{"id":25789,"date":"2023-04-22T22:42:14","date_gmt":"2023-04-22T15:42:14","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=25789"},"modified":"2023-04-22T22:42:14","modified_gmt":"2023-04-22T15:42:14","slug":"tuong-tac-thuoc-giua-ketorolac-va-naproxen","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/22\/tuong-tac-thuoc-giua-ketorolac-va-naproxen\/","title":{"rendered":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Ketorolac v\u00e0 Naproxen"},"content":{"rendered":"

Ketorolac v\u00e0 Naproxen l\u00e0 hai lo\u1ea1i thu\u1ed1c thu\u1ed9c nh\u00f3m NSAIDs, th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 gi\u1ea3m \u0111au v\u00e0 vi\u00eam trong \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd nh\u01b0 \u0111au \u0111\u1ea7u, \u0111au l\u01b0ng v\u00e0 vi\u00eam kh\u1edbp. Tuy nhi\u00ean, khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi hai lo\u1ea1i thu\u1ed1c n\u00e0y, c\u00f3 th\u1ec3 g\u00e2y ra t\u01b0\u01a1ng t\u00e1c thu\u1ed1c v\u00e0 t\u0103ng nguy c\u01a1 c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nh\u01b0 \u0111au d\u1ea1 d\u00e0y, ch\u1ea3y m\u00e1u ti\u00eau h\u00f3a v\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5 \u0111\u1ed1i v\u1edbi th\u1eadn. \u0110\u1ec3 gi\u1ea3m thi\u1ec3u t\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Ketorolac v\u00e0 Naproxen, c\u00e1c chuy\u00ean gia khuy\u1ebfn c\u00e1o r\u1eb1ng b\u1ec7nh nh\u00e2n n\u00ean tr\u00e1nh s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi hai lo\u1ea1i thu\u1ed1c n\u00e0y. N\u1ebfu c\u1ea7n thi\u1ebft, b\u1ec7nh nh\u00e2n n\u00ean \u0111\u01b0\u1ee3c theo d\u00f5i ch\u1eb7t ch\u1ebd \u0111\u1ec3 ph\u00e1t hi\u1ec7n s\u1edbm c\u00e1c d\u1ea5u hi\u1ec7u c\u1ea3nh b\u00e1o v\u00e0 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u l\u01b0\u1ee3ng thu\u1ed1c ph\u00f9 h\u1ee3p. B\u1ec7nh nh\u00e2n c\u0169ng n\u00ean tham kh\u1ea3o \u00fd ki\u1ebfn c\u1ee7a b\u00e1c s\u0129 ho\u1eb7c nh\u00e0 d\u01b0\u1ee3c tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng b\u1ea5t k\u1ef3 lo\u1ea1i thu\u1ed1c n\u00e0o, \u0111\u1eb7c bi\u1ec7t l\u00e0 khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi c\u00e1c lo\u1ea1i thu\u1ed1c kh\u00e1c.<\/strong><\/p>\n

1.Th\u00f4ng tin v\u1ec1 t\u01b0\u01a1ng t\u00e1c khi s\u1eed d\u1ee5ng thu\u1ed1c<\/strong><\/h2>\n

T\u01b0\u01a1ng t\u00e1c thu\u1ed1c l\u00e0 s\u1ef1 t\u00e1c d\u1ee5ng qua l\u1ea1i l\u1eabn nhau gi\u1eefa thu\u1ed1c n\u00e0y v\u1edbi thu\u1ed1c kh\u00e1c, gi\u1eefa thu\u1ed1c v\u1edbi t\u00ecnh tr\u1ea1ng sinh l\u00fd ho\u1eb7c b\u1ec7nh l\u00fd c\u1ee7a c\u01a1 th\u1ec3. K\u1ebft qu\u1ea3 c\u1ee7a t\u01b0\u01a1ng t\u00e1c thu\u1ed1c l\u00e0m cho thu\u1ed1c t\u0103ng ho\u1eb7c gi\u1ea3m t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb, ho\u1eb7c l\u00e0m ph\u00e1t sinh m\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n g\u00e2y b\u1ea5t l\u1ee3i cho ng\u01b0\u1eddi b\u1ec7nh. Nguy\u00ean nh\u00e2n c\u1ee7a t\u01b0\u01a1ng t\u00e1c thu\u1ed1c l\u00e0 ph\u1ea3n \u1ee9ng gi\u1eefa thu\u1ed1c v\u1edbi thu\u1ed1c, ho\u1eb7c v\u1edbi t\u00ecnh tr\u1ea1ng s\u1ee9c kh\u1ecfe c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh ho\u1eb7c v\u1edbi c\u00e1c lo\u1ea1i th\u1ef1c ph\u1ea9m m\u00e0 ng\u01b0\u1eddi b\u1ec7nh \u0111ang d\u00f9ng. T\u01b0\u01a1ng t\u00e1c c\u00f3 th\u1ec3 x\u1ea3y ra \u1edf b\u1ea5t k\u1ef3 giai \u0111o\u1ea1n n\u00e0o c\u1ee7a qu\u00e1 tr\u00ecnh thu\u1ed1c \u0111i v\u00e0o c\u01a1 th\u1ec3, t\u1eeb khi thu\u1ed1c \u0111\u01b0\u1ee3c h\u1ea5p thu, ph\u00e2n b\u1ed1, chuy\u1ec3n h\u00f3a, t\u00e1c d\u1ee5ng v\u00e0 th\u1ea3i tr\u1eeb ra ngo\u00e0i. Lu\u00f4n n\u00f3i v\u1edbi b\u00e1c s\u0129 ho\u1eb7c d\u01b0\u1ee3c s\u0129 v\u1ec1 c\u00e1c thu\u1ed1c ng\u01b0\u1eddi b\u1ec7nh \u0111ang d\u00f9ng. Ngo\u00e0i ra c\u00e1c lo\u1ea1i th\u1ef1c ph\u1ea9m b\u1ed5 sung, th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng, kho\u00e1ng ch\u1ea5t ho\u1eb7c c\u00e1c lo\u1ea1i thu\u1ed1c \u0111\u00f4ng y, d\u01b0\u1ee3c li\u1ec7u kh\u00e1c c\u0169ng c\u1ea7n ph\u1ea3i \u0111\u01b0\u1ee3c k\u1ec3 ra \u0111\u1ea7y \u0111\u1ee7 khi ng\u01b0\u1eddi b\u1ec7nh th\u0103m kh\u00e1m v\u1edbi b\u00e1c s\u0129.<\/span><\/p>\n

\"T\u01b0\u01a1ng
T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/figcaption><\/figure>\n

Ng\u01b0\u1eddi b\u1ec7nh n\u00ean \u0111\u1ecdc k\u1ef9 h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng, th\u00f4ng tin v\u1ec1 thu\u1ed1c trong \u0111\u00f3 c\u00f3 nh\u1eafc \u0111\u1ebfn c\u00e1c t\u01b0\u01a1ng t\u00e1c c\u00f3 th\u1ec3 x\u1ea3y ra v\u1edbi thu\u1ed1c. Ng\u01b0\u1eddi b\u1ec7nh c\u0169ng c\u1ea7n hi\u1ec3u v\u1ec1 thu\u1ed1c, t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb, c\u00e1ch d\u00f9ng v\u00e0 c\u00e1ch gi\u1ea3m thi\u1ec3u c\u00e1c nguy c\u01a1 t\u01b0\u01a1ng t\u00e1c v\u00e0 t\u00e1c d\u1ee5ng c\u00f3 h\u1ea1i kh\u00e1c khi \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n v\u1ec1 thu\u1ed1c v\u1edbi d\u01b0\u1ee3c s\u0129. Khi c\u00f3 lo ng\u1ea1i ho\u1eb7c kh\u00f4ng hi\u1ec3u r\u00f5 v\u1ec1 thu\u1ed1c, ng\u01b0\u1eddi b\u1ec7nh c\u00f3 th\u1ec3 h\u1ecfi b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb ho\u1eb7c d\u01b0\u1ee3c s\u0129 nh\u1eb1m \u0111\u1ea3m b\u1ea3o an to\u00e0n, hi\u1ec7u qu\u1ea3 khi d\u00f9ng thu\u1ed1c.<\/span><\/p>\n

2.T\u00ecm hi\u1ec3u v\u1ec1 Ketorolac<\/strong><\/h2>\n

2.1 Nh\u00f3m d\u01b0\u1ee3c l\u00fd v\u00e0 ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng<\/h3>\n

Ketorolac<\/a> thu\u1ed9c nh\u00f3m thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid (NSAID). Ketorolac l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb c\u01a1n \u0111au kh\u1edfi ph\u00e1t c\u1ea5p t\u00ednh t\u1eeb trung b\u00ecnh \u0111\u1ebfn n\u1eb7ng. Ketorolac r\u1ea5t linh ho\u1ea1t v\u00ec n\u00f3 c\u00f3 s\u1eb5n \u1edf nhi\u1ec1u d\u1ea1ng: u\u1ed1ng, x\u1ecbt m\u0169i, IV ho\u1eb7c IM v\u00e0 th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng sau ph\u1eabu thu\u1eadt \u0111\u1ec3 ki\u1ec3m so\u00e1t c\u01a1n \u0111au. Khi k\u1ebft h\u1ee3p v\u1edbi opioid, Ketorolac l\u00e0m gi\u1ea3m \u0111\u00e1ng k\u1ec3 nhu c\u1ea7u opioid v\u00e0 gi\u1ea3m t\u1ef7 l\u1ec7 t\u00e1c d\u1ee5ng ph\u1ee5 nh\u01b0 n\u00f4n m\u1eeda v\u00e0 gi\u1ea3m nhu \u0111\u1ed9ng ru\u1ed9t. \u1ede tr\u1ebb em, Ketorolac c\u00f3 hi\u1ec7u qu\u1ea3 t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi thu\u1ed1c gi\u1ea3m \u0111au nh\u00f3m opioid ch\u00ednh. Trong khoa c\u1ea5p c\u1ee9u, n\u00f3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb th\u00e0nh c\u00f4ng ch\u1ee9ng \u0111au c\u01a1 x\u01b0\u01a1ng, ch\u1ee9ng \u0111au n\u1eeda \u0111\u1ea7u v\u00e0 b\u1ec7nh h\u1ed3ng c\u1ea7u h\u00ecnh li\u1ec1m<\/span><\/p>\n

\"Ketorolac\"
Ketorolac<\/figcaption><\/figure>\n

2.2 C\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng<\/span><\/h3>\n

C\u01a1 ch\u1ebf ch\u00ednh x\u00e1c c\u1ee7a Ketorolac v\u1eabn ch\u01b0a \u0111\u01b0\u1ee3c bi\u1ebft. Ketorolac, gi\u1ed1ng nh\u01b0 c\u00e1c NSAID kh\u00e1c, ng\u0103n ch\u1eb7n cyclooxygenase (COX), l\u00e0 nh\u1eefng enzym chuy\u1ec3n Acid arachidonic th\u00e0nh Prostaglandin, Prostacyclin v\u00e0 Thromboxane. S\u1ef1 \u1ee9c ch\u1ebf c\u00e1c ch\u1ea5t n\u00e0y l\u00e0m gi\u1ea3m \u0111au, s\u1ed1t v\u00e0 vi\u00eam. Ketorolac l\u00e0m nh\u01b0 v\u1eady b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf c\u1ea3 cyclooxygenase-1 v\u00e0 cyclooxygenase-2 v\u1edbi hi\u1ec7u l\u1ef1c \u0111\u01b0\u1ee3c ch\u1ee9ng minh cao h\u01a1n h\u1ea7u h\u1ebft c\u00e1c NSAID kh\u00e1c<\/span><\/p>\n

2.3 T\u00e1c d\u1ee5ng ph\u1ee5\u00a0<\/span><\/h3>\n

T\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a Ketorolac t\u0103ng \u0111\u00e1ng k\u1ec3 khi s\u1eed d\u1ee5ng v\u1edbi li\u1ec1u l\u01b0\u1ee3ng cao h\u01a1n, trong th\u1eddi gian h\u01a1n n\u0103m ng\u00e0y v\u00e0 \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n tr\u00ean 75 tu\u1ed5i. Gi\u1ed1ng nh\u01b0 c\u00e1c NSAID kh\u00e1c, Ketorolac cho th\u1ea5y m\u1ed1i t\u01b0\u01a1ng quan v\u1edbi c\u00e1c nguy c\u01a1 \u0111\u00e1ng k\u1ec3 v\u1ec1 \u0111\u01b0\u1eddng ti\u00eau h\u00f3a (GI), th\u1eadn v\u00e0 tim m\u1ea1ch. Trong h\u1ec7 ti\u00eau h\u00f3a, n\u00f3 c\u00f3 th\u1ec3 g\u00e2y lo\u00e9t d\u1ea1 d\u00e0y v\u00e0\/ho\u1eb7c th\u1ee7ng d\u1ea1 d\u00e0y ho\u1eb7c ru\u1ed9t. Ketorolac c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 bi\u1ebfn c\u1ed1 huy\u1ebft kh\u1ed1i tim m\u1ea1ch, nh\u1ed3i m\u00e1u c\u01a1 tim v\u00e0 \u0111\u1ed9t qu\u1ef5 xu\u1ea5t huy\u1ebft. Suy tim l\u00e0 m\u1ed9t y\u1ebfu t\u1ed1 r\u1ee7i ro \u0111\u00e1ng k\u1ec3 \u0111\u1ed1i v\u1edbi t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a NSAID<\/span><\/p>\n

2.4 Tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u\u00a0<\/span><\/h3>\n

S\u1eed d\u1ee5ng Ketorolac v\u1edbi li\u1ec1u l\u01b0\u1ee3ng cao ho\u1eb7c k\u00e9o d\u00e0i c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn nhi\u1ec5m \u0111\u1ed9c gan v\u00e0 th\u1eadn. Ngo\u00e0i ra, Ketorolac c\u00f3 th\u1ec3 g\u00e2y ra nhi\u1ec1u v\u1ea5n \u0111\u1ec1 v\u1ec1 da, ch\u1eb3ng h\u1ea1n nh\u01b0 ho\u1ea1i t\u1eed bi\u1ec3u b\u00ec nhi\u1ec5m \u0111\u1ed9c. Khi k\u1ebft h\u1ee3p v\u1edbi Lithium, n\u00f3 l\u00e0m t\u0103ng nguy c\u01a1 ng\u1ed9 \u0111\u1ed9c Lithium, do Lithium c\u0169ng \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua th\u1eadn<\/span><\/p>\n

2.5 Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh<\/span><\/h3>\n

Ketorolac ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf nh\u1eefng ng\u01b0\u1eddi c\u00f3 ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i ho\u1eb7c d\u1ecb \u1ee9ng v\u1edbi NSAID. Kh\u00f4ng n\u00ean d\u00f9ng trong ph\u1eabu thu\u1eadt ho\u1eb7c tr\u01b0\u1edbc ph\u1eabu thu\u1eadt do t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u. N\u00f3 kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn kh\u00edch trong qu\u00e1 tr\u00ecnh chuy\u1ec3n d\u1ea1 v\u00e0 sinh n\u1edf, v\u00ec n\u00f3 \u1ea3nh h\u01b0\u1edfng ti\u00eau c\u1ef1c \u0111\u1ebfn tu\u1ea7n ho\u00e0n c\u1ee7a thai nhi v\u00e0 gi\u1ea3m co b\u00f3p t\u1eed cung. Ketorolac ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh th\u1eadn ho\u1eb7c suy th\u1eadn v\u00ec n\u00f3 c\u00f3 th\u1ec3 l\u00e0m t\u0103ng kh\u1ea3 n\u0103ng gi\u1eef n\u01b0\u1edbc v\u00e0 l\u00e0m suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn. Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh li\u00ean quan \u0111\u1ebfn \u0111\u01b0\u1eddng ti\u00eau h\u00f3a bao g\u1ed3m b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng \u0111ang ho\u1ea1t \u0111\u1ed9ng, ch\u1ea3y m\u00e1u \u0111\u01b0\u1eddng ti\u00eau h\u00f3a g\u1ea7n \u0111\u00e2y ho\u1eb7c th\u1ee7ng \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. C\u1ea7n h\u1ebft s\u1ee9c th\u1eadn tr\u1ecdng khi d\u00f9ng cho ng\u01b0\u1eddi cao tu\u1ed5i<\/span><\/p>\n

3.T\u00ecm hi\u1ec3u v\u1ec1 Naproxen<\/strong><\/h2>\n

3.1 Nh\u00f3m d\u01b0\u1ee3c l\u00fd v\u00e0 ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng\u00a0<\/span><\/h3>\n

Naproxen thu\u1ed9c nh\u00f3m thu\u1ed1c NSAIDs. NSAIDs l\u00e0 m\u1ed9t nh\u00f3m thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i trong \u0111i\u1ec1u tr\u1ecb \u0111au v\u00e0 vi\u00eam. Vi\u1ebft t\u1eaft c\u1ee7a “Nonsteroidal Anti-Inflammatory Drugs”, NSAIDs ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf m\u1ed9t lo\u1ea1t c\u00e1c enzym li\u00ean quan \u0111\u1ebfn vi\u1ec7c s\u1ea3n xu\u1ea5t c\u00e1c ch\u1ea5t g\u00e2y vi\u00eam trong c\u01a1 th\u1ec3.\u00a0 Naproxen \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb \u0111au ho\u1eb7c vi\u00eam do c\u00e1c t\u00ecnh tr\u1ea1ng nh\u01b0 vi\u00eam kh\u1edbp, vi\u00eam c\u1ed9t s\u1ed1ng d\u00ednh kh\u1edbp, vi\u00eam g\u00e2n, vi\u00eam bao ho\u1ea1t d\u1ecbch,…<\/span><\/p>\n

\"Naproxen\"
Naproxen<\/figcaption><\/figure>\n

3.2 C\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng<\/span><\/h3>\n

Naproxen \u1ee9c ch\u1ebf thu\u1eadn ngh\u1ecbch enzyme cyclooxygenase-1 v\u00e0 2 (COX-1 v\u00e0 2), l\u00e0m gi\u1ea3m h\u00ecnh th\u00e0nh ti\u1ec1n ch\u1ea5t Prostaglandin. Ngo\u00e0i ra, thu\u1ed1c c\u00f2n \u1ee9c ch\u1ebf \u0111i\u1ec1u tr\u1ecb h\u00f3a h\u01b0\u1edbng \u0111\u1ed9ng, thay \u0111\u1ed5i ho\u1ea1t \u0111\u1ed9ng c\u1ee7a t\u1ebf b\u00e0o lympho, \u1ee9c ch\u1ebf s\u1ef1 k\u1ebft t\u1ee5\/k\u00edch ho\u1ea1t b\u1ea1ch c\u1ea7u trung t\u00ednh v\u00e0 gi\u1ea3m m\u1ee9c \u0111\u1ed9 cytokine ti\u1ec1n vi\u00eam.<\/span><\/p>\n

3.3 T\u00e1c d\u1ee5ng ph\u1ee5\u00a0<\/span><\/h3>\n

C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 ph\u1ed5 bi\u1ebfn nh\u1ea5t c\u1ee7a Naproxen: nh\u1ea7m l\u1eabn, nh\u1ee9c \u0111\u1ea7u, \u00f9 tai, thay \u0111\u1ed5i th\u1ecb l\u1ef1c, m\u1ec7t m\u1ecfi, bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t v\u00e0 ph\u00e1t ban<\/span><\/p>\n

3.4 Tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u\u00a0<\/span><\/h3>\n

Nh\u1eadn tr\u1ee3 gi\u00fap y t\u1ebf kh\u1ea9n c\u1ea5p n\u1ebfu b\u1ecb s\u01b0ng m\u1eb7t ho\u1eb7c c\u1ed5 h\u1ecdng, \u0111au ng\u1ef1c, suy nh\u01b0\u1ee3c, kh\u00f3 th\u1edf, n\u00f3i l\u1eafp ho\u1eb7c c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 th\u1ecb l\u1ef1c ho\u1eb7c th\u0103ng b\u1eb1ng, \u0111au d\u1ea1 d\u00e0y, m\u1ec7t m\u1ecfi ho\u1eb7c suy nh\u01b0\u1ee3c, v\u00e0ng da ho\u1eb7c m\u1eaft, bu\u1ed3n n\u00f4n, n\u00f4n, \u0111i ti\u00eau ra m\u00e1u ho\u1eb7c \u0111en v\u00e0 d\u00ednh, ph\u00e1t ban da, gi\u1ea3m c\u00e2n ho\u1eb7c t\u0103ng c\u00e2n kh\u00f4ng r\u00f5 nguy\u00ean nh\u00e2n, ho\u1eb7c s\u01b0ng tay v\u00e0 b\u00e0n ch\u00e2n<\/span><\/p>\n

3.5 Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh\u00a0<\/span><\/h3>\n

Naproxen \u0111\u01b0\u1ee3c ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n sau \u0111\u00e2y: qu\u00e1 m\u1eabn, ti\u1ec1n s\u1eed hen suy\u1ec5n, m\u00e0y \u0111ay ho\u1eb7c c\u00e1c ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng kh\u00e1c sau khi d\u00f9ng aspirin ho\u1eb7c c\u00e1c NSAID kh\u00e1c, c\u00f3 ti\u1ec1n s\u1eed ph\u1eabu thu\u1eadt b\u1eafc c\u1ea7u \u0111\u1ed9ng m\u1ea1ch v\u00e0nh (CABG), ti\u1ec1n s\u1eed huy\u1ebft kh\u1ed1i tim m\u1ea1ch<\/span><\/p>\n

4.T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Ketorolac v\u00e0 Naproxen<\/strong><\/h2>\n

4.1 \u0110\u00e1nh gi\u00e1 m\u1ee9c \u0111\u1ed9 t\u01b0\u01a1ng t\u00e1c t\u1eeb nhi\u1ec1u ngu\u1ed3n\u00a0<\/span><\/h3>\n

Medscape: Nghi\u00eam tr\u1ecdng\u00a0<\/span><\/p>\n

Drugs bank: Nghi\u00eam tr\u1ecdng\u00a0<\/span><\/p>\n

Lexicomp: V\u1eeba ph\u1ea3i\u00a0<\/span><\/p>\n

4.2 C\u01a1 ch\u1ebf v\u00e0 h\u1eadu qu\u1ea3 t\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Ketorolac v\u00e0 Naproxen<\/span><\/h3>\n

Ketorolac v\u00e0 Naproxen \u0111\u1ec1u l\u00e0m t\u0103ng kh\u1ea3 n\u0103ng ch\u1ed1ng \u0111\u00f4ng m\u00e1u, t\u0103ng Kali huy\u1ebft t\u01b0\u01a1ng v\u00e0 l\u00e0m t\u0103ng \u0111\u1ed9c t\u00ednh c\u1ee7a lo\u1ea1i kia b\u1eb1ng hi\u1ec7p \u0111\u1ed3ng d\u01b0\u1ee3c l\u1ef1c h\u1ecdc<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Ketorolac v\u00e0 Naproxen l\u00e0 hai lo\u1ea1i thu\u1ed1c thu\u1ed9c nh\u00f3m NSAIDs, th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 gi\u1ea3m \u0111au v\u00e0 vi\u00eam trong \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd nh\u01b0 \u0111au \u0111\u1ea7u, \u0111au l\u01b0ng v\u00e0 vi\u00eam kh\u1edbp. Tuy nhi\u00ean, khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi hai lo\u1ea1i thu\u1ed1c n\u00e0y, c\u00f3 th\u1ec3 g\u00e2y ra t\u01b0\u01a1ng t\u00e1c thu\u1ed1c v\u00e0 t\u0103ng nguy c\u01a1 […]<\/p>\n","protected":false},"author":54,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[12],"tags":[],"yoast_head":"\nT\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Ketorolac v\u00e0 Naproxen - Vinmec<\/title>\n<meta name=\"description\" content=\"M\u1eb7c d\u00f9 Ketorolac v\u00e0 Naproxen \u0111\u1ec1u \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong gi\u1ea3m \u0111au kh\u00e1ng vi\u00eam nh\u01b0ng t\u01b0\u01a1ng t\u00e1c thu\u1ed1c v\u1eabn c\u1ea7n \u0111\u01b0\u1ee3c ch\u00fa \u00fd v\u00ec \u1ea3nh h\u01b0\u1edfng s\u1ee9c kh\u1ecfe\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Ketorolac v\u00e0 Naproxen - 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