{"id":29002,"date":"2023-04-28T19:52:51","date_gmt":"2023-04-28T12:52:51","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=29002"},"modified":"2023-04-28T19:52:51","modified_gmt":"2023-04-28T12:52:51","slug":"vai-tro-sinh-thiet-than-kinh-co-trong-benh-than-kinh-ngoai-bien","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/28\/vai-tro-sinh-thiet-than-kinh-co-trong-benh-than-kinh-ngoai-bien\/","title":{"rendered":"Vai tr\u00f2 sinh thi\u1ebft th\u1ea7n kinh c\u01a1 trong b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean"},"content":{"rendered":"

Sinh thi\u1ebft th\u1ea7n kinh-c\u01a1 ch\u1ec9 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh ch\u1ecdn l\u1ecdc trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p \u0111\u1eb7c bi\u1ec7t nh\u01b0 b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean c\u1ee7a b\u1ec7nh vi\u00eam m\u1ea1ch<\/a>, b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean c\u1ee7a b\u1ec7nh collagen, b\u1ec7nh phong, b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean ph\u00ec \u0111\u1ea1i v\u00e0 c\u00e1c b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean c\u1ee7a b\u1ec7nh t\u1ed3n \u0111\u1ecdng do r\u1ed1i lo\u1ea1n chuy\u1ec3n ho\u00e1. Sinh thi\u1ebft th\u1ea7n kinh-c\u01a1 c\u00f3 vai tr\u00f2 quan tr\u1ecdng trong ch\u1ea9n \u0111o\u00e1n c\u00e1c b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean.<\/strong><\/p>\n

\"\"
Sinh thi\u1ebft th\u1ea7n kinh-c\u01a1 ch\u1ec9 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh ch\u1ecdn l\u1ecdc trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p \u0111\u1eb7c bi\u1ec7t nh\u01b0 b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean<\/figcaption><\/figure>\n

1. Sinh thi\u1ebft th\u1ea7n kinh- c\u01a1 l\u00e0 g\u00ec?<\/h2>\n

Sinh thi\u1ebft th\u1ea7n kinh- c\u01a1 (nerve-muscle biopsy<\/a>) l\u00e0 m\u1ed9t th\u1ee7 thu\u1eadt y t\u1ebf \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 l\u1ea5y m\u1eabu t\u1ebf b\u00e0o t\u1eeb th\u1ea7n kinh v\u00e0 c\u01a1 \u0111\u1ec3 ph\u00e2n t\u00edch v\u00e0 ch\u1ea9n \u0111o\u00e1n c\u00e1c b\u1ec7nh li\u00ean quan \u0111\u1ebfn h\u1ec7 th\u1ea7n kinh v\u00e0 c\u01a1 b\u1eafp.<\/p>\n

Th\u1ee7 thu\u1eadt n\u00e0y th\u01b0\u1eddng \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1eb1ng c\u00e1ch l\u1ea5y m\u1ed9t m\u1eabu t\u1ebf b\u00e0o nh\u1ecf t\u1eeb c\u01a1 b\u1eafp ho\u1eb7c th\u1ea7n kinh c\u1ee7a b\u1ec7nh nh\u00e2n th\u00f4ng qua m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p ph\u1eabu thu\u1eadt. M\u1eabu t\u1ebf b\u00e0o sau \u0111\u00f3 \u0111\u01b0\u1ee3c chuy\u1ec3n \u0111\u1ebfn ph\u00f2ng th\u00ed nghi\u1ec7m \u0111\u1ec3 ph\u00e2n t\u00edch v\u00e0 \u0111\u00e1nh gi\u00e1.<\/p>\n

Sinh thi\u1ebft th\u1ea7n kinh- c\u01a1 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n nhi\u1ec1u b\u1ec7nh li\u00ean quan \u0111\u1ebfn h\u1ec7 th\u1ea7n kinh v\u00e0 c\u01a1, bao g\u1ed3m b\u1ec7nh th\u1ea7n kinh v\u1eadn \u0111\u1ed9ng, b\u1ec7nh th\u1ea7n kinh c\u1ea3m gi\u00e1c, b\u1ec7nh v\u1ec1 c\u01a1 v\u00e0 c\u00e1c b\u1ec7nh kh\u00e1c li\u00ean quan \u0111\u1ebfn ch\u1ee9c n\u0103ng th\u1ea7n kinh v\u00e0 c\u01a1.<\/p>\n

Tuy nhi\u00ean, th\u1ee7 thu\u1eadt n\u00e0y c\u0169ng c\u00f3 m\u1ed9t s\u1ed1 r\u1ee7i ro nh\u01b0 nhi\u1ec5m tr\u00f9ng, \u0111au v\u00e0 ch\u1ea3y m\u00e1u. Do \u0111\u00f3, n\u00f3 th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng ch\u1ec9 khi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p ch\u1ea9n \u0111o\u00e1n kh\u00e1c kh\u00f4ng cung c\u1ea5p \u0111\u1ee7 th\u00f4ng tin ho\u1eb7c kh\u00f4ng ch\u00ednh x\u00e1c.<\/p>\n

2. Vai tr\u00f2 c\u1ee7a sinh thi\u1ebft th\u1ea7n kinh – c\u01a1<\/h2>\n

2.1. C\u00f3 gi\u00e1 tr\u1ecb ch\u1ea9n \u0111o\u00e1n<\/h3>\n
    \n
  • Vi\u00eam m\u1ea1ch ho\u1ea1i t\u1eed<\/li>\n
  • B\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean trong ch\u1ee9ng tho\u00e1i h\u00f3a d\u1ea1ng tinh b\u1ed9t (amyloid)<\/li>\n
  • B\u1ec7nh phong<\/li>\n
  • B\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean sarcoid<\/li>\n
  • U bao Schwann<\/li>\n
  • Th\u00e2m nhi\u1ec5m do t\u1ebf b\u00e0o \u00e1c tinh<\/li>\n
  • B\u1ec7nh D\u00e9jerine – Sottas<\/li>\n
  • L\u1ecdan d\u01b0\u1ee1ng ch\u1ea5t tr\u1eafng d\u1ecb s\u1eafc<\/li>\n<\/ul>\n

    2.2. C\u00f3 th\u1ec3 h\u1ed7 tr\u1ee3 cho ch\u1ea9n \u0111o\u00e1n<\/h3>\n
      \n
    • B\u1ec7nh vi\u00eam th\u1ea7n kinh ngo\u1ea1i bi\u00ean m\u1ea5t myelin<\/li>\n
    • B\u1ec7nh Charcot – Marie – Tooth<\/li>\n
    • C\u00e1c b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean di truy\u1ec1n kh\u00e1c<\/li>\n
    • B\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean c\u1eadn ung th\u01b0<\/li>\n
    • B\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean trong b\u1ec7nh protein \u0111\u01a1n d\u00f2ng<\/li>\n
    • C\u00e1c b\u1ec7nh vi\u00eam th\u1ea7n kinh ngo\u1ea1i bi\u00ean kh\u00e1c<\/li>\n<\/ul>\n

      3. \u01afu \u0111i\u1ec3m c\u1ee7a sinh thi\u1ebft th\u1ea7n kinh- c\u01a1<\/h2>\n

      Sinh thi\u1ebft th\u1ea7n kinh- c\u01a1 (nerve-muscle biopsy) l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p ch\u1ea9n \u0111o\u00e1n quan tr\u1ecdng trong b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean (Peripheral Nervous System – PNS), v\u00e0 c\u00f3 nhi\u1ec1u \u01b0u \u0111i\u1ec3m nh\u01b0 sau:<\/p>\n

      – Cung c\u1ea5p th\u00f4ng tin ch\u00ednh x\u00e1c v\u1ec1 b\u1ec7nh: Sinh thi\u1ebft th\u1ea7n kinh- c\u01a1 gi\u00fap cung c\u1ea5p th\u00f4ng tin ch\u00ednh x\u00e1c v\u1ec1 t\u00ecnh tr\u1ea1ng b\u1ec7nh c\u1ee7a b\u1ec7nh nh\u00e2n, bao g\u1ed3m c\u00e1c d\u1ea5u hi\u1ec7u v\u00e0 tri\u1ec7u ch\u1ee9ng c\u1ee7a b\u1ec7nh, v\u00e0 gi\u00fap x\u00e1c \u0111\u1ecbnh ch\u00ednh x\u00e1c lo\u1ea1i b\u1ec7nh. \u0110i\u1ec1u n\u00e0y gi\u00fap cho c\u00e1c chuy\u00ean gia y t\u1ebf c\u00f3 th\u1ec3 \u0111\u01b0a ra quy\u1ebft \u0111\u1ecbnh ch\u00ednh x\u00e1c h\u01a1n v\u1ec1 \u0111i\u1ec1u tr\u1ecb v\u00e0 ch\u0103m s\u00f3c cho b\u1ec7nh nh\u00e2n.<\/p>\n

      – Ph\u00e1t hi\u1ec7n s\u1edbm b\u1ec7nh: Sinh thi\u1ebft th\u1ea7n kinh- c\u01a1 c\u00f3 th\u1ec3 ph\u00e1t hi\u1ec7n s\u1edbm c\u00e1c b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean, gi\u00fap cho b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb k\u1ecbp th\u1eddi.<\/p>\n

      – X\u00e1c \u0111\u1ecbnh m\u1ee9c \u0111\u1ed9 t\u1ed5n th\u01b0\u01a1ng c\u1ee7a th\u1ea7n kinh: Sinh thi\u1ebft th\u1ea7n kinh- c\u01a1 cung c\u1ea5p th\u00f4ng tin v\u1ec1 m\u1ee9c \u0111\u1ed9 t\u1ed5n th\u01b0\u01a1ng c\u1ee7a th\u1ea7n kinh, gi\u00fap cho c\u00e1c chuy\u00ean gia y t\u1ebf \u0111\u01b0a ra quy\u1ebft \u0111\u1ecbnh ch\u00ednh x\u00e1c h\u01a1n v\u1ec1 \u0111i\u1ec1u tr\u1ecb v\u00e0 ch\u0103m s\u00f3c cho b\u1ec7nh nh\u00e2n.<\/p>\n

      – \u0110\u00e1nh gi\u00e1 hi\u1ec7u qu\u1ea3 c\u1ee7a \u0111i\u1ec1u tr\u1ecb: Sau khi \u0111i\u1ec1u tr\u1ecb, sinh thi\u1ebft th\u1ea7n kinh- c\u01a1 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 hi\u1ec7u qu\u1ea3 c\u1ee7a \u0111i\u1ec1u tr\u1ecb, gi\u00fap cho c\u00e1c chuy\u00ean gia y t\u1ebf \u0111\u01b0a ra quy\u1ebft \u0111\u1ecbnh ch\u00ednh x\u00e1c h\u01a1n v\u1ec1 \u0111i\u1ec1u tr\u1ecb ti\u1ebfp theo.<\/p>\n

      4. H\u1ea1n ch\u1ebf<\/h2>\n

      Sinh thi\u1ebft th\u1ea7n kinh- c\u01a1 l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p ch\u1ea9n \u0111o\u00e1n quan tr\u1ecdng trong b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean. Tuy nhi\u00ean, n\u00f3 c\u0169ng c\u00f3 m\u1ed9t s\u1ed1 h\u1ea1n ch\u1ebf nh\u01b0 sau:<\/p>\n

      – R\u1ee7i ro nhi\u1ec5m tr\u00f9ng: Sinh thi\u1ebft th\u1ea7n kinh- c\u01a1 l\u00e0 m\u1ed9t th\u1ee7 thu\u1eadt y t\u1ebf ph\u1ee9c t\u1ea1p v\u00e0 c\u00f3 r\u1ee7i ro nhi\u1ec5m tr\u00f9ng. \u0110i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c v\u1ea5n \u0111\u1ec1 s\u1ee9c kh\u1ecfe nghi\u00eam tr\u1ecdng cho b\u1ec7nh nh\u00e2n.<\/p>\n

      – \u0110au v\u00e0 ch\u1ea3y m\u00e1u: Sinh thi\u1ebft th\u1ea7n kinh- c\u01a1 c\u0169ng c\u00f3 th\u1ec3 g\u00e2y ra \u0111au v\u00e0 ch\u1ea3y m\u00e1u \u1edf v\u00f9ng l\u1ea5y m\u1eabu, g\u00e2y kh\u00f3 ch\u1ecbu v\u00e0 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ch\u1ea5t l\u01b0\u1ee3ng cu\u1ed9c s\u1ed1ng c\u1ee7a b\u1ec7nh nh\u00e2n.<\/p>\n

      – Chi ph\u00ed cao: Sinh thi\u1ebft th\u1ea7n kinh- c\u01a1 l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p ch\u1ea9n \u0111o\u00e1n ph\u1ee9c t\u1ea1p, y\u00eau c\u1ea7u k\u1ef9 thu\u1eadt cao v\u00e0 ti\u00eau t\u1ed1n nhi\u1ec1u ngu\u1ed3n l\u1ef1c v\u00e0 chi ph\u00ed, g\u00e2y kh\u00f3 kh\u0103n cho b\u1ec7nh nh\u00e2n trong vi\u1ec7c truy c\u1eadp v\u00e0 s\u1eed d\u1ee5ng d\u1ecbch v\u1ee5 y t\u1ebf.<\/p>\n

      – Kh\u00f3 kh\u0103n trong vi\u1ec7c l\u1ea5y m\u1eabu: L\u1ea5y m\u1eabu t\u1ebf b\u00e0o t\u1eeb th\u1ea7n kinh v\u00e0 c\u01a1 b\u1eafp y\u00eau c\u1ea7u k\u1ef9 thu\u1eadt cao v\u00e0 c\u1ea7n \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1edfi nh\u1eefng chuy\u00ean gia c\u00f3 kinh nghi\u1ec7m. Vi\u1ec7c l\u1ea5y m\u1eabu kh\u00f4ng \u0111\u00fang c\u00e1ch c\u00f3 th\u1ec3 g\u00e2y ra nhi\u1ec1u v\u1ea5n \u0111\u1ec1 cho b\u1ec7nh nh\u00e2n.<\/p>\n

      Do \u0111\u00f3, sinh thi\u1ebft th\u1ea7n kinh- c\u01a1 th\u01b0\u1eddng ch\u1ec9 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng khi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p ch\u1ea9n \u0111o\u00e1n kh\u00e1c kh\u00f4ng cung c\u1ea5p \u0111\u1ee7 th\u00f4ng tin ho\u1eb7c kh\u00f4ng ch\u00ednh x\u00e1c. B\u1ec7nh nh\u00e2n n\u00ean th\u1ea3o lu\u1eadn v\u1edbi b\u00e1c s\u0129 \u0111\u1ec3 hi\u1ec3u r\u00f5 v\u1ec1 c\u00e1c r\u1ee7i ro v\u00e0 l\u1ee3i \u00edch c\u1ee7a th\u1ee7 thu\u1eadt n\u00e0y tr\u01b0\u1edbc khi quy\u1ebft \u0111\u1ecbnh s\u1eed d\u1ee5ng.<\/p>\n

      T\u00f3m l\u1ea1i, sinh thi\u1ebft th\u1ea7n kinh- c\u01a1 l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p ch\u1ea9n \u0111o\u00e1n quan tr\u1ecdng trong b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean (Peripheral Nervous System – PNS), gi\u00fap cung c\u1ea5p th\u00f4ng tin ch\u00ednh x\u00e1c v\u1ec1 t\u00ecnh tr\u1ea1ng b\u1ec7nh c\u1ee7a b\u1ec7nh nh\u00e2n, ph\u00e1t hi\u1ec7n s\u1edbm b\u1ec7nh, x\u00e1c \u0111\u1ecbnh m\u1ee9c \u0111\u1ed9 t\u1ed5n th\u01b0\u01a1ng c\u1ee7a th\u1ea7n kinh, v\u00e0 \u0111\u00e1nh gi\u00e1 hi\u1ec7u qu\u1ea3 c\u1ee7a \u0111i\u1ec1u tr\u1ecb. Tuy nhi\u00ean, sinh thi\u1ebft th\u1ea7n kinh- c\u01a1 c\u0169ng c\u00f3 m\u1ed9t s\u1ed1 h\u1ea1n ch\u1ebf nh\u01b0 r\u1ee7i ro nhi\u1ec5m tr\u00f9ng, \u0111au v\u00e0 ch\u1ea3y m\u00e1u, chi ph\u00ed cao, v\u00e0 kh\u00f3 kh\u0103n trong vi\u1ec7c l\u1ea5y m\u1eabu. Do \u0111\u00f3, n\u00f3 ch\u1ec9 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng khi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p ch\u1ea9n \u0111o\u00e1n kh\u00e1c kh\u00f4ng cung c\u1ea5p \u0111\u1ee7 th\u00f4ng tin ho\u1eb7c kh\u00f4ng ch\u00ednh x\u00e1c. B\u1ec7nh nh\u00e2n n\u00ean th\u1ea3o lu\u1eadn v\u1edbi b\u00e1c s\u0129 \u0111\u1ec3 hi\u1ec3u r\u00f5 v\u1ec1 c\u00e1c r\u1ee7i ro v\u00e0 l\u1ee3i \u00edch c\u1ee7a th\u1ee7 thu\u1eadt n\u00e0y tr\u01b0\u1edbc khi quy\u1ebft \u0111\u1ecbnh s\u1eed d\u1ee5ng.<\/p>\n","protected":false},"excerpt":{"rendered":"

      Sinh thi\u1ebft th\u1ea7n kinh-c\u01a1 ch\u1ec9 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh ch\u1ecdn l\u1ecdc trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p \u0111\u1eb7c bi\u1ec7t nh\u01b0 b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean c\u1ee7a b\u1ec7nh vi\u00eam m\u1ea1ch, b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean c\u1ee7a b\u1ec7nh collagen, b\u1ec7nh phong, b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean ph\u00ec \u0111\u1ea1i v\u00e0 c\u00e1c b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean c\u1ee7a b\u1ec7nh t\u1ed3n \u0111\u1ecdng […]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[10,33],"tags":[],"yoast_head":"\nVai tr\u00f2 sinh thi\u1ebft th\u1ea7n kinh c\u01a1 trong b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean<\/title>\n<meta name=\"description\" content=\"Sinh thi\u1ebft th\u1ea7n kinh-c\u01a1 ch\u1ec9 \u0111\u01b0\u1ee3c ch\u1ec9 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