{"id":21226,"date":"2023-04-16T11:46:00","date_gmt":"2023-04-16T04:46:00","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=21226"},"modified":"2023-04-17T12:55:03","modified_gmt":"2023-04-17T05:55:03","slug":"dung-dich-bom-rua-edta","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/16\/dung-dich-bom-rua-edta\/","title":{"rendered":"Dung d\u1ecbch b\u01a1m r\u1eeda: Ethylene Diamine Tetraacetic Acid (EDTA)"},"content":{"rendered":"

Ethylenediaminetetraacetic acid (EDTA) l\u00e0 m\u1ed9t trong nh\u1eefng dung d\u1ecbch b\u01a1m r\u1eeda ph\u1ed5 bi\u1ebfn trong \u0111i\u1ec1u tr\u1ecb n\u1ed9i nha, v\u1edbi t\u00e1c d\u1ee5ng h\u00f2a tan m\u00f4 kho\u00e1ng h\u00f3a v\u00e0 c\u00e1c m\u1ea3nh v\u1ee5n ng\u00e0 trong \u1ed1ng t\u1ee7y. B\u00e0i vi\u1ebft n\u00e0y s\u1ebd cung c\u1ea5p nh\u1eefng ki\u1ebfn th\u1ee9c v\u1ec1 c\u01a1 ch\u1ebf c\u0169ng nh\u01b0 \u1ee9ng d\u1ee5ng trong l\u00e2m s\u00e0ng c\u1ee7a dung d\u1ecbch b\u01a1m r\u1eeda n\u00e0y, gi\u00fap c\u00e1c b\u00e1c s\u0129 R\u0103ng H\u00e0m M\u1eb7t th\u1ef1c h\u00e0nh n\u1ed9i nha \u0111\u1ea1t k\u1ebft qu\u1ea3 t\u1ed1i \u01b0u.<\/strong><\/p>\n

\"edta-bom-rua\"
EDTA l\u00e0 m\u1ed9t dung d\u1ecbch b\u01a1m r\u1eeda quan tr\u1ecdng trong \u0111i\u1ec1u tr\u1ecb n\u1ed9i nha<\/figcaption><\/figure>\n
    \n
  1. \n

    T\u1ed5ng quan v\u1ec1 EDTA<\/h2>\n<\/li>\n<\/ol>\n

    Ethylenediaminetetraacetic acid, vi\u1ebft t\u1eaft l\u00e0 EDTA, l\u00e0 m\u1ed9t axit aminopolycarboxylic, l\u00e0 ch\u1ea5t r\u1eafn kh\u00f4ng m\u00e0u tan trong n\u01b0\u1edbc. EDTA th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 m\u1ed9t dung d\u1ecbch b\u01a1m r\u1eeda v\u00ec n\u00f3 c\u00f3 kh\u1ea3 n\u0103ng chelate-h\u00f3a v\u00e0 lo\u1ea1i b\u1ecf ph\u1ea7n kho\u00e1ng c\u1ee7a l\u1edbp \u201csmear layer\u201d tr\u00ean ng\u00e0 r\u0103ng.<\/p>\n

    \u0110\u00e2y l\u00e0 m\u1ed9t axit polyaminocarboxylic c\u00f3 c\u00f4ng th\u1ee9c [CH2N(CH2CO2H)2]2. \u0110i\u1ec3m n\u1ed5i b\u1eadt c\u1ee7a n\u00f3 nh\u01b0 m\u1ed9t ch\u1ea5t chelate l\u00e0 do kh\u1ea3 n\u0103ng k\u1ebft h\u1ee3p c\u00e1c ion kim lo\u1ea1i c\u00f3 \u0111i\u1ec7n t\u00edch hai ho\u1eb7c ba nh\u01b0 Ca2+ v\u00e0 Fe3+. Sau khi k\u1ebft h\u1ee3p v\u1edbi EDTA, c\u00e1c ion kim lo\u1ea1i v\u1eabn c\u00f2n \u1edf trong dung d\u1ecbch nh\u01b0ng c\u00f3 t\u00ednh t\u00e1c d\u1ee5ng gi\u1ea3m \u0111i.<\/p>\n

      \n
    1. \n

      L\u1ecbch s\u1eed s\u1eed d\u1ee5ng EDTA nh\u01b0 m\u1ed9t dung d\u1ecbch b\u01a1m r\u1eeda<\/h2>\n<\/li>\n<\/ol>\n

      H\u1ee3p ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c m\u00f4 t\u1ea3 l\u1ea7n \u0111\u1ea7u ti\u00ean v\u00e0o n\u0103m 1935 b\u1edfi Ferdinand Munz, ng\u01b0\u1eddi \u0111\u00e3 t\u1ed5ng h\u1ee3p h\u1ee3p ch\u1ea5t t\u1eeb ethylenediamine v\u00e0 axit chloroacetic. Ch\u1ea5t chelate \u0111\u01b0\u1ee3c gi\u1edbi thi\u1ec7u v\u00e0o l\u0129nh v\u1ef1c nha khoa \u0111\u1ec3 h\u1ed7 tr\u1ee3 cho vi\u1ec7c chu\u1ea9n b\u1ecb c\u00e1c \u1ed1ng t\u1ee7y h\u1eb9p v\u00e0 v\u00f4i h\u00f3a v\u00e0o n\u0103m 1957 b\u1edfi Nygaard-\u00d8stby. Hi\u1ec7n nay, EDTA ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c t\u1ed5ng h\u1ee3p t\u1eeb ethylenediamine (1,2-diaminoethane), formaldehyde (methanal) v\u00e0 sodium cyanide.<\/p>\n

        \n
      1. \n

        C\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng c\u1ee7a EDTA<\/h2>\n<\/li>\n<\/ol>\n

        Khi ti\u1ebfp x\u00fac tr\u1ef1c ti\u1ebfp trong m\u1ed9t kho\u1ea3ng th\u1eddi gian d\u00e0i, EDTA lo\u1ea1i b\u1ecf c\u00e1c protein b\u1ec1 m\u1eb7t vi khu\u1ea9n b\u1eb1ng c\u00e1ch k\u1ebft h\u1ee3p v\u1edbi c\u00e1c ion kim lo\u1ea1i t\u1eeb m\u00e0ng t\u1ebf b\u00e0o, \u0111i\u1ec1u n\u00e0y cu\u1ed1i c\u00f9ng d\u1eabn \u0111\u1ebfn s\u1ef1 ch\u1ebft c\u1ee7a vi khu\u1ea9n.<\/p>\n

        Nh\u01b0 c\u00e1c ch\u1ea5t chelate kh\u00e1c, EDTA t\u1ea1o th\u00e0nh m\u1ed9t ph\u1ee9c ch\u1ea5t \u1ed5n \u0111\u1ecbnh v\u1edbi canxi. Khi t\u1ea5t c\u1ea3 c\u00e1c ion c\u00f3 s\u1eb5n \u0111\u00e3 \u0111\u01b0\u1ee3c k\u1ebft h\u1ee3p, s\u1ef1 c\u00e2n b\u1eb1ng \u0111\u01b0\u1ee3c thi\u1ebft l\u1eadp v\u00e0 kh\u00f4ng c\u00f3 s\u1ef1 h\u00f2a tan ra n\u00e0o x\u1ea3y ra th\u00eam n\u1eefa; do \u0111\u00f3, EDTA t\u1ef1 h\u1ea1n ch\u1ebf s\u1ef1 ho\u1ea1t \u0111\u1ed9ng c\u1ee7a ch\u00ednh m\u00ecnh.<\/p>\n

          \n
        1. \n

          \u1ee8ng d\u1ee5ng c\u1ee7a EDTA trong \u0111i\u1ec1u tr\u1ecb n\u1ed9i nha<\/h2>\n<\/li>\n<\/ol>\n

          Vi\u1ec7c l\u00e0m s\u1ea1ch ho\u00e0n ch\u1ec9nh c\u1ee7a h\u1ec7 th\u1ed1ng \u1ed1ng t\u1ee7y y\u00eau c\u1ea7u s\u1ef1 k\u1ebft h\u1ee3p c\u00e1c dung d\u1ecbch b\u01a1m r\u1eeda h\u00f2a tan m\u00f4 h\u1eefu c\u01a1 v\u00e0 v\u00f4 c\u01a1. V\u00ec NaOCl ch\u1ec9 c\u00f3 t\u00e1c d\u1ee5ng h\u00f2a tan m\u00f4 h\u1eefu c\u01a1, c\u00e1c dung d\u1ecbch kh\u00e1c n\u00ean \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 lo\u1ea1i b\u1ecf l\u1edbp v\u00f4i hay m\u00f4 v\u00f4 c\u01a1 tr\u00ean b\u1ec1 m\u1eb7t \u201csmear layer\u201d v\u00e0 m\u1ea3nh v\u1ee5n ng\u00e0 trong h\u1ec7 th\u1ed1ng \u1ed1ng t\u1ee7y. S\u1eed d\u1ee5ng c\u00e1c ch\u1ea5t h\u1ee7y kho\u00e1ng, nh\u01b0 EDTA v\u00e0 CA, v\u1edbi vai tr\u00f2 l\u00e0 c\u00e1c dung d\u1ecbch ph\u1ee5 tr\u1ee3 trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb t\u1ee7y \u0111\u01b0\u1ee3c khuy\u1ebfn ngh\u1ecb. Dung d\u1ecbch EDTA \u0111\u1ea7u ti\u00ean \u0111\u01b0\u1ee3c khuy\u1ebfn ngh\u1ecb c\u00f3 n\u1ed3ng \u0111\u1ed9 15% v\u00e0 pH 7,3.<\/p>\n

          Hi\u1ec7n nay, EDTA \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng ph\u1ed5 bi\u1ebfn nh\u1ea5t d\u01b0\u1edbi d\u1ea1ng dung d\u1ecbch \u0111\u00e3 trung h\u00f2a 17%. Dung d\u1ecbch ph\u1ea3n \u1ee9ng v\u1edbi c\u00e1c ion canxi trong m\u00f4 ng\u00e0 v\u00e0 t\u1ea1o th\u00e0nh c\u00e1c ph\u1ee9c ch\u1ea5t canxi-chelate tan trong n\u01b0\u1edbc. Qu\u00e1 tr\u00ecnh h\u1ee7y canxi \u1edf m\u00f4 ng\u00e0 l\u00e0 m\u1ed9t qu\u00e1 tr\u00ecnh t\u1ef1 h\u1ea1n ch\u1ebf v\u00e0 cu\u1ed1i c\u00f9ng s\u1ebd d\u1eebng l\u1ea1i do thi\u1ebfu l\u01b0\u1ee3ng ch\u1ea5t chelate c\u00f3 th\u1ec3 ph\u1ea3n \u1ee9ng \u0111\u1ee7 nhanh.<\/p>\n

          M\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u \u0111\u00e3 ch\u1ec9 ra r\u1eb1ng b\u01a1m r\u1eeda 10 ml dung d\u1ecbch EDTA 17% trong 1 ph\u00fat hi\u1ec7u qu\u1ea3 lo\u1ea1i b\u1ecf l\u1edbp \u201csmear layer\u201d tr\u00ean th\u00e0nh \u1ed1ng t\u1ee7y. H\u1ecd quan s\u00e1t th\u1ea5y r\u1eb1ng s\u1ef1 h\u1ee7y kho\u00e1ng c\u1ee7a m\u00f4 ng\u00e0 t\u0103ng d\u1ea7n t\u1ec9 l\u1ec7 thu\u1eadn theo th\u1eddi gian ti\u1ebfp x\u00fac, n\u1ed3ng \u0111\u1ed9 EDTA (t\u1eeb 10% \u0111\u1ebfn 17%), v\u00e0 pH (t\u1eeb 7,5 \u0111\u1ebfn 9).<\/p>\n

          Vi\u1ec7c s\u1eed d\u1ee5ng si\u00eau \u00e2m \u00e1p d\u1ee5ng dung d\u1ecbch EDTA 17% trong 1 ph\u00fat r\u1ea5t hi\u1ec7u qu\u1ea3 \u0111\u1ec3 lo\u1ea1i b\u1ecf l\u1edbp \u201csmear layer\u201d tr\u00ean b\u1ec1 m\u1eb7t th\u00e0nh \u1ed1ng t\u1ee7y, \u0111\u1eb7c bi\u1ec7t l\u00e0 \u1edf ph\u1ea7n ba ch\u00f3p r\u0103ng, v\u00e0 s\u1eed d\u1ee5ng li\u00ean t\u1ee5c dung d\u1ecbch EDTA trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb t\u1ee7y c\u0169ng \u0111\u01b0\u1ee3c khuy\u1ebfn kh\u00edch.<\/p>\n

          M\u1eb7c d\u00f9 axit citric c\u00f3 v\u1ebb m\u1ea1nh h\u01a1n m\u1ed9t ch\u00fat \u1edf n\u1ed3ng \u0111\u1ed9 t\u01b0\u01a1ng t\u1ef1 so v\u1edbi EDTA, c\u1ea3 hai ch\u1ea5t \u0111\u1ec1u cho th\u1ea5y hi\u1ec7u qu\u1ea3 cao trong vi\u1ec7c lo\u1ea1i b\u1ecf l\u1edbp v\u00f4i c\u1ee7a l\u1edbp \u201csmear layer\u201d. Ngo\u00e0i kh\u1ea3 n\u0103ng l\u00e0m s\u1ea1ch, c\u00e1c ch\u1ea5t chelate c\u00f2n c\u00f3 th\u1ec3 lo\u1ea1i b\u1ecf \u0111\u01b0\u1ee3c c\u00e1c m\u00e0ng sinh h\u1ecdc b\u00e1m tr\u00ean th\u00e0nh \u1ed1ng t\u1ee7y. \u0110i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 gi\u1ea3i th\u00edch t\u1ea1i sao dung d\u1ecbch b\u01a1m r\u1eeda EDTA \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh c\u00f3 hi\u1ec7u qu\u1ea3 cao h\u01a1n n\u01b0\u1edbc mu\u1ed1i sinh l\u00fd trong vi\u1ec7c gi\u1ea3m vi sinh v\u1eadt trong \u1ed1ng t\u1ee7y m\u1eb7c d\u00f9 kh\u1ea3 n\u0103ng kh\u00e1ng khu\u1ea9n c\u1ee7a n\u00f3 l\u00e0 c\u00f3 h\u1ea1n.<\/p>\n

          T\u00e1c \u0111\u1ed9ng c\u1ee7a c\u00e1c ch\u1ea5t chelate trong vi\u1ec7c \u0111i\u1ec1u tr\u1ecb c\u00e1c \u1ed1ng t\u1ee7y h\u1eb9p, cong v\u00e0 canxi h\u00f3a \u0111\u1ec3 t\u1ea1o ra \u0111\u01b0\u1eddng tr\u01b0\u1ee3t ph\u1ee5 thu\u1ed9c v\u00e0o c\u1ea3 \u0111\u1ed9 r\u1ed9ng c\u1ee7a \u1ed1ng t\u1ee7y v\u00e0 l\u01b0\u1ee3ng ch\u1ea5t ho\u1ea1t \u0111\u1ed9ng c\u00f3 s\u1eb5n, v\u00ec qu\u00e1 tr\u00ecnh h\u1ee7y kho\u00e1ng canxi s\u1ebd ti\u1ebfp di\u1ec5n cho \u0111\u1ebfn khi t\u1ea5t c\u1ea3 c\u00e1c ch\u1ea5t chelate \u0111\u1ec1u t\u1ea1o th\u00e0nh ph\u1ee9c ch\u1ea5t v\u1edbi canxi.<\/p>\n

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          1. \n

            T\u01b0\u01a1ng t\u00e1c v\u1edbi NaOCl<\/h2>\n<\/li>\n<\/ol>\n

            Tr\u00ecnh t\u1ef1 m\u00e0 m\u00f4 ng\u00e0 th\u00e0nh \u1ed1ng t\u1ee7y \u0111\u01b0\u1ee3c ti\u1ebfp x\u00fac v\u1edbi NaOCl v\u00e0 EDTA c\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn m\u1ee9c \u0111\u1ed9 x\u00f3i m\u00f2n m\u00f4 dentin tr\u00ean th\u00e0nh \u1ed1ng t\u1ee7y ch\u00ednh. Trong nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o b\u1edfi Qian v\u00e0 c\u1ed9ng s\u1ef1, kh\u00f4ng c\u00f3 s\u1ef1 x\u00f3i m\u00f2n n\u00e0o \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n khi c\u00e1c ch\u1ea5t h\u1ee7y kho\u00e1ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 m\u1ed9t l\u1ea7n r\u1eeda cu\u1ed1i sau khi b\u01a1m r\u1eeda b\u1eb1ng NaOCl. Tuy nhi\u00ean, x\u00f3i m\u00f2n m\u00f4 ng\u00e0 xung quanh v\u00e0 gi\u1eefa c\u00e1c \u1ed1ng ng\u00e0 \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n khi EDTA \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng tr\u01b0\u1edbc, sau \u0111\u00f3 l\u00e0 5,25% NaOCl.<\/p>\n

            Tuy nhi\u00ean, EDTA l\u00e0m m\u1ea5t kh\u1ea3 n\u0103ng tan m\u00f4 c\u1ee7a NaOCl, b\u1edfi h\u1ea7u h\u1ebft c\u00e1c ph\u1ea7n t\u1eed clo t\u1ef1 do kh\u00f4ng \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n trong khi k\u1ebft h\u1ee3p hai dung d\u1ecbch n\u00e0y. Trong th\u1ef1c h\u00e0nh l\u00e2m s\u00e0ng, \u0111i\u1ec1u n\u00e0y c\u00f3 ngh\u0129a l\u00e0 EDTA v\u00e0 NaOCl n\u00ean \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng ri\u00eang bi\u1ec7t. Trong quy tr\u00ecnh b\u01a1m r\u1eeda xen k\u1ebd, l\u01b0\u1ee3ng l\u1edbn NaOCl n\u00ean \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 r\u1eeda s\u1ea1ch c\u00e1c m\u1ea3nh v\u1ee5n c\u1ee7a EDTA \u0111\u00e3 \u0111\u01b0\u1ee3c trung h\u00f2a b\u1edfi n\u01b0\u1edbc mu\u1ed1i sinh l\u00fd<\/p>\n

              \n
            1. \n

              T\u01b0\u01a1ng t\u00e1c v\u1edbi CHX<\/h2>\n<\/li>\n<\/ol>\n

              Trong \u0111i\u1ec1u ki\u1ec7n b\u00ecnh th\u01b0\u1eddng, dung d\u1ecbch CHX kh\u00f4ng h\u00f2a tan trong EDTA. K\u1ebft qu\u1ea3 l\u00e0 k\u1ebft t\u1ee7a \u0111\u01b0\u1ee3c t\u1ea1o th\u00e0nh, \u0111\u00e2y l\u00e0 m\u1ed9t mu\u1ed1i \u0111\u01b0\u1ee3c h\u00ecnh th\u00e0nh b\u1edfi s\u1ef1 trung h\u00f2a \u0111i\u1ec7n t\u00edch c\u1ee7a CHX cationic b\u1eb1ng EDTA anionic.<\/p>\n

              Ph\u01b0\u01a1ng tr\u00ecnh ion l\u00e0:<\/p>\n

              2HEDTA3- (aq) + 3H2CHX2+ (aq) \u2194 (HEDTA)2(H2CHX)3 (S)<\/p>\n

              K\u1ebft t\u1ee7a n\u00e0y \u0111\u01b0\u1ee3c bi\u1ebft l\u00e0 l\u00e0m gi\u1ea3m kh\u1ea3 n\u0103ng c\u1ee7a EDTA trong vi\u1ec7c lo\u1ea1i b\u1ecf l\u1edbp \u201csmear layer\u201d<\/p>\n

                \n
              1. \n

                T\u01b0\u01a1ng t\u00e1c v\u1edbi nhi\u1ec7t<\/h2>\n<\/li>\n<\/ol>\n

                T\u0103ng nhi\u1ec7t \u0111\u1ed9 c\u1ee7a dung d\u1ecbch EDTA l\u00e0 \u0111i\u1ec1u kh\u00f4ng mong mu\u1ed1n, b\u1edfi ch\u1ea5t chelate c\u00f3 m\u1ed9t ph\u1ea1m vi nhi\u1ec7t \u0111\u1ed9 m\u00e0 ch\u00fang c\u00f3 th\u1ec3 ho\u1ea1t \u0111\u1ed9ng t\u1ed1t nh\u1ea5t. Khi EDTA \u0111\u01b0\u1ee3c \u0111un n\u00f3ng t\u1eeb 20 \u0111\u1ebfn 90\u00b0C, kh\u1ea3 n\u0103ng k\u1ebft h\u1ee3p canxi gi\u1ea3m.<\/p>\n

                Ngu\u1ed3n tham kh\u1ea3o<\/p>\n

                  \n
                1. Martos J, Ferrer Luque CM, Gonz\u00e1lez-Rodr\u00edguez MP, Arias-Moliz MT, Baca P. Antimicrobial activity of essential oils and chloroform alone and combinated with cetrimide against Enterococcus faecalis biofi lm. Eur J Microbiol Immunol (Bp). 2013;3(1):44\u20138.<\/li>\n
                2. Kele\u015f A, K\u00f6seo\u011flu M. Dissolution of root canal sealers in EDTA and NaOCl solutions. J Am Dent Assoc. 2009;140(1):74\u20139<\/li>\n
                3. European Society of Endodontology. Quality guidelines for endodontic treatment: consensus report of the European Society of Endodontology. Int Endod J. 2006;39(12):921\u201330.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

                  Ethylenediaminetetraacetic acid (EDTA) l\u00e0 m\u1ed9t trong nh\u1eefng dung d\u1ecbch b\u01a1m r\u1eeda ph\u1ed5 bi\u1ebfn trong \u0111i\u1ec1u tr\u1ecb n\u1ed9i nha, v\u1edbi t\u00e1c d\u1ee5ng h\u00f2a tan m\u00f4 kho\u00e1ng h\u00f3a v\u00e0 c\u00e1c m\u1ea3nh v\u1ee5n ng\u00e0 trong \u1ed1ng t\u1ee7y. B\u00e0i vi\u1ebft n\u00e0y s\u1ebd cung c\u1ea5p nh\u1eefng ki\u1ebfn th\u1ee9c v\u1ec1 c\u01a1 ch\u1ebf c\u0169ng nh\u01b0 \u1ee9ng d\u1ee5ng trong l\u00e2m s\u00e0ng c\u1ee7a dung […]<\/p>\n","protected":false},"author":35,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[28,33],"tags":[3],"yoast_head":"\nDung d\u1ecbch b\u01a1m r\u1eeda: Ethylene Diamine Tetraacetic Acid (EDTA)<\/title>\n<meta name=\"description\" content=\"B\u00e0i vi\u1ebft n\u00e0y s\u1ebd cung c\u1ea5p nh\u1eefng ki\u1ebfn th\u1ee9c v\u1ec1 c\u01a1 ch\u1ebf c\u0169ng nh\u01b0 \u1ee9ng d\u1ee5ng trong l\u00e2m s\u00e0ng c\u1ee7a dung d\u1ecbch b\u01a1m r\u1eeda EDTA trong \u0111i\u1ec1u tr\u1ecb n\u1ed9i nha.\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" 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