{"id":23738,"date":"2023-04-22T10:17:44","date_gmt":"2023-04-22T03:17:44","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=23738"},"modified":"2023-04-22T10:17:44","modified_gmt":"2023-04-22T03:17:44","slug":"tuong-tac-thuoc-giua-digoxin-va-ibuprofen","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/22\/tuong-tac-thuoc-giua-digoxin-va-ibuprofen\/","title":{"rendered":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Ibuprofen"},"content":{"rendered":"<p><strong>Digoxin v\u00e0 Ibuprofen l\u00e0 hai lo\u1ea1i thu\u1ed1c th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd kh\u00e1c nhau. Tuy nhi\u00ean, khi s\u1eed d\u1ee5ng c\u00f9ng l\u00fac, t\u01b0\u01a1ng t\u00e1c gi\u1eefa hai lo\u1ea1i thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Digoxin trong m\u00e1u, g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 v\u00e0 th\u1eadm ch\u00ed c\u00f3 th\u1ec3 nguy hi\u1ec3m \u0111\u1ebfn s\u1ee9c kh\u1ecfe c\u1ee7a b\u1ec7nh nh\u00e2n. Do \u0111\u00f3, vi\u1ec7c t\u0103ng c\u01b0\u1eddng gi\u00e1m s\u00e1t v\u00e0 h\u1ea1n ch\u1ebf t\u01b0\u01a1ng t\u00e1c gi\u1eefa hai lo\u1ea1i thu\u1ed1c n\u00e0y l\u00e0 c\u1ef1c k\u1ef3 quan tr\u1ecdng trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/strong><\/p>\n<h2><strong>1. Th\u00f4ng tin chung v\u1ec1 Digoxin v\u00e0 Ibuprofen<\/strong><\/h2>\n<h3><strong>1.1. Digoxin<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">D\u01b0\u1ee3c l\u00fd v\u00e0 c\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Digoxin l\u00e0 m\u1ed9t glycosid tr\u1ee3 tim thu t\u1eeb l\u00e1 Digitalis lanata. Thu\u1ed1c n\u00e0y hi\u1ec7n nay th\u01b0\u1eddng \u0111\u01b0\u1ee3c d\u00f9ng h\u01a1n Digitoxin. C\u1ea3 hai thu\u1ed1c n\u00e0y \u0111\u1ec1u c\u00f3 t\u00e1c d\u1ee5ng d\u01b0\u1ee3c l\u00fd gi\u1ed1ng nhau, nh\u01b0ng kh\u00e1c nhau v\u1ec1 \u0111\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">T\u00e1c d\u1ee5ng ch\u00ednh c\u1ee7a Digoxin l\u00e0 l\u00e0m t\u0103ng l\u1ef1c co b\u00f3p c\u01a1 tim v\u00e0 l\u00e0m t\u0103ng l\u01b0u l\u01b0\u1ee3ng tim. T\u0103ng t\u00ednh co b\u00f3p c\u01a1 tim l\u00e0 do Digoxin \u1ee9c ch\u1ebf b\u01a1m Na+\/K+ ATPase \u01a1\u0309 m\u00e0ng c\u01a1 tim l\u00e0m cho s\u1ef1 trao \u0111\u00f4\u0309i Natri trong t\u1ebf b\u00e0o v\u1edbi Kali ngo\u00e0i t\u1ebf b\u00e0o nh\u1eb1m c\u00e2n b\u1eb1ng ion b\u1ecb \u1ee9c ch\u1ebf. H\u1eadu qu\u1ea3 l\u00e0 t\u0103ng Calci n\u1ed9i b\u00e0o \u0111i qua k\u00eanh Calci ch\u1eadm v\u00e0 gi\u1ea3m ho\u1ea1t \u0111\u1ed9ng c\u1ee7a b\u01a1m trao \u0111\u00f4\u0309i Natri \u2013 Calci ra ngo\u00e0i t\u1ebf b\u00e0o. Khi l\u01b0\u1ee3ng Calci n\u1ed9i b\u00e0o t\u0103ng l\u00ean s\u1ebd s\u1eed d\u1ee5ng nhi\u1ec1u h\u01a1n cho b\u1ed9 m\u00e1y co c\u01a1, l\u00e0m t\u0103ng co c\u01a1. Digoxin l\u00e0m gi\u1ea3m t\u00ednh d\u1eabn truy\u1ec1n c\u1ee7a tim, \u0111\u1eb7c bi\u1ec7t l\u00e0 d\u1eabn truy\u1ec1n qua n\u00fat nh\u0129 th\u1ea5t. Digoxin c\u0169ng c\u00f3 t\u00e1c d\u1ee5ng tr\u1ef1c ti\u1ebfp l\u00ean c\u01a1 tr\u01a1n m\u1ea1ch m\u00e1u v\u00e0 c\u00f3 t\u00e1c d\u1ee5ng gi\u00e1n ti\u1ebfp tr\u00ean h\u1ec7 th\u1ea7n kinh t\u1ef1 ch\u1ee7, v\u00e0 \u0111\u1eb7c bi\u1ec7t g\u00e2y t\u0103ng ho\u1ea1t t\u00ednh th\u1ea7n kinh \u0111\u1ed1i giao c\u1ea3m. Gi\u1ea3m ho\u1ea1t t\u00ednh th\u1ea7n kinh giao c\u1ea3m. T\u0103ng t\u00ednh k\u00edch th\u00edch s\u1ee3i c\u01a1 tim ngay trong li\u1ec1u \u0111i\u1ec1u tr\u1ecb do r\u00fat ng\u1eafn th\u1eddi gian tr\u01a1, t\u0103ng t\u00ednh t\u1ef1 \u0111\u1ed9ng t\u1ebf b\u00e0o.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Trong suy tim, l\u01b0u l\u01b0\u1ee3ng tim t\u0103ng l\u00e0 nh\u1edd t\u00e1c d\u1ee5ng co c\u01a1 tim v\u00e0 t\u00e1c d\u1ee5ng ngo\u00e0i tim (gi\u1ea3m ho\u1ea1t t\u00ednh h\u1ec7 th\u1ea7n kinh giao c\u1ea3m) d\u1eabn \u0111\u1ebfn gi\u1ea3m ti\u1ec1n g\u00e1nh v\u00e0 h\u1eadu g\u00e1nh.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Digoxin c\u1ea3i thi\u1ec7n \u0111\u01b0\u1ee3c c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a suy tim, t\u0103ng dung n\u1ea1p v\u1edbi g\u1eafng s\u1ee9c, gi\u1ea3m t\u1ef7 l\u1ec7 nh\u1eadp vi\u1ec7n nh\u01b0ng kh\u00f4ng gi\u1ea3m \u0111\u01b0\u1ee3c t\u1ef7 l\u1ec7 t\u1eed vong. Digoxin \u0111\u01b0\u1ee3c d\u00e0nh cho ng\u01b0\u1eddi suy tim c\u00f3 rung nh\u0129 v\u00e0 m\u1ed9t s\u1ed1 suy tim c\u00f3 nh\u1ecbp xoang m\u1eb7c d\u00f9 \u0111\u00e3 d\u00f9ng thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n, ch\u1eb9n beta v\u00e0 l\u1ee3i ti\u1ec3u.<\/span><\/li>\n<\/ul>\n<figure id=\"attachment_23757\" aria-describedby=\"caption-attachment-23757\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-23757\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/20200612_081033_166044_digoxin-richter-50v.max-1800x1800-2-300x200.jpg\" alt=\"Digoxin\" width=\"300\" height=\"200\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/20200612_081033_166044_digoxin-richter-50v.max-1800x1800-2-300x200.jpg 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/20200612_081033_166044_digoxin-richter-50v.max-1800x1800-2.jpg 700w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-23757\" class=\"wp-caption-text\">Digoxin<\/figcaption><\/figure>\n<h3><strong>1.2. Ibuprofen<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">D\u01b0\u1ee3c l\u00fd v\u00e0 c\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ibuprofen l\u00e0 thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid (NSAID), d\u1eabn xu\u1ea5t t\u1eeb Acid propionic. T\u01b0\u01a1ng t\u1ef1 nh\u01b0 c\u00e1c thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid kh\u00e1c, Ibuprofen c\u00f3 t\u00e1c d\u1ee5ng gi\u1ea3m \u0111au, h\u1ea1 s\u1ed1t v\u00e0 ch\u1ed1ng vi\u00eam. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c l\u00e0 \u1ee9c ch\u1ebf enzym prostaglandin synthetase v\u00e0 do \u0111\u00f3 ng\u0103n t\u1ea1o ra prostaglandin, thromboxan v\u00e0 c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a enzym cyclooxygenase. Ibuprofen c\u0169ng \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p prostacyclin \u1edf th\u1eadn v\u00e0 c\u00f3 th\u1ec3 g\u00e2y nguy c\u01a1 \u1ee9 n\u01b0\u1edbc do l\u00e0m gi\u1ea3m d\u00f2ng m\u00e1u t\u1edbi th\u1eadn. C\u1ea7n ph\u1ea3i l\u01b0u \u00fd \u0111\u1ebfn \u0111i\u1ec1u n\u00e0y khi ch\u1ec9 \u0111\u1ecbnh cho ng\u01b0\u1eddi b\u1ec7nh c\u00f3 suy th\u1eadn, suy tim, suy gan v\u00e0 c\u00e1c b\u1ec7nh c\u00f3 r\u1ed1i lo\u1ea1n v\u1ec1 th\u1ec3 t\u00edch huy\u1ebft t\u01b0\u01a1ng.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">T\u00e1c d\u1ee5ng ch\u1ed1ng vi\u00eam c\u1ee7a Ibuprofen xu\u1ea5t hi\u1ec7n sau hai ng\u00e0y \u0111i\u1ec1u tr\u1ecb. Ibuprofen c\u00f3 t\u00e1c d\u1ee5ng h\u1ea1 s\u1ed1t m\u1ea1nh h\u01a1n Aspirin, nh\u01b0ng k\u00e9m Indomethacin. Thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng ch\u1ed1ng vi\u00eam t\u1ed1t v\u00e0 c\u00f3 t\u00e1c d\u1ee5ng gi\u1ea3m \u0111au t\u1ed1t trong \u0111i\u1ec1u tr\u1ecb vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p thi\u1ebfu ni\u00ean.<\/span><\/li>\n<\/ul>\n<figure id=\"attachment_23760\" aria-describedby=\"caption-attachment-23760\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-23760\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Ibuprofen-1-300x200.jpg\" alt=\"Ibuprofen\" width=\"300\" height=\"200\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Ibuprofen-1-300x200.jpg 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Ibuprofen-1.jpg 768w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-23760\" class=\"wp-caption-text\">Ibuprofen<\/figcaption><\/figure>\n<h2><strong>2. Ch\u1ec9 \u0111\u1ecbnh c\u1ee7a Digoxin v\u00e0 Ibuprofen<\/strong><\/h2>\n<h3><strong>2.1. Digoxin<\/strong><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Suy tim.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lo\u1ea1n nh\u1ecbp nhanh tr\u00ean th\u1ea5t (cu\u1ed3ng nh\u0129, rung nh\u0129, nh\u1ecbp nhanh tr\u00ean th\u1ea5t).<\/span><\/li>\n<\/ul>\n<h3><strong>2.2. Ibuprofen<\/strong><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gi\u1ea3m \u0111au v\u00e0 ch\u1ed1ng vi\u00eam t\u1eeb nh\u1eb9 \u0111\u1ebfn v\u1eeba: Trong m\u1ed9t s\u1ed1 b\u1ec7nh nh\u01b0 \u0111au \u0111\u1ea7u, \u0111au r\u0103ng. D\u00f9ng Ibuprofen c\u00f3 th\u1ec3 gi\u1ea3m b\u1edbt li\u1ec1u thu\u1ed1c ch\u1ee9a thu\u1ed1c phi\u1ec7n trong \u0111i\u1ec1u tr\u1ecb \u0111au sau \u0111\u1ea1i ph\u1eabu thu\u1eadt hay \u0111au do ung th\u01b0. Vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p, vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p thi\u1ebfu ni\u00ean.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">H\u1ea1 s\u1ed1t \u1edf tr\u1ebb em.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ch\u1ee9ng c\u00f2n \u1ed1ng \u0111\u1ed9ng m\u1ea1ch (PDA) \u1edf tr\u1ebb s\u01a1 sinh thi\u1ebfu th\u00e1ng, d\u01b0\u1edbi 34 tu\u1ea7n. \u0110au b\u1ee5ng kinh.<\/span><\/li>\n<\/ul>\n<h2><strong>3. T\u01b0\u01a1ng t\u00e1c gi\u1eefa Digoxin v\u00e0 Ibuprofen<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">Thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid (NSAID) l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Digoxin trong huy\u1ebft t\u01b0\u01a1ng v\u00e0 th\u1eddi gian b\u00e1n th\u1ea3i b\u1eb1ng c\u00e1ch gi\u1ea3m \u0111\u1ed9 thanh th\u1ea3i c\u1ee7a th\u1eadn. \u0110i\u1ec1u n\u00e0y l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng ph\u1ee5 v\u00e0 \u0111\u1ed9c t\u00ednh c\u1ee7a Digoxin.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Digoxin v\u00e0 Ibuprofen \u0111\u1ec1u l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Kali trong m\u00e1u. C\u01a1 ch\u1ebf ch\u00ednh x\u00e1c ch\u01b0a r\u00f5 r\u00e0ng, tuy nhi\u00ean c\u00f3 th\u1ec3 do \u1ea3nh h\u01b0\u1edfng c\u1ee7a c\u00e1c thu\u1ed1c n\u00e0y \u0111\u1ebfn vi\u1ec7c th\u1ea3i Kali qua th\u1eadn. Vi\u1ec7c t\u0103ng n\u1ed3ng \u0111\u1ed9 Kali trong m\u00e1u c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">M\u1ee9c \u0111\u1ed9 t\u01b0\u01a1ng t\u00e1c t\u1eeb nhi\u1ec1u ngu\u1ed3n kh\u00e1c nhau:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drug: V\u1eeba ph\u1ea3i<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">WebMD: c\u00f3 2 m\u1ee9c \u0111\u1ed9. M\u1ed9t l\u00e0 m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng do t\u01b0\u01a1ng t\u00e1c gi\u1eefa hai thu\u1ed1c \u0111\u1ec1u l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Kali m\u00e1u. Hai l\u00e0 m\u1ee9c \u0111\u1ed9 nh\u1eb9 do Ibuprofen l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Digoxin<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Medscape: c\u00f3 2 m\u1ee9c \u0111\u1ed9. M\u1ed9t l\u00e0 m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng do t\u01b0\u01a1ng t\u00e1c hai thu\u1ed1c \u0111\u1ec1u l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Kali m\u00e1u. Hai l\u00e0 m\u1ee9c \u0111\u1ed9 nh\u1eb9 do Ibuprofen l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Digoxin<\/span><\/li>\n<\/ul>\n<h2><strong>4. T\u00e1c d\u1ee5ng ph\u1ee5<\/strong><\/h2>\n<h3><strong>4.1 T\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a Digoxin<\/strong><\/h3>\n<p><b><i>Th\u01b0\u1eddng g\u1eb7p:<\/i><\/b><span style=\"font-weight: 400;\"> Ch\u00e1n \u0103n, bu\u1ed3n n\u00f4n, n\u00f4n. <\/span><\/p>\n<p><b><i>\u00cdt g\u1eb7p:<\/i><\/b><span style=\"font-weight: 400;\"> Nh\u1ecbp tim ch\u1eadm xoang, block nh\u0129 \u2013 th\u1ea5t, block xoang nh\u0129, ngo\u1ea1i t\u00e2m thu nh\u0129 ho\u1eb7c n\u00fat, lo\u1ea1n nh\u1ecbp th\u1ea5t, nh\u1ecbp \u0111\u00f4i, nh\u1ecbp ba, nh\u1ecbp nhanh nh\u0129 v\u1edbi block nh\u0129 \u2013 th\u1ea5t, ng\u1ee7 l\u01a1 m\u01a1, nh\u1ee9c \u0111\u1ea7u, m\u1ec7t m\u1ecfi, ng\u1ee7 l\u1ecbm, ch\u00f3ng m\u1eb7t, m\u1ea5t ph\u01b0\u01a1ng h\u01b0\u1edbng, t\u0103ng Kali huy\u1ebft v\u1edbi ng\u1ed9 \u0111\u1ed9c c\u1ea5p, kh\u00f4ng dung n\u1ea1p th\u1ee9c \u0103n, \u0111au b\u1ee5ng, \u1ec9a ch\u1ea3y, \u0111au d\u00e2y th\u1ea7n kinh, nh\u00ecn m\u1edd, nh\u00ecn v\u00e0ng ho\u1eb7c xanh l\u00e1 c\u00e2y, nh\u00ecn \u0111\u00f4i, s\u1ee3 \u00e1nh s\u00e1ng, \u00e1nh s\u00e1ng l\u00f3e l\u00ean.<\/span><\/p>\n<h3><strong>4.2 T\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a Ibuprofen<\/strong><\/h3>\n<p><b><i>Th\u01b0\u1eddng g\u1eb7p:<\/i><\/b><span style=\"font-weight: 400;\"> S\u1ed1t, m\u1ecfi m\u1ec7t, ch\u01b0\u1edbng b\u1ee5ng, bu\u1ed3n n\u00f4n, n\u00f4n, nh\u1ee9c \u0111\u1ea7u, hoa m\u1eaft ch\u1ed1ng m\u1eb7t, m\u1ea9n ng\u1ee9a, ngo\u1ea1i ban. <\/span><\/p>\n<p><b><i>\u00cdt g\u1eb7p:<\/i><\/b><span style=\"font-weight: 400;\"> Ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng, vi\u00eam m\u0169i, n\u1ed5i m\u00e0y \u0111ay, \u0111au b\u1ee5ng, ch\u1ea3y m\u00e1u d\u1ea1 d\u00e0y \u2013 ru\u1ed9t, l\u00e0m lo\u00e9t d\u1ea1 d\u00e0y ti\u1ebfn tri\u1ec3n, l\u01a1 m\u01a1, m\u1ea5t ng\u1ee7, \u00f9 tai, r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c, th\u00ednh l\u1ef1c gi\u1ea3m, th\u1eddi gian ch\u1ea3y m\u00e1u k\u00e9o d\u00e0i. <\/span><\/p>\n<p><b><i>Hi\u1ebfm g\u1eb7p: <\/i><\/b><span style=\"font-weight: 400;\">Ph\u00f9, n\u1ed5i ban, h\u1ed9i ch\u1ee9ng Stevens \u2013 Johnson, r\u1ee5ng t\u00f3c, h\u1ea1 Natri, tr\u1ea7m c\u1ea3m, vi\u00eam m\u00e0ng n\u00e3o v\u00f4 khu\u1ea9n v\u00e0 h\u00f4n m\u00ea, nh\u00ecn m\u1edd, r\u1ed1i lo\u1ea1n nh\u00ecn m\u00e0u, gi\u1ea3m th\u1ecb l\u1ef1c do ng\u1ed9 \u0111\u1ed9c thu\u1ed1c, gi\u1ea3m b\u1ea1ch c\u1ea7u, gi\u1ea3m ti\u1ec3u c\u1ea7u, gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh, t\u0103ng b\u1ea1ch c\u1ea7u \u01b0a \u00e1i toan, gi\u1ea3m b\u1ea1ch c\u1ea7u h\u1ea1t, thi\u1ebfu m\u00e1u, r\u1ed1i lo\u1ea1n co b\u00f3p t\u00fai m\u1eadt, c\u00e1c th\u1eed nghi\u1ec7m th\u0103m d\u00f2 ch\u1ee9c n\u0103ng gan b\u1ea5t th\u01b0\u1eddng, nhi\u1ec5m \u0111\u1ed9c gan. Vi\u00eam ru\u1ed9t ho\u1ea1i t\u1eed, h\u1ed9i ch\u1ee9ng Crohn, vi\u00eam t\u1ee5y, vi\u00eam b\u00e0ng quang, xu\u1ea5t huy\u1ebft \u0111\u01b0\u1eddng ni\u1ec7u, suy th\u1eadn c\u1ea5p, vi\u00eam th\u1eadn k\u1ebd, h\u1ed9i ch\u1ee9ng th\u1eadn h\u01b0, nh\u1ea1y c\u1ea3m v\u1edbi \u00e1nh s\u00e1ng.<\/span><\/p>\n<h3><strong>4.3 T\u00e1c d\u1ee5ng ph\u1ee5 c\u00f3 th\u1ec3 x\u1ea3y ra khi s\u1eed d\u1ee5ng Digoxin v\u00e0 Ibuprofen c\u00f9ng nhau<\/strong><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bu\u1ed3n n\u00f4n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ch\u00e1n \u0103n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Thay \u0111\u1ed5i th\u1ecb l\u1ef1c<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">M\u1ea1ch ch\u1eadm ho\u1eb7c nh\u1ecbp tim kh\u00f4ng \u0111\u1ec1u.<\/span><\/li>\n<\/ul>\n<h2><strong>5. Bi\u1ec7n ph\u00e1p x\u1eed l\u00fd<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">B\u1ec7nh nh\u00e2n c\u1ea7n \u0111i\u1ec1u tr\u1ecb \u0111\u1ed3ng th\u1eddi hai thu\u1ed1c n\u00e0y n\u00ean \u0111\u01b0\u1ee3c theo d\u00f5i v\u1ec1 t\u00e1c d\u1ee5ng d\u01b0\u1ee3c l\u00fd thay \u0111\u1ed5i c\u1ee7a Digoxin v\u00e0 t\u0103ng n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng. Li\u1ec1u l\u01b0\u1ee3ng Digoxin c\u00f3 th\u1ec3 y\u00eau c\u1ea7u \u0111i\u1ec1u ch\u1ec9nh.<\/span><\/p>\n<h2><strong>\u00a06. K\u1ebft lu\u1eadn<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">T\u01b0\u01a1ng t\u00e1c gi\u1eefa Digoxin v\u00e0 Ibuprofen c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Digoxin trong m\u00e1u, g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 v\u00e0 nguy hi\u1ec3m \u0111\u1ebfn s\u1ee9c kh\u1ecfe c\u1ee7a b\u1ec7nh nh\u00e2n. Vi\u1ec7c gi\u00e1m s\u00e1t v\u00e0 h\u1ea1n ch\u1ebf t\u01b0\u01a1ng t\u00e1c gi\u1eefa hai lo\u1ea1i thu\u1ed1c n\u00e0y l\u00e0 c\u1ef1c k\u1ef3 c\u1ea7n thi\u1ebft \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ngu\u1ed3n: D\u01b0\u1ee3c th\u01b0 Qu\u1ed1c gia Vi\u1ec7t Nam, Drug.com<\/span><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Digoxin v\u00e0 Ibuprofen l\u00e0 hai lo\u1ea1i thu\u1ed1c th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd kh\u00e1c nhau. Tuy nhi\u00ean, khi s\u1eed d\u1ee5ng c\u00f9ng l\u00fac, t\u01b0\u01a1ng t\u00e1c gi\u1eefa hai lo\u1ea1i thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Digoxin trong m\u00e1u, g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 v\u00e0 th\u1eadm ch\u00ed c\u00f3 th\u1ec3 nguy hi\u1ec3m [&hellip;]<\/p>\n","protected":false},"author":53,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[12],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Ibuprofen - Vinmec<\/title>\n<meta name=\"description\" content=\"Digoxin v\u00e0 Ibuprofen l\u00e0 hai lo\u1ea1i thu\u1ed1c th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd kh\u00e1c nhau. 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