{"id":19598,"date":"2023-04-15T19:06:50","date_gmt":"2023-04-15T12:06:50","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=19598"},"modified":"2023-04-17T16:10:02","modified_gmt":"2023-04-17T09:10:02","slug":"tuong-tac-thuoc-giua-fluoxetine-va-phenelzine","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/15\/tuong-tac-thuoc-giua-fluoxetine-va-phenelzine\/","title":{"rendered":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Fluoxetine v\u00e0 Phenelzine"},"content":{"rendered":"

Fluoxetine v\u00e0 Phenelzine l\u00e0 hai lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n t\u00e2m l\u00fd. Tuy nhi\u00ean, khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi hai lo\u1ea1i thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 g\u00e2y ra t\u01b0\u01a1ng t\u00e1c thu\u1ed1c v\u00e0 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ee9c kh\u1ecfe c\u1ee7a b\u1ec7nh nh\u00e2n. Vi\u1ec7c hi\u1ec3u r\u00f5 t\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Fluoxetine v\u00e0 Phenelzine \u0111\u00f3ng vai tr\u00f2 quan tr\u1ecdng \u0111\u1ec3 tr\u00e1nh g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 kh\u00f4ng mong mu\u1ed1n v\u00e0 \u0111\u1ea3m b\u1ea3o hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb.<\/strong><\/p>\n

1.Gi\u1edbi thi\u1ec7u chung\u00a0<\/strong><\/h2>\n

T\u01b0\u01a1ng t\u00e1c thu\u1ed1c \u2013 thu\u1ed1c c\u00f3 th\u1ec3 x\u1ea3y ra khi hai ho\u1eb7c nhi\u1ec1u lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi ho\u1eb7c li\u00ean ti\u1ebfp, g\u00e2y ra c\u00e1c \u1ea3nh h\u01b0\u1edfng kh\u00f4ng mong mu\u1ed1n \u0111\u1ebfn s\u1ee9c kh\u1ecfe v\u00e0 c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb. V\u00ec v\u1eady, hi\u1ec3u r\u00f5 v\u1ec1 t\u01b0\u01a1ng t\u00e1c thu\u1ed1c v\u00e0 c\u00e1ch gi\u1ea3m thi\u1ec3u t\u00e1c \u0111\u1ed9ng c\u1ee7a ch\u00fang \u0111\u1ebfn c\u01a1 th\u1ec3 l\u00e0 r\u1ea5t quan tr\u1ecdng trong vi\u1ec7c \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd. Vi\u1ec7c n\u1eafm k\u1ef9 c\u00e1c c\u1eb7p t\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa c\u00e1c lo\u1ea1i thu\u1ed1c kh\u00e1c nhau gi\u00fap cho c\u00e1c chuy\u00ean gia y t\u1ebf c\u00f3 th\u1ec3 l\u1ef1a ch\u1ecdn v\u00e0 k\u00ea \u0111\u01a1n thu\u1ed1c ph\u00f9 h\u1ee3p cho b\u1ec7nh nh\u00e2n, tr\u00e1nh g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 kh\u00f4ng mong mu\u1ed1n v\u00e0 t\u0103ng hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb.<\/span><\/p>\n

\"T\u01b0\u01a1ng
T\u01b0\u01a1ng t\u00e1c thu\u1ed1c – thu\u1ed1c<\/figcaption><\/figure>\n

2.T\u1ed5ng quan v\u1ec1 Fluoxetine<\/a><\/h2>\n

2.1 Nh\u00f3m d\u01b0\u1ee3c l\u00fd v\u00e0 c\u00f4ng d\u1ee5ng<\/span><\/h3>\n

Fluoxetine l\u00e0 thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m hai v\u00f2ng n\u1eb1m trong nh\u00f3m thu\u1ed1c \u1ee9c ch\u1ebf t\u00e1i h\u1ea5p thu Serotonin c\u00f3 ch\u1ecdn l\u1ecdc (SSRI) v\u00e0 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb tr\u1ea7m c\u1ea3m, r\u1ed1i lo\u1ea1n \u00e1m \u1ea3nh c\u01b0\u1ee1ng ch\u1ebf, r\u1ed1i lo\u1ea1n \u0103n u\u1ed1ng v\u00e0 l\u00e0m gi\u1ea3m tri\u1ec7u ch\u1ee9ng ti\u1ec1n kinh nguy\u1ec7t nh\u01b0 kh\u00f3 ch\u1ecbu, th\u00e8m \u0103n. Thu\u1ed1c c\u00f2n gi\u00fap c\u1ea3i thi\u1ec7n t\u00e2m tr\u1ea1ng, gi\u1ea5c ng\u1ee7, m\u1ee9c n\u0103ng l\u01b0\u1ee3ng v\u00e0 gi\u00fap l\u00e0m gi\u1ea3m s\u1ee3 h\u00e3i v\u00e0 tr\u00e1nh c\u00e1c c\u01a1n ho\u1ea3ng lo\u1ea1n. \u0110\u00f4i khi, Fluoxetine c\u0169ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ch\u1ee9ng nghi\u1ec7n r\u01b0\u1ee3u, r\u1ed1i lo\u1ea1n thi\u1ebfu t\u1eadp trung, h\u1ed9i ch\u1ee9ng Tourette, b\u00e9o ph\u00ec<\/span><\/p>\n

\"Fluoxetin\"
Fluoxetin<\/figcaption><\/figure>\n

2.2 C\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng<\/span><\/h3>\n

Fluoxetine c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc t\u00e1i h\u1ea5p thu Serotonin c\u1ee7a c\u00e1c t\u1ebf b\u00e0o th\u1ea7n kinh\u00a0<\/span><\/p>\n

2.3 T\u00e1c d\u1ee5ng ph\u1ee5\u00a0<\/span><\/h3>\n

Fluoxetine c\u00f3 th\u1ec3 g\u00e2y ra nh\u1eefng t\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p bao g\u1ed3m nh\u1ee9c \u0111\u1ea7u, ti\u00eau ch\u1ea3y, c\u1ea3m th\u1ea5y m\u1ec7t m\u1ecfi, m\u1ea5t ng\u1ee7 v\u00e0 c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng h\u01a1n nh\u01b0 t\u0103ng c\u00e2n ho\u1eb7c gi\u1ea3m c\u00e2n \u0111\u1ed9t ng\u1ed9t, ho ra m\u00e1u, m\u00e1u trong n\u01b0\u1edbc ti\u1ec3u, xu\u1ea5t huy\u1ebft d\u1ea1 d\u00e0y, ch\u1ea3y m\u00e1u t\u1eeb n\u01b0\u1edbu r\u0103ng ho\u1eb7c v\u1ebft b\u1ea7m t\u00edm, c\u1ea3m gi\u00e1c h\u01b0ng ph\u1ea5n ho\u1eb7c k\u00edch th\u00edch qu\u00e1 m\u1ee9c, \u0111au ng\u1ef1c ho\u1eb7c kh\u00f3 th\u1edf, c\u00e1c ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng nghi\u00eam tr\u1ecdng<\/span><\/p>\n

2.4 Tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u\u00a0<\/span><\/h3>\n

C\u00e1c tri\u1ec7u ch\u1ee9ng l\u00e0m d\u1ea5u hi\u1ec7u khi b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng qu\u00e1 li\u1ec1u: l\u00fa l\u1eabn, ch\u00f3ng m\u1eb7t, nh\u1ecbp tim nhanh, ng\u1ea5t x\u1ec9u, co gi\u1eadt, s\u1ed1t, h\u00f4n m\u00ea<\/span><\/p>\n

2.5 Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh\u00a0<\/span><\/h3>\n

Thu\u1ed1c \u0111\u01b0\u1ee3c ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh v\u1edbi c\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng sau m\u1eafc b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, h\u1ed9i ch\u1ee9ng Serotonin, l\u01b0\u1ee3ng Na trong m\u00e1u th\u1ea5p, c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 gan, xu\u1ea5t huy\u1ebft d\u1ea1 d\u00e0y – t\u00e1 tr\u00e0ng – th\u1ef1c qu\u1ea3n, h\u01b0ng c\u1ea3m,…<\/span><\/p>\n

3.T\u1ed5ng quan v\u1ec1 Phenelzine<\/a><\/strong><\/h2>\n

3.1 Nh\u00f3m d\u01b0\u1ee3c l\u00fd v\u00e0 c\u00f4ng d\u1ee5ng\u00a0<\/span><\/h3>\n

Phenelzine l\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf monoamine oxidase (IMAO) m\u1ea1nh thu\u1ed9c d\u1eabn xu\u1ea5t Hydrazine, kh\u00f4ng ch\u1ecdn l\u1ecdc \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb tr\u1ea7m c\u1ea3m, gi\u1ea3i lo \u00e2u \u1edf ng\u01b0\u1eddi l\u1edbn<\/span><\/p>\n

\"Phenelzine\"
Phenelzine<\/figcaption><\/figure>\n

3.2 C\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng\u00a0<\/span><\/h3>\n

Phenelzine \u1ee9c ch\u1ebf kh\u00f4ng thu\u1eadn ngh\u1ecbch c\u00e1c enzyme monoamine oxidase A v\u00e0 B, ng\u0103n kh\u00f4ng cho Serotonin, Norepinephrine v\u00e0 Dopamine b\u1ecb ph\u00e2n h\u1ee7y t\u1eeb \u0111\u00f3 k\u00e9o d\u00e0i t\u00e1c d\u1ee5ng c\u1ee7a c\u00e1c ch\u1ea5t d\u1eabn truy\u1ec1n th\u1ea7n kinh tr\u00ean th\u1ee5 th\u1ec3.\u00a0<\/span><\/p>\n

3.3 T\u00e1c d\u1ee5ng ph\u1ee5\u00a0<\/span><\/h3>\n

Phenelzine c\u00f3 t\u00e1c \u0111\u1ed9ng l\u00ean th\u1ee5 th\u1ec3 GABA v\u00e0 Melatonin g\u00e2y ra ch\u1ee9ng m\u1ea5t ng\u1ee7. S\u1ef1 \u1ee9c ch\u1ebf MAO c\u0169ng ng\u0103n ch\u1eb7n s\u1ef1 ph\u00e2n h\u1ee7y Norepinephrine \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u01a1 tr\u01a1n m\u1ea1ch m\u00e1u. Ngo\u00e0i ra Phenelzine c\u0169ng g\u00e2y m\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 bao g\u1ed3m t\u00e1o b\u00f3n, kh\u00f4 mi\u1ec7ng, thay \u0111\u1ed5i c\u00e2n n\u1eb7ng, bu\u1ed3n n\u00f4n, t\u0103ng c\u00e2n, bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t. C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 hi\u1ebfm g\u1eb7p nh\u01b0ng nghi\u00eam tr\u1ecdng nh\u01b0 xu\u1ea5t huy\u1ebft n\u1ed9i s\u1ecd, h\u1ed9i ch\u1ee9ng Serotonin, ho\u1ea1i t\u1eed gan, co gi\u1eadt<\/span><\/p>\n

3.4 Tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u\u00a0<\/span><\/h3>\n

\u0110\u1ed1i v\u1edbi nh\u1eefng b\u1ec7nh nh\u00e2n d\u00f9ng qu\u00e1 li\u1ec1u Phenelzine, c\u00e1c tri\u1ec7u ch\u1ee9ng c\u00f3 th\u1ec3 t\u1eeb k\u00edch \u0111\u1ed9ng \u0111\u1ebfn h\u00f4n m\u00ea. C\u1ee5 th\u1ec3 bao g\u1ed3m t\u0103ng huy\u1ebft \u00e1p, th\u1edf nhanh, nh\u1ecbp tim nhanh, gi\u00e3n \u0111\u1ed3ng t\u1eed<\/span><\/p>\n

3.5 Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh\u00a0<\/span><\/h3>\n

Phenelzine ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n qu\u00e1 m\u1eabn, suy tim sung huy\u1ebft, suy th\u1eadn n\u1eb7ng, ti\u1ec1n s\u1eed b\u1ec7nh gan<\/span><\/p>\n

4.T\u01b0\u01a1ng t\u00e1c gi\u1eefa Fluoxetine v\u00e0 Phenelzine<\/strong><\/h2>\n

4.1 M\u1ee9c \u0111\u1ed9 t\u01b0\u01a1ng t\u00e1c \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 t\u1eeb nhi\u1ec1u ngu\u1ed3n<\/span><\/h3>\n

Medscape: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh\u00a0<\/span><\/p>\n

Drugs interactions checker: Nghi\u00eam tr\u1ecdng\u00a0<\/span><\/p>\n

Micromedex drug interaction: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh\u00a0<\/span><\/p>\n

Lexicomp: Nghi\u00eam tr\u1ecdng\u00a0<\/span><\/p>\n

4.2 H\u1eadu qu\u1ea3 t\u01b0\u01a1ng t\u00e1c gi\u1eefa Fluoxetine v\u00e0 Phenelzine<\/span><\/h3>\n

Khi s\u1eed d\u1ee5ng c\u00f9ng l\u00fac Fluoxetine v\u00e0 Phenelzine c\u00f3 th\u1ec3 g\u00e2y ra t\u01b0\u01a1ng t\u00e1c d\u1eabn \u0111\u1ebfn t\u0103ng nguy c\u01a1 m\u1eafc h\u1ed9i ch\u1ee9ng Serotonin khi c\u01a1 th\u1ec3 t\u00edch t\u1ee5 qu\u00e1 nhi\u1ec1u Serotonin v\u00e0 g\u00e2y ra nhi\u1ec1u tri\u1ec7u ch\u1ee9ng nh\u01b0 l\u00fa l\u1eabn, \u1ea3o gi\u00e1c, co gi\u1eadt, thay \u0111\u1ed5i huy\u1ebft \u00e1p qu\u00e1 m\u1ee9c, t\u0103ng nh\u1ecbp tim, s\u1ed1t, run, m\u1edd m\u1eaft, co c\u1ee9ng c\u01a1, \u0111au b\u1ee5ng, bu\u1ed3n n\u00f4n, ti\u00eau ch\u1ea3y. Trong tr\u01b0\u1eddng h\u1ee3p s\u1eed d\u1ee5ng k\u00e9o d\u00e0i, t\u00ecnh tr\u1ea1ng n\u1eb7ng d\u1eabn \u0111\u1ebfn h\u00f4n m\u00ea v\u00e0 th\u1eadm ch\u00ed t\u1eed vong\u00a0<\/span><\/p>\n

4.3 H\u00e0nh \u0111\u1ed9ng ph\u00f2ng ng\u1eeba v\u00e0 c\u00e1ch x\u1eed tr\u00ed\u00a0<\/span><\/h3>\n

N\u00ean \u0111\u1ee3i \u00edt nh\u1ea5t 14 ng\u00e0y sau khi ng\u01b0ng s\u1eed d\u1ee5ng Phenelzine tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Fluoxetine. Ng\u01b0\u1ee3c l\u1ea1i, n\u1ebfu tr\u01b0\u1edbc \u0111\u00f3 \u0111\u00e3 s\u1eed d\u1ee5ng Fluoxetine v\u00e0 hi\u1ec7n \u0111ang b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb b\u1eb1ng\u00a0 Phenelzine, n\u00ean ki\u1ec3m tra v\u1edbi b\u00e1c s\u0129 ho\u1eb7c d\u01b0\u1ee3c s\u0129 \u0111\u1ec3 \u0111\u01b0a ra th\u1eddi gian b\u1eaft \u0111\u1ea7u thu\u1ed1c ph\u00f9 h\u1ee3p an to\u00e0n v\u00ec m\u1ed9t s\u1ed1 thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m c\u00f3 th\u1eddi gian \u0111\u00e0o th\u1ea3i ra kh\u1ecfi c\u01a1 th\u1ec3 l\u00e2u h\u01a1n. Kh\u00f4ng \u0111\u1ed9t ng\u1ed9t ng\u1eebng s\u1eed d\u1ee5ng thu\u1ed1c khi ch\u01b0a c\u00f3 s\u1ef1 th\u00f4ng qua c\u1ee7a b\u00e1c s\u0129\u00a0<\/span><\/p>\n

Ngu\u1ed3n: T\u1ed5ng h\u1ee3p<\/span><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Fluoxetine v\u00e0 Phenelzine l\u00e0 hai lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n t\u00e2m l\u00fd. Tuy nhi\u00ean, khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi hai lo\u1ea1i thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 g\u00e2y ra t\u01b0\u01a1ng t\u00e1c thu\u1ed1c v\u00e0 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ee9c kh\u1ecfe c\u1ee7a b\u1ec7nh nh\u00e2n. Vi\u1ec7c hi\u1ec3u r\u00f5 t\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Fluoxetine v\u00e0 Phenelzine \u0111\u00f3ng […]<\/p>\n","protected":false},"author":54,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[12,33],"tags":[3],"yoast_head":"\nT\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Fluoxetine v\u00e0 Phenelzine - Vinmec<\/title>\n<meta name=\"description\" content=\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Fluoxetine v\u00e0 Phenelzine l\u00e0 m\u1ed9t ch\u1ee7 \u0111\u1ec1 quan tr\u1ecdng trong l\u0129nh v\u1ef1c y h\u1ecdc lu\u00f4n \u0111\u01b0\u1ee3c quan t\u00e2m trong \u0111i\u1ec1u tr\u1ecb cho b\u1ec7nh nh\u00e2n\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa Fluoxetine v\u00e0 Phenelzine - 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