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Drug: Nh\u1eb9<\/span><\/p>\n<p><span style=\"font-weight: 400;\">WebMD: V\u1eeba ph\u1ea3i<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Medscape: V\u1eeba ph\u1ea3i<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ngu\u1ed3n: D\u01b0\u1ee3c th\u01b0 Qu\u1ed1c gia Vi\u1ec7t Nam<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Digoxin v\u00e0 Spironolactone l\u00e0 hai lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb nhi\u1ec1u b\u1ec7nh l\u00fd kh\u00e1c nhau. Digoxin l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c ch\u1eefa c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 tim, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n nh\u1ecbp tim v\u00e0 suy tim. Trong khi \u0111\u00f3, Spironolactone l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c ch\u1eb9n receptor Aldosterone v\u00e0 \u0111\u01b0\u1ee3c [&hellip;]<\/p>\n","protected":false},"author":53,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[12],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Spironolactone - Vinmec<\/title>\n<meta name=\"description\" content=\"Digoxin v\u00e0 Spironolactone l\u00e0 hai lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb nhi\u1ec1u b\u1ec7nh l\u00fd kh\u00e1c nhau. 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