{"id":23130,"date":"2023-04-19T13:23:25","date_gmt":"2023-04-19T06:23:25","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=23130"},"modified":"2023-04-19T14:41:33","modified_gmt":"2023-04-19T07:41:33","slug":"10-dac-tinh-cua-ung-thu-ung-dung-trong-dieu-tri","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/19\/10-dac-tinh-cua-ung-thu-ung-dung-trong-dieu-tri\/","title":{"rendered":"10 \u0110\u1eb7c T\u00ednh C\u1ee7a Ung Th\u01b0- \u1ee8ng D\u1ee5ng Trong \u0110i\u1ec1u Tr\u1ecb"},"content":{"rendered":"<p>Ung th\u01b0 l\u00e0 m\u1ed9t c\u0103n b\u1ec7nh ph\u1ee9c t\u1ea1p li\u00ean quan \u0111\u1ebfn nhi\u1ec1u qu\u00e1 tr\u00ecnh sinh h\u1ecdc, bao g\u1ed3m vi\u1ec7c t\u00edch l\u0169y m\u1ed9t s\u1ed1 \u0111\u1eb7c t\u00ednh c\u1ee7a t\u1ebf b\u00e0o ung th\u01b0 (hallmarks of cancer). N\u0103m 2000, Douglas Hanahan v\u00e0 Robert Weinberg \u0111\u1ec1 xu\u1ea5t m\u1ed9t l\u00fd thuy\u1ebft \u0111\u1ec3 mi\u00eau t\u1ea3 nh\u1eefng \u0111\u1eb7c t\u00ednh c\u1ee7a ung th\u01b0, bao g\u1ed3m s\u00e1u \u0111\u1eb7c t\u00ednh c\u01a1 b\u1ea3n m\u00e0 t\u1ebf b\u00e0o \u00e1c t\u00ednh th\u01b0\u1eddng c\u00f3 trong qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n b\u1ec7nh. Sau \u0111\u00f3, l\u00fd thuy\u1ebft n\u00e0y \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadt \u0111\u1ec3 bao g\u1ed3m b\u1ed1n \u0111\u1eb7c t\u00ednh b\u1ed5 sung, d\u1eabn \u0111\u1ebfn m\u00f4 h\u00ecnh hi\u1ec7n t\u1ea1i v\u1ec1 t\u00e1m \u0111\u1eb7c t\u00ednh c\u1ee7a ung th\u01b0. L\u00fd thuy\u1ebft c\u00e1c \u0111\u1eb7c t\u00ednh c\u1ee7a ung th\u01b0 cung c\u1ea5p m\u1ed9t n\u1ec1n t\u1ea3ng to\u00e0n di\u1ec7n \u0111\u1ec3 hi\u1ec3u c\u00e1c c\u01a1 ch\u1ebf ph\u00e2n t\u1eed th\u00fac \u0111\u1ea9y s\u1ef1 ph\u00e1t tri\u1ec3n v\u00e0 ti\u1ebfn tri\u1ec3n c\u1ee7a c\u00e1c t\u1ebf b\u00e0o \u00e1c t\u00ednh v\u00e0 m\u1edf ra nh\u1eefng m\u1ee5c ti\u00eau \u0111i\u1ec1u tr\u1ecb ti\u1ec1m n\u0103ng m\u1edbi cho c\u0103n b\u1ec7nh n\u00e0y.<\/p>\n<ol>\n<li>\n<h2><strong>C\u00e1c \u0111\u1eb7c t\u00ednh c\u1ee7a ung th\u01b0<\/strong><\/h2>\n<\/li>\n<\/ol>\n<ul>\n<li><em>T<\/em><em>\u00edn hi\u1ec7u ph\u00e2n chia k\u00e9o d\u00e0i:<\/em> T\u1ebf b\u00e0o ung th\u01b0 c\u00f3 \u0111\u01b0\u1ee3c kh\u1ea3 n\u0103ng ph\u00e2n chia kh\u00f4ng ki\u1ec3m so\u00e1t b\u1eb1ng c\u00e1ch k\u00edch ho\u1ea1t c\u00e1c gen ti\u1ec1n ung th\u01b0. V\u00ed d\u1ee5 v\u1ec1 \u0111\u1eb7c \u0111i\u1ec3m n\u00e0y bao g\u1ed3m \u0111\u1ed9t bi\u1ebfn trong gene EGFR \u0111\u01b0\u1ee3c quan s\u00e1t trong ung th\u01b0 ph\u1ed5i v\u00e0 \u0111\u1ed9t bi\u1ebfn t\u0103ng c\u01b0\u1eddng HER2 trong ung th\u01b0 v\u00fa.<\/li>\n<li><em>Tr\u00e1nh \u0111\u01b0\u1ee3c nh\u1eefng ch\u1ea5t \u1ee9c ch\u1ebf ph\u00e1t tri\u1ec3n:<\/em> T\u1ebf b\u00e0o ung th\u01b0 c\u00f3 th\u1ec3 tr\u00e1nh \u0111\u01b0\u1ee3c c\u00e1c c\u01a1 ch\u1ebf ng\u0103n ch\u1eb7n ch\u00fang ph\u00e2n chia kh\u00f4ng ki\u1ec3m so\u00e1t b\u1eb1ng c\u00e1ch v\u00f4 hi\u1ec7u h\u00f3a gen \u1ee9c ch\u1ebf kh\u1ed1i u. V\u00ed d\u1ee5, \u0111\u1ed9t bi\u1ebfn trong gene TP53 \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong nhi\u1ec1u lo\u1ea1i ung th\u01b0.<\/li>\n<li><em>Ch\u1ed1ng l\u1ea1i s\u1ef1 ch\u1ebft t\u1ebf b\u00e0o:<\/em> T\u1ebf b\u00e0o ung th\u01b0 c\u00f3 th\u1ec3 tr\u00e1nh \u0111\u01b0\u1ee3c s\u1ef1 ch\u1ebft theo ch\u01b0\u01a1ng tr\u00ecnh b\u1eb1ng vi\u1ec7c t\u0103ng bi\u1ec3u hi\u1ec7n protein \u1ee9c ch\u1ebf ch\u1ebft theo ch\u01b0\u01a1ng tr\u00ecnh, ch\u1eb3ng h\u1ea1n nh\u01b0 BCL-2.<\/li>\n<li><em>K\u00edch ho\u1ea1t kh\u1ea3 n\u0103ng sao ch\u00e9p li\u00ean t\u1ee5c:<\/em> T\u1ebf b\u00e0o ung th\u01b0 c\u00f3 th\u1ec3 v\u01b0\u1ee3t qua gi\u1edbi h\u1ea1n b\u00ecnh th\u01b0\u1eddng v\u1ec1 s\u1ed1 l\u1ea7n t\u1ebf b\u00e0o c\u00f3 th\u1ec3 ph\u00e2n chia b\u1eb1ng c\u00e1ch ho\u1ea1t h\u00f3a telomerase ho\u1eb7c c\u00e1c c\u01a1 ch\u1ebf k\u00e9o d\u00e0i \u0111o\u1ea1n telomere.<\/li>\n<li><em>K\u00edch ho\u1ea1t s\u1ef1 h\u00ecnh th\u00e0nh m\u1ea1ch m\u00e1u m\u1edbi:<\/em> T\u1ebf b\u00e0o ung th\u01b0 c\u00f3 th\u1ec3 ho\u1ea1t h\u00f3a qu\u00e1 tr\u00ecnh h\u00ecnh th\u00e0nh m\u1ea1ch m\u00e1u m\u1edbi b\u1eb1ng c\u00e1ch ti\u1ebft ra c\u00e1c y\u1ebfu t\u1ed1 t\u0103ng sinh m\u1ea1ch, ch\u1eb3ng h\u1ea1n nh\u01b0 VEGF.<\/li>\n<li><em>K\u00edch ho\u1ea1t x\u00e2m l\u1ea5n m\u00f4 v\u00e0 di c\u0103n:<\/em> T\u1ebf b\u00e0o ung th\u01b0 c\u00f3 th\u1ec3 t\u00edch l\u0169y kh\u1ea3 n\u0103ng x\u00e2m l\u1ea5n c\u00e1c m\u00f4 xung quanh v\u00e0 di c\u0103n t\u1edbi c\u00e1c c\u01a1 quan xa.<\/li>\n<li><em>T\u00e1i l\u1eadp l\u1ea1i c\u01a1 ch\u1ebf trao \u0111\u1ed5i ch\u1ea5t:<\/em> T\u1ebf b\u00e0o ung th\u01b0 tr\u1ea3i qua s\u1ef1 chuy\u1ec3n \u0111\u1ed5i c\u01a1 ch\u1ebf trao \u0111\u1ed5i ch\u1ea5t ch\u00ednh sang \u0111\u01b0\u1eddng ph\u00e2n, c\u00f2n g\u1ecdi l\u00e0 hi\u1ec7u \u1ee9ng Warburg, cho ph\u00e9p ch\u00fang t\u1ea1o ra n\u0103ng l\u01b0\u1ee3ng hi\u1ec7u qu\u1ea3 h\u01a1n trong \u0111i\u1ec1u ki\u1ec7n thi\u1ebfu O2.<\/li>\n<li><em>Tr\u00e1nh b\u1ecb ph\u00e1 h\u1ee7y b\u1edfi h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch:<\/em> T\u1ebf b\u00e0o ung th\u01b0 c\u00f3 th\u1ec3 tr\u00e1nh \u0111\u01b0\u1ee3c gi\u00e1m s\u00e1t mi\u1ec5n d\u1ecbch b\u1eb1ng c\u00e1ch gi\u1ea3m b\u1edbt ho\u1eb7c \u0111\u1ed9t bi\u1ebfn kh\u00e1ng nguy\u00ean, \u1ee9c ch\u1ebf ho\u1ea1t \u0111\u1ed9ng t\u1ebf b\u00e0o T ho\u1eb7c th\u00fac \u0111\u1ea9y s\u1ef1 \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch.<\/li>\n<li><em>Vi\u00eam m\u00e3n t\u00ednh do kh\u1ed1i u<\/em>: C\u00e1c t\u1ebf b\u00e0o ung th\u01b0 c\u00f3 th\u1ec3 k\u00edch th\u00edch s\u1ea3n xu\u1ea5t c\u00e1c cytokine v\u00e0 chemokine g\u00e2y vi\u00eam, c\u00f3 th\u1ec3 t\u1ea1o ra m\u1ed9t m\u00f4i tr\u01b0\u1eddng th\u00fac \u0111\u1ea9y s\u1ef1 ph\u00e1t tri\u1ec3n v\u00e0 s\u1ed1ng s\u00f3t c\u1ee7a kh\u1ed1i u..<\/li>\n<li><em>S\u1ef1 m\u1ea5t \u1ed5n \u0111\u1ecbnh v\u00e0 \u0111\u1ed9t bi\u1ebfn gen:<\/em> C\u00e1c t\u1ebf b\u00e0o ung th\u01b0 c\u00f3 th\u1ec3 t\u00edch l\u0169y th\u00eam c\u00e1c \u0111\u1ed9t bi\u1ebfn v\u00e0 b\u1ea5t th\u01b0\u1eddng nhi\u1ec5m s\u1eafc th\u1ec3 theo th\u1eddi gian, d\u1eabn \u0111\u1ebfn s\u1ef1 m\u1ea5t \u1ed5n \u0111\u1ecbnh v\u00e0 kh\u00f4ng \u0111\u1ed3ng nh\u1ea5t di truy\u1ec1n v\u00e0 kh\u00f4ng \u0111\u1ed3ng nh\u1ea5t h\u01a1n n\u1eefa.<\/li>\n<\/ul>\n<ol start=\"2\">\n<li>\n<h2><strong>S\u1eed d\u1ee5ng c\u00e1c \u0111\u1eb7c t\u00ednh c\u1ee7a ung th\u01b0 l\u00e0m m\u1ee5c ti\u00eau \u0111i\u1ec1u tr\u1ecb<\/strong><\/h2>\n<p>Nhi\u1ec1u lo\u1ea1i thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong th\u1ef1c h\u00e0nh l\u00e2m s\u00e0ng c\u00f3 \u0111\u00edch t\u00e1c \u0111\u1ed9ng l\u00e0 c\u00e1c \u0111\u1eb7c t\u00ednh sinh h\u00f3a c\u1ee7a t\u1ebf b\u00e0o ung th\u01b0. C\u00e1c v\u00ed d\u1ee5 v\u1ec1 c\u00e1c lo\u1ea1i thu\u1ed1c th\u00f4ng th\u01b0\u1eddng theo c\u01a1 ch\u1ebf n\u00e0y bao g\u1ed3m:<\/li>\n<\/ol>\n<ul>\n<li><em>Ch\u1ea5t \u1ee9c ch\u1ebf t\u00edn hi\u1ec7u VEGF:<\/em> Bevacizumab, ramucirumab, aflibercept<\/li>\n<li><em>Ch\u1ea5t \u1ee9c ch\u1ebf HGF\/c-Met:<\/em> Cabozantinib, crizotinib, capmatinib<\/li>\n<li><em>T\u00e1c nh\u00e2n \u1ee9c ch\u1ebfho\u1eb7c t\u00e1i l\u1eadp tr\u00ecnh telomerase:<\/em> Imetelstat, GRN163L<\/li>\n<li><em>Ho\u1ea1t h\u00f3a mi\u1ec5n d\u1ecbch:<\/em> Ch\u1ea5t \u1ee9c ch\u1ebf \u0111i\u1ec3m ki\u1ec3m so\u00e1t (pembrolizumab, nivolumab, ipilimumab), li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o T c\u00f3 receptor chimeric antigen (CAR), ng\u01b0\u1eddi k\u00edch ho\u1ea1t t\u1ebf b\u00e0o T (blinatumomab)<\/li>\n<li><em>Ch\u1ea5t t\u00e1i ho\u1ea1t h\u00f3a p53 \u0111\u1ed9t bi\u1ebfn:<\/em> APR-246<\/li>\n<li><em>Ch\u1ea5t \u1ee9c ch\u1ebf c\u00e1c kinase ung th\u01b0:<\/em> Imatinib, dasatinib, vemurafenib<\/li>\n<li><em>Ch\u1ea5t \u1ee9c ch\u1ebf \u0111\u01b0\u1eddng ph\u00e2n k\u1ecb kh\u00ed:<\/em> 2-deoxyglucose, lonidamine<\/li>\n<li><em>Ch\u1ea5t \u1ee9c ch\u1ebf b\u1eaft ch\u01b0\u1edbc BH3:<\/em> Venetoclax, navitoclax<\/li>\n<li><em>Ch\u1ea5t \u1ee9c ch\u1ebf PARP:<\/em> Olaparib, rucaparib, niraparib<\/li>\n<\/ul>\n<figure id=\"attachment_23135\" aria-describedby=\"caption-attachment-23135\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-23135\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Screenshot-2023-04-17-141237-300x220.png\" alt=\"\" width=\"300\" height=\"220\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Screenshot-2023-04-17-141237-300x220.png 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Screenshot-2023-04-17-141237-1024x752.png 1024w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Screenshot-2023-04-17-141237-768x564.png 768w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Screenshot-2023-04-17-141237.png 1214w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-23135\" class=\"wp-caption-text\">Hallmark of Cancer- \u0110\u00edch t\u00e1c \u0111\u1ed9ng c\u1ee7a c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb ung th\u01b0 (theo Cell Press)<\/figcaption><\/figure>\n<ol start=\"3\">\n<li>\n<h2><strong>Th\u00e1ch th\u1ee9c c\u1ee7a vi\u1ec7c s\u1eed d\u1ee5ng c\u00e1c li\u1ec7u ph\u00e1p nh\u1eafm m\u1ee5c ti\u00eau \u0111\u1eb7c t\u00ednh c\u1ee7a ung th\u01b0\u00a0<\/strong><\/h2>\n<p>M\u1eb7c d\u00f9 \u0111\u00e3 c\u00f3 nh\u1eefng th\u00e0nh c\u00f4ng nh\u1ea5t \u0111\u1ecbnh c\u1ee7a chi\u1ebfn l\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb n\u00e0y, nhi\u1ec1u th\u00e1ch th\u1ee9c v\u1eabn t\u1ed3n t\u1ea1i v\u00e0 c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng t\u1edbi hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb c\u1ee7a c\u00e1c ph\u01b0\u01a1ng ph\u00e1p c\u00f3 \u0111\u00edch t\u00e1c \u0111\u1ed9ng l\u00e0 \u0111\u1eb7c t\u00ednh c\u1ee7a t\u1ebf b\u00e0o ung th\u01b0.<\/li>\n<\/ol>\n<ul>\n<li><em>T\u1ec9 l\u1ec7 t\u00e1i ph\u00e1t cao:<\/em> Do s\u1ef1 linh ho\u1ea1t c\u1ee7a kh\u1ed1i u v\u00e0 s\u1ef1 chuy\u1ec3n \u0111\u1ed5i th\u00edch nghi ph\u1ee5 thu\u1ed9c v\u00e0o c\u00e1c \u0111\u1eb7c t\u00ednh kh\u00e1c.<\/li>\n<li><em>Kh\u00e1ng thu\u1ed1c:<\/em> C\u00e1c t\u1ebf b\u00e0o ung th\u01b0 c\u00f3 th\u1ec3 k\u00edch ho\u1ea1t c\u00e1c \u0111\u01b0\u1eddng t\u00edn hi\u1ec7u thay th\u1ebf ho\u1eb7c tr\u1ea3i qua \u0111\u1ed9t bi\u1ebfn gen. \u0110i\u1ec1u n\u00e0y \u0111\u00e3 d\u1eabn \u0111\u1ebfn s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a c\u00e1c li\u1ec7u ph\u00e1p k\u1ebft h\u1ee3p m\u1ee5c ti\u00eau h\u00f3a \u0111\u1ed3ng th\u1eddi nhi\u1ec1u \u0111\u1eb7c t\u00ednh, c\u0169ng nh\u01b0 s\u1eed d\u1ee5ng ch\u1ea5t \u1ee9c ch\u1ebf \u0111i\u1ec3m ki\u1ec3m so\u00e1t mi\u1ec5n d\u1ecbch v\u00e0 li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o T c\u00f3 th\u1ee5 th\u1ec3 kh\u00e1ng nguy\u00ean d\u1ea1ng kh\u1ea3m (receptor chimeric antigen- CAR) \u0111\u1ec3 t\u1eadn d\u1ee5ng s\u1ee9c m\u1ea1nh c\u1ee7a h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch.<\/li>\n<\/ul>\n<ol start=\"4\">\n<li>\n<h2><strong>C\u00e1c khuy\u1ebfn ngh\u1ecb hi\u1ec7n c\u00f3 v\u1ec1c\u00e1c li\u1ec7u ph\u00e1p nh\u1eafm m\u1ee5c ti\u00eau<\/strong><\/h2>\n<p>M\u1ed9t s\u1ed1 t\u1ed5 ch\u1ee9c v\u00e0 c\u01a1 quan qu\u1ed1c t\u1ebf \u0111\u00e3 ph\u00e1t tri\u1ec3n c\u00e1c h\u01b0\u1edbng d\u1eabn v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng c\u00e1c li\u1ec7u ph\u00e1p c\u00f3 \u0111\u00edch t\u00e1c \u0111\u1ed9ng l\u00e0 c\u00e1c \u0111\u1eb7c t\u00ednh sinh h\u00f3a t\u1ebf b\u00e0o \u00e1c t\u00ednh trong \u0111i\u1ec1u tr\u1ecb ung th\u01b0. Nh\u1eefng h\u01b0\u1edbng d\u1eabn n\u00e0y cung c\u1ea5p th\u00f4ng tin v\u1ec1 vi\u1ec7c l\u1ef1a ch\u1ecdn b\u1ec7nh nh\u00e2n th\u00edch h\u1ee3p cho \u0111i\u1ec1u tr\u1ecb m\u1ee5c ti\u00eau h\u00f3a, s\u1ef1 k\u1ebft h\u1ee3p t\u1ed1i \u01b0u c\u1ee7a c\u00e1c li\u1ec7u ph\u00e1p v\u00e0 qu\u1ea3n l\u00fd c\u00e1c bi\u1ebfn ch\u1ee9ng li\u00ean quan \u0111\u1ebfn c\u00e1c lo\u1ea1i thu\u1ed1c n\u00e0y. C\u00e1c v\u00ed d\u1ee5 v\u1ec1 c\u00e1c h\u01b0\u1edbng d\u1eabn \u0111\u00e1ng tin c\u1eady, qu\u1ed1c t\u1ebf v\u00e0 \u0111\u01b0\u1ee3c x\u00e1c minh bao g\u1ed3m c\u00e1c h\u01b0\u1edbng d\u1eabn c\u1ee7a M\u1ea1ng L\u01b0\u1edbi Ung Th\u01b0 To\u00e0n C\u1ea7u <a href=\"https:\/\/www.nccn.org\/\">(NCCN)<\/a>, H\u1ed9i Ngh\u1ecb Y H\u1ecdc Onco Ch\u00e2u \u00c2u <a href=\"https:\/\/www.esmo.org\/\">(ESMO)<\/a> v\u00e0 H\u1ed9i Ngh\u1ecb L\u00e2m S\u00e0ng Ung th\u01b0 M\u1ef9 <a href=\"https:\/\/www.asco.org\/\">(ASCO)<\/a>.L\u00fd thuy\u1ebft c\u00e1c \u0111\u1eb7c t\u00ednh c\u1ee7a ung th\u01b0 cung c\u1ea5p m\u1ed9t khung nh\u00ecn to\u00e0n di\u1ec7n \u0111\u1ec3 hi\u1ec3u c\u00e1c c\u01a1 ch\u1ebf ph\u00e2n t\u1eed th\u00fac \u0111\u1ea9y s\u1ef1 ph\u00e1t tri\u1ec3n v\u00e0 ti\u1ebfn tri\u1ec3n c\u1ee7a ung th\u01b0. T\u01b0\u01a1ng lai c\u1ee7a \u0111i\u1ec1u tr\u1ecb ung th\u01b0 n\u1eb1m trong vi\u1ec7c ph\u00e1t tri\u1ec3n c\u00e1c li\u1ec7u ph\u00e1p k\u1ebft h\u1ee3p m\u1ee5c ti\u00eau h\u00f3a \u0111\u1ed3ng th\u1eddi nhi\u1ec1u \u0111\u1eb7c t\u00ednh v\u00e0 t\u1eadn d\u1ee5ng s\u1ee9c m\u1ea1nh c\u1ee7a h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch \u0111\u1ec3 lo\u1ea1i b\u1ecf c\u00e1c t\u1ebf b\u00e0o ung th\u01b0.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Ung th\u01b0 l\u00e0 m\u1ed9t c\u0103n b\u1ec7nh ph\u1ee9c t\u1ea1p li\u00ean quan \u0111\u1ebfn nhi\u1ec1u qu\u00e1 tr\u00ecnh sinh h\u1ecdc, bao g\u1ed3m vi\u1ec7c t\u00edch l\u0169y m\u1ed9t s\u1ed1 \u0111\u1eb7c t\u00ednh c\u1ee7a t\u1ebf b\u00e0o ung th\u01b0 (hallmarks of cancer). N\u0103m 2000, Douglas Hanahan v\u00e0 Robert Weinberg \u0111\u1ec1 xu\u1ea5t m\u1ed9t l\u00fd thuy\u1ebft \u0111\u1ec3 mi\u00eau t\u1ea3 nh\u1eefng \u0111\u1eb7c t\u00ednh c\u1ee7a ung th\u01b0, bao [&hellip;]<\/p>\n","protected":false},"author":47,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[6,33],"tags":[3],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>10 \u0110\u1eb7c T\u00ednh C\u1ee7a Ung Th\u01b0- \u1ee8ng D\u1ee5ng Trong \u0110i\u1ec1u Tr\u1ecb<\/title>\n<meta name=\"description\" content=\"L\u00fd thuy\u1ebft c\u00e1c \u0111\u1eb7c t\u00ednh c\u1ee7a ung th\u01b0 (hallmark of cancer) cung c\u1ea5p n\u1ec1n t\u1ea3ng \u0111\u1ec3 hi\u1ec3u c\u00e1c c\u01a1 ch\u1ebf ph\u00e2n t\u1eed v\u00e0 m\u1ee5c ti\u00eau \u0111i\u1ec1u tr\u1ecb ti\u1ec1m n\u0103ng.\" \/>\n<meta name=\"robots\" content=\"noindex, 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