{"id":25403,"date":"2023-04-22T22:10:07","date_gmt":"2023-04-22T15:10:07","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=25403"},"modified":"2023-04-22T22:10:07","modified_gmt":"2023-04-22T15:10:07","slug":"tuong-tac-thuoc-giua-fluoxetin-va-tramadol","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/22\/tuong-tac-thuoc-giua-fluoxetin-va-tramadol\/","title":{"rendered":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Fluoxetin v\u00e0 Tramadol"},"content":{"rendered":"<p><strong>Fluoxetin v\u00e0 Tramadol l\u00e0 hai lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng ph\u1ed5 bi\u1ebfn trong \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd li\u00ean quan \u0111\u1ebfn r\u1ed1i lo\u1ea1n t\u00e2m l\u00fd v\u00e0 \u0111au. Tuy nhi\u00ean, khi k\u1ebft h\u1ee3p s\u1eed d\u1ee5ng hai lo\u1ea1i thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 g\u00e2y ra t\u01b0\u01a1ng t\u00e1c, t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb v\u00e0 t\u0103ng nguy c\u01a1 g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 cho b\u1ec7nh nh\u00e2n. Hi\u1ec3u r\u00f5 v\u1ec1 t\u01b0\u01a1ng t\u00e1c gi\u1eefa Fluoxetin v\u00e0 Tramadol l\u00e0 r\u1ea5t quan tr\u1ecdng \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 trong \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd n\u00e0y.<\/strong><\/p>\n<h2><strong>1. Th\u00f4ng tin chung v\u1ec1 thu\u1ed1c Fluoxetin<\/strong><\/h2>\n<h3><strong>1.1 C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/strong><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fluoxetin l\u00e0 m\u1ed9t thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m hai v\u00f2ng c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc thu h\u1ed3i Serotonin t\u1ea1i tr\u01b0\u1edbc synap c\u1ee7a c\u00e1c t\u1ebf b\u00e0o th\u1ea7n kinh serotoninergic, l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 serotonin \u0111\u1ebfn sau synap, t\u1eeb \u0111\u00f3 c\u1ea3i thi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng tr\u1ea7m c\u1ea3m \u01a1\u0309 b\u1ec7nh nh\u00e2n tr\u1ea7m c\u1ea3m. Ch\u1ea5t chuy\u1ec3n h\u00f3a ch\u00ednh c\u1ee7a Fluoxetin l\u00e0 Norfluoxetin c\u0169ng c\u00f3 t\u00e1c d\u1ee5ng t\u01b0\u01a1ng t\u1ef1 nh\u01b0 Fluoxetin, do \u0111\u00f3 hi\u1ec7u qu\u1ea3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 serotonin r\u1ea5t m\u1ea1nh. Tuy Fluoxetin c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m t\u0103ng nhanh n\u1ed3ng \u0111\u1ed9 serotonin t\u1ea1i khe synap serotoninergic c\u1ee7a t\u1ebf b\u00e0o th\u1ea7n kinh nh\u01b0ng hi\u1ec7u qu\u1ea3 c\u1ea3i thi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng v\u1ec1 tr\u1ea7m c\u1ea3m tr\u00ean b\u1ec7nh nh\u00e2n l\u1ea1i r\u1ea5t ch\u1eadm, th\u01b0\u1eddng ph\u1ea3i t\u1eeb 3 \u2013 5 tu\u1ea7n, do v\u1eady tr\u01b0\u1eddng h\u1ee3p tr\u1ea7m c\u1ea3m n\u1eb7ng kh\u00f4ng th\u1ec3 thuy\u00ean gi\u1ea3m ngay khi d\u00f9ng thu\u1ed1c n\u00e0y.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kh\u00f4ng gi\u1ed1ng nh\u01b0 c\u00e1c thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m 3 v\u00f2ng c\u0169 ho\u1eb7c m\u1ed9t v\u00e0i thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m kh\u00e1c, v\u1edbi li\u1ec1u \u0111i\u1ec1u tr\u1ecb Fluoxetin ch\u1ec9 c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc tr\u00ean k\u00eanh thu h\u1ed3i serotonin m\u00e0 \u00edt c\u00f3 t\u00e1c d\u1ee5ng tr\u00ean c\u00e1c th\u1ee5 th\u1ec3 kh\u00e1c nh\u01b0 kh\u00e1ng cholinergic, ch\u1eb9n \u03b11-adrenergic ho\u1eb7c kh\u00e1ng histamin. V\u00ec v\u1eady, nguy c\u01a1 t\u00e1c d\u1ee5ng ph\u1ee5 do kh\u00e1ng cholinergic (kh\u00f4 mi\u1ec7ng, m\u1edd m\u1eaft, b\u00ed ti\u1ec3u, t\u00e1o b\u00f3n), ch\u1eb9n \u03b11-adrenergic (h\u1ea1 huy\u1ebft \u00e1p t\u01b0 th\u1ebf \u0111\u1ee9ng) ho\u1eb7c kh\u00e1ng histamin (bu\u1ed3n ng\u1ee7) \u00edt g\u1eb7p khi s\u1eed d\u1ee5ng \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Fluoxetin.<\/span><\/li>\n<\/ul>\n<figure id=\"attachment_25607\" aria-describedby=\"caption-attachment-25607\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-25607\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Fluoxetine-300x199.png\" alt=\"Fluoxetine\" width=\"300\" height=\"199\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Fluoxetine-300x199.png 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Fluoxetine-768x510.png 768w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Fluoxetine.png 1000w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-25607\" class=\"wp-caption-text\">Fluoxetin<\/figcaption><\/figure>\n<h3><strong>1.2 Ch\u1ec9 \u0111\u1ecbnh<\/strong><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">B\u1ec7nh tr\u1ea7m c\u1ea3m, h\u1ed9i ch\u1ee9ng ho\u1ea3ng s\u1ee3, ch\u1ee9ng \u0103n v\u00f4 \u0111\u1ed9, r\u1ed1i lo\u1ea1n xung l\u1ef1c c\u01b0\u01a1\u0303ng b\u1ee9c \u2013 \u00e1m \u1ea3nh.<\/span><\/li>\n<\/ul>\n<h3><strong>1.3 T\u00e1c d\u1ee5ng ph\u1ee5<\/strong><\/h3>\n<p><b><i>Th\u01b0\u1eddng g\u1eb7p:<\/i><\/b><span style=\"font-weight: 400;\"> M\u1ec7t m\u1ecfi, ch\u00f3ng m\u1eb7t, ra m\u1ed3 h\u00f4i, li\u1ec7t d\u01b0\u01a1ng, kh\u00f4ng c\u00f3 kh\u1ea3 n\u0103ng xu\u1ea5t tinh, gi\u1ea3m t\u00ecnh d\u1ee5c, bu\u1ed3n n\u00f4n, \u1ec9a ch\u1ea3y, ch\u00e1n \u0103n, ph\u00e1t ban, ng\u1ee9a, run, b\u1ed3n ch\u1ed3n, m\u1ea5t ng\u1ee7, lo s\u1ee3.<\/span><\/p>\n<p><b><i>\u00cdt g\u1eb7p:<\/i><\/b><span style=\"font-weight: 400;\"> Nh\u1ee9c \u0111\u1ea7u, n\u00f4n, r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a, kh\u00f4 mi\u1ec7ng, m\u00e0y \u0111ay, co tho\u1eaft ph\u1ebf qu\u1ea3n, b\u00ed ti\u1ec3u ti\u1ec7n,<\/span><\/p>\n<p><b><i>Hi\u1ebfm g\u1eb7p:<\/i><\/b><span style=\"font-weight: 400;\"> Lo\u1ea1n nh\u1ecbp tim, m\u1ea1ch nhanh, vi\u00eam m\u1ea1ch, ph\u1ea3n \u1ee9ng ngo\u1ea1i th\u00e1p, r\u1ed1i lo\u1ea1n v\u1eadn \u0111\u1ed9ng, h\u1ed9i ch\u1ee9ng Parkinson, d\u1ecb c\u1ea3m, \u0111\u1ed9ng kinh, h\u1ed9i ch\u1ee9ng serotonin, x\u01a1 h\u00f3a ph\u00f4\u0309i, ph\u00f9 thanh qu\u1ea3n,..<\/span><\/p>\n<h2><strong>2. Th\u00f4ng tin chung v\u1ec1 thu\u1ed1c <a href=\"https:\/\/www.vinmec.com\/vi\/thong-tin-duoc\/su-dung-thuoc-toan\/cong-dung-thuoc-tramadol\/\">Tramadol<\/a><\/strong><\/h2>\n<h3><strong>2.1 C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/strong><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tramadol l\u00e0 m\u1ed9t thu\u1ed1c gi\u1ea3m \u0111au t\u1ed5ng h\u1ee3p c\u00f3 t\u00e1c \u0111\u1ed9ng trung t\u00e2m. Thu\u1ed1c (v\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh M1) c\u00f3 t\u00e1c d\u1ee5ng gi\u1ed1ng thu\u1ed1c phi\u1ec7n, do c\u00f3 ho\u1ea1t t\u00ednh ch\u1ecdn l\u1ecdc tr\u00ean c\u00e1c th\u1ee5 th\u1ec3 \u00b5. Ngo\u00e0i ho\u1ea1t t\u00ednh gi\u1ed1ng thu\u1ed1c phi\u1ec7n, Tramadol c\u00f2n \u1ee9c ch\u1ebf s\u1ef1 t\u00e1i h\u1ea5p thu m\u1ed9t s\u1ed1 monoamin (norepinephrin, serotonin), \u0111i\u1ec1u n\u00e0y g\u00f3p ph\u1ea7n v\u00e0o t\u00e1c d\u1ee5ng gi\u1ea3m \u0111au c\u1ee7a thu\u1ed1c. Trong th\u1ef1c nghi\u1ec7m tr\u00ean \u0111\u1ed9ng v\u1eadt, ch\u1ea5t chuy\u1ec3n h\u00f3a M1 c\u00f3 t\u00e1c d\u1ee5ng gi\u1ea3m \u0111au m\u1ea1nh g\u1ea5p 6 l\u1ea7n v\u00e0 g\u1eafn v\u1edbi th\u1ee5 th\u1ec3 \u00b5 m\u1ea1nh g\u1ea5p 200 l\u1ea7n so v\u1edbi thu\u1ed1c g\u1ed1c. T\u00e1c d\u1ee5ng gi\u1ea3m \u0111au c\u1ee7a Tramadol ch\u1ec9 b\u1ecb \u0111\u1ed1i kh\u00e1ng m\u1ed9t ph\u1ea7n b\u1edfi Naloxon \u1edf ng\u01b0\u1eddi kh\u1ecfe m\u1ea1nh.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tramadol c\u0169ng c\u00f3 th\u1ec3 g\u00e2y nghi\u1ec7n, nh\u01b0ng kh\u1ea3 n\u0103ng g\u00e2y nghi\u1ec7n th\u1ea5p. Tramadol c\u0169ng c\u00f3 nhi\u1ec1u t\u00e1c d\u1ee5ng d\u01b0\u1ee3c l\u00fd v\u00e0 ADR gi\u1ed1ng thu\u1ed1c phi\u1ec7n. T\u00e1c d\u1ee5ng g\u00e2y suy gi\u1ea3m h\u00f4 h\u1ea5p c\u1ee7a thu\u1ed1c y\u1ebfu h\u01a1n so v\u1edbi Morphine v\u00e0 th\u01b0\u1eddng kh\u00f4ng quan tr\u1ecdng v\u1ec1 m\u1eb7t l\u00e2m s\u00e0ng v\u1edbi c\u00e1c li\u1ec1u th\u01b0\u1eddng d\u00f9ng.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">V\u1edbi li\u1ec1u t\u01b0\u01a1ng \u0111\u1ed1i cao (nh\u01b0 c\u00e1c li\u1ec1u d\u00f9ng ngo\u00e0i \u0111\u01b0\u1eddng ti\u00eau h\u00f3a), Tramadol c\u00f3 th\u1ec3 g\u00e2y suy gi\u1ea3m h\u00f4 h\u1ea5p, do \u0111\u00f3 ph\u1ea3i d\u00f9ng th\u1eadn tr\u1ecdng, ngay c\u1ea3 c\u00e1c li\u1ec1u u\u1ed1ng th\u00f4ng th\u01b0\u1eddng, \u0111\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 suy gi\u1ea3m h\u00f4 h\u1ea5p. V\u1edbi li\u1ec1u u\u1ed1ng th\u00f4ng th\u01b0\u1eddng, thu\u1ed1c c\u00f3 \u00edt t\u00e1c d\u1ee5ng v\u1ec1 tim m\u1ea1ch, m\u1eb7c d\u00f9 \u0111\u00f4i khi c\u00f3 th\u1ec3 x\u1ea3y ra h\u1ea1 huy\u1ebft \u00e1p, ng\u1ea5t, v\u00e0 nh\u1ecbp tim nhanh.<\/span><\/li>\n<\/ul>\n<figure id=\"attachment_25608\" aria-describedby=\"caption-attachment-25608\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-25608\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Tramadol-300x225.jpg\" alt=\"Tramadol\" width=\"300\" height=\"225\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Tramadol-300x225.jpg 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Tramadol-1024x768.jpg 1024w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Tramadol-768x576.jpg 768w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Tramadol.jpg 1200w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-25608\" class=\"wp-caption-text\">Tramadol<\/figcaption><\/figure>\n<h3><strong>2.2 Ch\u1ec9 \u0111\u1ecbnh<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">Tramadol \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb \u0111au v\u1eeba v\u00e0 \u0111au n\u1eb7ng.<\/span><\/p>\n<h3><strong>2.3 T\u00e1c d\u1ee5ng ph\u1ee5<\/strong><\/h3>\n<p><b><i>Th\u01b0\u1eddng g\u1eb7p:<\/i><\/b><span style=\"font-weight: 400;\"> Vi\u00eam ph\u1ebf qu\u1ea3n, ho, kh\u00f3 th\u1edf, vi\u00eam m\u0169i h\u1ecdng, vi\u00eam xoang, \u0111au h\u1ecdng, nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p tr\u00ean, t\u00e1o b\u00f3n, bu\u1ed3n n\u00f4n, n\u00f4n, kh\u00f3 ti\u00eau, ti\u00eau ch\u1ea3y, kh\u00f4 mi\u1ec7ng, ch\u00e1n \u0103n, t\u0103ng ngon mi\u1ec7ng, gi\u1ea3m c\u00e2n, \u0111\u1ea7y h\u01a1i, \u0111au \u0111\u1ea7u, ng\u1ee7 g\u00e0, m\u1ea5t ng\u1ee7, t\u00ecnh tr\u1ea1ng k\u00edch \u0111\u1ed9ng, lo l\u1eafng, l\u00fa l\u1eabn, suy gi\u1ea3m ph\u1ed1i h\u1ee3p, m\u1ea5t nh\u00e2n c\u00e1ch, \u0111\u1ecf b\u1eebng, h\u1ea1 huy\u1ebft \u00e1p t\u01b0 th\u1ebf, \u0111au ng\u1ef1c, t\u0103ng huy\u1ebft \u00e1p, ph\u00f9 ngo\u1ea1i bi\u00ean, gi\u00e3n m\u1ea1ch,\u00a0<\/span><\/p>\n<p><b><i>\u00cdt g\u1eb7p:<\/i><\/b><span style=\"font-weight: 400;\"> Co th\u1eaft ph\u1ebf qu\u1ea3n, vi\u00eam ph\u1ed5i, ph\u00f9 ph\u1ed5i. H\u1ed9i ch\u1ee9ng cai thu\u1ed1c c\u00f3 th\u1ec3 g\u1ed3m lo l\u1eafng, ti\u00eau ch\u1ea3y, \u1ea3o gi\u00e1c, bu\u1ed3n n\u00f4n, \u0111au, d\u1ef1ng l\u00f4ng, r\u00e9t run, to\u00e1t m\u1ed3 h\u00f4i, v\u00e0 run. C\u00e1c tri\u1ec7u ch\u1ee9ng ng\u1eebng thu\u1ed1c \u00edt g\u1eb7p c\u00f3 th\u1ec3 g\u1ed3m lo l\u1eafng nghi\u00eam tr\u1ecdng, c\u01a1n ho\u1ea3ng s\u1ee3, ho\u1eb7c d\u1ecb c\u1ea3m. Ph\u00f9 m\u1ea1ch, nh\u1ecbp tim ch\u1eadm,&#8230;<\/span><\/p>\n<h2><strong>3. T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Fluoxetin v\u00e0 Tramadol<\/strong><\/h2>\n<h3><strong>3.1 C\u01a1 ch\u1ebf<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">Vi\u1ec7c s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi Tramadol v\u1edbi c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf t\u00e1i h\u1ea5p thu Serotonin c\u00f3 ch\u1ecdn l\u1ecdc (SSRI) c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 m\u1eafc h\u1ed9i ch\u1ee9ng Serotonin, m\u1ed9t t\u00ecnh tr\u1ea1ng hi\u1ebfm g\u1eb7p nh\u01b0ng nghi\u00eam tr\u1ecdng v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng g\u00e2y t\u1eed vong \u0111\u01b0\u1ee3c cho l\u00e0 do qu\u00e1 k\u00edch th\u00edch qu\u00e1 m\u1ee9c c\u00e1c th\u1ee5 th\u1ec3 5-HT1A v\u00e0 2A tr\u00ean th\u00e2n n\u00e3o.<\/span><\/p>\n<h3><strong>3.2 T\u00e1c d\u1ee5ng ph\u1ee5 c\u00f3 th\u1ec3 x\u1ea3y ra khi s\u1eed d\u1ee5ng Fluoxetin v\u00e0 Tramadol c\u00f9ng nhau<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">C\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a h\u1ed9i ch\u1ee9ng Serotonin:\u00a0<\/span><\/p>\n<ul>\n<li><span style=\"font-weight: 400;\">Thay \u0111\u1ed5i tr\u1ea1ng th\u00e1i tinh th\u1ea7n nh\u01b0 kh\u00f3 ch\u1ecbu, thay \u0111\u1ed5i \u00fd th\u1ee9c, l\u00fa l\u1eabn, \u1ea3o gi\u00e1c v\u00e0 h\u00f4n m\u00ea<\/span><\/li>\n<li><span style=\"font-weight: 400;\">R\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng t\u1ef1 ch\u1ee7 nh\u01b0 nh\u1ecbp tim nhanh, t\u0103ng th\u00e2n nhi\u1ec7t, to\u00e1t m\u1ed3 h\u00f4i, run r\u1ea9y, huy\u1ebft \u00e1p kh\u00f4ng \u1ed5n \u0111\u1ecbnh v\u00e0 gi\u00e3n \u0111\u1ed3ng t\u1eed<\/span><\/li>\n<li><span style=\"font-weight: 400;\">C\u00e1c b\u1ea5t th\u01b0\u1eddng v\u1ec1 th\u1ea7n kinh c\u01a1 nh\u01b0 t\u0103ng ph\u1ea3n x\u1ea1, gi\u1eadt c\u01a1, run, c\u1ee9ng v\u00e0 m\u1ea5t \u0111i\u1ec1u h\u00f2a<\/span><\/li>\n<li><span style=\"font-weight: 400;\">C\u00e1c tri\u1ec7u ch\u1ee9ng ti\u00eau h\u00f3a nh\u01b0 \u0111au qu\u1eb7n b\u1ee5ng, bu\u1ed3n n\u00f4n, n\u00f4n v\u00e0 ti\u00eau ch\u1ea3y<\/span><\/li>\n<\/ul>\n<p>T\u0103ng nguy c\u01a1 co gi\u1eadt<\/p>\n<h3><strong>3.3 Bi\u1ec7n ph\u00e1p x\u1eed l\u00fd<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">Tr\u00e1nh s\u1eed d\u1ee5ng Tramadol k\u1ebft h\u1ee3p v\u1edbi SSRI n\u1ebfu c\u00f3 th\u1ec3, ho\u1eb7c th\u1eadn tr\u1ecdng n\u1ebfu l\u1ee3i \u00edch ti\u1ec1m n\u0103ng \u0111\u01b0\u1ee3c coi l\u00e0 l\u1edbn h\u01a1n r\u1ee7i ro.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">B\u1ec7nh nh\u00e2n n\u00ean \u0111\u01b0\u1ee3c theo d\u00f5i ch\u1eb7t ch\u1ebd c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a h\u1ed9i ch\u1ee9ng serotonin trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">C\u1ea7n \u0111\u1eb7c bi\u1ec7t th\u1eadn tr\u1ecdng khi b\u1eaft \u0111\u1ea7u ho\u1eb7c t\u0103ng li\u1ec1u l\u01b0\u1ee3ng c\u1ee7a c\u00e1c thu\u1ed1c n\u00e0y. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Nguy c\u01a1 ti\u1ec1m \u1ea9n \u0111\u1ed1i v\u1edbi h\u1ed9i ch\u1ee9ng serotonin n\u00ean \u0111\u01b0\u1ee3c xem x\u00e9t ngay c\u1ea3 khi s\u1eed d\u1ee5ng tu\u1ea7n t\u1ef1 c\u00e1c thu\u1ed1c serotonergic, v\u00ec m\u1ed9t s\u1ed1 thu\u1ed1c c\u00f3 th\u1ec3 c\u00f3 th\u1eddi gian b\u00e1n th\u1ea3i k\u00e9o d\u00e0i (v\u00ed d\u1ee5: Fluoxetine, Vortioxetine).<\/span><\/p>\n<h3><strong>3.4 M\u1ee9c \u0111\u1ed9 t\u01b0\u01a1ng t\u00e1c thu\u1ed1c t\u1eeb nhi\u1ec1u ngu\u1ed3n kh\u00e1c nhau<\/strong><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drug: Nghi\u00eam tr\u1ecdng<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">WebMD: Nghi\u00eam tr\u1ecdng<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Medscape: Nghi\u00eam tr\u1ecdng<\/span><\/li>\n<\/ul>\n<h2><strong>4. K\u1ebft lu\u1eadn<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">D\u1ef1a tr\u00ean c\u00e1c nghi\u00ean c\u1ee9u hi\u1ec7n c\u00f3, t\u01b0\u01a1ng t\u00e1c gi\u1eefa Fluoxetin v\u00e0 Tramadol c\u00f3 th\u1ec3 g\u00e2y ra t\u0103ng c\u01b0\u1eddng t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a c\u1ea3 hai lo\u1ea1i thu\u1ed1c. Do \u0111\u00f3, c\u1ea7n c\u1ea9n tr\u1ecdng khi k\u1ebft h\u1ee3p s\u1eed d\u1ee5ng hai thu\u1ed1c n\u00e0y.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ngu\u1ed3n: D\u01b0\u1ee3c th\u01b0 Qu\u1ed1c gia Vi\u1ec7t Nam, Drug.com<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Fluoxetin v\u00e0 Tramadol l\u00e0 hai lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng ph\u1ed5 bi\u1ebfn trong \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd li\u00ean quan \u0111\u1ebfn r\u1ed1i lo\u1ea1n t\u00e2m l\u00fd v\u00e0 \u0111au. Tuy nhi\u00ean, khi k\u1ebft h\u1ee3p s\u1eed d\u1ee5ng hai lo\u1ea1i thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 g\u00e2y ra t\u01b0\u01a1ng t\u00e1c, t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb v\u00e0 t\u0103ng nguy c\u01a1 [&hellip;]<\/p>\n","protected":false},"author":53,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[12],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Fluoxetin v\u00e0 Tramadol - Vinmec<\/title>\n<meta name=\"description\" content=\"Fluoxetin v\u00e0 Tramadol l\u00e0 hai lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng ph\u1ed5 bi\u1ebfn trong \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd li\u00ean quan \u0111\u1ebfn r\u1ed1i lo\u1ea1n t\u00e2m l\u00fd v\u00e0 \u0111au\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Fluoxetin v\u00e0 Tramadol - 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