{"id":24724,"date":"2023-04-27T15:52:46","date_gmt":"2023-04-27T08:52:46","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=24724"},"modified":"2023-05-07T10:58:43","modified_gmt":"2023-05-07T03:58:43","slug":"benh-than-cap","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/27\/benh-than-cap\/","title":{"rendered":"B\u1ec7nh th\u1eadn c\u1ea5p t\u00ednh m\u1edbi kh\u1edfi ph\u00e1t sau khi ti\u00eam ph\u00f2ng COVID-19"},"content":{"rendered":"

Khi d\u1ecbch COVID-19 b\u00f9ng ph\u00e1t, vi\u1ec7c ti\u00eam vaccine COVID-19 tr\u1edf th\u00e0nh m\u1ed9t ph\u1ea7n quan tr\u1ecdng trong chi\u1ebfn l\u01b0\u1ee3c ph\u00f2ng ch\u1ed1ng d\u1ecbch b\u1ec7nh. Tuy nhi\u00ean, b\u1ec7nh th\u1eadn c\u1ea5p \u0111\u00e3 xu\u1ea5t hi\u1ec7n \u1edf m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p b\u1ec7nh nh\u00e2n sau khi ti\u00eam vaccine COVID-19, g\u00e2y lo ng\u1ea1i cho c\u00e1c chuy\u00ean gia y t\u1ebf v\u00e0 ng\u01b0\u1eddi d\u00e2n.<\/strong><\/p>\n

1. T\u1ed5ng qu\u00e1t v\u1ec1 b\u1ec7nh th\u1eadn c\u1ea5p t\u00ednh<\/strong><\/h1>\n

\u0110\u1ea1i d\u1ecbch b\u1ec7nh do virus corona 2019 (COVID-19) \u0111ang di\u1ec5n ra v\u00e0 s\u1ef1 xu\u1ea5t hi\u1ec7n c\u1ee7a c\u00e1c bi\u1ebfn th\u1ec3 m\u1edbi g\u00e2y ra h\u1ed9i ch\u1ee9ng h\u00f4 h\u1ea5p c\u1ea5p t\u00ednh n\u1eb7ng do virus corona ch\u1ee7ng 2 (SARS-CoV-2), vi\u1ec7c nhanh ch\u00f3ng ph\u00e1t tri\u1ec3n c\u00e1c lo\u1ea1i vaccine ph\u00f2ng ng\u1eeba an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 l\u00e0 r\u1ea5t c\u1ea7n thi\u1ebft \u0111\u1ec3 ki\u1ec3m so\u00e1t d\u1ecbch b\u1ec7nh b\u00f9ng ph\u00e1t. Trong 2 n\u0103m qua, h\u00e0ng tr\u0103m lo\u1ea1i vaccine COVID-19 \u0111\u00e3 \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n, th\u1eed nghi\u1ec7m v\u00e0 cu\u1ed1i c\u00f9ng \u0111\u01b0\u1ee3c tung ra th\u1ecb tr\u01b0\u1eddng, bao g\u1ed3m vaccine d\u1ef1a tr\u00ean Protein (Novavax), vaccine b\u1ea5t ho\u1ea1t (Sinovac Life Science), vaccine vector virus (Janssen, Oxford-AstraZeneca ) v\u00e0 vaccine mRNA (Pfizer\/BioNtech, Moderna, CureVac). Trong s\u1ed1 \u0111\u00f3, thu\u1ed1c d\u1ef1a tr\u00ean mRNA l\u00e0 m\u1edbi nh\u01b0ng kh\u00f4ng ph\u1ea3i l\u00e0 ch\u01b0a bi\u1ebft. vaccine mRNA cung c\u1ea5p mRNA chuy\u1ec3n gen th\u00f4ng qua c\u00e1c h\u1ea1t Nano Lipid, \u0111\u00f3ng vai tr\u00f2 l\u00e0 ch\u1ea5t mang. Sau khi \u0111\u01b0\u1ee3c ti\u00eam, mRNA \u0111\u01b0\u1ee3c d\u1ecbch m\u00e3 th\u00e0nh Protein m\u1ee5c ti\u00eau invivo, d\u1eabn \u0111\u1ebfn ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch m\u1ea1nh m\u1ebd v\u00e0 ph\u00e1c \u0111\u1ed3 2 li\u1ec1u mang l\u1ea1i kh\u1ea3 n\u0103ng b\u1ea3o v\u1ec7 95% ch\u1ed1ng l\u1ea1i COVID-19. Cho \u0111\u1ebfn nay, c\u00e1c th\u1eed nghi\u1ec7m l\u1edbn \u1edf giai \u0111o\u1ea1n III v\u00e0 IV \u0111\u00e3 cho th\u1ea5y c\u00e1c lo\u1ea1i vaccine n\u00e0y c\u00f3 t\u00ednh an to\u00e0n t\u1ed1t, \u00edt ph\u1ea3n \u1ee9ng nghi\u00eam tr\u1ecdng. C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 ng\u1eafn h\u1ea1n ph\u1ed5 bi\u1ebfn bao g\u1ed3m ph\u1ea3n \u1ee9ng t\u1ea1i ch\u1ed7 ti\u00eam, s\u1ed1t, m\u1ec7t m\u1ecfi, \u0111au to\u00e0n th\u00e2n v\u00e0 nh\u1ee9c \u0111\u1ea7u.<\/p>\n

Tuy nhi\u00ean, k\u1ec3 t\u1eeb khi ti\u00eam ch\u1ee7ng h\u00e0ng lo\u1ea1t, \u0111\u00e3 c\u00f3 m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p b\u00e1o c\u00e1o v\u1ec1 t\u1ed5n th\u01b0\u01a1ng th\u1eadn c\u1ea5p (AKI), b\u1ec7nh th\u1eadn c\u1ea5p (AKD), protein ni\u1ec7u, ph\u00f9, ti\u1ec3u m\u00e1u \u0111\u1ea1i th\u1ec3 v\u00e0 c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 kh\u00e1c \u1edf th\u1eadn c\u1ea7n nh\u1eadp vi\u1ec7n sau khi ti\u00eam vaccine COVID-19. N\u1ed3ng \u0111\u1ed9 creatinine huy\u1ebft thanh (Scr) v\u00e0 protein ni\u1ec7u ph\u1ee5c h\u1ed3i trong v\u00f2ng 3 th\u00e1ng \u0111i\u1ec1u tr\u1ecb \u1edf h\u1ea7u h\u1ebft b\u1ec7nh nh\u00e2n. Ph\u1ea7n l\u1edbn c\u00e1c tr\u01b0\u1eddng h\u1ee3p x\u1ea3y ra sau khi ti\u00eam vaccine mRNA v\u00e0 vect\u01a1 adenovirus, v\u00e0 m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p vi\u00eam c\u1ea7u th\u1eadn li\u00ean quan \u0111\u1ebfn vaccine virus b\u1ea5t ho\u1ea1t c\u0169ng \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o.<\/p>\n

Trong b\u00e0i \u0111\u00e1nh gi\u00e1 n\u00e0y, t\u00f3m t\u1eaft c\u00e1c \u0111\u1eb7c \u0111i\u1ec3m l\u00e2m s\u00e0ng c\u1ee7a AKD sau khi ti\u00eam vaccine c\u00f3 th\u1ec3 x\u1ea3y ra c\u1ee7a AKD sau khi ti\u00eam vaccine COVID-19.<\/p>\n

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Ngu\u1ed3n<\/strong>: New-Onset Acute Kidney Disease Post COVID-19 Vaccination<\/em><\/figcaption><\/figure>\n

2. \u0110\u1eb7c \u0111i\u1ec3m l\u00e2m s\u00e0ng c\u1ee7a b\u1ec7nh th\u1eadn c\u1ea5p t\u00ednh<\/strong><\/h2>\n

2.1. Sang th\u01b0\u01a1ng t\u1ed1i thi\u1ec3u (Minimal Change Disease – MCD)<\/strong><\/h3>\n

Trong s\u1ed1 t\u1ea5t c\u1ea3 c\u00e1c tr\u01b0\u1eddng h\u1ee3p \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o, MCD l\u00e0 lo\u1ea1i AKD b\u1ec7nh l\u00fd ph\u1ed5 bi\u1ebfn nh\u1ea5t sau khi ti\u00eam vaccine COVID -19, v\u1edbi t\u1ed5ng s\u1ed1 13 tr\u01b0\u1eddng h\u1ee3p (11 tr\u01b0\u1eddng h\u1ee3p m\u1edbi v\u00e0 02 tr\u01b0\u1eddng h\u1ee3p t\u00e1i ph\u00e1t). 06 b\u1ec7nh nh\u00e2n b\u1ecb t\u1ed5n th\u01b0\u01a1ng \u1ed1ng th\u1eadn c\u1ea5p v\u00e0\/ho\u1eb7c t\u1ed5n th\u01b0\u01a1ng k\u1ebd. 10 b\u1ec7nh nh\u00e2n b\u1ecb AKD sau l\u1ea7n ti\u00eam vaccine \u0111\u1ea7u ti\u00ean v\u00e0 03 b\u1ec7nh nh\u00e2n b\u1ecb AKD sau li\u1ec1u th\u1ee9 hai. Ph\u00f9 l\u00e0 tri\u1ec7u ch\u1ee9ng ph\u1ed5 bi\u1ebfn nh\u1ea5t. T\u1ea5t c\u1ea3 c\u00e1c b\u1ec7nh nh\u00e2n \u0111\u1ec1u \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng steroid v\u00e0 01 b\u1ec7nh nh\u00e2n c\u0169ng \u0111\u01b0\u1ee3c ch\u1ea1y th\u1eadn nh\u00e2n t\u1ea1o. M\u1ed9t b\u1ec7nh nh\u00e2n b\u1ecb MCD t\u00e1i ph\u00e1t kh\u00f4ng \u0111\u00e1p \u1ee9ng v\u1edbi Steroid li\u1ec1u cao \u0111\u00e3 nh\u1eadn \u0111\u01b0\u1ee3c Rituximab (RTX), v\u00e0 b\u1ec7nh nh\u00e2n \u0111\u00e3 \u0111\u00e1p \u1ee9ng. T\u1ed5ng c\u1ed9ng, 11 b\u1ec7nh nh\u00e2n thuy\u00ean gi\u1ea3m ho\u00e0n to\u00e0n ho\u1eb7c thuy\u00ean gi\u1ea3m m\u1ed9t ph\u1ea7n trong v\u00f2ng 03 th\u00e1ng \u0111i\u1ec1u tr\u1ecb, 01 b\u1ec7nh nh\u00e2n kh\u00f4ng c\u00f3 ph\u1ea3n \u1ee9ng v\u00e0 01 b\u1ec7nh nh\u00e2n kh\u00f4ng c\u00f3 h\u1ed3 s\u01a1 theo d\u00f5i.<\/p>\n

2.2. B\u1ec7nh th\u1eadn IgA<\/strong><\/h3>\n

11 tr\u01b0\u1eddng h\u1ee3p b\u1ec7nh th\u1eadn IgA (09 tr\u01b0\u1eddng h\u1ee3p kh\u1edfi ph\u00e1t m\u1edbi, 02 tr\u01b0\u1eddng h\u1ee3p t\u00e1i ph\u00e1t) \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o, trong \u0111\u00f3 ch\u1ec9 c\u00f3 01 b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh m\u1eafc AKI m\u00e0 kh\u00f4ng c\u00f3 AKD. M\u1ed9t tr\u01b0\u1eddng h\u1ee3p ph\u1ee9c t\u1ea1p v\u1edbi t\u00ecnh tr\u1ea1ng vi\u00eam th\u1eadn k\u1ebd c\u1ea5p t\u00ednh. Ti\u1ec3u m\u00e1u \u0111\u1ea1i th\u1ec3 l\u00e0 bi\u1ec3u hi\u1ec7n ph\u1ed5 bi\u1ebfn nh\u1ea5t. 06 b\u1ec7nh nh\u00e2n (04 ng\u01b0\u1eddi m\u1edbi, 02 ng\u01b0\u1eddi t\u00e1i ph\u00e1t) \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1ea3o t\u1ed3n, 04 ng\u01b0\u1eddi thuy\u00ean gi\u1ea3m ho\u00e0n to\u00e0n, 01 ng\u01b0\u1eddi kh\u00f4ng \u0111\u1ea1t Scr b\u00ecnh th\u01b0\u1eddng v\u00e0 m\u1ed9t ng\u01b0\u1eddi kh\u00f4ng c\u00f3 h\u1ed3 s\u01a1 theo d\u00f5i. 05 b\u1ec7nh nh\u00e2n m\u1edbi kh\u1edfi ph\u00e1t kh\u00e1c \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Steroid, 03 b\u1ec7nh nh\u00e2n \u0111\u00e1p \u1ee9ng v\u1edbi \u0111i\u1ec1u tr\u1ecb v\u00e0 02 b\u1ec7nh nh\u00e2n kh\u00f4ng c\u00f3 h\u1ed3 s\u01a1 theo d\u00f5i.<\/p>\n

2.3. B\u1ec7nh th\u1eadn m\u00e0ng (Membranous nephropathy \u2013 MN)<\/strong><\/h3>\n

MN \u0111\u00e3 \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n \u1edf 04 b\u1ec7nh nh\u00e2n (02 b\u1ec7nh nh\u00e2n m\u1edbi v\u00e0 02 b\u1ec7nh nh\u00e2n t\u00e1i ph\u00e1t) v\u00e0 03 b\u1ec7nh nh\u00e2n d\u01b0\u01a1ng t\u00ednh v\u1edbi kh\u00e1ng th\u1ec3 kh\u00e1ng th\u1ee5 th\u1ec3 kh\u00e1ng phospholipase A2 (PLA2R) trong huy\u1ebft thanh. T\u1ea5t c\u1ea3 c\u00e1c b\u1ec7nh nh\u00e2n \u0111\u1ec1u c\u00f3 tri\u1ec7u ch\u1ee9ng ph\u00f9 n\u1ec1. 01 b\u1ec7nh nh\u00e2n m\u1edbi kh\u1edfi ph\u00e1t \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1ea3o t\u1ed3n m\u00e0 kh\u00f4ng thuy\u00ean gi\u1ea3m trong v\u00f2ng 60 ng\u00e0y. 01 tr\u01b0\u1eddng h\u1ee3p m\u1edbi kh\u00e1c \u0111\u00e3 \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n, g\u1ed3m c\u00f3 MN v\u00e0 AKD sau khi ti\u00eam vaccine mRNA (Pfizer-BioNTech) \u0111\u1ea7u ti\u00ean, \u0111\u00e3 thuy\u00ean gi\u1ea3m m\u1ed9t ph\u1ea7n sau khi s\u1eed d\u1ee5ng thu\u1ed1c \u1ee9c ch\u1ebf h\u1ec7 th\u1ed1ng renin-angiotensin (RAS) v\u00e0 Scr kh\u00f4ng tr\u1edf l\u1ea1i m\u1ee9c ban \u0111\u1ea7u. Ph\u00f9 xu\u1ea5t hi\u1ec7n tr\u1edf l\u1ea1i sau l\u1ea7n ti\u00eam vaccine mRNA (Moderna) th\u1ee9 hai v\u00e0 Scr v\u1eabn \u1edf m\u1ee9c 1.15 mg\/dL. B\u1ec7nh nh\u00e2n sau \u0111\u00f3 \u0111\u00e3 \u0111\u01b0\u1ee3c d\u00f9ng Rituximab (RTX) v\u00e0 thuy\u00ean gi\u1ea3m m\u1ed9t ph\u1ea7n. M\u1ed9t tr\u01b0\u1eddng h\u1ee3p t\u00e1i ph\u00e1t \u0111\u00e3 \u0111\u00e1p \u1ee9ng v\u1edbi Tacrolimus (TAC) v\u00e0 Scr \u0111\u00e3 kh\u00f4ng tr\u1edf l\u1ea1i \u0111\u01b0\u1eddng c\u01a1 s\u1edf trong l\u1ea7n theo d\u00f5i cu\u1ed1i c\u00f9ng. B\u1ec7nh nh\u00e2n t\u00e1i ph\u00e1t kh\u00e1c kh\u00f4ng c\u00f3 h\u1ed3 s\u01a1 \u0111i\u1ec1u tr\u1ecb ho\u1eb7c theo d\u00f5i.<\/p>\n

2.4. Vi\u00eam m\u00e0ng \u0111\u00e1y c\u1ea7u th\u1eadn do kh\u00e1ng th\u1ec3 GBM (Anti-GBM) v\u00e0 kh\u00e1ng th\u1ec3 kh\u00e1ng t\u1ebf b\u00e0o Neutrophil (ANCA).<\/strong><\/h3>\n

Theo c\u00e1c b\u00e1o c\u00e1o trong y v\u0103n, \u0111\u00e3 c\u00f3 03 tr\u01b0\u1eddng h\u1ee3p vi\u00eam th\u1eadn kh\u00e1ng GBM m\u1edbi kh\u1edfi ph\u00e1t \u0111i\u1ec3n h\u00ecnh, k\u00e8m theo ti\u1ec3u m\u00e1u \u0111\u1ea1i th\u1ec3, t\u0103ng huy\u1ebft \u00e1p, ch\u00e1n \u0103n, bu\u1ed3n n\u00f4n, s\u1ed1t v\u00e0 c\u00e1c tri\u1ec7u ch\u1ee9ng kh\u00e1c. 01 tr\u01b0\u1eddng h\u1ee3p kh\u00f4ng \u0111\u00e1p \u1ee9ng v\u1edbi Mycophenolate v\u00e0 Steroid, v\u00e0 m\u1ee9c \u0111\u1ed9 Scr ti\u1ebfp t\u1ee5c t\u0103ng l\u00ean. 02 b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Cyclophosphamide (CyC), thay th\u1ebf huy\u1ebft t\u01b0\u01a1ng v\u00e0 b\u1ed5 sung Methylprednisolone, 01 b\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u00e1p \u1ee9ng v\u00e0 ti\u1ebfp t\u1ee5c l\u1ecdc m\u00e1u, v\u00e0 01 b\u1ec7nh nh\u00e2n c\u00f2n l\u1ea1i kh\u00f4ng c\u00f3 h\u1ed3 s\u01a1 theo d\u00f5i.<\/p>\n

Trong t\u00e0i li\u1ec7u, 08 tr\u01b0\u1eddng h\u1ee3p c\u00f3 vi\u00eam m\u1ea1ch m\u00e1u m\u1edbi kh\u1edfi ph\u00e1t do ANCA, 05 tr\u01b0\u1eddng h\u1ee3p c\u00f3 li\u00ean quan \u0111\u1ebfn Myeloperoxidase (MPO) v\u00e0 03 tr\u01b0\u1eddng h\u1ee3p c\u00f3 Proteinase 3 (PR3). Ngo\u00e0i ra, c\u00f3 01 b\u00e1o c\u00e1o v\u1ec1 vi\u00eam m\u1ea1ch u h\u1ea1t \u00e2m t\u00ednh ANCA sau li\u1ec1u ti\u00eam vaccine vec t\u01a1 Adenovirus (AstraZeneca) \u0111\u1ea7u ti\u00ean v\u00e0 Scr c\u1ee7a b\u1ec7nh nh\u00e2n tr\u1edf l\u1ea1i b\u00ecnh th\u01b0\u1eddng trong v\u00f2ng 2 th\u00e1ng. C\u1ea3 03 b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc b\u1ec7nh vi\u00eam m\u1ea1ch PR3-ANCA \u0111\u1ec1u xu\u1ea5t hi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng trong v\u00f2ng 01tu\u1ea7n sau khi ti\u00eam li\u1ec1u vaccine mRNA th\u1ee9 hai v\u00e0 sau \u0111\u00f3 \u0111\u01b0\u1ee3c nh\u1eadp vi\u1ec7n \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb. 01 tr\u01b0\u1eddng h\u1ee3p \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Rituximab, CyC, PSL v\u00e0 ch\u1ea1y th\u1eadn nh\u00e2n t\u1ea1o v\u00e0 \u0111\u01b0\u1ee3c ch\u1ea1y th\u1eadn nh\u00e2n t\u1ea1o m\u00e0 kh\u00f4ng thuy\u00ean gi\u1ea3m. Ngo\u00e0i ra, 01 tr\u01b0\u1eddng h\u1ee3p \u0111\u00e3 nh\u1eadn \u0111\u01b0\u1ee3c Glucocorticoid li\u1ec1u cao, CyC v\u00e0 thay th\u1ebf huy\u1ebft t\u01b0\u01a1ng v\u00e0 \u0111\u00e3 \u0111\u1ea1t \u0111\u01b0\u1ee3c s\u1ef1 thuy\u00ean gi\u1ea3m Scr trong v\u00f2ng 3 tu\u1ea7n v\u00e0 01 tr\u01b0\u1eddng h\u1ee3p \u0111\u00e3 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n li\u1ec7u ph\u00e1p Methylprednisolone, Rituximab, CyC v\u00e0 thay th\u1ebf huy\u1ebft t\u01b0\u01a1ng, v\u00e0 Scr \u0111\u00e3 gi\u1ea3m xu\u1ed1ng c\u00f2n 1.5 mg\/dL trong v\u00f2ng 10 tu\u1ea7n. T\u1eeb c\u00e1c y v\u0103n, c\u1ea3 b\u1ec7nh nh\u00e2n \u00e2m t\u00ednh v\u1edbi MPO-ANCA v\u00e0 ANCA b\u1ecb vi\u00eam m\u1ea1ch u h\u1ea1t \u0111\u1ec1u cho th\u1ea5y Scr \u0111\u01b0\u1ee3c c\u1ea3i thi\u1ec7n sau khi \u0111i\u1ec1u tr\u1ecb.<\/p>\n

2.5. Xu\u1ea5t huy\u1ebft gi\u1ea3m ti\u1ec3u c\u1ea7u mi\u1ec5n d\u1ecbch<\/strong><\/p>\n

Theo c\u00e1c b\u00e1o c\u00e1o, ch\u1ec9 c\u00f3 1\/8 b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o sau l\u1ea7n ti\u00eam ch\u1ee7ng th\u1ee9 hai. C\u00e1c tri\u1ec7u ch\u1ee9ng ch\u00ednh bao g\u1ed3m s\u1ed1t, nh\u1ee9c \u0111\u1ea7u, m\u1ec7t m\u1ecfi, b\u1ea7m m\u00e1u \u1edf tay ch\u00e2n v\u00e0 ph\u1ea3n \u1ee9ng ti\u00eau h\u00f3a, th\u01b0\u1eddng xu\u1ea5t hi\u1ec7n t\u1eeb 1 \u0111\u1ebfn 2 tu\u1ea7n sau khi ti\u00eam vaccine. Ngo\u1ea1i tr\u1eeb 01 tr\u01b0\u1eddng h\u1ee3p \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o b\u1edfi Al Rawahi et al, t\u1ea5t c\u1ea3 c\u00e1c tr\u01b0\u1eddng h\u1ee3p kh\u00e1c \u0111\u1ec1u \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb ngay l\u1eadp t\u1ee9c b\u1eb1ng \u00a0v\u00e0 li\u1ec7u ph\u00e1p \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch, ch\u1eb3ng h\u1ea1n nh\u01b0 Corticosteroid, Rituximab, v.v., v\u00e0 hi\u1ec7u qu\u1ea3 l\u00e2m s\u00e0ng nh\u00ecn chung l\u00e0 t\u1ed1t. Ngo\u00e0i ra, trong 03 tr\u01b0\u1eddng h\u1ee3p, li\u1ec1u \u0111\u1ea7u ti\u00ean c\u1ee7a vaccine COVID-19 \u0111\u00e3 t\u1ea1o ra n\u1ed3ng \u0111\u1ed9 IgG trung h\u00f2a cao ch\u1ed1ng l\u1ea1i SARS-CoV-2 . M\u1ee9c \u0111\u1ed9 ho\u1ea1t \u0111\u1ed9ng c\u1ee7a ADAMTS13 (A Disintegrin And Metalloproteinase with a ThromboSpondin type 1, member 13) \u0111\u00e3 gi\u1ea3m r\u00f5 r\u1ec7t v\u00e0 hi\u1ec7u gi\u00e1 c\u1ee7a ch\u1ea5t \u1ee9c ch\u1ebf t\u0103ng l\u00ean trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p. Do \u0111\u00f3, m\u1ed9t s\u1ed1 nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 suy \u0111o\u00e1n r\u1eb1ng \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n kh\u00f4ng m\u1eafc b\u1ec7nh n\u1ec1n, xu\u1ea5t huy\u1ebft gi\u1ea3m ti\u1ec3u c\u1ea7u mi\u1ec5n d\u1ecbch c\u00f3 li\u00ean quan \u0111\u1ebfn vi\u1ec7c ti\u00eam vaccine COVID-19.<\/p>\n

Ngu\u1ed3n tham kh\u1ea3o<\/strong>: New-Onset Acute Kidney Disease Post COVID-19 Vaccination<\/p>\n","protected":false},"excerpt":{"rendered":"

Khi d\u1ecbch COVID-19 b\u00f9ng ph\u00e1t, vi\u1ec7c ti\u00eam vaccine COVID-19 tr\u1edf th\u00e0nh m\u1ed9t ph\u1ea7n quan tr\u1ecdng trong chi\u1ebfn l\u01b0\u1ee3c ph\u00f2ng ch\u1ed1ng d\u1ecbch b\u1ec7nh. Tuy nhi\u00ean, b\u1ec7nh th\u1eadn c\u1ea5p \u0111\u00e3 xu\u1ea5t hi\u1ec7n \u1edf m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p b\u1ec7nh nh\u00e2n sau khi ti\u00eam vaccine COVID-19, g\u00e2y lo ng\u1ea1i cho c\u00e1c chuy\u00ean gia y t\u1ebf v\u00e0 ng\u01b0\u1eddi d\u00e2n. 1. […]<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[29,33],"tags":[],"yoast_head":"\nB\u1ec7nh th\u1eadn c\u1ea5p t\u00ednh m\u1edbi kh\u1edfi ph\u00e1t sau khi ti\u00eam ph\u00f2ng COVID-19<\/title>\n<meta name=\"description\" content=\"B\u1ec7nh th\u1eadn c\u1ea5p t\u00ednh \u0111\u00e3 xu\u1ea5t hi\u1ec7n trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p b\u1ec7nh nh\u00e2n sau khi ti\u00eam vaccine COVID-19, g\u00e2y lo ng\u1ea1i cho c\u00e1c chuy\u00ean gia y t\u1ebf\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"B\u1ec7nh th\u1eadn c\u1ea5p t\u00ednh m\u1edbi kh\u1edfi ph\u00e1t sau khi ti\u00eam ph\u00f2ng COVID-19\" \/>\n<meta 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