{"id":21727,"date":"2023-04-16T11:46:35","date_gmt":"2023-04-16T04:46:35","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=21727"},"modified":"2023-04-17T12:54:43","modified_gmt":"2023-04-17T05:54:43","slug":"dung-dich-bom-rua-chlorhexidine-gluconate-chx","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/16\/dung-dich-bom-rua-chlorhexidine-gluconate-chx\/","title":{"rendered":"Dung d\u1ecbch b\u01a1m r\u1eeda: Chlorhexidine Gluconate (CHX)"},"content":{"rendered":"

Chlorhexidine gluconate (CHX) l\u00e0 m\u1ed9t trong nh\u1eefng dung d\u1ecbch b\u01a1m \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb n\u1ed9i nha, v\u1edbi t\u00e1c d\u1ee5ng kh\u00e1ng khu\u1ea9n m\u1ea1nh v\u1edbi c\u00e1c vi khu\u1ea9n gram d\u01b0\u01a1ng, gram \u00e2m v\u00e0 c\u1ea3 n\u1ea5m men. B\u00e0i vi\u1ebft n\u00e0y s\u1ebd cung c\u1ea5p nh\u1eefng ki\u1ebfn th\u1ee9c v\u1ec1 c\u01a1 ch\u1ebf c\u0169ng nh\u01b0 \u1ee9ng d\u1ee5ng trong l\u00e2m s\u00e0ng c\u1ee7a dung d\u1ecbch b\u01a1m r\u1eeda n\u00e0y, gi\u00fap c\u00e1c b\u00e1c s\u0129 R\u0103ng H\u00e0m M\u1eb7t th\u1ef1c h\u00e0nh n\u1ed9i nha \u0111\u1ea1t k\u1ebft qu\u1ea3 t\u1ed1i \u01b0u.<\/strong><\/p>\n

\"chlorhexidine-bom-rua\"
Chlorhexidine gluconate \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 m\u1ed9t dung d\u1ecbch b\u01a1m r\u1eeda trong \u0111i\u1ec1u tr\u1ecb n\u1ed9i nha<\/figcaption><\/figure>\n

1. C\u1ea5u tr\u00fac ph\u00e2n t\u1eed<\/strong><\/h2>\n

CHX l\u00e0 m\u1ed9t ph\u00e2n t\u1eed m\u1ea1nh v\u1edbi pH \u1edf m\u1ee9c gi\u1eefa 5,5 v\u00e0 7, thu\u1ed9c nh\u00f3m polybiguanide v\u00e0 bao g\u1ed3m hai v\u00f2ng fourclophenyl \u0111\u1ed1i x\u1ee9ng v\u00e0 hai nh\u00f3m biguanide \u0111\u01b0\u1ee3c k\u1ebft n\u1ed1i b\u1edfi m\u1ed9t chu\u1ed7i hexamethylene trung t\u00e2m.<\/p>\n

Mu\u1ed1i digluconate c\u1ee7a CHX d\u1ec5 tan trong n\u01b0\u1edbc v\u00e0 r\u1ea5t \u1ed5n \u0111\u1ecbnh<\/p>\n

2. C\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng<\/strong><\/h2>\n

Do t\u00ednh mang \u0111i\u1ec7n d\u01b0\u01a1ng (cationic) c\u1ee7a n\u00f3, Chlorhexidine c\u00f3 kh\u1ea3 n\u0103ng k\u1ebft d\u00ednh \u0111i\u1ec7n t\u0129nh v\u00e0o c\u00e1c b\u1ec1 m\u1eb7t mang \u0111i\u1ec7n t\u00edch \u00e2m c\u1ee7a vi khu\u1ea9n, g\u00e2y t\u1ed5n th\u01b0\u01a1ng l\u1edbp v\u1ecf ngo\u00e0i c\u1ee7a vi khu\u1ea9n. CHX l\u00e0 m\u1ed9t ch\u1ea5t kh\u00e1ng khu\u1ea9n ph\u1ed5 r\u1ed9ng, ho\u1ea1t \u0111\u1ed9ng ch\u1ed1ng l\u1ea1i vi khu\u1ea9n gram d\u01b0\u01a1ng v\u00e0 gram \u00e2m c\u0169ng nh\u01b0 c\u00e1c lo\u1ea1i n\u1ea5m men.<\/p>\n

T\u00f9y thu\u1ed9c v\u00e0o n\u1ed3ng \u0111\u1ed9, CHX c\u00f3 th\u1ec3 c\u00f3 t\u00e1c d\u1ee5ng ki\u1ec1m khu\u1ea9n v\u00e0 s\u00e1t khu\u1ea9n. \u1ede n\u1ed3ng \u0111\u1ed9 cao, CHX ho\u1ea1t \u0111\u1ed9ng nh\u01b0 m\u1ed9t ch\u1ea5t t\u1ea9y v\u00e0 t\u00e1c \u0111\u1ed9ng s\u00e1t khu\u1ea9n b\u1eb1ng c\u00e1ch g\u00e2y t\u1ed5n th\u01b0\u01a1ng m\u00e0ng t\u1ebf b\u00e0o v\u00e0 g\u00e2y k\u1ebft t\u1ee7a t\u1ebf b\u00e0o ch\u1ea5t. \u1ede n\u1ed3ng \u0111\u1ed9 th\u1ea5p, CHX l\u00e0 ch\u1ea5t k\u00ecm khu\u1ea9n, g\u00e2y r\u00f2 r\u1ec9 c\u00e1c ch\u1ea5t v\u1edbi kh\u1ed1i l\u01b0\u1ee3ng ph\u00e2n t\u1eed th\u1ea5p (v\u00ed d\u1ee5: kali v\u00e0 photpho) t\u1eeb m\u00e0ng t\u1ebf b\u00e0o m\u00e0 kh\u00f4ng l\u00e0m t\u1ed5n th\u01b0\u01a1ng t\u1ebf b\u00e0o v\u0129nh vi\u1ec5n.<\/p>\n

3. T\u00ednh kh\u00e1ng khu\u1ea9n b\u1ec1n v\u1eefng c\u1ee7a Chlorhexidine gluconate<\/strong><\/h2>\n

Do t\u00ednh cationic c\u1ee7a ph\u00e2n t\u1eed CHX, n\u00f3 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c h\u1ea5p th\u1ee5 b\u1edfi c\u00e1c ch\u1ea5t ph\u00e2n t\u1eed \u00e2m \u0111i\u1ec7n nh\u01b0 ni\u00eam m\u1ea1c mi\u1ec7ng v\u00e0 c\u1ea5u tr\u00fac r\u0103ng. CHX d\u1ec5 d\u00e0ng h\u1ea5p th\u1ee5 tr\u00ean hydroxyapatite v\u00e0 r\u0103ng. C\u00e1c nghi\u00ean c\u1ee9u \u0111\u00e3 ch\u1ec9 ra r\u1eb1ng qu\u00e1 tr\u00ecnh h\u1ea5p th\u1ee5 CHX tr\u00ean r\u0103ng l\u00e0 qu\u00e1 tr\u00ecnh c\u00f3 th\u1ec3 \u0111\u1ea3o ng\u01b0\u1ee3c. Qu\u00e1 tr\u00ecnh h\u1ea5p th\u1ee5 v\u00e0 gi\u1ea3i ph\u00f3ng CHX n\u00e0y d\u1eabn \u0111\u1ebfn ho\u1ea1t t\u00ednh \u201ckh\u00e1ng khu\u1ea9n b\u1ec1n v\u1eefng\u201d c\u1ee7a n\u00f3. Hi\u1ec7u \u1ee9ng n\u00e0y ph\u1ee5 thu\u1ed9c v\u00e0o n\u1ed3ng \u0111\u1ed9 CHX, \u1edf n\u1ed3ng \u0111\u1ed9 th\u1ea5p t\u1eeb 0,005% \u0111\u1ebfn 0,01%, ch\u1ec9 c\u00f3 m\u1ed9t l\u1edbp m\u1ecfng CHX \u0111\u01b0\u1ee3c h\u1ea5p th\u1ee5 tr\u00ean b\u1ec1 m\u1eb7t r\u0103ng, nh\u01b0ng \u1edf n\u1ed3ng \u0111\u1ed9 cao h\u01a1n, nhi\u1ec1u l\u1edbp CHX \u0111\u01b0\u1ee3c h\u00ecnh th\u00e0nh tr\u00ean b\u1ec1 m\u1eb7t, cung c\u1ea5p m\u1ed9t b\u1ec3 ch\u1ee9a CHX c\u00f3 th\u1ec3 gi\u1ea3i ph\u00f3ng th\u00eam nhanh ch\u00f3ng v\u00e0o m\u00f4i tr\u01b0\u1eddng khi n\u1ed3ng \u0111\u1ed9 CHX trong m\u00f4i tr\u01b0\u1eddng xung quanh gi\u1ea3m. Th\u1eddi gian v\u00e0 n\u1ed3ng \u0111\u1ed9 CHX c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng kh\u00e1ng khu\u1ea9n b\u1ec1n v\u1eefng. \u00a0M\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u \u0111\u00e3 ch\u1ec9 ra r\u1eb1ng CHX 4% c\u00f3 kh\u1ea3 n\u0103ng kh\u00e1ng khu\u1ea9n b\u1ec1n v\u1eefng l\u1edbn h\u01a1n 0,2% sau 5 ph\u00fat s\u1eed d\u1ee5ng. M\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u kh\u00e1c cho bi\u1ebft CHX c\u1ea7n \u0111\u01b0\u1ee3c \u0111\u1ec3 l\u1ea1i tr\u00ean 1 gi\u1edd trong \u1ed1ng t\u1ee7y \u0111\u1ec3 \u0111\u01b0\u1ee3c h\u1ea5p th\u1ee5 b\u1edfi m\u00f4 ng\u00e0. Tuy nhi\u00ean, v\u00ec c\u00e1c k\u1ebft lu\u1eadn v\u1ec1 t\u00ednh kh\u00e1ng khu\u1ea9n b\u1ec1n v\u1eefng v\u00e0 th\u1eddi gian n\u00ean s\u1eed d\u1ee5ng CHX c\u00f2n l\u00e0 v\u1ea5n \u0111\u1ec1 \u0111ang \u0111\u01b0\u1ee3c tranh lu\u1eadn.<\/p>\n

4. Chlorhexidine gluconate nh\u01b0 m\u1ed9t dung d\u1ecbch b\u01a1m r\u1eeda n\u1ed9i nha<\/strong><\/h2>\n

S\u1eed d\u1ee5ng Chlorhexidine nh\u01b0 m\u1ed9t dung d\u1ecbch b\u01a1m r\u1eeda \u1ed1ng t\u1ee7y v\u00e0 thu\u1ed1c \u0111\u1eb7t t\u1ee7y \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u r\u1ed9ng r\u00e3i c\u1ea3 trong nghi\u00ean c\u1ee9u in vivo v\u00e0 in vitro. Hi\u1ec7u qu\u1ea3 kh\u00e1ng khu\u1ea9n c\u1ee7a CHX nh\u01b0 m\u1ed9t dung d\u1ecbch b\u01a1m r\u1eeda \u00a0ph\u1ee5 thu\u1ed9c v\u00e0o n\u1ed3ng \u0111\u1ed9 c\u1ee7a n\u00f3. CHX 2% \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh c\u00f3 hi\u1ec7u qu\u1ea3 kh\u00e1ng khu\u1ea9n t\u1ed1t h\u01a1n 0,12% CHX trong nghi\u00ean c\u1ee9u in vitro. Khi so s\u00e1nh v\u1edbi NaOCl, NaOCl c\u00f3 l\u1ee3i th\u1ebf r\u00f5 r\u00e0ng h\u01a1n CHX v\u1ec1 kh\u1ea3 n\u0103ng h\u00f2a tan ch\u1ea5t h\u1eefu c\u01a1 m\u00e0 CHX thi\u1ebfu; do \u0111\u00f3, m\u1eb7c d\u00f9 c\u00e1c nghi\u00ean c\u1ee9u in vitro cho th\u1ea5y m\u1ed9t s\u1ed1 l\u1ee3i th\u1ebf khi s\u1eed d\u1ee5ng CHX, nh\u01b0ng trong tr\u01b0\u1eddng h\u1ee3p c\u00f3 m\u00f4 h\u1eefu c\u01a1, NaOCl r\u00f5 r\u00e0ng \u0111\u01b0\u1ee3c \u01b0u ti\u00ean h\u01a1n.<\/p>\n

Hi\u1ec7u qu\u1ea3 kh\u00e1ng khu\u1ea9n c\u1ee7a CHX trong c\u00e1c \u1ed1ng t\u1ee7y r\u0103ng nhi\u1ec5m tr\u00f9ng \u0111\u00e3 \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u trong nhi\u1ec1u nghi\u00ean c\u1ee9u in vivo. Nhi\u1ec1u nghi\u00ean c\u1ee9u cho r\u1eb1ng b\u01a1m r\u1eeda trong 30 ph\u00fat v\u1edbi 2,5% NaOCl hi\u1ec7u qu\u1ea3 h\u01a1n \u0111\u00e1ng k\u1ec3 so v\u1edbi 0,2% CHX \u1edf tr\u01b0\u1eddng h\u1ee3p t\u1ee7y r\u0103ng nhi\u1ec5m tr\u00f9ng.<\/p>\n

Trong m\u1ed9t nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng \u0111\u01b0\u1ee3c ki\u1ec3m so\u00e1t v\u00e0 ng\u1eabu nhi\u00ean, hi\u1ec7u qu\u1ea3 c\u1ee7a dung d\u1ecbch 2% CHX \u0111\u01b0\u1ee3c th\u1eed nghi\u1ec7m so v\u1edbi n\u01b0\u1edbc mu\u1ed1i sinh l\u00fd b\u1eb1ng k\u1ef9 thu\u1eadt c\u1ea5y vi khu\u1ea9n. T\u1ea5t c\u1ea3 c\u00e1c r\u0103ng \u0111\u1ec1u \u0111\u01b0\u1ee3c \u00a0t\u1ea1o h\u00ecnh \u1ed1ng t\u1ee7y v\u00e0 b\u01a1m r\u1eeda b\u1eb1ng NaOCl 1%. Sau \u0111\u00f3, dung d\u1ecbch 2% CHX ho\u1eb7c n\u01b0\u1edbc mu\u1ed1i \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng l\u00e0m dung d\u1ecbch b\u01a1m r\u1eeda cu\u1ed1i c\u00f9ng. T\u00e1c gi\u1ea3 b\u00e1o c\u00e1o m\u1ed9t s\u1ef1 gi\u1ea3m \u0111\u00e1ng k\u1ec3 trong t\u1ef7 l\u1ec7 vi khu\u1ea9n d\u01b0\u01a1ng t\u00ednh \u1edf nh\u00f3m CHX. K\u1ebft qu\u1ea3 c\u1ee7a h\u1ecd cho th\u1ea5y c\u00e1ch b\u01a1m r\u1eeda \u1ed1ng t\u1ee7y r\u0103ng s\u1eed d\u1ee5ng CHX l\u00e0 dung d\u1ecbch cu\u1ed1i t\u1ed1t h\u01a1n so v\u1edbi n\u01b0\u1edbc mu\u1ed1i sinh l\u00fd.<\/p>\n

Trong c\u00e1c nghi\u00ean c\u1ee9u g\u1ea7n \u0111\u00e2y, hi\u1ec7u qu\u1ea3 kh\u00e1ng khu\u1ea9n c\u1ee7a gel CHX 2% \u0111\u01b0\u1ee3c th\u1eed nghi\u1ec7m so v\u1edbi NaOCl 2,5% trong r\u0103ng b\u1ecb vi\u00eam quanh ch\u00f3p, v\u1edbi l\u01b0\u1ee3ng vi khu\u1ea9n \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 b\u1eb1ng k\u1ef9 thu\u1eadt ph\u1ea3n \u1ee9ng chu\u1ed7i polymerase th\u1eddi gian th\u1ef1c (RTQ-PCR). S\u1ef1 gi\u1ea3m vi khu\u1ea9n trong nh\u00f3m NaOCl l\u1edbn h\u01a1n \u0111\u00e1ng k\u1ec3 so v\u1edbi nh\u00f3m CHX khi \u0111\u01b0\u1ee3c \u0111o b\u1eb1ng RTQ- PCR. D\u1ef1a tr\u00ean k\u1ef9 thu\u1eadt c\u1ea5y vi khu\u1ea9n, s\u1ef1 ph\u00e1t tri\u1ec3n vi khu\u1ea9n \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n \u1edf 50% s\u1ed1 m\u1eabu trong nh\u00f3m CHX so v\u1edbi 25% trong nh\u00f3m NaOCl.<\/p>\n

Kh\u00e1c v\u1edbi NaOCl, CHX kh\u00f4ng c\u00f3 t\u00ednh ch\u1ea5t h\u00f2a tan m\u00f4. Do \u0111\u00f3, NaOCl v\u1eabn \u0111\u01b0\u1ee3c coi l\u00e0 dung d\u1ecbch t\u1ea9y tr\u00f9ng ch\u00ednh trong \u0111i\u1ec1u tr\u1ecb t\u1ee7y r\u0103ng.<\/p>\n

5. Ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng v\u1edbi Chlorhexidine gluconate<\/strong><\/h2>\n

Ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng v\u1edbi CHX l\u00e0 hi\u1ebfm g\u1eb7p trong c\u00e1c \u0111i\u1ec1u tr\u1ecb n\u1ed9i nha. Tuy nhi\u00ean, m\u1ed9t s\u1ed1 ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng nh\u01b0 ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng c\u1ea5p t\u00ednh, vi\u00eam da ti\u1ebfp x\u00fac v\u00e0 ph\u00e1t ban m\u1ec1 \u0111ay \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o sau ti\u1ebfp x\u00fac tr\u1ef1c ti\u1ebfp v\u1edbi m\u00f4 ni\u00eam m\u1ea1c ho\u1eb7c v\u1ebft th\u01b0\u01a1ng m\u1edf.<\/p>\n

6. H\u1ea1n ch\u1ebf<\/strong><\/h2>\n

H\u1ea1n ch\u1ebf c\u1ee7a vi\u1ec7c s\u1eed d\u1ee5ng dung d\u1ecbch b\u01a1m r\u1eeda CHX nh\u01b0 m\u1ed9t dung d\u1ecbch ch\u00ednh v\u00e0 duy nh\u1ea5t trong \u0111i\u1ec1u tr\u1ecb t\u1ee7y r\u0103ng l\u00e0 kh\u00f4ng th\u1ec3. B\u1edfi CHX kh\u00f4ng c\u00f3 kh\u1ea3 n\u0103ng tan ch\u1ea5t h\u1eefu c\u01a1, kh\u00f4ng t\u00e1c \u0111\u1ed9ng l\u00ean l\u1edbp \u201csmear layer\u201d v\u00e0 ch\u1ec9 c\u00f3 \u1ea3nh h\u01b0\u1edfng nh\u1ecf \u0111\u1ebfn vi\u1ec7c ph\u00e1 b\u1ecf l\u1edbp m\u00e0ng biofilm.<\/p>\n

T\u01b0\u01a1ng t\u00e1c gi\u1eefa CHX v\u00e0 EDTA: S\u1ef1 k\u1ebft h\u1ee3p gi\u1eefa CHX v\u00e0 EDTA t\u1ea1o ra m\u1ed9t k\u1ebft t\u1ee7a tr\u1eafng.<\/p>\n

7. Khuy\u1ebfn ngh\u1ecb l\u00e2m s\u00e0ng<\/strong><\/h2>\n

Khuy\u1ebfn ngh\u1ecb l\u00e2m s\u00e0ng \u0111\u1ec3 s\u1eed d\u1ee5ng CHX trong \u0111i\u1ec1u tr\u1ecb t\u1ee7y r\u0103ng:<\/p>\n

– Trong nh\u1eefng tr\u01b0\u1eddng h\u1ee3p r\u0103ng ch\u00f3p m\u1edf ho\u1eb7c th\u1ee7ng th\u00e0nh, tr\u01b0\u1eddng h\u1ee3p c\u00f3 nguy c\u01a1 \u0111\u01b0a NaOCl ra qu\u00e1 ch\u00f3p.<\/p>\n

– S\u1eed d\u1ee5ng \u0111\u1ec3 b\u01a1m r\u1eeda l\u1ea7n cu\u1ed1i c\u00f9ng \u0111\u1ec3 ti\u1ebfp t\u1ee5c t\u0103ng c\u01b0\u1eddng kh\u1eed tr\u00f9ng v\u00e0 c\u1ea3i thi\u1ec7n k\u1ebft d\u00ednh m\u00f4 ng\u00e0 (n\u1ebfu c\u1ea7n)<\/p>\n

Ngu\u1ed3n tham kh\u1ea3o<\/em><\/p>\n

1. Barbosa CA, Goncalves RB, Siqueira Jr JF, De Uzeda; <\/span>M. Evaluation of the antibacterial activities of calcium hydroxide, chlorhexidine, and camphorated <\/span>paramonochlorophenol as intracanal medicament. A <\/span>clinical and laboratory study. J Endod. 1997;23. <\/span>297\u2013300.<\/span><\/em><\/p>\n

2. Basrani B. Irrigation in endodontic treatment. Alpha Omegan. 2011 Spring;104(1-2):18-25. PMID: 21905363.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

Chlorhexidine gluconate (CHX) l\u00e0 m\u1ed9t trong nh\u1eefng dung d\u1ecbch b\u01a1m \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb n\u1ed9i nha, v\u1edbi t\u00e1c d\u1ee5ng kh\u00e1ng khu\u1ea9n m\u1ea1nh v\u1edbi c\u00e1c vi khu\u1ea9n gram d\u01b0\u01a1ng, gram \u00e2m v\u00e0 c\u1ea3 n\u1ea5m men. B\u00e0i vi\u1ebft n\u00e0y s\u1ebd cung c\u1ea5p nh\u1eefng ki\u1ebfn th\u1ee9c v\u1ec1 c\u01a1 ch\u1ebf c\u0169ng nh\u01b0 \u1ee9ng d\u1ee5ng trong l\u00e2m s\u00e0ng […]<\/p>\n","protected":false},"author":35,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[28,33],"tags":[3],"yoast_head":"\nDung d\u1ecbch b\u01a1m r\u1eeda: Chlorhexidine Gluconate (CHX) - Vinmec<\/title>\n<meta name=\"description\" content=\"B\u00e0i vi\u1ebft n\u00e0y s\u1ebd cung c\u1ea5p nh\u1eefng ki\u1ebfn th\u1ee9c v\u1ec1 c\u01a1 ch\u1ebf c\u0169ng nh\u01b0 \u1ee9ng d\u1ee5ng trong l\u00e2m s\u00e0ng chlorhexidine gluconate trong \u0111i\u1ec1u tr\u1ecb n\u1ed9i nha.\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Dung d\u1ecbch b\u01a1m r\u1eeda: Chlorhexidine Gluconate (CHX) - 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