{"id":27577,"date":"2023-04-23T21:43:35","date_gmt":"2023-04-23T14:43:35","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=27577"},"modified":"2023-04-23T21:43:35","modified_gmt":"2023-04-23T14:43:35","slug":"thuoc-spironolactone","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/23\/thuoc-spironolactone\/","title":{"rendered":"Thu\u1ed1c spironolactone trong \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n"},"content":{"rendered":"<p><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Thu\u1ed1c \u1ee9c ch\u1ebf h\u1ea5p th\u1ee5 Mineralocorticoid (MRA)- <\/span><\/span><\/strong><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">spironolactone <\/span><\/span><\/strong><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n t\u00ednh, \u0111\u1eb7c bi\u1ec7t l\u00e0 suy tim n\u1eb7ng. <\/span><span style=\"vertical-align: inherit;\">Thu\u1ed1c n\u00e0y c\u00f3 t\u00e1c d\u1ee5ng ch\u00ednh l\u00e0 ch\u1ebf \u0111\u1ed9 h\u1ea5p th\u1ee5 aldosterone, m\u1ed9t lo\u1ea1i hormone c\u00f3 t\u00e1c d\u1ee5ng gi\u1eef n\u01b0\u1edbc v\u00e0 mu\u1ed1i trong c\u01a1 th\u1ec3. <\/span><span style=\"vertical-align: inherit;\">Khi t\u0103ng aldosterone trong suy tim, n\u00f3 c\u00f3 th\u1ec3 g\u00e2y t\u0103ng co m\u1ea1ch, xung \u0111\u1ea1i c\u01a1 tim, suy th\u1eadn v\u00e0 r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng n\u1ed9i m\u1ea1c.<\/span><\/span><\/strong><\/p>\n<h2><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">1.Gi\u1edbi thi\u1ec7u<\/span><\/span><\/h2>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c MRA c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng th\u00e1i qu\u00e1 c\u1ee7a aldosterone trong suy tim n\u1eb7ng, do \u0111\u00f3 gi\u00fap gi\u1ea3m co m\u1ea1ch \u0111\u1ed3ng th\u1eddi v\u1edbi t\u00ecnh tr\u1ea1ng gi\u1eef n\u01b0\u1edbc, ph\u1ebft \u0111\u1ea1i c\u01a1 tim, suy th\u1eadn v\u00e0 r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng n\u1ed9i m\u1ea1c. <\/span><span style=\"vertical-align: inherit;\">Ngo\u00e0i ra, thu\u1ed1c n\u00e0y c\u00f2n c\u00f3 t\u00e1c d\u1ee5ng l\u1ee3i ti\u1ec3u, gi\u00fap gi\u1ea3m \u00e1p l\u1ef1c l\u00ean tim.<\/span><\/span><\/p>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">C\u00f3 nhi\u1ec1u nghi\u00ean c\u1ee9u \u0111\u00e3 ch\u1ee9ng minh r\u1eb1ng s\u1eed d\u1ee5ng thu\u1ed1c MRA c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u1ef7 l\u1ec7 t\u1eed vong v\u00e0 nh\u1eadp vi\u1ec7n \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n suy tim n\u1eb7ng.<\/span><\/span><\/p>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Tuy nhi\u00ean, vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c MRA c\u0169ng c\u00f3 m\u1ed9t s\u1ed1 ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh v\u00e0 th\u1eadn tr\u1ecdng, nh\u01b0 suy th\u1eadn n\u1eb7ng v\u00e0 t\u0103ng kali m\u00e1u. <\/span><span style=\"vertical-align: inherit;\">Vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c n\u00e0y c\u1ea7n \u0111\u01b0\u1ee3c quan s\u00e1t v\u00e0 \u0111\u00e1nh gi\u00e1 k\u1ef9 c\u00e0ng b\u1edfi b\u00e1c s\u0129 chuy\u00ean m\u00f4n \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 trong \u0111i\u1ec1u tr\u1ecb suy tim.<\/span><\/span><\/p>\n<h2><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">2. Thu\u1ed1c spironolactone<\/span><\/span><\/h2>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Spironolactone l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 mineralocorticoid (MRA), \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb nhi\u1ec1u b\u1ec7nh nh\u01b0 suy tim m\u1ea1n, huy\u1ebft \u00e1p cao, t\u0103ng androgen n\u1eef v\u00e0 t\u0103ng aldosterone. <\/span><span style=\"vertical-align: inherit;\">L\u01b0\u1ee3ng thu\u1ed1c ph\u1ee5 thu\u1ed9c v\u00e0o t\u00ecnh tr\u1ea1ng s\u1ee9c kh\u1ecfe c\u1ee7a b\u1ec7nh nh\u00e2n v\u00e0 \u0111\u01b0\u1ee3c quy\u1ebft \u0111\u1ecbnh b\u1edfi b\u00e1c s\u0129 chuy\u00ean khoa.<\/span><\/span><\/p>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Theo th\u00f4ng tin trong c\u00e2u h\u1ecfi c\u1ee7a b\u1ea1n, hi\u1ec7n t\u1ea1i c\u00f3 hai li\u1ec1u l\u01b0\u1ee3ng c\u1ee7a thu\u1ed1c Spironolactone \u0111\u01b0\u1ee3c \u0111\u1ec1 c\u1eadp l\u00e0 25mg\/ng\u00e0y v\u00e0 50mg\/ng\u00e0y. <\/span><span style=\"vertical-align: inherit;\">Tuy nhi\u00ean, \u0111\u1ec3 s\u1eed d\u1ee5ng thu\u1ed1c m\u1ed9t c\u00e1ch \u0111\u00fang \u0111\u1eafn, b\u1ea1n c\u1ea7n tu\u00e2n theo h\u01b0\u1edbng d\u1eabn ch\u00ednh x\u00e1c c\u1ee7a th\u1ee7 thu\u1eadt s\u1eed d\u1ee5ng c\u1ee7a b\u00e1c s\u0129 v\u00e0\/ho\u1eb7c h\u01b0\u1edbng d\u1eabn tr\u00ean nh\u00e3n c\u1ee7a s\u1ea3n ph\u1ea9m.<\/span><\/span><\/p>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Th\u00f4ng th\u01b0\u1eddng, kh\u1edfi \u0111\u1ea7u c\u1ee7a thu\u1ed1c Spironolactone \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb suy tim l\u00e0 25mg\/ng\u00e0y, t\u0103ng d\u1ea7n l\u00ean 50\/ng\u00e0y n\u1ebfu c\u1ea7n thi\u1ebft. <\/span><span style=\"vertical-align: inherit;\">Tuy nhi\u00ean, m\u1ee9c t\u1ed1i \u01b0u c\u1ee7a thu\u1ed1c ph\u1ee5 thu\u1ed9c v\u00e0o t\u00ecnh tr\u1ea1ng s\u1ee9c kh\u1ecfe c\u1ee7a b\u1ec7nh nh\u00e2n v\u00e0 c\u00f3 th\u1ec3 kh\u00e1c nhau \u0111\u1ed1i v\u1edbi t\u1eebng tr\u01b0\u1eddng h\u1ee3p c\u1ee5 th\u1ec3. <\/span><span style=\"vertical-align: inherit;\">V\u00ec v\u1eady, b\u1ea1n n\u00ean tham kh\u1ea3o \u00fd ki\u1ebfn \u200b\u200bb\u00e1c s\u0129 \u0111\u1ec3 bi\u1ebft \u0111\u01b0\u1ee3c khen l\u01b0\u1ee3ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng \u0111\u00fang \u0111\u1eafn cho t\u1eebng tr\u01b0\u1eddng h\u1ee3p c\u1ee5 th\u1ec3.<\/span><\/span><\/p>\n<h2><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">3. C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5<\/span><\/span><\/h2>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Thu\u1ed1c Spironolactone c\u00f3 th\u1ec3 g\u00e2y ra m\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5, tuy nhi\u00ean kh\u00f4ng ph\u1ea3i t\u1ea5t c\u1ea3 c\u00e1c b\u1ec7nh nh\u00e2n \u0111\u1ec1u g\u1eb7p ph\u1ea3i. <\/span><span style=\"vertical-align: inherit;\">C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p c\u1ee7a thu\u1ed1c bao g\u1ed3m:<\/span><\/span><\/p>\n<ul>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">T\u0103ng kali m\u00e1u: Thu\u1ed1c Spironolactone c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 aldosterone, do \u0111\u00f3 c\u00f3 th\u1ec3 l\u00e0m t\u0103ng kali m\u00e1u \u1edf m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n. <\/span><span style=\"vertical-align: inherit;\">\u0110i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 bu\u1ed3n n\u00f4n, ti\u1ec3u \u0111\u00eam, m\u1ec7t m\u1ecfi, \u0111au \u0111\u1ea7u v\u00e0 r\u1ed1i lo\u1ea1n nh\u1ecbp tim n\u1ebfu kali m\u00e1u t\u0103ng qu\u00e1 cao.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">M\u1ea5t c\u00e2n b\u1eb1ng \u0111i\u1ec7n gi\u1ea3i: Thu\u1ed1c Spironolactone c\u0169ng c\u00f3 th\u1ec3 g\u00e2y m\u1ea5t c\u00e2n b\u1eb1ng \u0111i\u1ec7n gi\u1ea3i, bao g\u1ed3m t\u0103ng kali m\u00e1u, gi\u1ea3m natri v\u00e0 gi\u1ea3m magie. <\/span><span style=\"vertical-align: inherit;\">\u0110i\u1ec1u tr\u1ecb n\u00e0y c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 \u0111au \u0111\u1ea7u, bu\u1ed3n n\u00f4n, kh\u00e1t n\u01b0\u1edbc, m\u1ea5t c\u1ea3m gi\u00e1c, co gi\u1eadt v\u00e0 r\u1ed1i lo\u1ea1n nh\u1ecbp tim.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Thay \u0111\u1ed5i hormone: Thu\u1ed1c Spironolactone c\u0169ng c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf ho\u1ea1t \u0111\u1ed9ng c\u1ee7a hormone androgen, do \u0111\u00f3 c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nh\u01b0 gi\u1ea3m sinh l\u00fd, t\u0103ng k\u00edch th\u01b0\u1edbc v\u00fa v\u00e0 gi\u1ea3m s\u1ea3n xu\u1ea5t tinh tr\u00f9ng \u1edf nam gi\u1edbi. <\/span><span style=\"vertical-align: inherit;\">\u1ede ph\u1ee5 n\u1eef, thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nh\u01b0 r\u1ee5ng t\u00f3c, t\u0103ng kh\u1ea3 n\u0103ng ph\u00e1t tri\u1ec3n t\u1ebf b\u00e0o s\u1eebng v\u00e0 t\u0103ng s\u1ea3n xu\u1ea5t hormone estrogen.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">T\u00e1c d\u1ee5ng tr\u00ean ti\u00eau h\u00f3a: Thu\u1ed1c Spironolactone c\u0169ng c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean ti\u00eau h\u00f3a, bao g\u1ed3m bu\u1ed3n n\u00f4n, ti\u00eau ch\u1ea3y, n\u1ed1t ru\u1ed3i v\u00e0 \u0111\u1ea7y h\u01a1i.<\/span><\/span><\/li>\n<\/ul>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">N\u1ebfu g\u1eb7p b\u1ea5t k\u1ef3 t\u00e1c d\u1ee5ng ph\u1ee5 n\u00e0o khi s\u1eed d\u1ee5ng thu\u1ed1c Spironolactone, b\u1ea1n n\u00ean th\u00f4ng b\u00e1o cho b\u00e1c s\u0129 ngay l\u1eadp t\u1ee9c \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n v\u00e0 \u0111i\u1ec1u tr\u1ecb k\u1ecbp th\u1eddi.<\/span><\/span><\/p>\n<h2><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">4. Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh<\/span><\/span><\/h2>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Thu\u1ed1c Spironolactone c\u00f3 m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng, bao g\u1ed3m:<\/span><\/span><\/p>\n<ul>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Qu\u00e1 kh\u1ea3 n\u0103ng c\u1ea3m nh\u1eadn v\u1edbi th\u00e0nh ph\u1ea7n c\u1ee7a thu\u1ed1c.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">T\u0103ng kali m\u00e1u nghi\u00eam tr\u1ecdng.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Suy th\u1eadn tr\u1ecdng.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Suy gan n\u1eb7ng.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">T\u1eafc \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u.<\/span><\/span><\/li>\n<\/ul>\n<h2><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">5. T\u01b0\u01a1ng t\u00e1c thu\u1ed1c c\u1ee7a Spironolactone<\/span><\/span><\/h2>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">D\u01b0\u1edbi \u0111\u00e2y l\u00e0 m\u1ed9t s\u1ed1 th\u00f4ng tin chi ti\u1ebft h\u01a1n v\u1ec1 c\u00e1c t\u01b0\u01a1ng t\u00e1c n\u00e0y:<\/span><\/span><\/p>\n<ul>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Salicylate: Salicylate c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng c\u00f3 l\u1ee3i c\u1ee7a Spironolactone \u0111\u1ed1i v\u1edbi t\u00e1c d\u1ee5ng gi\u1ea3m huy\u1ebft \u00e1p.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">C\u00e1c lo\u1ea1i thu\u1ed1c b\u1ed5 sung kh\u00e1c: S\u1eed d\u1ee5ng Spironolactone c\u00f9ng v\u1edbi c\u00e1c lo\u1ea1i thu\u1ed1c b\u1ed5 sung kh\u00e1c c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn t\u0103ng l\u01b0\u1ee3ng n\u01b0\u1edbc th\u1ea3i v\u00e0 g\u00e2y m\u1ea5t c\u00e2n b\u1eb1ng \u0111i\u1ec7n gi\u1ea3i.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Kali v\u00e0 c\u00e1c thu\u1ed1c l\u1ee3i ti\u1ec3u gi\u1eef kali kh\u00e1c: S\u1eed d\u1ee5ng Spironolactone c\u00f9ng v\u1edbi c\u00e1c thu\u1ed1c gi\u1eef kali ho\u1eb7c c\u00e1c thu\u1ed1c l\u1ee3i ti\u1ec3u c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn t\u0103ng kali huy\u1ebft v\u00e0 g\u00e2y nguy hi\u1ec3m cho t\u00ednh m\u1ea1ng.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Thu\u1ed1c ch\u1ed1ng t\u0103ng huy\u1ebft \u00e1p: S\u1eed d\u1ee5ng Spironolactone c\u00f9ng v\u1edbi thu\u1ed1c ch\u1ed1ng t\u0103ng huy\u1ebft \u00e1p c\u00f3 th\u1ec3 t\u0103ng t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Thu\u1ed1c kh\u00e1ng vi\u00eam kh\u00e1ng steroid NSAID: S\u1eed d\u1ee5ng Spironolactone c\u00f9ng v\u1edbi thu\u1ed1c kh\u00e1ng vi\u00eam kh\u00e1ng steroid NSAID c\u00f3 th\u1ec3 l\u00e0m t\u0103ng kali huy\u1ebft v\u00e0 g\u00e2y nguy hi\u1ec3m \u0111\u1ebfn t\u00ednh m\u1ea1ng.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Thu\u1ed1c \u1ee9c ch\u1ebf enzym chuy\u1ec3n ongiolensin: S\u1eed d\u1ee5ng Spironolactone c\u00f9ng v\u1edbi thu\u1ed1c \u1ee9c ch\u1ebf enzym chuy\u1ec3n ongiolensin c\u00f3 th\u1ec3 l\u00e0m t\u0103ng kali huy\u1ebft v\u00e0 g\u00e2y nguy hi\u1ec3m \u0111\u1ebfn t\u00ednh m\u1ea1ng.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Amoni clorid: S\u1eed d\u1ee5ng Spironolactone c\u00f9ng v\u1edbi amoni clorid c\u00f3 nguy\u00ean c\u01a1 t\u0103ng to\u00e0n huy\u1ebft.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Fludrocortisone: S\u1eed d\u1ee5ng Spironolactone c\u00f9ng v\u1edbi Fludrocortisone c\u00f3 th\u1ec3 t\u0103ng th\u1ea3i tr\u1eeb kali m\u1ed9t c\u00e1ch b\u1ea5t th\u01b0\u1eddng.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Digoxin: S\u1eed d\u1ee5ng Spironolactone c\u00f9ng v\u1edbi Digoxin c\u00f3 th\u1ec3 l\u00e0m t\u0103ng th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a Digoxin v\u00e0 g\u00e2y ra nguy c\u01a1 nhi\u1ec5m \u0111\u1ed9c Digoxin..<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">C\u00e1c d\u1eabn xu\u1ea5t coumorine: S\u1eed d\u1ee5ng Spironolactone gi\u1ed1ng v\u1edbi c\u00e1c d\u1eabn xu\u1ea5t coumorine c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng c\u1ee7a c\u00e1c d\u1eabn xu\u1ea5t n\u00e0y.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Carbenoxolone: \u200b\u200bS\u1eed d\u1ee5ng Spironolactone c\u00f9ng v\u1edbi Carbenoxolone c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a Carbenoxolone.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Neomycin: S\u1eed d\u1ee5ng Spironolactone c\u00f9ng v\u1edbi Neomycin c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m h\u1ea5p thu c\u1ee7a Spironolactone.<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Wiploreline, busereline, gonodoreline: S\u1eed d\u1ee5ng Spironolactone c\u00f9ng v\u1edbi c\u00e1c lo\u1ea1i thu\u1ed1c n\u00e0y \u0111\u1ec3 c\u00f3 th\u1ec3 t\u0103ng t\u00e1c d\u1ee5ng c\u1ee7a nh\u1eefng lo\u1ea1i thu\u1ed1c n\u00e0y.<\/span><\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c \u1ee9c ch\u1ebf h\u1ea5p th\u1ee5 Mineralocorticoid (MRA)- spironolactone l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n t\u00ednh, \u0111\u1eb7c bi\u1ec7t l\u00e0 suy tim n\u1eb7ng. Thu\u1ed1c n\u00e0y c\u00f3 t\u00e1c d\u1ee5ng ch\u00ednh l\u00e0 ch\u1ebf \u0111\u1ed9 h\u1ea5p th\u1ee5 aldosterone, m\u1ed9t lo\u1ea1i hormone c\u00f3 t\u00e1c d\u1ee5ng gi\u1eef n\u01b0\u1edbc v\u00e0 mu\u1ed1i trong c\u01a1 th\u1ec3. Khi t\u0103ng [&hellip;]<\/p>\n","protected":false},"author":25,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[7,33],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Thu\u1ed1c spironolactone trong \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n - Vinmec<\/title>\n<meta name=\"description\" content=\"Thu\u1ed1c spironolactone l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n, \u0111\u1eb7c bi\u1ec7t l\u00e0 suy tim n\u1eb7ng.T\u00e1c d\u1ee5ng l\u00e0 \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 aldosterone\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Thu\u1ed1c spironolactone trong \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n - Vinmec\" \/>\n<meta property=\"og:description\" content=\"Thu\u1ed1c spironolactone l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n, \u0111\u1eb7c bi\u1ec7t l\u00e0 suy tim n\u1eb7ng.T\u00e1c d\u1ee5ng l\u00e0 \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 aldosterone\" \/>\n<meta property=\"og:url\" content=\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/23\/thuoc-spironolactone\/\" \/>\n<meta property=\"og:site_name\" content=\"Vinmec\" \/>\n<meta property=\"article:published_time\" content=\"2023-04-23T14:43:35+00:00\" \/>\n<meta name=\"author\" content=\"Thinh Nguyen Hoang\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Thinh Nguyen Hoang\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/23\/thuoc-spironolactone\/\",\"url\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/23\/thuoc-spironolactone\/\",\"name\":\"Thu\u1ed1c spironolactone trong \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n - Vinmec\",\"isPartOf\":{\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/#website\"},\"datePublished\":\"2023-04-23T14:43:35+00:00\",\"dateModified\":\"2023-04-23T14:43:35+00:00\",\"author\":{\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/68301644e785034fdd8106b4c392fa5d\"},\"description\":\"Thu\u1ed1c spironolactone l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n, \u0111\u1eb7c bi\u1ec7t l\u00e0 suy tim n\u1eb7ng.T\u00e1c d\u1ee5ng l\u00e0 \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 aldosterone\",\"breadcrumb\":{\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/23\/thuoc-spironolactone\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/23\/thuoc-spironolactone\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/23\/thuoc-spironolactone\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"http:\/\/noithathoaphat.in\/ctv\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Thu\u1ed1c spironolactone trong \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n\"}]},{\"@type\":\"WebSite\",\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/#website\",\"url\":\"http:\/\/noithathoaphat.in\/ctv\/\",\"name\":\"Vinmec\",\"description\":\"H\u1ec7 th\u1ed1ng Y t\u1ebf Vinmec\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"http:\/\/noithathoaphat.in\/ctv\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/68301644e785034fdd8106b4c392fa5d\",\"name\":\"Thinh Nguyen Hoang\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/image\/\",\"url\":\"http:\/\/2.gravatar.com\/avatar\/eda1569ca1057e665d34a18ba4468cb1?s=96&d=mm&r=g\",\"contentUrl\":\"http:\/\/2.gravatar.com\/avatar\/eda1569ca1057e665d34a18ba4468cb1?s=96&d=mm&r=g\",\"caption\":\"Thinh Nguyen Hoang\"},\"url\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/author\/nguyenhoangthinh1902gmail-com\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Thu\u1ed1c spironolactone trong \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n - Vinmec","description":"Thu\u1ed1c spironolactone l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n, \u0111\u1eb7c bi\u1ec7t l\u00e0 suy tim n\u1eb7ng.T\u00e1c d\u1ee5ng l\u00e0 \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 aldosterone","robots":{"index":"noindex","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"og_locale":"en_US","og_type":"article","og_title":"Thu\u1ed1c spironolactone trong \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n - Vinmec","og_description":"Thu\u1ed1c spironolactone l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n, \u0111\u1eb7c bi\u1ec7t l\u00e0 suy tim n\u1eb7ng.T\u00e1c d\u1ee5ng l\u00e0 \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 aldosterone","og_url":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/23\/thuoc-spironolactone\/","og_site_name":"Vinmec","article_published_time":"2023-04-23T14:43:35+00:00","author":"Thinh Nguyen Hoang","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Thinh Nguyen Hoang","Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/23\/thuoc-spironolactone\/","url":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/23\/thuoc-spironolactone\/","name":"Thu\u1ed1c spironolactone trong \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n - Vinmec","isPartOf":{"@id":"http:\/\/noithathoaphat.in\/ctv\/#website"},"datePublished":"2023-04-23T14:43:35+00:00","dateModified":"2023-04-23T14:43:35+00:00","author":{"@id":"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/68301644e785034fdd8106b4c392fa5d"},"description":"Thu\u1ed1c spironolactone l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n, \u0111\u1eb7c bi\u1ec7t l\u00e0 suy tim n\u1eb7ng.T\u00e1c d\u1ee5ng l\u00e0 \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 aldosterone","breadcrumb":{"@id":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/23\/thuoc-spironolactone\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/23\/thuoc-spironolactone\/"]}]},{"@type":"BreadcrumbList","@id":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/23\/thuoc-spironolactone\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"http:\/\/noithathoaphat.in\/ctv\/"},{"@type":"ListItem","position":2,"name":"Thu\u1ed1c spironolactone trong \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n"}]},{"@type":"WebSite","@id":"http:\/\/noithathoaphat.in\/ctv\/#website","url":"http:\/\/noithathoaphat.in\/ctv\/","name":"Vinmec","description":"H\u1ec7 th\u1ed1ng Y t\u1ebf Vinmec","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"http:\/\/noithathoaphat.in\/ctv\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Person","@id":"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/68301644e785034fdd8106b4c392fa5d","name":"Thinh Nguyen Hoang","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/image\/","url":"http:\/\/2.gravatar.com\/avatar\/eda1569ca1057e665d34a18ba4468cb1?s=96&d=mm&r=g","contentUrl":"http:\/\/2.gravatar.com\/avatar\/eda1569ca1057e665d34a18ba4468cb1?s=96&d=mm&r=g","caption":"Thinh Nguyen Hoang"},"url":"http:\/\/noithathoaphat.in\/ctv\/index.php\/author\/nguyenhoangthinh1902gmail-com\/"}]}},"_links":{"self":[{"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/posts\/27577"}],"collection":[{"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/users\/25"}],"replies":[{"embeddable":true,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/comments?post=27577"}],"version-history":[{"count":1,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/posts\/27577\/revisions"}],"predecessor-version":[{"id":27580,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/posts\/27577\/revisions\/27580"}],"wp:attachment":[{"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/media?parent=27577"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/categories?post=27577"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/tags?post=27577"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}