{"id":25791,"date":"2023-04-22T22:37:44","date_gmt":"2023-04-22T15:37:44","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=25791"},"modified":"2023-04-22T22:37:44","modified_gmt":"2023-04-22T15:37:44","slug":"tuong-tac-thuoc-giua-naproxen-va-ibuprofen","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/22\/tuong-tac-thuoc-giua-naproxen-va-ibuprofen\/","title":{"rendered":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Naproxen v\u00e0 Ibuprofen"},"content":{"rendered":"<p><strong>Naproxen v\u00e0 Ibuprofen l\u00e0 hai lo\u1ea1i thu\u1ed1c NSAIDs ph\u1ed5 bi\u1ebfn \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 gi\u1ea3m \u0111au v\u00e0 vi\u00eam trong \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd nh\u01b0 \u0111au \u0111\u1ea7u, \u0111au l\u01b0ng v\u00e0 vi\u00eam kh\u1edbp. Tuy nhi\u00ean, khi \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi, ch\u00fang c\u00f3 th\u1ec3 g\u00e2y ra t\u01b0\u01a1ng t\u00e1c thu\u1ed1c, l\u00e0m t\u0103ng nguy c\u01a1 c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nh\u01b0 \u0111au d\u1ea1 d\u00e0y, ch\u1ea3y m\u00e1u ti\u00eau h\u00f3a v\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5 \u0111\u1ed1i v\u1edbi th\u1eadn. Trong b\u00e0i vi\u1ebft n\u00e0y, ch\u00fang ta s\u1ebd \u0111i s\u00e2u v\u00e0o c\u01a1 ch\u1ebf t\u01b0\u01a1ng t\u00e1c, c\u00e1c d\u1ea5u hi\u1ec7u c\u1ea3nh b\u00e1o v\u00e0 c\u00e1ch qu\u1ea3n l\u00fd t\u01b0\u01a1ng t\u00e1c thu\u1ed1c n\u00e0y \u0111\u1ec3 gi\u1ea3m thi\u1ec3u t\u00e1c d\u1ee5ng ph\u1ee5 cho b\u1ec7nh nh\u00e2n.<\/strong><\/p>\n<h2><strong>1.Gi\u1edbi thi\u1ec7u chung\u00a0<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">T\u01b0\u01a1ng t\u00e1c thu\u1ed1c l\u00e0 nh\u1eefng thay \u0111\u1ed5i v\u1ec1 t\u00e1c d\u1ee5ng c\u1ee7a m\u1ed9t lo\u1ea1i thu\u1ed1c do vi\u1ec7c s\u1eed d\u1ee5ng m\u1ed9t ho\u1eb7c nhi\u1ec1u lo\u1ea1i thu\u1ed1c kh\u00e1c g\u1ea7n \u0111\u00e2y ho\u1eb7c \u0111\u1ed3ng th\u1eddi (t\u01b0\u01a1ng t\u00e1c thu\u1ed1c-thu\u1ed1c), \u0103n v\u00e0o th\u1ee9c \u0103n (t\u01b0\u01a1ng t\u00e1c thu\u1ed1c-dinh d\u01b0\u1ee1ng ) ho\u1eb7c \u0103n th\u1ef1c ph\u1ea9m b\u1ed5 sung (t\u01b0\u01a1ng t\u00e1c thu\u1ed1c-b\u1ed5 sung ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng). T\u01b0\u01a1ng t\u00e1c thu\u1ed1c-thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m t\u0103ng ho\u1eb7c gi\u1ea3m t\u00e1c d\u1ee5ng c\u1ee7a m\u1ed9t ho\u1eb7c c\u1ea3 hai lo\u1ea1i thu\u1ed1c. C\u00e1c t\u01b0\u01a1ng t\u00e1c c\u00f3 \u00fd ngh\u0129a l\u00e2m s\u00e0ng th\u01b0\u1eddng c\u00f3 th\u1ec3 d\u1ef1 \u0111o\u00e1n \u0111\u01b0\u1ee3c v\u00e0 th\u01b0\u1eddng l\u00e0 kh\u00f4ng mong mu\u1ed1n.\u00a0<\/span><\/p>\n<figure id=\"attachment_26284\" aria-describedby=\"caption-attachment-26284\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-26284\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Tuong-tac-thuoc-1-300x200.jpg\" alt=\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c \" width=\"300\" height=\"200\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Tuong-tac-thuoc-1-300x200.jpg 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Tuong-tac-thuoc-1.jpg 424w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-26284\" class=\"wp-caption-text\">T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/figcaption><\/figure>\n<p><span style=\"font-weight: 400;\">T\u01b0\u01a1ng t\u00e1c thu\u1ed1c-thu\u1ed1c \u0111\u01b0\u1ee3c ph\u00e2n lo\u1ea1i th\u00e0nh t\u01b0\u01a1ng t\u00e1c d\u01b0\u1ee3c l\u1ef1c h\u1ecdc v\u00e0 t\u01b0\u01a1ng t\u00e1c d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc. Trong t\u01b0\u01a1ng t\u00e1c d\u01b0\u1ee3c l\u1ef1c h\u1ecdc, m\u1ed9t lo\u1ea1i thu\u1ed1c l\u00e0m thay \u0111\u1ed5i \u0111\u1ed9 nh\u1ea1y c\u1ea3m ho\u1eb7c \u0111\u00e1p \u1ee9ng c\u1ee7a c\u00e1c m\u00f4 \u0111\u1ed1i v\u1edbi m\u1ed9t lo\u1ea1i thu\u1ed1c kh\u00e1c b\u1eb1ng c\u00e1ch c\u00f3 t\u00e1c d\u1ee5ng t\u01b0\u01a1ng t\u1ef1 (ch\u1ee7 v\u1eadn) ho\u1eb7c ng\u0103n ch\u1eb7n (\u0111\u1ed1i kh\u00e1ng). Trong t\u01b0\u01a1ng t\u00e1c d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc, m\u1ed9t lo\u1ea1i thu\u1ed1c th\u01b0\u1eddng l\u00e0m thay \u0111\u1ed5i s\u1ef1 h\u1ea5p thu, ph\u00e2n b\u1ed1, li\u00ean k\u1ebft v\u1edbi protein, chuy\u1ec3n h\u00f3a ho\u1eb7c b\u00e0i ti\u1ebft c\u1ee7a m\u1ed9t lo\u1ea1i thu\u1ed1c kh\u00e1c. Do \u0111\u00f3, s\u1ed1 l\u01b0\u1ee3ng v\u00e0 s\u1ef1 t\u1ed3n t\u1ea1i c\u1ee7a thu\u1ed1c c\u00f3 s\u1eb5n t\u1ea1i c\u00e1c v\u1ecb tr\u00ed th\u1ee5 th\u1ec3 thay \u0111\u1ed5i. C\u00e1c t\u01b0\u01a1ng t\u00e1c d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc l\u00e0m thay \u0111\u1ed5i c\u01b0\u1eddng \u0111\u1ed9 v\u00e0 th\u1eddi gian t\u00e1c d\u1ee5ng ch\u1ee9 kh\u00f4ng ph\u1ea3i lo\u1ea1i t\u00e1c d\u1ee5ng. Ch\u00fang th\u01b0\u1eddng \u0111\u01b0\u1ee3c d\u1ef1 \u0111o\u00e1n d\u1ef1a tr\u00ean ki\u1ebfn \u200b\u200bth\u1ee9c v\u1ec1 t\u1eebng lo\u1ea1i thu\u1ed1c ho\u1eb7c \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n b\u1eb1ng c\u00e1ch theo d\u00f5i n\u1ed3ng \u0111\u1ed9 thu\u1ed1c ho\u1eb7c c\u00e1c d\u1ea5u hi\u1ec7u l\u00e2m s\u00e0ng<\/span><\/p>\n<h2><strong>2.T\u1ed5ng quan v\u1ec1 thu\u1ed1c Naproxen<\/strong><\/h2>\n<h3><span style=\"font-weight: 400;\">2.1 Nh\u00f3m d\u01b0\u1ee3c l\u00fd v\u00e0 ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\"><a href=\"https:\/\/www.vinmec.com\/vi\/thuoc\/naproxen-160\/\">Naproxen<\/a> thu\u1ed9c nh\u00f3m thu\u1ed1c NSAIDs. NSAIDs l\u00e0 m\u1ed9t nh\u00f3m thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i trong \u0111i\u1ec1u tr\u1ecb \u0111au v\u00e0 vi\u00eam. Vi\u1ebft t\u1eaft c\u1ee7a &#8220;Nonsteroidal Anti-Inflammatory Drugs&#8221;, NSAIDs ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf m\u1ed9t lo\u1ea1t c\u00e1c enzym li\u00ean quan \u0111\u1ebfn vi\u1ec7c s\u1ea3n xu\u1ea5t c\u00e1c ch\u1ea5t g\u00e2y vi\u00eam trong c\u01a1 th\u1ec3.\u00a0 Naproxen \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb \u0111au ho\u1eb7c vi\u00eam do c\u00e1c t\u00ecnh tr\u1ea1ng nh\u01b0 vi\u00eam kh\u1edbp, vi\u00eam c\u1ed9t s\u1ed1ng d\u00ednh kh\u1edbp, vi\u00eam g\u00e2n, vi\u00eam bao ho\u1ea1t d\u1ecbch,&#8230;<\/span><\/p>\n<figure id=\"attachment_26285\" aria-describedby=\"caption-attachment-26285\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-26285\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Naproxen-300x300.webp\" alt=\"Naproxen\" width=\"300\" height=\"300\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Naproxen-300x300.webp 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Naproxen-1024x1024.webp 1024w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Naproxen-150x150.webp 150w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Naproxen-768x768.webp 768w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Naproxen.webp 1300w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-26285\" class=\"wp-caption-text\">Naproxen<\/figcaption><\/figure>\n<h3><span style=\"font-weight: 400;\">2.2 C\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Naproxen \u1ee9c ch\u1ebf thu\u1eadn ngh\u1ecbch enzyme cyclooxygenase-1 v\u00e0 2 (COX-1 v\u00e0 2), l\u00e0m gi\u1ea3m h\u00ecnh th\u00e0nh ti\u1ec1n ch\u1ea5t Prostaglandin. Ngo\u00e0i ra, thu\u1ed1c c\u00f2n \u1ee9c ch\u1ebf \u0111i\u1ec1u tr\u1ecb h\u00f3a h\u01b0\u1edbng \u0111\u1ed9ng, thay \u0111\u1ed5i ho\u1ea1t \u0111\u1ed9ng c\u1ee7a t\u1ebf b\u00e0o lympho, \u1ee9c ch\u1ebf s\u1ef1 k\u1ebft t\u1ee5\/k\u00edch ho\u1ea1t b\u1ea1ch c\u1ea7u trung t\u00ednh v\u00e0 gi\u1ea3m m\u1ee9c \u0111\u1ed9 cytokine ti\u1ec1n vi\u00eam.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">2.3 T\u00e1c d\u1ee5ng ph\u1ee5\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 ph\u1ed5 bi\u1ebfn nh\u1ea5t c\u1ee7a Naproxen: nh\u1ea7m l\u1eabn, nh\u1ee9c \u0111\u1ea7u, \u00f9 tai, thay \u0111\u1ed5i th\u1ecb l\u1ef1c, m\u1ec7t m\u1ecfi, bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t v\u00e0 ph\u00e1t ban<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">2.4 Tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Nh\u1eadn tr\u1ee3 gi\u00fap y t\u1ebf kh\u1ea9n c\u1ea5p n\u1ebfu b\u1ecb s\u01b0ng m\u1eb7t ho\u1eb7c c\u1ed5 h\u1ecdng, \u0111au ng\u1ef1c, suy nh\u01b0\u1ee3c, kh\u00f3 th\u1edf, n\u00f3i l\u1eafp ho\u1eb7c c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 th\u1ecb l\u1ef1c ho\u1eb7c th\u0103ng b\u1eb1ng, \u0111au d\u1ea1 d\u00e0y, m\u1ec7t m\u1ecfi ho\u1eb7c suy nh\u01b0\u1ee3c, v\u00e0ng da ho\u1eb7c m\u1eaft, bu\u1ed3n n\u00f4n, n\u00f4n, \u0111i ti\u00eau ra m\u00e1u ho\u1eb7c \u0111en v\u00e0 d\u00ednh, ph\u00e1t ban da, gi\u1ea3m c\u00e2n ho\u1eb7c t\u0103ng c\u00e2n kh\u00f4ng r\u00f5 nguy\u00ean nh\u00e2n, ho\u1eb7c s\u01b0ng tay v\u00e0 b\u00e0n ch\u00e2n<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">2.5 Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Naproxen \u0111\u01b0\u1ee3c ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n sau \u0111\u00e2y: qu\u00e1 m\u1eabn, ti\u1ec1n s\u1eed hen suy\u1ec5n, m\u00e0y \u0111ay ho\u1eb7c c\u00e1c ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng kh\u00e1c sau khi d\u00f9ng Aspirin ho\u1eb7c c\u00e1c NSAID kh\u00e1c, c\u00f3 ti\u1ec1n s\u1eed ph\u1eabu thu\u1eadt b\u1eafc c\u1ea7u \u0111\u1ed9ng m\u1ea1ch v\u00e0nh (CABG), ti\u1ec1n s\u1eed huy\u1ebft kh\u1ed1i tim m\u1ea1ch<\/span><\/p>\n<h2><strong>3.T\u1ed5ng quan v\u1ec1 Ibuprofen<\/strong><\/h2>\n<h3><span style=\"font-weight: 400;\">3.1 Nh\u00f3m d\u01b0\u1ee3c l\u00fd v\u00e0 ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng\u00a0\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Ibuprofen thu\u1ed9c nh\u00f3m thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid (NSAID). Ibuprofen \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 h\u1ea1 s\u1ed1t v\u00e0 \u0111i\u1ec1u tr\u1ecb \u0111au ho\u1eb7c vi\u00eam do nhi\u1ec1u t\u00ecnh tr\u1ea1ng nh\u01b0 \u0111au \u0111\u1ea7u , \u0111au r\u0103ng , \u0111au l\u01b0ng , vi\u00eam kh\u1edbp, chu\u1ed9t r\u00fat kinh nguy\u1ec7t ho\u1eb7c ch\u1ea5n th\u01b0\u01a1ng nh\u1eb9 v\u00e0 \u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh vi\u00eam nhi\u1ec5m v\u00e0 r\u1ed1i lo\u1ea1n d\u1ea1ng th\u1ea5p. Ibuprofen \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em \u00edt nh\u1ea5t 6 th\u00e1ng tu\u1ed5i.<\/span><\/p>\n<figure id=\"attachment_26286\" aria-describedby=\"caption-attachment-26286\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-26286\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Ibuprofen-300x300.webp\" alt=\"Ibuprofen\" width=\"300\" height=\"300\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Ibuprofen-300x300.webp 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Ibuprofen-1024x1024.webp 1024w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Ibuprofen-150x150.webp 150w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Ibuprofen-768x768.webp 768w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Ibuprofen-1536x1536.webp 1536w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Ibuprofen-2048x2048.webp 2048w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-26286\" class=\"wp-caption-text\">Ibuprofen<\/figcaption><\/figure>\n<h3><span style=\"font-weight: 400;\">3.2 C\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">\u1ee8c ch\u1ebf con \u0111\u01b0\u1eddng COX-1 v\u00e0 COX-2 l\u00e0m gi\u1ea3m bi\u1ec3u hi\u1ec7n c\u1ee7a ti\u1ec1n ch\u1ea5t Prostaglandin l\u00e0m gi\u1ea3m m\u1ee9c \u0111\u1ed9 ph\u1ea3n \u1ee9ng c\u1ee7a t\u1ebf b\u00e0o \u0111\u1ed1i v\u1edbi c\u00e1c k\u00edch th\u00edch b\u1ec7nh l\u00fd ho\u1eb7c sinh l\u00fd. Theo c\u01a1 ch\u1ebf n\u00e0y, c\u00e1c NSAID kh\u00f4ng ch\u1ecdn l\u1ecdc nh\u01b0 Ibuprofen c\u00f3 \u0111\u01b0\u1ee3c c\u00e1c \u0111\u1eb7c t\u00ednh gi\u1ea3m \u0111au, h\u1ea1 s\u1ed1t v\u00e0 ch\u1ed1ng vi\u00eam c\u1ee7a ch\u00fang. \u0110\u1ed1i v\u1edbi Ibuprofen, COX-1 b\u1ecb \u1ee9c ch\u1ebf m\u1ea1nh h\u01a1n kho\u1ea3ng 2,5 l\u1ea7n so v\u1edbi COX-2<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">3.3 T\u00e1c d\u1ee5ng ph\u1ee5\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Xu\u1ea5t huy\u1ebft ti\u00eau h\u00f3a l\u00e0 m\u1ed9t t\u00e1c d\u1ee5ng ph\u1ee5 n\u1ed5i ti\u1ebfng c\u1ee7a vi\u1ec7c s\u1eed d\u1ee5ng Ibuprofen v\u00e0 c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn vi\u00eam d\u1ea1 d\u00e0y, lo\u00e9t, xu\u1ea5t huy\u1ebft ho\u1eb7c th\u1ee7ng do khi \u1ee9c ch\u1ebf \u0111\u1ed3ng d\u1ea1ng COX d\u1eabn \u0111\u1ebfn gi\u1ea3m Prostaglandin, \u0111\u00f3ng vai tr\u00f2 trong vi\u1ec7c ti\u1ebft ch\u1ea5t nh\u1ea7y b\u1ea3o v\u1ec7 d\u1ea1 d\u00e0y. Suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn c\u0169ng l\u00e0 m\u1ed9t v\u1ea5n \u0111\u1ec1 \u0111\u00e1ng lo ng\u1ea1i khi s\u1eed d\u1ee5ng Ibuprofen v\u00ec li\u00ean quan \u0111\u1ebfn y\u1ebfu t\u1ed1 m\u1ea5t n\u01b0\u1edbc. Ph\u00e1t ban c\u0169ng c\u00f3 th\u1ec3 l\u00e0 m\u1ed9t ph\u1ea7n c\u1ee7a h\u1ed9i ch\u1ee9ng nghi\u00eam tr\u1ecdng nh\u01b0 s\u1ed1c ph\u1ea3n v\u1ec7 ho\u1eb7c ph\u1ea3n \u1ee9ng thu\u1ed1c v\u1edbi t\u0103ng b\u1ea1ch c\u1ea7u \u00e1i toan v\u00e0 h\u1ed9i ch\u1ee9ng tri\u1ec7u ch\u1ee9ng to\u00e0n th\u00e2n (DRESS).\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">3.4 Tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">M\u1ed9t s\u1ed1 ng\u01b0\u1eddi s\u1ebd g\u1eb7p tri\u1ec7u ch\u1ee9ng khi s\u1eed d\u1ee5ng v\u01b0\u1ee3t qu\u00e1 li\u1ec1u khuy\u1ebfn c\u00e1o bao g\u1ed3m: \u00f9 tai, \u1ee3 n\u00f3ng, bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au b\u1ee5ng, ti\u00eau ch\u1ea3y, ch\u00f3ng m\u1eb7t, ph\u00e1t ban, \u0111\u1ed5 m\u1ed3 h\u00f4i. C\u00e1c tri\u1ec7u ch\u1ee9ng nghi\u00eam tr\u1ecdng h\u01a1n nh\u01b0 th\u1edf kh\u00f3, co gi\u1eadt, h\u1ea1 huy\u1ebft \u00e1p, \u0111au \u0111\u1ea7u d\u1eef d\u1ed9i, h\u00f4n m\u00ea\u00a0<\/span><\/p>\n<h2><strong>4.T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Naproxen v\u00e0 Ibuprofen\u00a0<\/strong><\/h2>\n<h3><span style=\"font-weight: 400;\">4.1 \u0110\u00e1nh gi\u00e1 m\u1ee9c \u0111\u1ed9 t\u01b0\u01a1ng t\u00e1c t\u1eeb nhi\u1ec1u ngu\u1ed3n\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Medscape: Nghi\u00eam tr\u1ecdng\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Drugs bank: Nghi\u00eam tr\u1ecdng<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lexicomp: Nghi\u00eam tr\u1ecdng\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">4.2 C\u01a1 ch\u1ebf v\u00e0 h\u1eadu qu\u1ea3 t\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Naproxen v\u00e0 Ibuprofen\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Ibuprofen v\u00e0 Naproxen \u0111\u1ec1u l\u00e0m t\u0103ng kh\u1ea3 n\u0103ng ch\u1ed1ng \u0111\u00f4ng m\u00e1u v\u00e0 t\u0103ng Kali huy\u1ebft t\u01b0\u01a1ng. S\u1eed d\u1ee5ng Ibuprofen c\u00f9ng v\u1edbi Naproxen th\u01b0\u1eddng kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn kh\u00edch. K\u1ebft h\u1ee3p c\u00e1c lo\u1ea1i thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 t\u00e1c d\u1ee5ng ph\u1ee5 \u1edf \u0111\u01b0\u1eddng ti\u00eau h\u00f3a nh\u01b0 vi\u00eam, ch\u1ea3y m\u00e1u, lo\u00e9t v\u00e0 hi\u1ebfm g\u1eb7p l\u00e0 th\u1ee7ng. Th\u1ee7ng \u0111\u01b0\u1eddng ti\u00eau h\u00f3a l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng c\u00f3 kh\u1ea3 n\u0103ng g\u00e2y t\u1eed vong v\u00e0 l\u00e0 tr\u01b0\u1eddng h\u1ee3p c\u1ea5p c\u1ee9u y t\u1ebf khi l\u1ed7 th\u1ee7ng h\u00ecnh th\u00e0nh xuy\u00ean su\u1ed1t d\u1ea1 d\u00e0y ho\u1eb7c ru\u1ed9t.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">4.3 C\u00e1ch x\u1eed tr\u00ed\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">N\u00f3i chuy\u1ec7n v\u1edbi b\u00e1c s\u0129 v\u1ec1 c\u00e1c thu\u1ed1c \u0111ang s\u1eed d\u1ee5ng \u0111\u1ec3 n\u1ebfu trong tr\u01b0\u1eddng h\u1ee3p nghi\u00eam tr\u1ecdng c\u00f3 th\u1ec3 thay th\u1ebf c\u00e1c li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb kh\u00e1c<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Naproxen v\u00e0 Ibuprofen l\u00e0 hai lo\u1ea1i thu\u1ed1c NSAIDs ph\u1ed5 bi\u1ebfn \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 gi\u1ea3m \u0111au v\u00e0 vi\u00eam trong \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd nh\u01b0 \u0111au \u0111\u1ea7u, \u0111au l\u01b0ng v\u00e0 vi\u00eam kh\u1edbp. Tuy nhi\u00ean, khi \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi, ch\u00fang c\u00f3 th\u1ec3 g\u00e2y ra t\u01b0\u01a1ng t\u00e1c thu\u1ed1c, l\u00e0m t\u0103ng nguy c\u01a1 c\u00e1c t\u00e1c d\u1ee5ng [&hellip;]<\/p>\n","protected":false},"author":54,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[12],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Naproxen v\u00e0 Ibuprofen - Vinmec<\/title>\n<meta name=\"description\" content=\"Naproxen v\u00e0 Ibuprofen \u0111\u1ec1u thu\u1ed9c NSAIDs th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 gi\u1ea3m \u0111au v\u00e0 vi\u00eam D\u00f9 v\u1eady, t\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa 2 thu\u1ed1c g\u00e2y \u1ea3nh h\u01b0\u1edfng\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Naproxen v\u00e0 Ibuprofen - 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