{"id":1871,"date":"2023-04-09T09:41:00","date_gmt":"2023-04-09T02:41:00","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=1871"},"modified":"2023-04-14T12:33:11","modified_gmt":"2023-04-14T05:33:11","slug":"thuoc-sglt2-trong-dieu-tri-suy-tim","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/09\/thuoc-sglt2-trong-dieu-tri-suy-tim\/","title":{"rendered":"Thu\u1ed1c SGLT2 trong \u0111i\u1ec1u tr\u1ecb suy tim"},"content":{"rendered":"

Thu\u1ed1c SGLT2 l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng. \u0110\u1eb7c bi\u1ec7t, trong nh\u1eefng n\u0103m g\u1ea7n \u0111\u00e2y, c\u00e1c nghi\u00ean c\u1ee9u \u0111\u00e3 ch\u1ec9 ra r\u1eb1ng thu\u1ed1c SGLT2 c\u0169ng c\u00f3 th\u1ec3 gi\u00fap c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng tim m\u1ea1ch v\u00e0 gi\u1ea3m nguy c\u01a1 t\u1eed vong do suy tim.<\/span><\/span><\/strong><\/p>\n

Ho\u1ea1t \u0111\u1ed9ng c\u1ee7a thu\u1ed1c\u00a0 l\u00e0 ch\u1ebf \u0111\u1ed9 h\u1ea5p th\u1ee5 glucose t\u1eeb n\u01b0\u1edbc ti\u1ec3u tr\u1edf l\u1ea1i th\u00f4ng qua SGLT2. <\/span>Khi thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng, n\u1ed3ng \u0111\u1ed9 glucose trong m\u00e1u s\u1ebd gi\u1ea3m v\u00e0 glucose s\u1ebd b\u1ecb lo\u1ea1i b\u1ecf qua \u0111\u01b0\u1eddng ti\u1ec3u. <\/span>\u0110i\u1ec1u n\u00e0y gi\u00fap gi\u1ea3m nhi\u1ec7t \u0111\u1ed9 glucose trong m\u00e1u v\u00e0 c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng tim<\/span><\/span>\u00a0m\u1ea1ch.<\/p>\n

\"thu\u1ed1c
thu\u1ed1c sglt2 trong \u0111i\u1ec1u tr\u1ecb suy tim<\/span><\/span><\/figcaption><\/figure>\n

1.Nghi\u00ean c\u1ee9u v\u1ec1 t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c trong \u0111i\u1ec1u tr\u1ecb suy tim.<\/h2>\n

Nghi\u00ean c\u1ee9u EMPEROR-Reduced \u0111\u00e3 ti\u1ebfn h\u00e0nh tr\u00ean h\u01a1n 3.700 b\u1ec7nh nh\u00e2n c\u00f3 suy tim \u1ea5n \u0111\u1ed9ng m\u1ea1ch ch\u1ee7 tr\u00e1i, \u0111\u01b0\u1ee3c chia ng\u1eabu nhi\u00ean nh\u1eadn empagliflozin ho\u1eb7c placebo trong v\u00f2ng 16 th\u00e1ng. K\u1ebft qu\u1ea3 cho th\u1ea5y, empagliflozin gi\u1ea3m 19% nguy c\u01a1 t\u1eed vong do suy tim v\u00e0 gi\u1ea3m 25% nguy c\u01a1 nh\u1eadp vi\u1ec7n do suy tim so v\u1edbi nh\u00f3m placebo.<\/span><\/span><\/p>\n

Ngo\u00e0i ra, nghi\u00ean c\u1ee9u EMPEROR-Reduced c\u00f2n cho th\u1ea5y empagliflozin c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng th\u1eadn, gi\u1ea3m huy\u1ebft \u00e1p v\u00e0 gi\u1ea3m c\u00e2n trong nh\u00f3m b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng thu\u1ed1c.<\/span><\/span><\/p>\n

K\u1ebft qu\u1ea3 c\u1ee7a nghi\u00ean c\u1ee9u n\u00e0y cho th\u1ea5y thu\u1ed1c SGLT2 c\u00f3 ti\u1ec1m n\u0103ng l\u1edbn trong \u0111i\u1ec1u tr\u1ecb suy tim v\u00e0 c\u00f3 th\u1ec3 l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb hi\u1ec7u qu\u1ea3 cho nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 suy tim \u1ea5n \u0111\u1ed9ng m\u1ea1ch ch\u1ee7 tr\u00e1i.<\/span><\/span><\/p>\n

<\/h2>\n

2.C\u00e1c l\u1ee3i \u00edch c\u1ee7a SGLT2 trong \u0111i\u1ec1u tr\u1ecb suy tim.<\/span><\/span><\/h2>\n

C\u00e1c l\u1ee3i \u00edch c\u1ee7a SGLT2 trong \u0111i\u1ec1u tr\u1ecb suy tim bao g\u1ed3m:<\/span><\/span><\/p>\n

Gi\u1ea3m nguy c\u01a1 t\u1eed vong do suy tim: Nh\u1eefng nghi\u00ean c\u1ee9u g\u1ea7n \u0111\u00e2y \u0111\u00e3 ch\u1ec9 ra r\u1eb1ng thu\u1ed1c SGLT2 c\u00f3 th\u1ec3 gi\u1ea3m nguy c\u01a1 t\u1eed vong do suy tim \u1edf c\u00e1c b\u1ec7nh nh\u00e2n c\u00f3 suy tim \u1ea5n \u0111\u1ed9ng m\u1ea1ch ch\u1ee7 tr\u00e1i.<\/span><\/span><\/p>\n

C\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng tim m\u1ea1ch: SGLT2 c\u00f3 t\u00e1c d\u1ee5ng gi\u1ea3m n\u1ed3ng \u0111\u1ed9 glucose trong m\u00e1u, gi\u1ea3m kh\u1ed1i l\u01b0\u1ee3ng m\u00e1u v\u00e0 t\u0103ng kh\u1ea3 n\u0103ng l\u01b0u th\u00f4ng m\u00e1u trong tim. \u0110i\u1ec1u n\u00e0y gi\u00fap c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng tim m\u1ea1ch v\u00e0 gi\u1ea3m nguy c\u01a1 suy tim.<\/span><\/span><\/p>\n

Gi\u1ea3m huy\u1ebft \u00e1p: Thu\u1ed1c SGLT2 c\u00f3 t\u00e1c d\u1ee5ng gi\u1ea3m huy\u1ebft \u00e1p, gi\u00fap c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng tim m\u1ea1ch v\u00e0 gi\u1ea3m nguy c\u01a1 suy tim.<\/span><\/span><\/p>\n

Gi\u1ea3m c\u00e2n: Thu\u1ed1c SGLT2 c\u00f3 t\u00e1c d\u1ee5ng gi\u1ea3m c\u00e2n, gi\u00fap gi\u1ea3m \u00e1p l\u1ef1c l\u00ean tim v\u00e0 gi\u1ea3m nguy c\u01a1 suy tim.<\/span><\/span><\/p>\n

C\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng th\u1eadn: SGLT2 c\u00f3 t\u00e1c d\u1ee5ng gi\u1ea3m n\u1ed3ng \u0111\u1ed9 glucose trong m\u00e1u v\u00e0 gi\u1ea3m \u00e1p l\u1ef1c l\u00ean th\u1eadn, gi\u00fap c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng th\u1eadn v\u00e0 gi\u1ea3m nguy c\u01a1 suy th\u1eadn.<\/span><\/span><\/p>\n

-Gi\u1ea3m nguy c\u01a1 \u0111\u1ed9t qu\u1ef5: Nghi\u00ean c\u1ee9u \u0111\u00e3 ch\u1ec9 ra r\u1eb1ng thu\u1ed1c SGLT2 c\u00f3 th\u1ec3 gi\u1ea3m nguy c\u01a1 \u0111\u1ed9t qu\u1ef5 \u1edf c\u00e1c b\u1ec7nh nh\u00e2n c\u00f3 suy tim.<\/span><\/span><\/p>\n

T\u1ed5ng h\u1ee3p l\u1ea1i, SGLT2 l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c c\u00f3 nhi\u1ec1u l\u1ee3i \u00edch trong \u0111i\u1ec1u tr\u1ecb suy tim v\u00e0 c\u00f3 th\u1ec3 l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb hi\u1ec7u qu\u1ea3 cho nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 suy tim \u1ea5n \u0111\u1ed9ng m\u1ea1ch ch\u1ee7 tr\u00e1i.<\/span><\/span><\/p>\n

3.C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a SGLT2<\/h2>\n

C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a SGLT2 bao g\u1ed3m:<\/p>\n

    \n
  • Ti\u1ec3u nhi\u1ec1u: Do SGLT2 gi\u00fap th\u1eadn lo\u1ea1i b\u1ecf glucose qua \u0111\u01b0\u1eddng ti\u1ec3u, \u0111i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 g\u00e2y ra ti\u1ec3u nhi\u1ec1u v\u00e0 kh\u00e1t n\u01b0\u1edbc.<\/li>\n
  • Nguy c\u01a1 nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng ti\u1ec3u: Do glucose d\u01b0 th\u1eeba trong \u0111\u01b0\u1eddng ti\u1ec3u c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng ti\u1ec3u.<\/li>\n
  • Nguy c\u01a1 vi\u00eam nhi\u1ec5m \u0111\u01b0\u1eddng ti\u00eau h\u00f3a: SGLT2 c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 vi\u00eam nhi\u1ec5m \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, \u0111\u1eb7c bi\u1ec7t l\u00e0 vi\u00eam ru\u1ed9t.<\/li>\n<\/ul>\n

    4. T\u00ecnh h\u00ecnh ph\u00e1t tri\u1ec3n v\u00e0 tri\u1ec3n v\u1ecdng c\u1ee7a thu\u1ed1c trong \u0111i\u1ec1u tr\u1ecb suy tim trong t\u01b0\u01a1ng lai.<\/h2>\n

    Thu\u1ed1c SGLT2 \u0111ang \u0111\u01b0\u1ee3c coi l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ti\u1ec1m n\u0103ng trong vi\u1ec7c c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng tim m\u1ea1ch v\u00e0 gi\u1ea3m nguy c\u01a1 suy tim. Tuy nhi\u00ean, vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c SGLT2 trong \u0111i\u1ec1u tr\u1ecb suy tim v\u1eabn c\u00f2n nhi\u1ec1u b\u1ea5t \u0111\u1ed3ng \u00fd ki\u1ebfn trong c\u1ed9ng \u0111\u1ed3ng y t\u1ebf.<\/span><\/span><\/p>\n

    Tuy nhi\u00ean, c\u00e1c nghi\u00ean c\u1ee9u g\u1ea7n \u0111\u00e2y \u0111\u00e3 cho th\u1ea5y nh\u1eefng l\u1ee3i \u00edch c\u1ee7a thu\u1ed1c SGLT2 trong \u0111i\u1ec1u tr\u1ecb suy tim, \u0111\u1eb7c bi\u1ec7t l\u00e0 trong vi\u1ec7c gi\u1ea3m nguy c\u01a1 t\u1eed vong v\u00e0 c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng th\u1eadn. Vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c SGLT2 trong \u0111i\u1ec1u tr\u1ecb suy tim c\u0169ng \u0111ang \u0111\u01b0\u1ee3c khuy\u1ebfn kh\u00edch v\u00e0 h\u01b0\u1edbng t\u1edbi b\u1edfi c\u00e1c t\u1ed5 ch\u1ee9c y t\u1ebf uy t\u00edn nh\u01b0 Hi\u1ec7p h\u1ed9i Tim m\u1ea1ch Hoa K\u1ef3 (American Heart Association) v\u00e0 Hi\u1ec7p h\u1ed9i \u0110\u00e1i th\u00e1o \u0111\u01b0\u1eddng Hoa K\u1ef3 (American Diabetes Association).<\/span><\/span><\/p>\n

     <\/p>\n

     <\/p>\n

     <\/p>\n","protected":false},"excerpt":{"rendered":"

    Thu\u1ed1c SGLT2 l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng. \u0110\u1eb7c bi\u1ec7t, trong nh\u1eefng n\u0103m g\u1ea7n \u0111\u00e2y, c\u00e1c nghi\u00ean c\u1ee9u \u0111\u00e3 ch\u1ec9 ra r\u1eb1ng thu\u1ed1c SGLT2 c\u0169ng c\u00f3 th\u1ec3 gi\u00fap c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng tim m\u1ea1ch v\u00e0 gi\u1ea3m nguy c\u01a1 t\u1eed vong do suy tim. Ho\u1ea1t \u0111\u1ed9ng c\u1ee7a thu\u1ed1c\u00a0 […]<\/p>\n","protected":false},"author":25,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[7,33],"tags":[3],"yoast_head":"\nThu\u1ed1c SGLT2 trong \u0111i\u1ec1u tr\u1ecb suy tim - Vinmec<\/title>\n<meta name=\"description\" content=\"Thu\u1ed1c SGLT2 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng.Thu\u1ed1c SGLT2 c\u0169ng c\u00f3 th\u1ec3 gi\u00fap \u0111i\u1ec1u tr\u1ecb b\u1ec7nh suy tim.\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Thu\u1ed1c SGLT2 trong \u0111i\u1ec1u tr\u1ecb suy tim - Vinmec\" \/>\n<meta property=\"og:description\" content=\"Thu\u1ed1c SGLT2 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng.Thu\u1ed1c SGLT2 c\u0169ng c\u00f3 th\u1ec3 gi\u00fap \u0111i\u1ec1u tr\u1ecb b\u1ec7nh suy tim.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/09\/thuoc-sglt2-trong-dieu-tri-suy-tim\/\" \/>\n<meta property=\"og:site_name\" content=\"Vinmec\" \/>\n<meta property=\"article:published_time\" content=\"2023-04-09T02:41:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-04-14T05:33:11+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/hinh_1_sglt2-300x170.jpg\" \/>\n<meta name=\"author\" content=\"Thinh Nguyen Hoang\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Thinh Nguyen Hoang\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/09\/thuoc-sglt2-trong-dieu-tri-suy-tim\/\",\"url\":\"https:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/09\/thuoc-sglt2-trong-dieu-tri-suy-tim\/\",\"name\":\"Thu\u1ed1c SGLT2 trong \u0111i\u1ec1u tr\u1ecb suy tim - 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