{"id":18110,"date":"2023-04-12T15:34:05","date_gmt":"2023-04-12T08:34:05","guid":{"rendered":"http:\/\/noithathoaphat.in\/ctv\/?p=18110"},"modified":"2023-04-17T16:31:15","modified_gmt":"2023-04-17T09:31:15","slug":"tuong-tac-thuoc-giua-hoat-chat-warfarin-va-ibuprofen","status":"publish","type":"post","link":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/12\/tuong-tac-thuoc-giua-hoat-chat-warfarin-va-ibuprofen\/","title":{"rendered":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa ho\u1ea1t ch\u1ea5t Warfarin v\u00e0 Ibuprofen"},"content":{"rendered":"

T\u01b0\u01a1ng t\u00e1c thu\u1ed1c c\u00f3 th\u1ec3 x\u1ea3y ra khi s\u1eed d\u1ee5ng hai ho\u1eb7c nhi\u1ec1u lo\u1ea1i thu\u1ed1c c\u00f9ng nhau, khi \u0111\u00f3 ch\u00fang c\u00f3 th\u1ec3 t\u00e1c \u0111\u1ed9ng l\u00ean nhau v\u00e0 thay \u0111\u1ed5i t\u00e1c d\u1ee5ng, hi\u1ec7u qu\u1ea3, ho\u1eb7c \u0111\u1ed9c t\u00ednh c\u1ee7a m\u1ed9t ho\u1eb7c c\u1ea3 hai thu\u1ed1c. V\u00ec v\u1eady, vi\u1ec7c \u0111\u00e1nh gi\u00e1 v\u00e0 theo d\u00f5i t\u01b0\u01a1ng t\u00e1c thu\u1ed1c l\u00e0 r\u1ea5t quan tr\u1ecdng \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 trong vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c cho b\u1ec7nh nh\u00e2n. Trong \u0111\u00f3, t\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa warfarin v\u00e0 ibuprofen l\u00e0 m\u1ed9t v\u1ea5n \u0111\u1ec1 c\u1ea7n \u0111\u01b0\u1ee3c ch\u00fa \u00fd \u0111\u1eb7c bi\u1ec7t trong l\u0129nh v\u1ef1c y t\u1ebf. Sau \u0111\u00e2y, ch\u00fang ta s\u1ebd \u0111i v\u00e0o chi ti\u1ebft v\u1ec1 t\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa warfarin v\u00e0 ibuprofen, c\u00f9ng v\u1edbi c\u00e1c t\u00e1c h\u1ea1i ti\u1ec1m \u1ea9n v\u00e0 c\u00e1ch \u0111\u1ec3 gi\u1ea3m thi\u1ec3u r\u1ee7i ro cho b\u1ec7nh nh\u00e2n.<\/strong><\/p>\n

1. Gi\u1edbi thi\u1ec7u v\u1ec1 warfarin v\u00e0 ibuprofen<\/strong><\/h3>\n

Warfarin l\u00e0 m\u1ed9t thu\u1ed1c kh\u00e1ng vitamin K, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 ng\u0103n ng\u1eeba v\u00e0 \u0111i\u1ec1u tr\u1ecb \u0111\u00f4ng m\u00e1u trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p b\u1ec7nh nh\u00e2n c\u00f3 r\u1ed1i lo\u1ea1n \u0111\u00f4ng m\u00e1u ho\u1eb7c ti\u1ec1n s\u1eed \u0111\u1ed9t qu\u1ef5, suy tim v\u00e0 nh\u1ed3i m\u00e1u c\u01a1 tim.<\/p>\n

Ibuprofen thu\u1ed9c nh\u00f3m thu\u1ed1c kh\u00e1ng vi\u00eam kh\u00f4ng steroid (NSAID), c\u00f3 t\u00e1c d\u1ee5ng ch\u00ednh l\u00e0 ch\u1ed1ng vi\u00eam, h\u1ea1 s\u1ed1t, gi\u1ea3m \u0111au.<\/p>\n

Tuy nhi\u00ean, vi\u1ec7c s\u1eed d\u1ee5ng hai lo\u1ea1i thu\u1ed1c n\u00e0y \u0111\u1ed3ng th\u1eddi c\u00f3 th\u1ec3 g\u00e2y ra t\u01b0\u01a1ng t\u00e1c thu\u1ed1c v\u00e0 d\u1eabn \u0111\u1ebfn c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng cho b\u1ec7nh nh\u00e2n. T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/a> gi\u1eefa warfarin v\u00e0 ibuprofen c\u00f3 m\u1ee9c \u0111\u1ed9 \u1ea3nh h\u01b0\u1edfng nghi\u00eam tr\u1ecdng v\u00e0 c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a warfarin trong vi\u1ec7c ng\u0103n ng\u1eeba \u0111\u00f4ng m\u00e1u, t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u v\u00e0 c\u1ea7n \u0111\u01b0\u1ee3c qu\u1ea3n l\u00fd v\u00e0 theo d\u00f5i c\u1ea9n th\u1eadn.<\/p>\n

2. M\u1ee9c \u0111\u1ed9 t\u00e1c h\u1ea1i c\u1ee7a <\/strong>t\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa warfarin v\u00e0 ibuprofen<\/span><\/strong><\/h3>\n

M\u1ee9c \u0111\u1ed9 t\u00e1c h\u1ea1i khi s\u1eed d\u1ee5ng warfarin v\u00e0 ibuprofen c\u00f9ng l\u00fac l\u00e0 kh\u00e1 cao. Vi\u1ec7c s\u1eed d\u1ee5ng hai lo\u1ea1i thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn nguy c\u01a1 ch\u1ea3y m\u00e1u nghi\u00eam tr\u1ecdng v\u00e0 c\u00e1c bi\u1ebfn ch\u1ee9ng li\u00ean quan \u0111\u1ebfn \u0111\u00f4ng m\u00e1u. Ngo\u00e0i ra, t\u01b0\u01a1ng t\u00e1c thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a warfarin trong vi\u1ec7c ng\u0103n ng\u1eeba \u0111\u00f4ng m\u00e1u, \u0111\u1ed3ng th\u1eddi t\u0103ng nguy c\u01a1 \u0111\u1ed9t qu\u1ef5 v\u00e0 tai bi\u1ebfn li\u00ean quan \u0111\u1ebfn \u0111\u00f4ng m\u00e1u. Do \u0111\u00f3, vi\u1ec7c s\u1eed d\u1ee5ng warfarin v\u00e0 ibuprofen c\u00f9ng l\u00fac c\u1ea7n \u0111\u01b0\u1ee3c c\u00e2n nh\u1eafc k\u1ef9 l\u01b0\u1ee1ng v\u00e0 h\u1ea1n ch\u1ebf trong tr\u01b0\u1eddng h\u1ee3p c\u1ea7n thi\u1ebft.<\/p>\n

Theo nghi\u00ean c\u1ee9u c\u1ee7a C\u1ee5c Qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m Hoa K\u1ef3 (FDA), s\u1eed d\u1ee5ng ibuprofen c\u00f9ng v\u1edbi warfarin c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u l\u00ean \u0111\u1ebfn 50%. \u0110i\u1ec1u n\u00e0y \u0111\u1eb7c bi\u1ec7t \u0111\u00e1ng lo ng\u1ea1i \u0111\u1ed1i v\u1edbi c\u00e1c b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed ch\u1ea3y m\u00e1u ho\u1eb7c \u0111ang s\u1eed d\u1ee5ng c\u00e1c lo\u1ea1i thu\u1ed1c kh\u00e1c c\u00f3 t\u00e1c d\u1ee5ng ch\u1ed1ng \u0111\u00f4ng m\u00e1u, nh\u01b0 aspirin hay clopidogrel.<\/p>\n

3. C\u01a1 ch\u1ebf x\u1ea3y ra <\/span><\/span><\/strong>t\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa warfarin v\u00e0 ibuprofen<\/span><\/strong><\/h3>\n

C\u01a1 ch\u1ebf t\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa warfarin v\u00e0 ibuprofen li\u00ean quan \u0111\u1ebfn s\u1ef1 c\u1ea1nh tranh g\u1eafn k\u1ebft c\u1ee7a c\u00e1c thu\u1ed1c tr\u00ean protein huy\u1ebft t\u01b0\u01a1ng. Warfarin \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a b\u1edfi enzym CYP2C9 trong gan \u0111\u1ec3 t\u1ea1o ra c\u00e1c ch\u1ea5t c\u00f3 ho\u1ea1t t\u00ednh anticoagulant. Ibuprofen c\u0169ng \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a b\u1edfi CYP2C9, v\u00e0 do \u0111\u00f3 khi \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi warfarin, ibuprofen c\u00f3 th\u1ec3 c\u1ea1nh tranh v\u1edbi warfarin trong vi\u1ec7c g\u1eafn k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng. Warfarin k\u1ebft h\u1ee3p v\u1edbi protein m\u00e1u c\u00f3 t\u00ean l\u00e0 albumin \u0111\u1ec3 v\u1eadn chuy\u1ec3n \u0111\u1ebfn c\u00e1c m\u00f4 c\u1ea7n thi\u1ebft. Ibuprofen c\u0169ng c\u00f3 kh\u1ea3 n\u0103ng k\u1ebft h\u1ee3p v\u1edbi albumin v\u00e0 c\u1ea1nh tranh v\u1edbi warfarin \u0111\u1ec3 k\u1ebft h\u1ee3p v\u1edbi protein n\u00e0y. Khi ibuprofen c\u1ea1nh tranh v\u1edbi warfarin \u0111\u1ec3 k\u1ebft h\u1ee3p v\u1edbi albumin, l\u00e0m gi\u1ea3m l\u01b0\u1ee3ng warfarin \u0111\u01b0\u1ee3c li\u00ean k\u1ebft v\u1edbi protein v\u00e0 t\u0103ng s\u1ef1 t\u1ed3n \u0111\u1ecdng c\u1ee7a warfarin trong c\u01a1 th\u1ec3, g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nh\u01b0 ch\u1ea3y m\u00e1u.<\/p>\n

4. T\u00e1c h\u1ea1i\/ H\u1eadu qu\u1ea3 c\u1ee7a <\/span><\/span><\/strong>t\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa warfarin v\u00e0 ibuprofen<\/span><\/strong><\/h3>\n

Khi s\u1eed d\u1ee5ng warfarin v\u00e0 ibuprofen c\u00f9ng l\u00fac, nguy c\u01a1 ch\u1ea3y m\u00e1u c\u00f3 th\u1ec3 t\u0103ng \u0111\u00e1ng k\u1ec3. Ibuprofen l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid (NSAID), c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m gi\u1ea3m \u0111au v\u00e0 vi\u00eam. Tuy nhi\u00ean, n\u00f3 c\u0169ng l\u00e0m gi\u1ea3m kh\u1ea3 n\u0103ng c\u1ee7a c\u00e1c t\u1ebf b\u00e0o m\u00e1u \u0111\u1ec3 g\u1eafn k\u1ebft v\u1edbi nhau, g\u00e2y ra t\u00e1c d\u1ee5ng ph\u1ee5 ch\u1ea3y m\u00e1u. Warfarin l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u, l\u00e0m gi\u1ea3m kh\u1ea3 n\u0103ng \u0111\u00f4ng m\u00e1u c\u1ee7a m\u00e1u b\u1eb1ng c\u00e1ch ng\u0103n ch\u1eb7n s\u1ea3n xu\u1ea5t c\u00e1c y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u trong c\u01a1 th\u1ec3. Khi s\u1eed d\u1ee5ng c\u00f9ng l\u00fac v\u1edbi ibuprofen, warfarin c\u00f3 th\u1ec3 kh\u00f4ng \u0111\u1ee7 m\u1ea1nh \u0111\u1ec3 ng\u0103n ch\u1eb7n qu\u00e1 tr\u00ecnh \u0111\u00f4ng m\u00e1u, d\u1eabn \u0111\u1ebfn nguy c\u01a1 ch\u1ea3y m\u00e1u, \u0111\u1eb7c bi\u1ec7t l\u00e0 khi s\u1eed d\u1ee5ng li\u1ec1u cao v\u00e0 th\u01b0\u1eddng xuy\u00ean trong th\u1eddi gian d\u00e0i. \u0110i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn c\u00e1c bi\u1ebfn ch\u1ee9ng nghi\u00eam tr\u1ecdng nh\u01b0 ch\u1ea3y m\u00e1u ti\u00eau h\u00f3a, ch\u1ea3y m\u00e1u n\u00e3o, ch\u1ea3y m\u00e1u d\u01b0\u1edbi da, ch\u1ea3y m\u00e1u \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u, v\u00e0 th\u1eadm ch\u00ed g\u00e2y t\u1eed vong. \u0110i\u1ec1u n\u00e0y \u0111\u1eb7c bi\u1ec7t \u0111\u00e1ng lo ng\u1ea1i \u0111\u1ed1i v\u1edbi nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb c\u00e1c b\u1ec7nh l\u00fd li\u00ean quan \u0111\u1ebfn \u0111\u00f4ng m\u00e1u, nh\u01b0 nh\u1ed3i m\u00e1u c\u01a1 tim, \u0111\u1ed9t qu\u1ef5, hay b\u1ec7nh v\u1ec1 van tim.<\/p>\n

\"thuoc-warfarin\"
Thu\u1ed1c warfarin<\/figcaption><\/figure>\n

5. H\u00e0nh \u0111\u1ed9ng ph\u00f2ng ng\u1eeba \/ X\u1eed tr\u00ed\u00a0<\/strong><\/h3>\n

Vi\u1ec7c ph\u00f2ng ng\u1eeba v\u00e0 x\u1eed tr\u00ed t\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa warfarin v\u00e0 ibuprofen l\u00e0 r\u1ea5t quan tr\u1ecdng \u0111\u1ec3 gi\u1ea3m thi\u1ec3u nguy c\u01a1 ch\u1ea3y m\u00e1u v\u00e0 \u0111\u1ea3m b\u1ea3o hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb. C\u00e1c h\u00e0nh \u0111\u1ed9ng c\u1ee5 th\u1ec3 bao g\u1ed3m:<\/p>\n

    \n
  • \u0110\u00e1nh gi\u00e1 t\u01b0\u01a1ng t\u00e1c thu\u1ed1c: Tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng ibuprofen, b\u1ec7nh nh\u00e2n n\u00ean th\u00f4ng b\u00e1o cho b\u00e1c s\u0129 ho\u1eb7c nh\u00e0 \u0111i\u1ec1u tr\u1ecb v\u1ec1 c\u00e1c lo\u1ea1i thu\u1ed1c \u0111ang s\u1eed d\u1ee5ng, bao g\u1ed3m c\u1ea3 warfarin. B\u00e1c s\u0129 c\u1ea7n \u0111\u00e1nh gi\u00e1 t\u01b0\u01a1ng t\u00e1c gi\u1eefa c\u00e1c thu\u1ed1c n\u00e0y \u0111\u1ec3 \u0111\u01b0a ra quy\u1ebft \u0111\u1ecbnh s\u1eed d\u1ee5ng th\u00edch h\u1ee3p.<\/li>\n
  • T\u01b0 v\u1ea5n cho b\u1ec7nh nh\u00e2n: B\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n v\u1ec1 t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a thu\u1ed1c v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng ch\u00fang m\u1ed9t c\u00e1ch h\u1ee3p l\u00fd \u0111\u1ec3 gi\u1ea3m thi\u1ec3u nguy c\u01a1 t\u01b0\u01a1ng t\u00e1c thu\u1ed1c.<\/li>\n
  • Thay \u0111\u1ed5i li\u1ec1u l\u01b0\u1ee3ng thu\u1ed1c: N\u1ebfu b\u1ec7nh nh\u00e2n c\u1ea7n s\u1eed d\u1ee5ng c\u1ea3 hai lo\u1ea1i thu\u1ed1c, b\u00e1c s\u0129 c\u00f3 th\u1ec3 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u l\u01b0\u1ee3ng c\u1ee7a warfarin \u0111\u1ec3 gi\u1ea3m nguy c\u01a1 xu\u1ea5t hi\u1ec7n t\u01b0\u01a1ng t\u00e1c thu\u1ed1c. \u0110i\u1ec1u n\u00e0y c\u1ea7n \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n d\u01b0\u1edbi s\u1ef1 gi\u00e1m s\u00e1t c\u1ee7a b\u00e1c s\u0129.<\/li>\n
  • Theo d\u00f5i \u0111\u1ecbnh k\u1ef3 c\u00e1c ch\u1ec9 s\u1ed1 \u0111\u00f4ng m\u00e1u: B\u1ec7nh nh\u00e2n c\u1ea7n th\u01b0\u1eddng xuy\u00ean ki\u1ec3m tra c\u00e1c ch\u1ec9 s\u1ed1 \u0111\u00f4ng m\u00e1u c\u1ee7a m\u00ecnh \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 trong \u0111i\u1ec1u tr\u1ecb. Vi\u1ec7c theo d\u00f5i n\u00e0y c\u00f3 th\u1ec3 gi\u00fap ph\u00e1t hi\u1ec7n c\u00e1c v\u1ea5n \u0111\u1ec1 li\u00ean quan \u0111\u1ebfn \u0111\u00f4ng m\u00e1u s\u1edbm v\u00e0 \u0111\u01b0a ra c\u00e1c bi\u1ec7n ph\u00e1p x\u1eed tr\u00ed k\u1ecbp th\u1eddi.<\/li>\n
  • T\u00ecm ki\u1ebfm c\u00e1c ph\u01b0\u01a1ng th\u1ee9c gi\u1ea3m \u0111au v\u00e0 kh\u00e1ng vi\u00eam kh\u00e1c: N\u1ebfu ibuprofen kh\u00f4ng th\u1ec3 s\u1eed d\u1ee5ng trong tr\u01b0\u1eddng h\u1ee3p n\u00e0y, b\u00e1c s\u0129 c\u00f3 th\u1ec3 t\u00ecm ki\u1ebfm c\u00e1c ph\u01b0\u01a1ng th\u1ee9c gi\u1ea3m \u0111au v\u00e0 kh\u00e1ng vi\u00eam kh\u00e1c \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh nh\u00e2n.<\/li>\n<\/ul>\n

    Tuy\u00ean b\u1ed1 mi\u1ec5n tr\u1eeb tr\u00e1ch nhi\u1ec7m:<\/strong><\/h3>\n

    C\u00e1c quy\u1ebft \u0111\u1ecbnh li\u00ean quan \u0111\u1ebfn \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c ph\u1ea3i d\u1ef1a tr\u00ean \u0111\u00e1nh gi\u00e1 \u0111\u1ed9c l\u1eadp c\u1ee7a b\u00e1c s\u0129 l\u00e2m s\u00e0ng, thay \u0111\u1ed5i th\u00f4ng tin v\u1ec1 m\u1ed9t lo\u1ea1i thu\u1ed1c (v\u00ed d\u1ee5: Th\u00f4ng tin \u0111\u01b0\u1ee3c trong t\u00e0i li\u1ec7u v\u00e0 th\u00f4ng tin s\u1ea3n ph\u1ea9m m\u1edbi nh\u1ea5t c\u1ee7a nh\u00e0 s\u1ea3n xu\u1ea5t) v\u00e0 thay \u0111\u1ed5i th\u1ef1c h\u00e0nh y t\u1ebf.<\/p>\n","protected":false},"excerpt":{"rendered":"

    T\u01b0\u01a1ng t\u00e1c thu\u1ed1c c\u00f3 th\u1ec3 x\u1ea3y ra khi s\u1eed d\u1ee5ng hai ho\u1eb7c nhi\u1ec1u lo\u1ea1i thu\u1ed1c c\u00f9ng nhau, khi \u0111\u00f3 ch\u00fang c\u00f3 th\u1ec3 t\u00e1c \u0111\u1ed9ng l\u00ean nhau v\u00e0 thay \u0111\u1ed5i t\u00e1c d\u1ee5ng, hi\u1ec7u qu\u1ea3, ho\u1eb7c \u0111\u1ed9c t\u00ednh c\u1ee7a m\u1ed9t ho\u1eb7c c\u1ea3 hai thu\u1ed1c. V\u00ec v\u1eady, vi\u1ec7c \u0111\u00e1nh gi\u00e1 v\u00e0 theo d\u00f5i t\u01b0\u01a1ng t\u00e1c thu\u1ed1c l\u00e0 r\u1ea5t […]<\/p>\n","protected":false},"author":58,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[12,33],"tags":[3],"yoast_head":"\nT\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa ho\u1ea1t ch\u1ea5t Warfarin v\u00e0 Ibuprofen - Vinmec<\/title>\n<meta name=\"description\" content=\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa warfarin v\u00e0 ibuprofen c\u00f3 m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng v\u00e0 c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a warfarin trong vi\u1ec7c ng\u0103n ng\u1eeba \u0111\u00f4ng m\u00e1u\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa ho\u1ea1t ch\u1ea5t Warfarin v\u00e0 Ibuprofen - Vinmec\" \/>\n<meta property=\"og:description\" content=\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa warfarin v\u00e0 ibuprofen c\u00f3 m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng v\u00e0 c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a warfarin trong vi\u1ec7c ng\u0103n ng\u1eeba \u0111\u00f4ng m\u00e1u\" \/>\n<meta property=\"og:url\" content=\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/12\/tuong-tac-thuoc-giua-hoat-chat-warfarin-va-ibuprofen\/\" \/>\n<meta property=\"og:site_name\" content=\"Vinmec\" \/>\n<meta property=\"article:published_time\" content=\"2023-04-12T08:34:05+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-04-17T09:31:15+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/warfarin-300x300.png\" \/>\n<meta name=\"author\" content=\"Nguy\u1ec5n Anh Khoa\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Nguy\u1ec5n Anh Khoa\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/12\/tuong-tac-thuoc-giua-hoat-chat-warfarin-va-ibuprofen\/\",\"url\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/12\/tuong-tac-thuoc-giua-hoat-chat-warfarin-va-ibuprofen\/\",\"name\":\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa ho\u1ea1t ch\u1ea5t Warfarin v\u00e0 Ibuprofen - Vinmec\",\"isPartOf\":{\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/#website\"},\"datePublished\":\"2023-04-12T08:34:05+00:00\",\"dateModified\":\"2023-04-17T09:31:15+00:00\",\"author\":{\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/726baba71876c9e891dc999dda00fd20\"},\"description\":\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa warfarin v\u00e0 ibuprofen c\u00f3 m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng v\u00e0 c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a warfarin trong vi\u1ec7c ng\u0103n ng\u1eeba \u0111\u00f4ng m\u00e1u\",\"breadcrumb\":{\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/12\/tuong-tac-thuoc-giua-hoat-chat-warfarin-va-ibuprofen\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/12\/tuong-tac-thuoc-giua-hoat-chat-warfarin-va-ibuprofen\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/12\/tuong-tac-thuoc-giua-hoat-chat-warfarin-va-ibuprofen\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"http:\/\/noithathoaphat.in\/ctv\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa ho\u1ea1t ch\u1ea5t Warfarin v\u00e0 Ibuprofen\"}]},{\"@type\":\"WebSite\",\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/#website\",\"url\":\"http:\/\/noithathoaphat.in\/ctv\/\",\"name\":\"Vinmec\",\"description\":\"H\u1ec7 th\u1ed1ng Y t\u1ebf Vinmec\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"http:\/\/noithathoaphat.in\/ctv\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/726baba71876c9e891dc999dda00fd20\",\"name\":\"Nguy\u1ec5n Anh Khoa\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/image\/\",\"url\":\"http:\/\/1.gravatar.com\/avatar\/76de8ba430c9c90efea3369de655292c?s=96&d=mm&r=g\",\"contentUrl\":\"http:\/\/1.gravatar.com\/avatar\/76de8ba430c9c90efea3369de655292c?s=96&d=mm&r=g\",\"caption\":\"Nguy\u1ec5n Anh Khoa\"},\"url\":\"http:\/\/noithathoaphat.in\/ctv\/index.php\/author\/kevin2832001gmail-com\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa ho\u1ea1t ch\u1ea5t Warfarin v\u00e0 Ibuprofen - Vinmec","description":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa warfarin v\u00e0 ibuprofen c\u00f3 m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng v\u00e0 c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a warfarin trong vi\u1ec7c ng\u0103n ng\u1eeba \u0111\u00f4ng m\u00e1u","robots":{"index":"noindex","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"og_locale":"en_US","og_type":"article","og_title":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa ho\u1ea1t ch\u1ea5t Warfarin v\u00e0 Ibuprofen - Vinmec","og_description":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa warfarin v\u00e0 ibuprofen c\u00f3 m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng v\u00e0 c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a warfarin trong vi\u1ec7c ng\u0103n ng\u1eeba \u0111\u00f4ng m\u00e1u","og_url":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/12\/tuong-tac-thuoc-giua-hoat-chat-warfarin-va-ibuprofen\/","og_site_name":"Vinmec","article_published_time":"2023-04-12T08:34:05+00:00","article_modified_time":"2023-04-17T09:31:15+00:00","og_image":[{"url":"http:\/\/noithathoaphat.in\/ctv\/wp-content\/uploads\/2023\/04\/warfarin-300x300.png"}],"author":"Nguy\u1ec5n Anh Khoa","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Nguy\u1ec5n Anh Khoa","Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/12\/tuong-tac-thuoc-giua-hoat-chat-warfarin-va-ibuprofen\/","url":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/12\/tuong-tac-thuoc-giua-hoat-chat-warfarin-va-ibuprofen\/","name":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa ho\u1ea1t ch\u1ea5t Warfarin v\u00e0 Ibuprofen - Vinmec","isPartOf":{"@id":"http:\/\/noithathoaphat.in\/ctv\/#website"},"datePublished":"2023-04-12T08:34:05+00:00","dateModified":"2023-04-17T09:31:15+00:00","author":{"@id":"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/726baba71876c9e891dc999dda00fd20"},"description":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa warfarin v\u00e0 ibuprofen c\u00f3 m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng v\u00e0 c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a warfarin trong vi\u1ec7c ng\u0103n ng\u1eeba \u0111\u00f4ng m\u00e1u","breadcrumb":{"@id":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/12\/tuong-tac-thuoc-giua-hoat-chat-warfarin-va-ibuprofen\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/12\/tuong-tac-thuoc-giua-hoat-chat-warfarin-va-ibuprofen\/"]}]},{"@type":"BreadcrumbList","@id":"http:\/\/noithathoaphat.in\/ctv\/index.php\/2023\/04\/12\/tuong-tac-thuoc-giua-hoat-chat-warfarin-va-ibuprofen\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"http:\/\/noithathoaphat.in\/ctv\/"},{"@type":"ListItem","position":2,"name":"T\u01b0\u01a1ng t\u00e1c thu\u1ed1c gi\u1eefa ho\u1ea1t ch\u1ea5t Warfarin v\u00e0 Ibuprofen"}]},{"@type":"WebSite","@id":"http:\/\/noithathoaphat.in\/ctv\/#website","url":"http:\/\/noithathoaphat.in\/ctv\/","name":"Vinmec","description":"H\u1ec7 th\u1ed1ng Y t\u1ebf Vinmec","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"http:\/\/noithathoaphat.in\/ctv\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Person","@id":"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/726baba71876c9e891dc999dda00fd20","name":"Nguy\u1ec5n Anh Khoa","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"http:\/\/noithathoaphat.in\/ctv\/#\/schema\/person\/image\/","url":"http:\/\/1.gravatar.com\/avatar\/76de8ba430c9c90efea3369de655292c?s=96&d=mm&r=g","contentUrl":"http:\/\/1.gravatar.com\/avatar\/76de8ba430c9c90efea3369de655292c?s=96&d=mm&r=g","caption":"Nguy\u1ec5n Anh Khoa"},"url":"http:\/\/noithathoaphat.in\/ctv\/index.php\/author\/kevin2832001gmail-com\/"}]}},"_links":{"self":[{"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/posts\/18110"}],"collection":[{"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/users\/58"}],"replies":[{"embeddable":true,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/comments?post=18110"}],"version-history":[{"count":12,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/posts\/18110\/revisions"}],"predecessor-version":[{"id":20925,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/posts\/18110\/revisions\/20925"}],"wp:attachment":[{"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/media?parent=18110"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/categories?post=18110"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/noithathoaphat.in\/ctv\/index.php\/wp-json\/wp\/v2\/tags?post=18110"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}