{"id":28528,"date":"2023-06-22T15:05:53","date_gmt":"2023-06-22T08:05:53","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=28528"},"modified":"2023-06-22T15:05:53","modified_gmt":"2023-06-22T08:05:53","slug":"xarelto-va-eliquis-nhung-diem-tuong-dong-va-khac-biet","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/06\/22\/xarelto-va-eliquis-nhung-diem-tuong-dong-va-khac-biet\/","title":{"rendered":"Xarelto v\u00e0 Eliquis: Nh\u1eefng \u0111i\u1ec3m t\u01b0\u01a1ng \u0111\u1ed3ng v\u00e0 kh\u00e1c bi\u1ec7t"},"content":{"rendered":"

Xarelto v\u00e0 Eliquis l\u00e0 hai lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng ph\u1ed5 bi\u1ebfn trong \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh li\u00ean quan \u0111\u1ebfn \u0111\u00f4ng m\u00e1u. C\u1ea3 hai \u0111\u1ec1u thu\u1ed9c nh\u00f3m thu\u1ed1c kh\u00e1ng vitamin K, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 ng\u0103n ng\u1eeba c\u00e1c c\u1ee5c m\u00e1u \u0111\u00f4ng trong c\u01a1 th\u1ec3. Tuy nhi\u00ean, ch\u00fang c\u0169ng c\u00f3 nh\u1eefng \u0111i\u1ec3m kh\u00e1c bi\u1ec7t quan tr\u1ecdng v\u1ec1 c\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng, li\u1ec1u l\u01b0\u1ee3ng v\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5. Trong b\u00e0i vi\u1ebft n\u00e0y, ch\u00fang ta s\u1ebd t\u00ecm hi\u1ec3u s\u00e2u h\u01a1n v\u1ec1 nh\u1eefng \u0111i\u1ec3m t\u01b0\u01a1ng \u0111\u1ed3ng v\u00e0 kh\u00e1c bi\u1ec7t gi\u1eefa Xarelto v\u00e0 Eliquis.<\/strong><\/p>\n

1.Gi\u1edbi thi\u1ec7u chung\u00a0<\/strong><\/h2>\n

1.1 T\u00ecm hi\u1ec3u chung v\u1ec1 thu\u1ed1c Xarelto (Rivaroxaban)<\/span><\/h3>\n

Xarelto<\/a> (Rivaroxaban) l\u00e0 thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u m\u1edbi (NOAC) thu\u1ed9c nh\u00f3m thu\u1ed1c \u1ee9c ch\u1ebf y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u Xa d\u1ea1ng u\u1ed1ng \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb v\u00e0 ki\u1ec3m so\u00e1t thuy\u00ean t\u1eafc huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch nh\u01b0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p d\u1ef1 ph\u00f2ng huy\u1ebft kh\u1ed1i sau ph\u1eabu thu\u1eadt cho b\u1ec7nh nh\u00e2n tr\u1ea3i qua ph\u1eabu thu\u1eadt ch\u1ec9nh h\u00ecnh \u0111\u1ec3 ng\u0103n ng\u1eeba \u0111\u1ed9t qu\u1ef5 \u1edf b\u1ec7nh nh\u00e2n rung t\u00e2m nh\u0129 kh\u00f4ng do b\u1ec7nh van tim v\u00e0 \u0111\u01b0\u1ee3c ph\u00ea duy\u1ec7t nh\u01b0 m\u1ed9t lo\u1ea1i thu\u1ed1c b\u1ed5 sung \u0111\u1ec3 ph\u00f2ng ng\u1eeba th\u1ee9 ph\u00e1t h\u1ed9i ch\u1ee9ng m\u1ea1ch v\u00e0nh c\u1ea5p t\u00ednh v\u00e0 \u0111\u1ed9ng m\u1ea1ch ngo\u1ea1i bi\u00ean.\u00a0<\/span><\/p>\n

\"Xarelto
Xarelto (Rivaroxaban)<\/figcaption><\/figure>\n

Rivaroxaban ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch li\u00ean k\u1ebft tr\u1ef1c ti\u1ebfp v\u00e0 thu\u1eadn ngh\u1ecbch v\u1edbi y\u1ebfu t\u1ed1 Xa th\u00f4ng qua t\u00fai S1 v\u00e0 S4 \u0111\u1ec3 \u1ee9c ch\u1ebf c\u1ea1nh tranh, t\u1eeb \u0111\u00f3 ng\u0103n ch\u1eb7n s\u1ef1 h\u00ecnh th\u00e0nh Thrombin. Rivaroxaban \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a qua gan b\u1edfi enzyme CYP3A4\/5 v\u00e0 CYP2J2, sau \u0111\u00f3 b\u00e0i ti\u1ebft ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u 66% v\u00e0 qua ph\u00e2n 28%.\u00a0<\/span><\/p>\n

Khi s\u1eed d\u1ee5ng Rivaroxaban, t\u00e1c d\u1ee5ng ph\u1ee5 ph\u1ed5 bi\u1ebfn nh\u1ea5t l\u00e0 xu\u1ea5t huy\u1ebft v\u1edbi h\u01a1n 10% tr\u01b0\u1eddng h\u1ee3p, ti\u1ebfp \u0111\u00f3 l\u1ea7n l\u01b0\u1ee3t l\u00e0 ch\u00f3ng m\u1eb7t, m\u1ea5t ng\u1ee7, m\u1ec7t m\u1ecfi, tr\u1ea7m c\u1ea3m, lo l\u1eafng v\u00e0 ng\u1ea5t. M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 hi\u1ebfm g\u1eb7p h\u01a1n nh\u01b0 gi\u00e3n ph\u1ebf qu\u1ea3n, xu\u1ea5t huy\u1ebft ph\u1ed5i, m\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t, s\u1ed1c ph\u1ea3n v\u1ec7, ph\u00f9 m\u1ea1ch, xu\u1ea5t huy\u1ebft n\u00e3o, \u1ee9 m\u1eadt, h\u1ed9i ch\u1ee9ng Dress, h\u1ed9i ch\u1ee9ng Stevens-Johnson<\/span><\/p>\n

Rivaroxaban ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng cho c\u00e1c tr\u01b0\u1eddng h\u1ee3p d\u1ecb \u1ee9ng, suy gan, suy th\u1eadn trung b\u00ecnh, b\u1ec7nh v\u1ec1 van tim, b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 c\u01a1 ch\u1ea3y m\u00e1u cao (r\u1ed1i lo\u1ea1n ch\u1ea3y m\u00e1u b\u1ea9m sinh, lo\u00e9t \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, v\u00f5ng m\u1ea1c m\u1ea1ch m\u00e1u, ti\u1ec1n s\u1eed xu\u1ea5t huy\u1ebft ph\u1ed5i)<\/span><\/p>\n

1.2 T\u00ecm hi\u1ec3u chung v\u1ec1 thu\u1ed1c Eliquis (Apixaban)<\/span><\/h3>\n

Eliquis<\/a>\u00a0(Apixaban) l\u00e0 thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u m\u1edbi \u0111\u01b0\u1eddng u\u1ed1ng (NOAC) thu\u1ed1c nh\u00f3m \u1ee9c ch\u1ebf y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u Xa \u0111\u01b0\u1ee3c FDA ph\u00ea duy\u1ec7t ch\u1ec9 \u0111\u1ecbnh \u1edf s\u1eed d\u1ee5ng cho b\u1ec7nh nh\u00e2n rung t\u00e2m nh\u0129 kh\u00f4ng do b\u1ec7nh van tim nh\u1eb1m gi\u1ea3m nguy c\u01a1 \u0111\u1ed9t qu\u1ef5 v\u00e0 c\u1ee5c m\u00e1u \u0111\u00f4ng.\u00a0<\/span><\/p>\n

\"Eliquis
Eliquis (Apixaban) (c\u00e1i h\u00ecnh n\u00f3 b\u1ecb d\u00ednh ch\u1eef n\u00e0y n\u00e8, thay \u0111\u01b0\u1ee3c h\u00ecnh kh\u00e1c th\u00ec thay nhoa)<\/figcaption><\/figure>\n

Apixaban l\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf tr\u1ef1c ti\u1ebfp y\u1ebfu t\u1ed1 Xa c\u00f3 t\u00ednh ch\u1ecdn l\u1ecdc cao, ng\u0103n ch\u1eb7n giai \u0111o\u1ea1n lan truy\u1ec1n c\u1ee7a chu\u1ed7i \u0111\u00f4ng m\u00e1u. N\u00f3 ph\u00e1t huy t\u00e1c d\u1ee5ng c\u1ee7a n\u00f3 \u0111\u1ed1i v\u1edbi c\u1ea3 y\u1ebfu t\u1ed1 Xa t\u1ef1 do v\u00e0 y\u1ebfu t\u1ed1 li\u00ean k\u1ebft v\u1edbi c\u1ee5c m\u00e1u \u0111\u00f4ng. \u0110\u1ed1i v\u1edbi ho\u1ea1t \u0111\u1ed9ng ch\u1ed1ng huy\u1ebft kh\u1ed1i, n\u00f3 kh\u00f4ng c\u1ea7n Antithrombin III. Y\u1ebfu t\u1ed1 Xa l\u00e0 ch\u1ea5t x\u00fac t\u00e1c \u0111\u1ec3 chuy\u1ec3n \u0111\u1ed5i Prothrombin th\u00e0nh Thrombin, \u0111\u00e2y l\u00e0 b\u01b0\u1edbc cu\u1ed1i c\u00f9ng trong chu\u1ed7i \u0111\u00f4ng m\u00e1u d\u1eabn \u0111\u1ebfn h\u00ecnh th\u00e0nh fibrin v\u00e0 c\u1ee5c m\u00e1u \u0111\u00f4ng<\/span><\/p>\n

Apixaban \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu qua enzyme CYP3A4, sau \u0111\u00f3 25% li\u1ec1u d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua n\u01b0\u1edbc ti\u1ec3u v\u00e0 ph\u00e2n d\u01b0\u1edbi d\u1ea1ng ch\u1ea5t chuy\u1ec3n h\u00f3a<\/span><\/p>\n

L\u00e0 thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u, t\u00e1c d\u1ee5ng ph\u1ee5 ph\u1ed5 bi\u1ebfn nh\u1ea5t c\u1ee7a Apixaban l\u00e0 ch\u1ea3y m\u00e1u (1-10%). Trong \u0111\u00f3, nguy c\u01a1 ch\u1ea3y m\u00e1u n\u1eb7ng l\u00e0 3% v\u00e0 ch\u1ea3y m\u00e1u kh\u00f4ng nghi\u00eam tr\u1ecdng l\u00e0 2 \u2013 4%. C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 \u00edt ph\u1ed5 bi\u1ebfn kh\u00e1c bao g\u1ed3m bu\u1ed3n n\u00f4n (3%), xu\u1ea5t huy\u1ebft n\u01b0\u1edbu (1%), xu\u1ea5t huy\u1ebft \u0111\u01b0\u1eddng ni\u1ec7u (2%)<\/span><\/p>\n

Apixaban \u0111\u01b0\u1ee3c ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed qu\u00e1 m\u1eabn nghi\u00eam tr\u1ecdng<\/span><\/p>\n

2.Nh\u1eefng \u0111i\u1ec3m t\u01b0\u01a1ng \u0111\u1ed3ng gi\u1eefa Xarelto (Rivaroxaban) v\u00e0 Eliquis (Apixaban)<\/strong><\/h2>\n

Xarelto (rivaroxaban) v\u00e0 Eliquis (apixaban) \u0111\u1ec1u l\u00e0 nh\u1eefng thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u m\u1edbi l\u00e0m cho m\u00e1u \u00edt c\u00f3 kh\u1ea3 n\u0103ng \u0111\u00f4ng l\u1ea1i. C\u1ea3 hai \u0111\u1ec1u thu\u1ed9c nh\u00f3m thu\u1ed1c \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf y\u1ebfu t\u1ed1 Xa (FXa)<\/span><\/p>\n

Ngo\u00e0i ra, c\u1ea3 hai thu\u1ed1c Xarelto v\u00e0 Eliquis \u0111\u1ec1u \u0111\u01b0\u1ee3c FDA ph\u00ea duy\u1ec7t s\u1eed d\u1ee5ng trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p sau<\/span><\/p>\n

    \n
  • Gi\u1ea3m nguy c\u01a1 \u0111\u1ed9t qu\u1ef5 v\u00e0 h\u00ecnh th\u00e0nh c\u1ee5c m\u00e1u \u0111\u00f4ng \u1edf ng\u01b0\u1eddi l\u1edbn b\u1ecb rung t\u00e2m nh\u0129 kh\u00f4ng do b\u1ec7nh van tim (AFib)<\/span><\/li>\n
  • \u0110i\u1ec1u tr\u1ecb huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch s\u00e2u (DVT) ho\u1eb7c thuy\u00ean t\u1eafc ph\u1ed5i (PE)\u00a0<\/span><\/li>\n
  • Gi\u1ea3m nguy c\u01a1 DVT ho\u1eb7c PE \u1edf ng\u01b0\u1eddi l\u1edbn \u0111\u00e3 t\u1eebng c\u00f3 ti\u1ec1n s\u1eed b\u1ec7nh li\u00ean quan \u0111\u1ebfn m\u00e1u \u0111\u00f4ng<\/span><\/li>\n
  • Gi\u1ea3m nguy c\u01a1 m\u1eafc DVT \u1edf ng\u01b0\u1eddi l\u1edbn \u0111\u01b0\u1ee3c thay kh\u1edbp g\u1ed1i ho\u1eb7c kh\u1edbp h\u00e1ng\u00a0<\/span><\/li>\n
  • Gi\u1ea3m nguy c\u01a1 h\u00ecnh th\u00e0nh huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch (VTE) \u1edf ng\u01b0\u1eddi l\u1edbn trong ho\u1eb7c sau khi \u0111i\u1ec1u tr\u1ecb t\u1ea1i b\u1ec7nh vi\u1ec7n\u00a0<\/span><\/li>\n
  • Gi\u1ea3m nguy c\u01a1 m\u1eafc c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 tim v\u00e0 m\u1ea1ch m\u00e1u \u1edf ng\u01b0\u1eddi l\u1edbn m\u1eafc b\u1ec7nh \u0111\u1ed9ng m\u1ea1ch v\u00e0nh (CAD)<\/span><\/li>\n
  • Gi\u1ea3m nguy c\u01a1 \u0111\u00f4ng m\u00e1u \u1edf ng\u01b0\u1eddi l\u1edbn m\u1eafc b\u1ec7nh \u0111\u1ed9ng m\u1ea1ch ngo\u1ea1i bi\u00ean (PAD)<\/span><\/li>\n<\/ul>\n

    3.Nh\u1eefng \u0111i\u1ec3m kh\u00e1c bi\u1ec7t gi\u1eefa Xarelto (Rivaroxaban) v\u00e0 Eliquis (Apixaban)<\/strong><\/h2>\n

    3.1 M\u1ee5c \u0111\u00edch v\u00e0 \u0111\u1ed1i t\u01b0\u1ee3ng s\u1eed d\u1ee5ng thu\u1ed1c\u00a0<\/span><\/h3>\n

    Eliquis v\u00e0 Xarelto \u0111\u1ec1u l\u00e0 l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb \u0111\u1ea7u ti\u00ean \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb v\u00e0 ng\u0103n ng\u1eeba huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch s\u00e2u ho\u1eb7c thuy\u00ean t\u1eafc ph\u1ed5i. Tuy v\u1eady, t\u00f9y v\u00e0o m\u1ee5c \u0111\u00edch s\u1eed d\u1ee5ng v\u00e0 \u0111\u1ed1i t\u01b0\u1ee3ng d\u00f9ng thu\u1ed1c m\u00e0 c\u00f3 s\u1ef1 kh\u00e1c bi\u1ec7t nh\u01b0 sau:<\/span><\/p>\n

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    • B\u1ec7nh nh\u00e2n c\u00f3 v\u1ea5n \u0111\u1ec1 v\u1ec1 th\u1eadn: Eliquis l\u00e0 l\u1ef1a ch\u1ecdn t\u1ed1t h\u01a1n\u00a0<\/span><\/li>\n
    • B\u1ec7nh nh\u00e2n hay qu\u00ean u\u1ed1ng thu\u1ed1c: Xarelto t\u1ed1i \u01b0u h\u01a1n v\u00ec c\u00f3 th\u1ec3 u\u1ed1ng m\u1ed9t l\u1ea7n m\u1ed7i ng\u00e0y<\/span><\/li>\n
    • B\u1ec7nh nh\u00e2n l\u00e0 tr\u1ebb em: Xarelto \u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn cho c\u00e1c m\u1ee5c \u0111\u00edch s\u1eed d\u1ee5ng (\u0111i\u1ec1u tr\u1ecb VTE, gi\u1ea3m nguy c\u01a1 VTE,…)<\/span><\/li>\n<\/ul>\n

      3.2 T\u00e1c d\u1ee5ng ph\u1ee5\u00a0<\/span><\/h3>\n

      T\u00e1c d\u1ee5ng nh\u1eb9\u00a0<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
      T\u00e1c d\u1ee5ng ph\u1ee5<\/b><\/td>\nXarelto<\/b><\/td>\nEliquis<\/b><\/td>\n<\/tr>\n
      Thi\u1ebfu m\u00e1u (m\u1ee9c h\u1ed3ng c\u1ea7u th\u1ea5p)\u00a0<\/span><\/td>\n<\/td>\n\u2713<\/span><\/td>\n<\/tr>\n
      \u0110au l\u01b0ng<\/span><\/td>\n\u2713<\/span><\/td>\n<\/td>\n<\/tr>\n
      \u0110au b\u1ee5ng\u00a0<\/span><\/td>\n\u2713<\/span><\/td>\n<\/td>\n<\/tr>\n
      Ch\u00f3ng m\u1eb7t<\/span><\/td>\n\u2713<\/span><\/td>\n<\/td>\n<\/tr>\n
      M\u1ec7t m\u1ecfi (n\u0103ng l\u01b0\u1ee3ng th\u1ea5p)\u00a0<\/span><\/td>\n\u2713<\/span><\/td>\n<\/td>\n<\/tr>\n
      Ng\u1ee9a ng\u00e1y<\/span><\/td>\n\u2713<\/span><\/td>\n<\/td>\n<\/tr>\n
      B\u1ea7m t\u00edm nh\u1eb9\u00a0<\/span><\/td>\n\u2713<\/span><\/td>\n\u2713<\/span><\/td>\n<\/tr>\n
      Chu\u1ed9t r\u00fat c\u01a1 b\u1eafp<\/span><\/td>\n\u2713<\/span><\/td>\n<\/td>\n<\/tr>\n
      Bu\u1ed3n n\u00f4n<\/span><\/td>\n<\/td>\n\u2713<\/span><\/td>\n<\/tr>\n
      Kh\u00f3 ng\u1ee7<\/span><\/td>\n\u2713<\/span><\/td>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

      T\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng\u00a0<\/span><\/p>\n\n\n\n\n\n\n\n\n
      T\u00e1c d\u1ee5ng ph\u1ee5<\/b><\/td>\nXarelto<\/b><\/td>\nEliquis<\/b><\/td>\n<\/tr>\n
      Nguy c\u01a1 \u0111\u00f4ng m\u00e1u t\u00edch t\u1ee5 \u1edf c\u1ed9t s\u1ed1ng<\/span><\/td>\n\u2713<\/span><\/td>\n\u2713<\/span><\/td>\n<\/tr>\n
      Nguy c\u01a1 h\u00ecnh th\u00e0nh m\u00e1u \u0111\u00f4ng khi \u0111\u1ed9t ng\u1ed9t ng\u1eebng thu\u1ed1c<\/span><\/td>\n\u2713<\/span><\/td>\n\u2713<\/span><\/td>\n<\/tr>\n
      \u1ea2nh h\u01b0\u1edfng s\u1ee9c kh\u1ecfe t\u00e2m th\u1ea7n (tr\u1ea7m c\u1ea3m, lo \u00e2u)<\/span><\/td>\n\u2713<\/span><\/td>\n<\/td>\n<\/tr>\n
      Ch\u1ea3y m\u00e1u nghi\u00eam tr\u1ecdng\u00a0<\/span><\/td>\n\u2713<\/span><\/td>\n\u2713<\/span><\/td>\n<\/tr>\n
      Ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng nghi\u00eam tr\u1ecdng\u00a0<\/span><\/td>\n\u2713<\/span><\/td>\n\u2713<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

      3.3 Li\u1ec1u d\u00f9ng<\/span><\/h3>\n

      Trong ph\u00f2ng ng\u1eeba c\u1ee5c m\u00e1u \u0111\u00f4ng v\u00e0 \u0111\u1ed9t qu\u1ef5 v\u1edbi AFib<\/span><\/p>\n

        \n
      • Xarelto: vi\u00ean n\u00e9n 15mg ho\u1eb7c 20mg x 1 l\u1ea7n\/ng\u00e0y\u00a0<\/span><\/li>\n
      • Eliquis: vi\u00ean n\u00e9n 5mg x 2 l\u1ea7n\/ng\u00e0y\u00a0<\/span><\/li>\n<\/ul>\n

        Trong \u0111i\u1ec1u tr\u1ecb DVT ho\u1eb7c PE<\/span><\/p>\n

          \n
        • Xarelto: li\u1ec1u kh\u1edfi \u0111\u1ea7u 15mg x 2 l\u1ea7n\/ng\u00e0y trong 21 ng\u00e0y v\u00e0 li\u1ec1u duy tr\u00ec 20mg x 1 l\u1ea7n\/ng\u00e0y<\/span><\/li>\n
        • Eliquis: li\u1ec1u kh\u1edfi \u0111\u1ea7u 10mg x 2 l\u1ea7n\/ng\u00e0y trong 7 ng\u00e0y v\u00e0 li\u1ec1u duy tr\u00ec 5mg x 2 l\u1ea7n\/ng\u00e0y<\/span><\/li>\n<\/ul>\n

          Trong ph\u00f2ng ng\u1eeba DVT ho\u1eb7c PE sau \u0111i\u1ec1u tr\u1ecb\u00a0<\/span><\/p>\n

            \n
          • Xarelto: vi\u00ean n\u00e9n 10mg x 1 l\u1ea7n\/ng\u00e0y\u00a0<\/span><\/li>\n
          • Eliquis: vi\u00ean n\u00e9n 2,5mg x 2 l\u1ea7n\/ng\u00e0y<\/span><\/li>\n<\/ul>\n

            Trong ph\u00f2ng ng\u1eeba DVT ho\u1eb7c PE sau khi thay kh\u1edbp h\u00e1ng ho\u1eb7c kh\u1edbp g\u1ed1i<\/span><\/p>\n

              \n
            • Xarelto: vi\u00ean n\u00e9n 10mg x 1 l\u1ea7n\/ng\u00e0y<\/span><\/li>\n
            • Eliquis: vi\u00ean n\u00e9n 2,5mg x 2 l\u1ea7n\/ng\u00e0y<\/span><\/li>\n<\/ul>\n

               <\/p>\n","protected":false},"excerpt":{"rendered":"

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