{"id":20246,"date":"2023-04-15T23:00:35","date_gmt":"2023-04-15T16:00:35","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=20246"},"modified":"2023-04-17T14:26:47","modified_gmt":"2023-04-17T07:26:47","slug":"tuong-tac-thuoc-giua-digoxin-va-quinidine","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/15\/tuong-tac-thuoc-giua-digoxin-va-quinidine\/","title":{"rendered":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine"},"content":{"rendered":"<p><strong>T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine l\u00e0 m\u1ed9t trong nh\u1eefng t\u01b0\u01a1ng t\u00e1c nguy hi\u1ec3m nh\u1ea5t gi\u1eefa c\u00e1c lo\u1ea1i thu\u1ed1c. Digoxin l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n nh\u1ecbp tim v\u00e0 t\u0103ng c\u01b0\u1eddng l\u1ef1c co b\u00f3p c\u1ee7a tim, trong khi \u0111\u00f3 Quinidine l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n nh\u1ecbp tim. Khi s\u1eed d\u1ee5ng c\u00f9ng l\u00fac, Quinidine c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Digoxin trong c\u01a1 th\u1ec3 v\u00e0 d\u1ec5 d\u00e0ng g\u00e2y ra t\u00e1c d\u1ee5ng ph\u1ee5. Do \u0111\u00f3, vi\u1ec7c \u0111\u00e1nh gi\u00e1 t\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine l\u00e0 r\u1ea5t quan tr\u1ecdng \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o an to\u00e0n trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb b\u1ec7nh<\/strong><\/p>\n<h2><strong>1.Gi\u1edbi thi\u1ec7u chung\u00a0<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">T\u01b0\u01a1ng t\u00e1c thu\u1ed1c &#8211; thu\u1ed1c l\u00e0 hi\u1ec7n t\u01b0\u1ee3ng x\u1ea3y ra khi hai ho\u1eb7c nhi\u1ec1u lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng c\u00f9ng l\u00fac v\u00e0 t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn c\u01a1 th\u1ec3. T\u01b0\u01a1ng t\u00e1c n\u00e0y c\u00f3 th\u1ec3 l\u00e0m t\u0103ng ho\u1eb7c gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a c\u00e1c lo\u1ea1i thu\u1ed1c, g\u00e2y ra t\u00e1c d\u1ee5ng ph\u1ee5 ho\u1eb7c th\u1eadm ch\u00ed c\u00f3 th\u1ec3 g\u00e2y nguy hi\u1ec3m \u0111\u1ebfn s\u1ee9c kh\u1ecfe. C\u00f3 nhi\u1ec1u nguy\u00ean nh\u00e2n d\u1eabn \u0111\u1ebfn t\u01b0\u01a1ng t\u00e1c thu\u1ed1c &#8211; thu\u1ed1c kh\u00e1c nhau v\u00e0 vi\u1ec7c \u0111\u00e1nh gi\u00e1 \u0111\u1ec3 ki\u1ec3m so\u00e1t c\u00e1c c\u1eb7p t\u01b0\u01a1ng t\u00e1c thu\u1ed1c x\u1ea3y ra trong \u0111i\u1ec1u tr\u1ecb l\u00e0 r\u1ea5t quan tr\u1ecdng m\u00e0 kh\u00f4ng ch\u1ec9 c\u00e1c b\u00e1c s\u0129, d\u01b0\u1ee3c s\u0129 l\u00e2m s\u00e0ng m\u00e0 b\u1ec7nh nh\u00e2n c\u0169ng c\u1ea7n \u0111\u01b0\u1ee3c h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng \u0111\u00fang li\u1ec1u l\u01b0\u1ee3ng v\u00e0 tu\u00e2n th\u1ee7 nghi\u00eam ng\u1eb7t\u00a0<\/span><\/p>\n<figure id=\"attachment_20251\" aria-describedby=\"caption-attachment-20251\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-20251\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Drug-Interactions-Pharmacists-Should-Know-300x169.png\" alt=\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c - thu\u1ed1c\" width=\"300\" height=\"169\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Drug-Interactions-Pharmacists-Should-Know-300x169.png 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Drug-Interactions-Pharmacists-Should-Know.png 560w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-20251\" class=\"wp-caption-text\">T\u01b0\u01a1ng t\u00e1c thu\u1ed1c &#8211; thu\u1ed1c<\/figcaption><\/figure>\n<h2><strong>2.Th\u00f4ng tin thu\u1ed1c li\u00ean quan \u0111\u1ebfn Digoxin<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">2.1 Nh\u00f3m d\u01b0\u1ee3c l\u00fd v\u00e0 c\u00f4ng d\u1ee5ng\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\"><a href=\"https:\/\/vinmec.com\/vi\/thong-tin-duoc\/thuoc-digoxin-cong-dung-chi-dinh-va-luu-y-khi-dung\/\">Digoxin<\/a> l\u00e0 m\u1ed9t Glycosid tr\u1ee3 tim v\u00e0 thu\u1ed9c nh\u00f3m Digitalis. Digoxin \u0111\u01b0\u1ee3c s\u1ef1 ch\u1ea5p thu\u1eadn c\u1ee7a FDA v\u00e0o n\u0103m 1954 v\u00e0 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c v\u1ea5n \u0111\u1ec1 tim m\u1ea1ch kh\u00e1c nhau nh\u01b0 rung t\u00e2m nh\u0129, suy tim t\u1eeb nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh. Trong th\u1ef1c t\u1ebf, Digoxin \u0111\u01b0\u1ee3c d\u00e0nh l\u00e0m thu\u1ed1c d\u1ef1 ph\u00f2ng khi c\u00e1c thu\u1ed1c \u0111\u1ea7u tay nh\u01b0 thu\u1ed1c ch\u1eb9n Beta v\u00e0 thu\u1ed1c ch\u1eb9n k\u00eanh Canxi kh\u00f4ng hi\u1ec7u qu\u1ea3<\/span><\/p>\n<figure id=\"attachment_20254\" aria-describedby=\"caption-attachment-20254\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-20254\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Digoxin-300x300.webp\" alt=\"Digoxin\" width=\"300\" height=\"300\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Digoxin-300x300.webp 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Digoxin-150x150.webp 150w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Digoxin-768x768.webp 768w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Digoxin.webp 1000w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-20254\" class=\"wp-caption-text\">Digoxin<\/figcaption><\/figure>\n<p><span style=\"font-weight: 400;\">2.2 C\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Digoxin c\u00f3 hai c\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng c\u00f3 ch\u1ecdn l\u1ecdc t\u00f9y theo ch\u1ec9 \u0111\u1ecbnh\u00a0<\/span><\/p>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ionotropic t\u00edch c\u1ef1c: Digoxin \u1ee9c ch\u1ebf \u0111\u1ea3o ng\u01b0\u1ee3c ho\u1ea1t \u0111\u1ed9ng c\u1ee7a b\u01a1m Na+-K+-ATPase c\u1ee7a c\u01a1 tim, m\u1ed9t lo\u1ea1i enzyme ki\u1ec3m so\u00e1t s\u1ef1 di chuy\u1ec3n c\u00e1c ion v\u00e0o tim. Digoxin g\u00e2y ra s\u1ef1 t\u0103ng Natri n\u1ed9i b\u00e0o s\u1ebd th\u00fac \u0111\u1ea9y d\u00f2ng Canxi v\u00e0o tim v\u00e0 l\u00e0m t\u0103ng kh\u1ea3 n\u0103ng co b\u00f3p c\u1ee7a tim<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u1ee8c ch\u1ebf n\u00fat nh\u0129 th\u1ea5t (AV): Digoxin k\u00edch th\u00edch h\u1ec7 th\u1ea7n kinh ph\u00f3 giao c\u1ea3m, l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh d\u1eabn truy\u1ec1n \u0111i\u1ec7n trong n\u00fat nh\u0129 th\u1ea5t d\u1eabn \u0111\u1ebfn l\u00e0m gi\u1ea3m nh\u1ecbp tim<\/span><\/li>\n<\/ol>\n<p><span style=\"font-weight: 400;\">2.3 T\u00e1c d\u1ee5ng ph\u1ee5\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Digoxin c\u00f3 th\u1ec3 l\u00e0m r\u1ed1i lo\u1ea1n nh\u1ecbp tim g\u00e2y t\u1eed vong v\u00e0 t\u1ec9 l\u1ec7 \u0111\u1ed9c t\u00ednh t\u0103ng l\u00ean khi n\u1ed3ng \u0111\u1ed9 Digoxin trong huy\u1ebft thanh \u0111\u1ea1t tr\u00ean 2,0g\/ml. Tri\u1ec7u ch\u1ee9ng ph\u1ed5 bi\u1ebfn kh\u00e1c bao g\u1ed3m bu\u1ed3n n\u00f4n, n\u00f4n, ch\u00e1n \u0103n, thay \u0111\u1ed5i m\u00e0u s\u1eafc c\u1ee7a m\u1eaft, ph\u00e1t ban, \u0111au \u0111\u1ea7u<\/span><\/p>\n<p><span style=\"font-weight: 400;\">2.4 Tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Khi s\u1eed d\u1ee5ng qu\u00e1 li\u1ec1u Digoxin c\u00f3 th\u1ec3 g\u00e2y r\u1ed1i lo\u1ea1n nh\u1ecbp tim ho\u1eb7c t\u0103ng Kali m\u00e1u \u00e1c t\u00ednh, t\u00e1c \u0111\u1ed9ng \u1ea3nh h\u01b0\u1edfng tr\u00ean h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng nh\u01b0 bu\u1ed3n ng\u1ee7, m\u1ec7t m\u1ecfi, ch\u00f3ng m\u1eb7t, \u0111au \u0111\u1ea7u, \u1ea3o gi\u00e1c, nh\u1ea7m l\u1eabn ho\u1eb7c ch\u00f3ng m\u1eb7t, \u0111\u1ed9ng kinh (hi\u1ebfm g\u1eb7p)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">2.5 Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Digoxin ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh trong nh\u1eefng tr\u01b0\u1eddng h\u1ee3p sau: nh\u1ed3i m\u00e1u c\u01a1 tim c\u1ea5p t\u00ednh, qu\u00e1 m\u1eabn, rung t\u00e2m th\u1ea5t, vi\u00eam c\u01a1 tim, h\u1ea1 Magie m\u00e1u, h\u1ea1 Kali m\u00e1u, h\u1ed9i ch\u1ee9ng Wolff-Parkinson-White<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Vi\u1ec7c s\u1eed d\u1ee5ng Digoxin c\u1ea7n th\u1eadn tr\u1ecdng trong nh\u1eefng tr\u01b0\u1eddng h\u1ee3p: t\u0103ng ho\u1eb7c h\u1ea1 Canxi huy\u1ebft, suy th\u1eadn, nh\u1ecbp tim ch\u1eadm, vi\u00eam m\u00e0ng ngo\u00e0i tim co th\u1eaft<\/span><\/p>\n<h2><strong>3.Th\u00f4ng tin thu\u1ed1c li\u00ean quan \u0111\u1ebfn Quinidine\u00a0<\/strong><\/h2>\n<h3><span style=\"font-weight: 400;\">3.1 Nh\u00f3m d\u01b0\u1ee3c l\u00fd v\u00e0 c\u00f4ng d\u1ee5ng\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Quinidine l\u00e0 thu\u1ed1c ch\u1ed1ng lo\u1ea1n nh\u1ecbp nh\u00f3m IA \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111i\u1ec1u tr\u1ecb rung nh\u0129, r\u1ed1i lo\u1ea1n nh\u1ecbp tim th\u1ea5t th\u01b0\u1eddng, nh\u1ecbp th\u1ea5t nhanh, h\u1ed9i ch\u1ee9ng Brugada, h\u1ed9i ch\u1ee9ng Wolff &#8211; Parkinson &#8211; White. Quinidine c\u0169ng \u0111\u01b0\u1ee3c c\u00f4ng nh\u1eadn l\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb b\u1ec7nh s\u1ed1t r\u00e9t nghi\u00eam tr\u1ecdng c\u00f3 hi\u1ec7u qu\u1ea3\u00a0<\/span><\/p>\n<figure id=\"attachment_20258\" aria-describedby=\"caption-attachment-20258\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-20258\" src=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/thuoc-phenelzine-2-1-300x120.jpg\" alt=\"Quinidine\" width=\"300\" height=\"120\" srcset=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/thuoc-phenelzine-2-1-300x120.jpg 300w, http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/thuoc-phenelzine-2-1.jpg 768w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-20258\" class=\"wp-caption-text\">Quinidine<\/figcaption><\/figure>\n<h3><span style=\"font-weight: 400;\">3.2 C\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Quinidine \u1ee9c ch\u1ebf d\u00f2ng Natri \u0111i v\u00e0o nhanh l\u00e0m gi\u1ea3m t\u00ednh d\u1ec5 b\u1ecb k\u00edch th\u00edch c\u1ee7a c\u01a1 tim t\u1eeb \u0111\u00f3 k\u00e9o d\u00e0i \u0111i\u1ec7n th\u1ebf ho\u1ea1t \u0111\u1ed9ng v\u00e0 l\u00e0m gi\u1ea3m t\u00ednh t\u1ef1 \u0111\u1ed9ng c\u1ee7a c\u01a1 tim. Ngo\u00e0i ra, Quinidine l\u00e0m gi\u1ea3m d\u00f2ng Kali trong qu\u00e1 tr\u00ecnh t\u00e1i c\u1ef1c gi\u00fap ph\u00e1t huy t\u00e1c d\u1ee5ng ch\u1ed1ng lo\u1ea1n nh\u1ecbp tim\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">M\u1eb7c kh\u00e1c, Quinidine ho\u1ea1t \u0111\u1ed9ng nh\u01b0 m\u1ed9t t\u00e1c nh\u00e2n ch\u1ed1ng s\u1ed1t r\u00e9t b\u1eb1ng c\u00e1ch ng\u0103n ch\u1eb7n giai \u0111o\u1ea1n h\u1ed3ng c\u1ea7u c\u1ee7a lo\u00e0i Plasmodium, thu\u1ed1c \u0111\u01b0\u1ee3c t\u00edch t\u1ee5 trong kh\u00f4ng b\u00e0o v\u00e0 t\u1ea1o ph\u1ee9c h\u1ee3p v\u1edbi Heme \u0111\u1ec3 ng\u0103n s\u1ef1 h\u00ecnh th\u00e0nh kh\u00f4ng b\u00e0o trong k\u00fd sinh tr\u00f9ng<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">3.3 T\u00e1c d\u1ee5ng ph\u1ee5\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Quinidine g\u00e2y ra c\u00e1c t\u00e1c ph\u1ee5 tr\u00ean nhi\u1ec1u c\u01a1 quan kh\u00e1c nhau\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Tr\u00ean tim m\u1ea1ch: \u0111\u00e1nh tr\u1ed1ng ng\u1ef1c, \u0111au th\u1eaft ng\u1ef1c, r\u1ed1i lo\u1ea1n nh\u1ecbp tim, h\u1ea1 K+ m\u00e1u\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Tr\u00ean h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng: ch\u00f3ng m\u1eb7t, m\u1ec7t m\u1ecfi, nh\u1ee9c \u0111\u1ea7u, r\u1ed1i lo\u1ea1n gi\u1ea5c ng\u1ee7, h\u1ed3i h\u1ed9p<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Tr\u00ean da li\u1ec5u: ph\u00e1t ban da<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Tr\u00ean h\u1ec7 ti\u00eau h\u00f3a: nhi\u1ec5m \u0111\u1ed9c gan, ti\u00eau ch\u1ea3y, r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a, bu\u1ed3n n\u00f4n v\u00e0 n\u00f4n, vi\u00eam th\u1ef1c qu\u1ea3n<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Tr\u00ean c\u01a1 v\u00e0 x\u01b0\u01a1ng: run, y\u1ebfu c\u01a1<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Tr\u00ean nh\u00e3n khoa: r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Kh\u00e1c: s\u1ed1t, ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn, t\u00e1n huy\u1ebft \u1edf b\u1ec7nh nh\u00e2n b\u1ecb thi\u1ebfu G6DP<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">3.4 Tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">N\u1ebfu s\u1eed d\u1ee5ng Quinidine qu\u00e1 li\u1ec1u s\u1ebd g\u1eb7p ph\u1ea3i c\u00e1c tri\u1ec7u ch\u1ee9ng sau: m\u00f9 l\u00f2a, m\u1edd m\u1eaft \/ thay \u0111\u1ed5i th\u1ecb l\u1ef1c, \u0111au ng\u1ef1c, ch\u00f3ng m\u1eb7t, ng\u1ea5t x\u1ec9u, nh\u1ecbp tim nhanh ho\u1eb7c kh\u00f4ng \u0111\u1ec1u, bu\u1ed3n ng\u1ee7<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">3.5 Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Quinidine ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh trong tr\u01b0\u1eddng h\u1ee3p: qu\u00e1 m\u1eabn, xu\u1ea5t huy\u1ebft, gi\u1ea3m ti\u1ec3u c\u1ea7u, block nh\u0129 th\u1ea5t (AV)<\/span><\/p>\n<h2><strong>4.T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine<\/strong><\/h2>\n<h3><span style=\"font-weight: 400;\">4.1 M\u1ee9c \u0111\u1ed9 t\u01b0\u01a1ng t\u00e1c t\u1eeb nhi\u1ec1u ngu\u1ed3n kh\u00e1c nhau\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Medscape: Nghi\u00eam tr\u1ecdng\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Drugs interactions checker: Nghi\u00eam tr\u1ecdng\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Micromedex drug interaction: Nghi\u00eam tr\u1ecdng\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lexicomp: Nghi\u00eam tr\u1ecdng\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">4.2 H\u1eadu qu\u1ea3 t\u01b0\u01a1ng t\u00e1c gi\u1eefa Digoxin v\u00e0 Quinidine\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Khi Quinidine \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi Digoxin, Quinidine \u1ee9c ch\u1ebf P-glycoprotein d\u1eabn \u0111\u1ebfn t\u0103ng h\u1ea5p thu Digoxin v\u00e0 gi\u1ea3m \u0111\u00e0o th\u1ea3i Digoxin ch\u1ee7 y\u1ebfu qua th\u1eadn d\u1eabn \u0111\u1ebfn s\u1ef1 gia t\u0103ng \u0111\u00e1ng k\u1ec3 n\u1ed3ng \u0111\u1ed9 Digoxin trong huy\u1ebft t\u01b0\u01a1ng \u1edf h\u01a1n 90% b\u1ec7nh nh\u00e2n v\u00e0 g\u00e2y ra \u0111\u1ed9c t\u00ednh qu\u00e1 li\u1ec1u Digoxin<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">4.3 Bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba \/ c\u00e1ch x\u1eed tr\u00ed<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Cho b\u00e1c s\u0129 bi\u1ebft \u0111\u1ea7y \u0111\u1ee7 th\u00f4ng tin v\u00e0 t\u00ecnh h\u00ecnh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng c\u00f9ng l\u00fac Digoxin v\u00e0 Quinidine. Khi c\u00f3 tri\u1ec7u ch\u1ee9ng do h\u1eadu qu\u1ea3 t\u01b0\u01a1ng t\u00e1c ph\u1ea3i b\u00e1o cho b\u00e1c s\u0129 ho\u1eb7c d\u01b0\u1ee3c s\u0129 l\u00e2m s\u00e0ng bi\u1ebft \u0111\u1ec3 k\u1ecbp th\u1eddi x\u1eed l\u00fd.\u00a0 Kh\u00f4ng ng\u1eebng s\u1eed d\u1ee5ng b\u1ea5t k\u1ef3 lo\u1ea1i thu\u1ed1c n\u00e0o m\u00e0 kh\u00f4ng b\u00e1o cho b\u00e1c s\u0129 tr\u01b0\u1edbc<\/span><\/p>\n<p><span style=\"font-weight: 400;\">H\u00e3y li\u00ean h\u1ec7 v\u1edbi ch\u00fang t\u00f4i Hotline<\/span><a href=\"https:\/\/www.vinmec.com\/\"><span style=\"font-weight: 400;\"> Vinmec<\/span><\/a><span style=\"font-weight: 400;\"> n\u1ebfu b\u1ea1n mu\u1ed1n \u0111\u1eb7t l\u1ecbch kh\u00e1m ho\u1eb7c c\u00f3 b\u1ea5t k\u1ef3 th\u1eafc m\u1eafc n\u00e0o<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ngu\u1ed3n: T\u1ed5ng h\u1ee3p<\/span><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine l\u00e0 m\u1ed9t trong nh\u1eefng t\u01b0\u01a1ng t\u00e1c nguy hi\u1ec3m nh\u1ea5t gi\u1eefa c\u00e1c lo\u1ea1i thu\u1ed1c. Digoxin l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n nh\u1ecbp tim v\u00e0 t\u0103ng c\u01b0\u1eddng l\u1ef1c co b\u00f3p c\u1ee7a tim, trong khi \u0111\u00f3 Quinidine l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 [&hellip;]<\/p>\n","protected":false},"author":54,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[12,33],"tags":[3],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine - Vinmec<\/title>\n<meta name=\"description\" content=\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine l\u00e0 m\u1ed9t trong nh\u1eefng t\u01b0\u01a1ng t\u00e1c nguy hi\u1ec3m nh\u1ea5t gi\u1eefa c\u00e1c lo\u1ea1i thu\u1ed1c v\u00ec g\u00e2y nhi\u1ec1u h\u1eadu qu\u1ea3 cho c\u01a1 th\u1ec3\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine - Vinmec\" \/>\n<meta property=\"og:description\" content=\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine l\u00e0 m\u1ed9t trong nh\u1eefng t\u01b0\u01a1ng t\u00e1c nguy hi\u1ec3m nh\u1ea5t gi\u1eefa c\u00e1c lo\u1ea1i thu\u1ed1c v\u00ec g\u00e2y nhi\u1ec1u h\u1eadu qu\u1ea3 cho c\u01a1 th\u1ec3\" \/>\n<meta property=\"og:url\" content=\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/15\/tuong-tac-thuoc-giua-digoxin-va-quinidine\/\" \/>\n<meta property=\"og:site_name\" content=\"Vinmec\" \/>\n<meta property=\"article:published_time\" content=\"2023-04-15T16:00:35+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-04-17T07:26:47+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Drug-Interactions-Pharmacists-Should-Know-300x169.png\" \/>\n<meta name=\"author\" content=\"Nguy\u1ec5n Ng\u1ecdc Tho\u1ea1i Nhi\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Nguy\u1ec5n Ng\u1ecdc Tho\u1ea1i Nhi\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/15\/tuong-tac-thuoc-giua-digoxin-va-quinidine\/\",\"url\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/15\/tuong-tac-thuoc-giua-digoxin-va-quinidine\/\",\"name\":\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine - Vinmec\",\"isPartOf\":{\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/#website\"},\"datePublished\":\"2023-04-15T16:00:35+00:00\",\"dateModified\":\"2023-04-17T07:26:47+00:00\",\"author\":{\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/55407b7fd81e248fc677fffab3aac771\"},\"description\":\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine l\u00e0 m\u1ed9t trong nh\u1eefng t\u01b0\u01a1ng t\u00e1c nguy hi\u1ec3m nh\u1ea5t gi\u1eefa c\u00e1c lo\u1ea1i thu\u1ed1c v\u00ec g\u00e2y nhi\u1ec1u h\u1eadu qu\u1ea3 cho c\u01a1 th\u1ec3\",\"breadcrumb\":{\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/15\/tuong-tac-thuoc-giua-digoxin-va-quinidine\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/15\/tuong-tac-thuoc-giua-digoxin-va-quinidine\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/15\/tuong-tac-thuoc-giua-digoxin-va-quinidine\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"http:\/\/noithathoaphat.in\/ctv\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine\"}]},{\"@type\":\"WebSite\",\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/#website\",\"url\":\"http:\/\/noithathoaphat.in\/ctv\/\",\"name\":\"Vinmec\",\"description\":\"H\u1ec7 th\u1ed1ng Y t\u1ebf Vinmec\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"http:\/\/noithathoaphat.in\/ctv\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/55407b7fd81e248fc677fffab3aac771\",\"name\":\"Nguy\u1ec5n Ng\u1ecdc Tho\u1ea1i Nhi\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/image\/\",\"url\":\"http:\/\/2.gravatar.com\/avatar\/2cb6fe9c8b954a7fbd43938a66c2c4b9?s=96&d=mm&r=g\",\"contentUrl\":\"http:\/\/2.gravatar.com\/avatar\/2cb6fe9c8b954a7fbd43938a66c2c4b9?s=96&d=mm&r=g\",\"caption\":\"Nguy\u1ec5n Ng\u1ecdc Tho\u1ea1i Nhi\"},\"url\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/author\/nguyenngocthoainhigmail-com\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine - Vinmec","description":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine l\u00e0 m\u1ed9t trong nh\u1eefng t\u01b0\u01a1ng t\u00e1c nguy hi\u1ec3m nh\u1ea5t gi\u1eefa c\u00e1c lo\u1ea1i thu\u1ed1c v\u00ec g\u00e2y nhi\u1ec1u h\u1eadu qu\u1ea3 cho c\u01a1 th\u1ec3","robots":{"index":"noindex","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"og_locale":"en_US","og_type":"article","og_title":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine - Vinmec","og_description":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine l\u00e0 m\u1ed9t trong nh\u1eefng t\u01b0\u01a1ng t\u00e1c nguy hi\u1ec3m nh\u1ea5t gi\u1eefa c\u00e1c lo\u1ea1i thu\u1ed1c v\u00ec g\u00e2y nhi\u1ec1u h\u1eadu qu\u1ea3 cho c\u01a1 th\u1ec3","og_url":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/15\/tuong-tac-thuoc-giua-digoxin-va-quinidine\/","og_site_name":"Vinmec","article_published_time":"2023-04-15T16:00:35+00:00","article_modified_time":"2023-04-17T07:26:47+00:00","og_image":[{"url":"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/Drug-Interactions-Pharmacists-Should-Know-300x169.png"}],"author":"Nguy\u1ec5n Ng\u1ecdc Tho\u1ea1i Nhi","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Nguy\u1ec5n Ng\u1ecdc Tho\u1ea1i Nhi","Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/15\/tuong-tac-thuoc-giua-digoxin-va-quinidine\/","url":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/15\/tuong-tac-thuoc-giua-digoxin-va-quinidine\/","name":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine - Vinmec","isPartOf":{"@id":"http:\/\/noithathoaphat.in\/ctv\/#website"},"datePublished":"2023-04-15T16:00:35+00:00","dateModified":"2023-04-17T07:26:47+00:00","author":{"@id":"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/55407b7fd81e248fc677fffab3aac771"},"description":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine l\u00e0 m\u1ed9t trong nh\u1eefng t\u01b0\u01a1ng t\u00e1c nguy hi\u1ec3m nh\u1ea5t gi\u1eefa c\u00e1c lo\u1ea1i thu\u1ed1c v\u00ec g\u00e2y nhi\u1ec1u h\u1eadu qu\u1ea3 cho c\u01a1 th\u1ec3","breadcrumb":{"@id":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/15\/tuong-tac-thuoc-giua-digoxin-va-quinidine\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/15\/tuong-tac-thuoc-giua-digoxin-va-quinidine\/"]}]},{"@type":"BreadcrumbList","@id":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/15\/tuong-tac-thuoc-giua-digoxin-va-quinidine\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"http:\/\/noithathoaphat.in\/ctv\/"},{"@type":"ListItem","position":2,"name":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Digoxin v\u00e0 Quinidine"}]},{"@type":"WebSite","@id":"http:\/\/noithathoaphat.in\/ctv\/#website","url":"http:\/\/noithathoaphat.in\/ctv\/","name":"Vinmec","description":"H\u1ec7 th\u1ed1ng Y t\u1ebf Vinmec","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"http:\/\/noithathoaphat.in\/ctv\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Person","@id":"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/55407b7fd81e248fc677fffab3aac771","name":"Nguy\u1ec5n Ng\u1ecdc Tho\u1ea1i Nhi","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/image\/","url":"http:\/\/2.gravatar.com\/avatar\/2cb6fe9c8b954a7fbd43938a66c2c4b9?s=96&d=mm&r=g","contentUrl":"http:\/\/2.gravatar.com\/avatar\/2cb6fe9c8b954a7fbd43938a66c2c4b9?s=96&d=mm&r=g","caption":"Nguy\u1ec5n Ng\u1ecdc Tho\u1ea1i Nhi"},"url":"http:\/\/noithathoaphat.in\/ctv\/index.php\/author\/nguyenngocthoainhigmail-com\/"}]}},"_links":{"self":[{"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/posts\/20246"}],"collection":[{"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/users\/54"}],"replies":[{"embeddable":true,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/comments?post=20246"}],"version-history":[{"count":5,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/posts\/20246\/revisions"}],"predecessor-version":[{"id":21823,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/posts\/20246\/revisions\/21823"}],"wp:attachment":[{"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/media?parent=20246"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/categories?post=20246"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/tags?post=20246"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}